URMC / Center for Translational Neuromedicine / Publications Publications Iden CRMustafa SMØgaard NHenriksen TJensen SØAhlborn LBEgebjerg KBaeksgaard LGarbyal RSNedergaard MKAchiam MPAndersen CLMau-Sørensen M Circulating tumor DNA predicts recurrence and survival in patients with resectable gastric and gastroesophageal junction cancer.; Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2024 Oct 05. Asiminas AGomolka RSGregoriades SHirase HNedergaard MBeinlich FRM Protocol to study oxygen dynamics in the in vivo mouse brain using bioluminescence microscopy.; STAR protocols; Vol 5(4), pp. 103334. 2024 Sep 25. Cao QYang SWang XSun HChen WWang YGao JWu YYang QChen XYuan SXiao MNedergaard MHuo YLiu Q Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer's disease.; The Journal of experimental medicine; Vol 221(11). 2024 Sep 24. Kroesbergen ERiesselmann LVGomolka RSPlá VEsmail TStenmo VHKovács ERNielsen ESGoldman SANedergaard MWeikop PMori Y Glymphatic clearance is enhanced during sleep.; bioRxiv : the preprint server for biology. 2024 Sep 15. Plá VBitsika SGiannetto MJLadrón-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Response to Commentary on "Structural characterization of SLYM - a 4th meningeal membrane" by Julie Siegenthaler and Christer Betsholtz.; Fluids and barriers of the CNS; Vol 21(1), pp. 70. 2024 Sep 09. Xu CNedergaard MFowell DJFriedl PJi N Multiphoton fluorescence microscopy for in vivo imaging.; Cell; Vol 187(17), pp. 4458-4487. 2024 Aug 22. Du TRaghunandan AMestre HPlá VLiu GLadrón-de-Guevara ANewbold ETobin PGahn-Martinez DPattanayak SHuang QPeng WNedergaard MKelley DH Restoration of cervical lymphatic vessel function in aging rescues cerebrospinal fluid drainage.; Nature aging. 2024 Aug 15. Smyth LCDBeschorner NNedergaard MKipnis J Cellular Contributions to Glymphatic and Lymphatic Waste Clearance in the Brain.; Cold Spring Harbor perspectives in biology. 2024 Aug 12. Wostyn PNedergaard M The potential influence of sleep on translaminar pressure dynamics and ocular glymphatic outflow in microgravity: implications for optic disc edema in astronauts.; Eye (London, England). 2024 Jul 30. Kaag Rasmussen MMøllgård KBork PARWeikop PEsmail TDrici LWewer Albrechtsen NJCarlsen JFHuynh NPTGhitani NMann MGoldman SAMori YChesler ATNedergaard M Trigeminal ganglion neurons are directly activated by influx of CSF solutes in a migraine model.; Science (New York, N.Y.); Vol 385(6704), pp. 80-86. 2024 Jul 04. Plá VBitsika SGiannetto MJLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K In response to "An "outer subarachnoid space": fact or artifact? A commentary on "Structural characterization of SLYM: a 4th meningeal membrane" fluids and barriers of the CNS (2023) 20:93 by V. Plá et al.".; Fluids and barriers of the CNS; Vol 21(1), pp. 49. 2024 Jun 03. Ge GRSong WGiannetto MJRolland JPNedergaard MParker KJ Mouse Brain Elastography Changes with Sleep/Wake Cycles, Aging, and Alzheimer's Disease.; NeuroImage. 2024 May 30. Persson NDÅLohela TJMortensen KNRosenholm MLi QWeikop PNedergaard MLilius TO Anesthesia blunts carbon dioxide effects on glymphatic cerebrospinal fluid dynamics in mechanically ventilated rats.; Anesthesiology. 2024 May 24. Delle CWang XNedergaard M The Ocular Glymphatic System-Current Understanding and Future Perspectives.; International journal of molecular sciences; Vol 25(11). 2024 May 24. Zhou XAMan WLiu XChoi SJiang YHike DCid LGLin CNedergaard MYu X Mapping glymphatic solute transportation through the perivascular space of hippocampal arterioles with 14 Tesla MRI.; bioRxiv : the preprint server for biology. 2024 May 20. Mader THGibson CRWostyn PNedergaard M Enlargement of Perivascular Spaces as a Downstream Consequence of Spaceflight Analog-Induced Alterations in Cerebral Venous Hemodynamics.; AJNR. American journal of neuroradiology; Vol 45(5), pp. E6. 2024 May 09. Mariani JNMansky BMadsen PMSalinas DKesmen DHuynh NPTKuypers NJKesel ERBates JPayne CChandler-Militello DBenraiss AGoldman SA Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells.; Nature communications; Vol 15(1), pp. 3873. 2024 May 08. Wostyn PNedergaard M A new look at ocular glymphatic transport in space.; Journal of applied physiology (Bethesda, Md. : 1985); Vol 136(5), pp. 1129-1130. 2024 May 01. Deng SHu YChen SXue YYao DSun QNedergaard MWang WDing F Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice.; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2024 Apr 19. van Osch MJPWåhlin AScheyhing PMossige IHirschler LEklund AMogensen KGomolka RRadbruch AQvarlander SDecker ANedergaard MMori YEide PKDeike KRingstad G Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and blood.; NMR in biomedicine. 2024 Apr 18. Bork PARHauglund NLMori YMøllgård KHjorth PGNedergaard M Modeling of brain efflux: Constraints of brain surfaces.; Proceedings of the National Academy of Sciences of the United States of America; Vol 121(16), pp. e2318444121. 2024 Apr 10. Beinlich FRMAsiminas AUntiet VBojarowska ZPlá VSigurdsson BTimmel VGehrig LGraber MHHirase HNedergaard M Oxygen imaging of hypoxic pockets in the mouse cerebral cortex.; Science (New York, N.Y.); Vol 383(6690), pp. 1471-1478. 2024 Mar 28. Delle CWang XGiannetto MNewbold EPeng WGomolka RSLadrón-de-Guevara ACankar NSchiøler Nielsen EKjaerby CWeikop PMori YNedergaard M Transient but not chronic hyperglycemia accelerates ocular glymphatic transport.; Fluids and barriers of the CNS; Vol 21(1), pp. 26. 2024 Mar 12. Ding FSun QLong CRasmussen RNPeng SXu QKang NSong WWeikop PGoldman SANedergaard M Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration.; Brain : a journal of neurology. 2024 Mar 11. Hablitz LNedergaard M Synchronized neuronal activity drives waste fluid flow.; Nature. 2024 Feb 28. Giannetto MJGomolka RSGahn-Martinez DNewbold EJBork PARChang EGresser MThompson TMori YNedergaard M Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271.; Glia. 2024 Feb 16. Beschorner NNedergaard M Glymphatic system dysfunction in neurodegenerative diseases.; Current opinion in neurology. 2024 Feb 13. Franklin RJMBodini BGoldman SA Remyelination in the Central Nervous System.; Cold Spring Harbor perspectives in biology. 2024 Feb 05. Patel KSTessema KKKawaguchi RDudley LAlvarado AGMuthukrishnan SDPerryman THagiwara ASwarup VLiau LMWang ACYong WGeschwind DHNakano IGoldman SAEverson RGEllingson BMKornblum HI Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma.; Neuro-oncology advances; Vol 6(1), pp. vdae005. 2024 Jan 25. Eisen ANedergaard MGray EKiernan MC THE GLYMPHATIC SYSTEM AND AMYOTROPHIC LATERAL SCLEROSIS.; Progress in neurobiology. 2024 Jan 22. Zhao LQiu ZYang ZXu LPearce TMWu QYang KLi FSaulnier OFei FYu HGimple RCVaradharajan VLiu JHendrikse LDFong VWang WZhang JLv DLee DLehrich BMJin COuyang LDixit DWu HWang XSloan AEWang XHuan TMark Brown JGoldman SATaylor MDZhou SRich JN Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.; Nature cancer. 2024 Jan 03. Hussain RNedergaard M Managing noradrenaline after traumatic brain injury.; Clinical and translational medicine; Vol 14(1), pp. e1562. 2024 Jan. Goldman SAFranklin RJMOsorio J Stem and progenitor cell-based therapy of myelin disorders.; Handbook of clinical neurology; Vol 205, pp. 283-295. 2024. Untiet VNedergaard MVerkhratsky A Astrocyte chloride, excitatory-inhibitory balance and epilepsy.; Neural regeneration research; Vol 19(9), pp. 1887. 2023 Dec 15. Dietz AGWeikop PHauglund NAndersen MPetersen NCRose LHirase HNedergaard M Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(40), pp. e2305071120. 2023 Sep 29. Hussain RGraham UElder ANedergaard M Air pollution, glymphatic impairment, and Alzheimer's disease.; Trends in neurosciences. 2023 Sep 28. Gan YHolstein-Rønsbo SNedergaard MBoster KASThomas JHKelley DH Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism.; Journal of the Royal Society, Interface; Vol 20(206), pp. 20230288. 2023 Sep 20. Takasugi MOhtani NTakemura KEmmrich SZakusilo FTYoshida YKutsukake NMariani JNWindrem MSChandler-Militello DGoldman SASatoh JIto SSeluanov AGorbunova V CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.; Cell reports; Vol 42(9), pp. 113130. 2023 Sep 13. Holstein-Rønsbo SGan YGiannetto MJRasmussen MKSigurdsson BBeinlich FRMRose LUntiet VHablitz LMKelley DHNedergaard M Publisher Correction: Glymphatic influx and clearance are accelerated by neurovascular coupling.; Nature neuroscience. 2023 Sep 04. Ozawa KNagao MKonno AIwai YVittani MKusk PMishima THirai HNedergaard MHirase H Astrocytic GPCR-Induced Ca2+ Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes.; International journal of molecular sciences; Vol 24(17). 2023 Sep 02. Staudt MShalgunov VNedergaard MHerth MM Development of 11 C-labeled CRANAD-102 for positron emission tomography imaging of soluble Aβ-species.; Journal of labelled compounds & radiopharmaceuticals. 2023 Aug 31. Andersen MTsopanidou ARadovanovic TCompere VNHauglund NNedergaard MKjaerby C Using Fiber Photometry in Mice to Estimate Fluorescent Biosensor Levels During Sleep.; Bio-protocol; Vol 13(15), pp. e4734. 2023 Aug 05. Kim DGan YNedergaard MKelley DHTithof J Image Analysis Techniques for In Vivo Quantification of Cerebrospinal Fluid Flow.; bioRxiv : the preprint server for biology. 2023 Jul 24. Miyakoshi LMStæger FFLi QPan CXie LKang HPavan CDang JSun QErtürk ANedergaard M The state of brain activity modulates cerebrospinal fluid transport.; Progress in neurobiology. 2023 Jul 21. Vieira RMariani JNHuynh NPTStephensen HJTSolly RTate ASchanz SCotrupi NMousaei MSporring JBenraiss AGoldman SA Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain.; Nature biotechnology. 2023 Jul 17. Raicevic NForer JMLadrón-de-Guevara ADu TNedergaard MKelley DHBoster K Sizes and shapes of perivascular spaces surrounding murine pial arteries.; Fluids and barriers of the CNS; Vol 20(1), pp. 56. 2023 Jul 17. Bork PARLadrón-de-Guevara AChristensen AHJensen KHNedergaard MBohr T Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow.; Journal of the Royal Society, Interface; Vol 20(204), pp. 20230050. 2023 Jul 12. Vittani MKnak PAGFukuda MNagao MWang XKjaerby CKonno AHirai HNedergaard MHirase H Virally induced CRISPR/Cas9-based knock-in of fluorescent albumin allows long-term visualization of cerebral circulation in infant and adult mice.; bioRxiv : the preprint server for biology. 2023 Jul 10. Mathiesen BKMiyakoshi LMCederroth CRTserga EVersteegh CBork PARHauglund NLGomolka RSMori YEdvall NKRouse SMøllgård KHolt JRNedergaard MCanlon B Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.; Science translational medicine; Vol 15(702), pp. eabq3916. 2023 Jun 28. Villanueva CBStephensen HJTMokso RBenraiss ASporring JGoldman SA Astrocytic engagement of the corticostriatal synaptic cleft is disrupted in a mouse model of Huntington's disease.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(24), pp. e2210719120. 2023 Jun 06. Hirase HNedergaard M Locomotion Induces Fundamentally Different Patterns of Ca2+ Signaling in Astrocytes and Neurons.; Function (Oxford, England); Vol 4(4), pp. zqad028. 2023 Jun 05. Holstein-Rønsbo SGan YGiannetto MJRasmussen MKSigurdsson BBeinlich FRMRose LUntiet VHablitz LMKelley DHNedergaard M Glymphatic influx and clearance are accelerated by neurovascular coupling.; Nature neuroscience. 2023 Jun 01. Raizen DMMullington JAnaclet CClarke GCritchley HDantzer RDavis RDrew KLFessel JFuller PMGibson EMHarrington MLipkin WIKlerman EBKlimas NKomaroff ALKoroshetz WKrupp LKuppuswamy ALasselin JLewis LDMagistretti PJMatos HYMiaskowski CMiller AHNath ANedergaard MOpp MRRitchie MDRogulja DRolls ASalamone JDSaper CWhittemore VWylie GYounger JZee PCHeller HC Beyond the Symptom: The Biology of Fatigue.; Sleep. 2023 May 24. Stogsdill JAHarwell CCGoldman SA Astrocytes as master modulators of neural networks: Synaptic functions and disease-associated dysfunction of astrocytes.; Annals of the New York Academy of Sciences. 2023 May 23. Agarwal NLewis LDHirschler LRivera LRNaganawa SLevendovszky SRRingstad GKlarica MWardlaw JIadecola CHawkes CCarare ROWells JBakker ENTPKurtcuoglu VBilston LNedergaard MMori YStoodley MAlperin Nde Leon Mvan Osch MJP Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome.; Journal of magnetic resonance imaging : JMRI. 2023 May 04. Kjaerby CAndersen MHauglund NUntiet VDall CDing FHirase HNedergaard M Reply to: 'Do all norepinephrine surges disrupt sleep?'.; Nature neuroscience. 2023 Apr 20. Untiet VBeinlich FRMKusk PKang NLadrón-de-Guevara ASong WKjaerby CAndersen MHauglund NBojarowska ZSigurdsson BDeng SHirase HPetersen NCVerkhratsky ANedergaard M Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice.; Nature communications; Vol 14(1), pp. 1871. 2023 Apr 04. Parka AVolbracht CHall BBastlund JFNedergaard MLaursen BBotta PSotty F Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model.; Journal of Alzheimer's disease : JAD. 2023 Mar 31. Ge GRRolland JPSong WNedergaard MParker KJ Fluid compartments influence elastography of the aging mouse brain.; Physics in medicine and biology. 2023 Mar 30. Boster KASCai SLadrón-de-Guevara ASun JZheng XDu TThomas JHNedergaard MKarniadakis GEKelley DH Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(14), pp. e2217744120. 2023 Mar 29. Delle CCankar NDigebjerg Holgersson CHvorup Knudsen HSchiøler Nielsen EKjaerby CMori YNedergaard MWeikop P Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice.; Scientific reports; Vol 13(1), pp. 4137. 2023 Mar 13. Khakh BSGoldman SA Astrocytic contributions to Huntington's disease pathophysiology.; Annals of the New York Academy of Sciences; Vol 1522(1), pp. 42-59. 2023 Mar 02. Sigurdsson BHauglund NLLilius TOMogensen FLMortensen KNBeschorner NKlinger LBærentzen SLRosenholm MPShalgunov VHerth MMori YNedergaard M A SPECT-based method for dynamic imaging of the glymphatic system in rats.; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023 Feb 21. Raicevic NForer JMLadron-de-Guevara ADu TNedergaard MKelley DHBoster KAS Sizes and Shapes of Perivascular Spaces Surrounding Murine Pial Arteries.; Research square. 2023 Feb 17. Gomolka RSHablitz LMMestre HGiannetto MDu THauglund NLXie LPeng WMartinez PMNedergaard MMori Y Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation.; eLife; Vol 12. 2023 Feb 09. Plá VBitsika SGiannetto MLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Structural characterization of SLYM - a 4th meningeal membrane.; Research square. 2023 Jan 31. Lilius TOMortensen KNDeville CLohela TJStæger FFSigurdsson BFiordaliso EMRosenholm MKamphuis CBeekman FJJensen AINedergaard M Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles.; Journal of controlled release : official journal of the Controlled Release Society. 2023 Jan 30. Plá VBitsika SGiannetto MLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Structural characterization of SLYM - a 4 th meningeal membrane.; bioRxiv : the preprint server for biology. 2023 Jan 28. Nasu YAggarwal ALe GNTVo CTKambe YWang XBeinlich FRMLee ABRam TRWang FGorzo KAKamijo YBoisvert MNishinami SKawamura GOzawa TToda HGordon GRGe SHirase HNedergaard MPaquet MEDrobizhev MPodgorski KCampbell RE Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging.; Nature communications; Vol 14(1), pp. 6598. 2023 Jan 27. Esmail TNedergaard MBeinlich FRM Protocol to study molecule exchange between venous blood and CSF in live mice using transcranial bioluminescence imaging.; STAR protocols; Vol 4(4), pp. 102652. 2023 Jan 25. Parka ADegel CDreyer JRichter UHall BBastlund JFLaursen BNedergaard MSotty FBotta P Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model.; Neurobiology of disease; Vol 178, pp. 106012. 2023 Jan 23. Hussain RTithof JWang WCheetham-West ASong WPeng WSigurdsson BKim DSun QPeng SPlá VKelley DHHirase HCastorena-Gonzalez JAWeikop PGoldman SADavis MJNedergaard M Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema.; Nature. 2023 Jan 15. Plá VBitsika SGiannetto MJLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Structural characterization of SLYM-a 4th meningeal membrane.; Fluids and barriers of the CNS; Vol 20(1), pp. 93. 2023 Jan 14. Wang XDelle CPeng WPlá VGiannetto MKusk PSigurdsson BSakurai SSweeney ASun QDu TLibby RTNedergaard M Age- and glaucoma-induced changes to the ocular glymphatic system.; Neurobiology of disease. 2023 Jan 11. Møllgård KBeinlich FRMKusk PMiyakoshi LMDelle CPlá VHauglund NLEsmail TRasmussen MKGomolka RSMori YNedergaard M A mesothelium divides the subarachnoid space into functional compartments.; Science (New York, N.Y.); Vol 379(6627), pp. 84-88. 2023 Jan 05. Ge GRSong WNedergaard MRolland JPParker KJ Corrigendum: Theory of sleep/wake cycles affecting brain elastography (2022Phys. Med. Biol.67225013).; Physics in medicine and biology; Vol 68(21). 2023 Jan 02. Helakari HJärvelä MVäyrynen TTuunanen JPiispala JKallio MEbrahimi SMPoltojainen VKananen JElabasy AHuotari NRaitamaa LTuovinen TKorhonen VNedergaard MKiviniemi V Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations.; Frontiers in neuroscience; Vol 17, pp. 1275184. 2023 Jan 01. Plá VNedergaard M An unnoticed player overseeing CSF flux.; Nature cardiovascular research; Vol 1(12), pp. 1114-1115. 2022 Dec. Lilius TORosenholm MKlinger LMortensen KNSigurdsson BMogensen FLHauglund NLNielsen MSNRantamäki TNedergaard M SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline.; iScience; Vol 25(10), pp. 105250. 2022 Sep 29. Lopes van den Broek SShalgunov VGarcía Vázquez RBeschorner NBidesi NSRNedergaard MKnudsen GMSehlin DSyvänen SHerth MM Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible?; Pharmaceuticals (Basel, Switzerland); Vol 15(10). 2022 Sep 27. Lopes van den Broek SSehlin DAndersen JVAldana BIBeschörner NNedergaard MKnudsen GMSyvänen SHerth MM The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier.; Frontiers in nuclear medicine (Lausanne, Switzerland); Vol 2, pp. 1001722. 2022 Sep 23. Alvarado AGTessema KMuthukrishnan SDSober MKawaguchi RLaks DRBhaduri ASwarup VNathanson DAGeschwind DHGoldman SAKornblum HI Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.; Cancer research communications; Vol 2(9), pp. 1049-1060. 2022 Sep 22. Wang XDelle CAsiminas AAkther SVittani MBrøgger PKusk PVo CTRadovanovic TKonno AHirai HFukuda MWeikop PGoldman SANedergaard MHirase H Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation.; Cell reports methods; Vol 2(10), pp. 100302. 2022 Sep 21. Carlsen EMMNedergaard MRasmussen RN Versatile treadmill system for measuring locomotion and neural activity in head-fixed mice.; STAR protocols; Vol 3(4), pp. 101701. 2022 Sep 14. Wu SYWen YSerre NBCLaursen CCHDietz AGTaylor BRDrobizhev MMolina RSAggarwal ARancic VBecker MBallanyi KPodgorski KHirase HNedergaard MFendrych MLemieux MJEberl DFKay ARCampbell REShen Y A sensitive and specific genetically encoded potassium ion biosensor for in vivo applications across the tree of life.; PLoS biology; Vol 20(9), pp. e3001772. 2022 Sep 06. Benraiss AMariani JNTate AMadsen PMClark KMWelle KASolly RCapellano LBentley KChandler-Militello DGoldman SA A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice.; Cell reports; Vol 40(9), pp. 111291. 2022 Aug 30. Giannetto MJHablitz LM Reading to the end(foot): translational readthrough of AQP4 increases amyloid-β clearance.; Brain : a journal of neurology. 2022 Aug 25. Bohr THjorth PGHolst SCHrabětová SKiviniemi VLilius TLundgaard IMardal KAMartens EAMori YNägerl UVNicholson CTannenbaum AThomas JHTithof JBenveniste HIliff JJKelley DHNedergaard M The glymphatic system: Current understanding and modeling.; iScience; Vol 25(9), pp. 104987. 2022 Aug 20. Lohela TJLilius TONedergaard M The glymphatic system: implications for drugs for central nervous system diseases.; Nature reviews. Drug discovery. 2022 Aug 10. Zubair HShamas SUllah HNabi GHuma TUllah RHussain RShahab M Morphometric and Myelin Basic Protein Expression Changes in Arcuate Nucleus Kisspeptin Neurons Underlie Activation of Hypothalamic Pituitary Gonadal-axis in Monkeys (Macaca Mulatta) during the Breeding Season.; Endocrine research; Vol 47(3-4), pp. 113-123. 2022 Jul 22. Wostyn PMader THGibson CRNedergaard M The effect of long-duration spaceflight on perivascular spaces within the brain.; Proceedings of the National Academy of Sciences of the United States of America; Vol 119(32), pp. e2207724119. 2022 Jul 18. Kjaerby CAndersen MHauglund NUntiet VDall CSigurdsson BDing FFeng JLi YWeikop PHirase HNedergaard M Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine.; Nature neuroscience. 2022 Jul 07. Mestre HVerma NGreene TDLin LALadron-de-Guevara ASweeney AMLiu GThomas VKGalloway CAde Mesy Bentley KLNedergaard MMehta RI Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer's disease.; Nature communications; Vol 13(1). 2022 Jul 06. Rosser AEBusse MEGray WPBadin RAPerrier ALWheelock VCozzi EMartin UPSalado-Manzano CMills LJDrew CGoldman SACanals JMThompson LM Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder.; Brain : a journal of neurology; Vol 145(5). 2022 Jun 03. Tithof JBoster KASBork PARNedergaard MThomas JHKelley DH A network model of glymphatic flow under different experimentally-motivated parametric scenarios.; iScience; Vol 25(5). 2022 May 20. Kananen JJärvelä MKorhonen VTuovinen THuotari NRaitamaa LHelakari HVäyrynen TRaatikainen VNedergaard MAnsakorpi HJacobs JLeVan PKiviniemi V Increased interictal synchronicity of respiratory related brain pulsations in epilepsy.; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2022 May 14. Ladrón-de-Guevara AShang JKNedergaard MKelley DH Perivascular pumping in the mouse brain: Improved boundary conditions reconcile theory, simulation, and experiment.; Journal of theoretical biology. 2022 Mar 23. Monai HKoketsu SShinohara YUeki TKusk PHauglund NLSamson AJNedergaard MHirase H Author Correction: Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.; Scientific reports; Vol 12(1). 2022 Mar 18. Beaman EEBonde ANUlv Larsen SMOzenne BLohela TJNedergaard MGíslason GHKnudsen GMHolst SC Blood-brain barrier permeable β-blockers linked to lower risk of Alzheimer's disease in hypertension.; Brain : a journal of neurology. 2022 Feb 23. Helakari HKorhonen VHolst SCPiispala JKallio MVäyrynen THuotari NRaitamaa LTuunanen JKananen JJärvelä MTuovinen TRaatikainen VBorchardt VKinnunen HNedergaard MKiviniemi V Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations.; The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022 Feb 07. Ge GRSong WNedergaard MRolland JPParker KJ Theory of sleep/wake cycles affecting brain elastography.; Physics in medicine and biology. 2022 Jan 27. Feng WZhang YDing SChen SWang TWang ZZou YSheng CChen YPang YMarshall CShi JNedergaard MLi QXiao M B lymphocytes ameliorate Alzheimer's disease-like neuropathology via interleukin-35.; Brain, behavior, and immunity; Vol 108, pp. 16-31. 2022 Jan 24. Persson NDÅUusalo PNedergaard MLohela TJLilius TO Could dexmedetomidine be repurposed as a glymphatic enhancer?; Trends in pharmacological sciences. 2022 Jan 21. Muthukrishnan SDKawaguchi RNair PPrasad RQin YJohnson MWang QVanderVeer-Harris NPham AAlvarado AGCondro MCGao FGau RCastro MGLowenstein PRDeb AHinman JDPajonk FBurns TCGoldman SAGeschwind DHKornblum HI P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells.; Nature communications; Vol 13(1), pp. 6202. 2022 Jan 19. Ghochani YMuthukrishnan SDSohrabi AKawaguchi RCondro MCBastola SGao FQin YMottahedeh JIruela-Arispe MLRao NLaks DRLiau LMMathern GWGoldman SACarmichael STNakano ICoppola GSeidlits SKKornblum HI A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration.; Cell reports; Vol 41(3), pp. 111511. 2022 Jan 18. Liu GLadrón-de-Guevara AIzhiman YNedergaard MDu T Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies.; Fluids and barriers of the CNS; Vol 19(1), pp. 101. 2022 Jan 15. Osorio MJMariani JNZou LSchanz SJHeffernan KCornwell AGoldman SA Glial progenitor cells of the adult human white and grey matter are contextually distinct.; Glia. 2022 Jan 05. Shalgunov VLopes van den Broek SVang Andersen IGarcía Vázquez RRaval NRPalner MMori YSchäfer GHerrmann BMikula HBeschorner NNedergaard MSyvänen SBarz MMoos Knudsen GBattisti UMHerth MM Pretargeted imaging beyond the blood-brain barrier.; RSC medicinal chemistry; Vol 14(3), pp. 444-453. 2022 Jan 02. Wostyn PMader THGibson CRNedergaard M Does Long-Duration Exposure to Microgravity Lead to Dysregulation of the Brain and Ocular Glymphatic Systems?; Eye and brain; Vol 14. 2022. Newell DWNedergaard MAaslid R Physiological Mechanisms and Significance of Intracranial B Waves.; Frontiers in neurology; Vol 13. 2022. Plá VBork PHarnpramukkul AOlveda GLadrón-de-Guevara AGiannetto MHussain RWang WKelley DHablitz LNedergaard M A novel real-time in vivo clearance assay for quantification of glymphatic efflux; Cell Reports. 2022 Jan 01. Martikainen MVAakko-Saksa Pvan den Broek LCassee FRCarare ROChew SDinnyes AGiugno RKanninen KMMalm TMuala ANedergaard MOudin AOyola PPfeiffer TVRönkkö TSaarikoski SSandström TSchins RPFTopinka JYang MZeng XWesterink RHSJalava PI TUBE Project: Transport-Derived Ultrafines and the Brain Effects.; International journal of environmental research and public health; Vol 19(1). 2021 Dec 28. Battistella RKritsilis MMatuskova HHaswell DCheng AXMeissner ANedergaard MLundgaard I Not All Lectins Are Equally Suitable for Labeling Rodent Vasculature.; International journal of molecular sciences; Vol 22(21). 2021 Oct 26. Hablitz LMNedergaard M The glymphatic system.; Current biology : CB; Vol 31(20). 2021 Oct 25. Du TMestre HKress BTLiu GSweeney AMSamson AJRasmussen MKMortensen KNBork PARPeng WOlveda GEBashford LToro ERTithof JKelley DHThomas JHHjorth PGMartens EAMehta RIHirase HMori YNedergaard M Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema.; Brain : a journal of neurology. 2021 Sep 28. Hablitz LMNedergaard M The Glymphatic System: A Novel Component of Fundamental Neurobiology.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 41(37). 2021 Sep 15. Pavan CL R Xavier ARamos MFisher JKritsilis MLinder ABentzer PNedergaard MLundgaard I DNase Treatment Prevents Cerebrospinal Fluid Block in Early Experimental Pneumococcal Meningitis.; Annals of neurology. 2021 Aug 16. Benveniste HNedergaard M Cerebral small vessel disease: A glymphopathy?; Current opinion in neurobiology; Vol 72. 2021 Aug 15. Mogensen FLDelle CNedergaard M The Glymphatic System (En)during Inflammation.; International journal of molecular sciences; Vol 22(14). 2021 Jul 13. Wardlaw JMBenveniste HNedergaard MZlokovic BVCharpak SSmith KJBlack SE Reply to: Rethink the classical view of cerebrospinal fluid production.; Nature reviews. Neurology. 2021 Jul 12. Benraiss AMariani JNOsipovitch MCornwell AWindrem MSVillanueva CBChandler-Militello DGoldman SA Cell-intrinsic glial pathology is conserved across human and murine models of Huntington's disease.; Cell reports; Vol 36(1). 2021 Jul 06. Li JPan LPembroke WGRexach JEGodoy MICondro MCAlvarado AGHarteni MChen YWStiles LChen AYWanner IBYang XGoldman SAGeschwind DHKornblum HIZhang Y Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes.; Nature communications; Vol 12(1). 2021 Jun 25. Park HJJeon JChoi JKim JYKim HSHuh JYGoldman SASong J Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model.; Cell proliferation. 2021 Jun 21. Hyun IClayton EWCong YFujita MGoldman SAHill LRMonserrat NNakauchi HPedersen RARooke HMTakahashi JKnoblich JA ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts.; Stem cell reports; Vol 16(6). 2021 Jun 08. Lovell-Badge RAnthony EBarker RABubela TBrivanlou AHCarpenter MCharo RAClark AClayton ECong YDaley GQFu JFujita MGreenfield AGoldman SAHill LHyun IIsasi RKahn JKato KKim JSKimmelman JKnoblich JAMathews DMontserrat NMosher JMunsie MNakauchi HNaldini LNaughton GNiakan KOgbogu UPedersen RRivron NRooke HRossant JRound JSaitou MSipp DSteffann JSugarman JSurani ATakahashi JTang FTurner LZettler PJZhai X ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.; Stem cell reports. 2021 May 25. Rasmussen MKMestre HNedergaard M Fluid Transport in the Brain.; Physiological reviews. 2021 May 05. Monai HKoketsu SShinohara YUeki TKusk PHauglund NLSamson AJNedergaard MHirase H Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.; Scientific reports; Vol 11(1). 2021 Apr 14. Kim KPLi CBunina DJeong HWGhelman JYoon JShin BPark HHan DWZaugg JBKim JKuhlmann TAdams RHNoh KMGoldman SASchöler HR Donor cell memory confers a metastable state of directly converted cells.; Cell stem cell. 2021 Apr 07. Rajna ZMattila HHuotari NTuovinen TKrüger JHolst SCKorhonen VRemes AMSeppänen THennig JNedergaard MKiviniemi V Cardiovascular brain impulses in Alzheimer's disease.; Brain : a journal of neurology. 2021 Mar 31. Yuste RHawrylycz MAalling NAguilar-Valles AArendt DArmañanzas RAscoli GABielza CBokharaie VBergmann TBBystron ICapogna MChang YClemens Ade Kock CPJDeFelipe JDos Santos SEDunville KFeldmeyer DFiáth RFishell GJFoggetti AGao XGhaderi PGoriounova NAGüntürkün OHagihara KHall VJHelmstaedter MHerculano-Houzel SHilscher MMHirase HHjerling-Leffler JHodge RHuang JHuda RKhodosevich KKiehn OKoch HKuebler ESKühnemund MLarrañaga PLelieveldt BLouth ELLui JHMansvelder HDMarin OMartinez-Trujillo JChameh HMMohapatra ANMunguba HNedergaard MNěmec POfer NPfisterer UGPontes SRedmond WRossier JSanes JRScheuermann RHSerrano-Saiz EStaiger JFSomogyi PTamás GTolias ASTosches MAGarcía MTWozny CWuttke TVLiu YYuan JZeng HLein E Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types.; Nature neuroscience. 2021 Mar 19. Raghunandan ALadron-de-Guevara ATithof JMestre HDu TNedergaard MThomas JHKelley DH Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection.; eLife; Vol 10. 2021 Mar 09. Escartin CGalea ELakatos AO'Callaghan JPPetzold GCSerrano-Pozo ASteinhäuser CVolterra ACarmignoto GAgarwal AAllen NJAraque ABarbeito LBarzilai ABergles DEBonvento GButt AMChen WTCohen-Salmon MCunningham CDeneen BDe Strooper BDíaz-Castro BFarina CFreeman MGallo VGoldman JEGoldman SAGötz MGutiérrez AHaydon PGHeiland DHHol EMHolt MGIino MKastanenka KVKettenmann HKhakh BSKoizumi SLee CJLiddelow SAMacVicar BAMagistretti PMessing AMishra AMolofsky AVMurai KKNorris CMOkada SOliet SHROliveira JFPanatier AParpura VPekna MPekny MPellerin LPerea GPérez-Nievas BGPfrieger FWPoskanzer KEQuintana FJRansohoff RMRiquelme-Perez MRobel SRose CRRothstein JDRouach NRowitch DHSemyanov ASirko SSontheimer HSwanson RAVitorica JWanner IBWood LBWu JZheng BZimmer ERZorec RSofroniew MVVerkhratsky A Reactive astrocyte nomenclature, definitions, and future directions.; Nature neuroscience. 2021 Feb 15. Stanton EHPersson NDÅGomolka RSLilius TSigurðsson BLee HXavier ALRBenveniste HNedergaard MMori Y Mapping of CSF transport using high spatiotemporal resolution dynamic contrast-enhanced MRI in mice: Effect of anesthesia.; Magnetic resonance in medicine. 2021 Jan 11. Goldman SAMariani JNMadsen PM Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic.; Seminars in cell & developmental biology. 2021 Jan 04. Liu GMestre HSweeney AMSun QWeikop PDu TNedergaard M Direct Measurement of Cerebrospinal Fluid Production in Mice.; Cell reports; Vol 33(12). 2020 Dec 22. Tuovinen TKananen JRajna ZLieslehto JKorhonen VRytty RMattila HHuotari NRaitamaa LHelakari HElseoud AAKrüger JLeVan PTervonen OHennig JRemes AMNedergaard MKiviniemi V The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies.; Scientific reports; Vol 10(1). 2020 Dec 09. Yuste RHawrylycz MAalling NAguilar-Valles AArendt DArnedillo RAAscoli GABielza CBokharaie VBergmann TBBystron ICapogna MChang YClemens Ade Kock CPJDeFelipe JDos Santos SEDunville KFeldmeyer DFiáth RFishell GJFoggetti AGao XGhaderi PGoriounova NAGüntürkün OHagihara KHall VJHelmstaedter MHerculano SHilscher MMHirase HHjerling-Leffler JHodge RHuang JHuda RKhodosevich KKiehn OKoch HKuebler ESKühnemund MLarrañaga PLelieveldt BLouth ELLui JHMansvelder HDMarin OMartinez-Trujillo JMoradi Chameh HNath ANedergaard MNěmec POfer NPfisterer UGPontes SRedmond WRossier JSanes JRScheuermann RSerrano-Saiz ESteiger JFSomogyi PTamás GTolias ASTosches MAGarcía MTVieira HMWozny CWuttke TVYong LYuan JZeng HLein E Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types.; Nature neuroscience. 2020 Dec 04. Feng LChao JTian ELi LYe PZhang MChen XCui QSun GZhou TFelix GQin YLi WMeza EDKlein JGhoda LHu WLuo YDang WHsu DGold JGoldman SAMatalon RShi Y Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs.; Advanced science (Weinheim, Baden-Wurttemberg, Germany); Vol 7(23). 2020 Dec. Goldman NHablitz LMMori YNedergaard M The Glymphatic System and Pain.; Medical acupuncture; Vol 32(6). 2020 Dec 01. Min Rivas FLiu JMartell BCDu TMestre HNedergaard MTithof JThomas JHKelley DH Surface periarterial spaces of the mouse brain are open, not porous.; Journal of the Royal Society, Interface; Vol 17(172). 2020 Nov. Nedergaard MGoldman SA Glymphatic failure as a final common pathway to dementia.; Science (New York, N.Y.); Vol 370(6512). 2020 Oct 02. Giannetto MXia MStæger FFMetcalfe TVinitsky HSDang JAMLXavier ALRKress BTNedergaard MHablitz LM Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice.; Scientific reports; Vol 10(1). 2020 Sep 30. Hablitz LMPlá VGiannetto MVinitsky HSStæger FFMetcalfe TNguyen RBenrais ANedergaard M Circadian control of brain glymphatic and lymphatic fluid flow.; Nature communications; Vol 11(1). 2020 Sep 02. Todd WDVenner AAnaclet CBroadhurst RYDe Luca RBandaru SSIssokson LHablitz LMCravetchi OArrigoni ECampbell JNAllen CNOlson DPFuller PM Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations.; Nature communications; Vol 11(1). 2020 Sep 02. Yuste RHawrylycz MAalling NAguilar-Valles AArendt DArnedillo RAAscoli GABielza CBokharaie VBergmann TBBystron ICapogna MChang YClemens Ade Kock CPJDeFelipe JDos Santos SEDunville KFeldmeyer DFiáth RFishell GJFoggetti AGao XGhaderi PGoriounova NAGüntürkün OHagihara KHall VJHelmstaedter MHerculano SHilscher MMHirase HHjerling-Leffler JHodge RHuang JHuda RKhodosevich KKiehn OKoch HKuebler ESKühnemund MLarrañaga PLelieveldt BLouth ELLui JHMansvelder HDMarin OMartinez-Trujillo JMoradi Chameh HNath ANedergaard MNěmec POfer NPfisterer UGPontes SRedmond WRossier JSanes JRScheuermann RSerrano-Saiz ESteiger JFSomogyi PTamás GTolias ASTosches MAGarcía MTVieira HMWozny CWuttke TVYong LYuan JZeng HLein E A community-based transcriptomics classification and nomenclature of neocortical cell types.; Nature neuroscience. 2020 Aug 24. Ng Kee Kwong KCMehta ARNedergaard MChandran S Defining novel functions for cerebrospinal fluid in ALS pathophysiology.; Acta neuropathologica communications; Vol 8(1). 2020 Aug 20. Zeng JDong SLuo ZXie XFu BLi PLiu CYang XChen YWang XLiu ZWu JYan YWang FChen JFZhang JLong GGoldman SALi SZhao ZLiang Q The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis.; Cell stem cell. 2020 Aug 04. Rangroo Thrane VHynnekleiv LWang XThrane ASKrohn JNedergaard M Twists and turns of ocular glymphatic clearance - new study reveals surprising findings in glaucoma.; Acta ophthalmologica. 2020 Jul 24. Stæger FFMortensen KNNielsen MSNSigurdsson BKaufmann LKHirase HNedergaard M A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices.; Scientific data; Vol 7(1). 2020 Jul 13. Goldman SA Glial evolution as a determinant of human behavior and its disorders.; Annals of the New York Academy of Sciences; Vol 1471(1). 2020 Jul. Windrem MSSchanz SJZou LChandler-Militello DKuypers NJNedergaard MLu YMariani JNGoldman SA Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain.; Cell reports; Vol 31(7). 2020 May 19. Mestre HMori YNedergaard M The Brain's Glymphatic System: Current Controversies.; Trends in neurosciences. 2020 May 15. Rasmussen RO'Donnell JDing FNedergaard M Interstitial ions: A key regulator of state-dependent neural activity?; Progress in neurobiology. 2020 May 12. Ulv Larsen SMLandolt HPBerger WNedergaard MKnudsen GMHolst SC Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep.; PLoS biology; Vol 18(5). 2020 May. Ghoumari AMAbi Ghanem CAsbelaoui NSchumacher MHussain R Roles of Progesterone, Testosterone and Their Nuclear Receptors in Central Nervous System Myelination and Remyelination.; International journal of molecular sciences; Vol 21(9). 2020 Apr 30. Viggiano DWagner CAMartino GNedergaard MZoccali CUnwin RCapasso G Mechanisms of cognitive dysfunction in CKD.; Nature reviews. Nephrology. 2020 Mar 31. Wang XLou NEberhardt AYang YKusk PXu QFörstera BPeng SShi MLadrón-de-Guevara ADelle CSigurdsson BXavier ALRErtürk ALibby RTChen LThrane ASNedergaard M An ocular glymphatic clearance system removes β-amyloid from the rodent eye.; Science translational medicine; Vol 12(536). 2020 Mar 25. Hauglund NLKusk PKornum BRNedergaard M Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 40(11). 2020 Mar 11. Karimy JKReeves BCDamisah EDuy PQAntwi PDavid WWang KSchiff SJLimbrick DDAlper SLWarf BCNedergaard MSimard JMKahle KT Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets.; Nature reviews. Neurology. 2020 Mar 09. Koundal SElkin RNadeem SXue YConstantinou SSanggaard SLiu XMonte BXu FNostrand WVNedergaard MLee HWardlaw JBenveniste HTannenbaum A Publisher Correction: Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System.; Scientific reports; Vol 10(1). 2020 Feb 27. Wardlaw JMBenveniste HNedergaard MZlokovic BVMestre HLee HDoubal FNBrown RRamirez JMacIntosh BJTannenbaum ABallerini LRungta RLBoido DSweeney MMontagne ACharpak SJoutel ASmith KJBlack SE Perivascular spaces in the brain: anatomy, physiology and pathology.; Nature reviews. Neurology. 2020 Feb 24. Li QAalling NNFörstera BErtürk ANedergaard MMøllgård KXavier ALR Aquaporin 1 and the Na+/K+/2Cl- cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system.; Fluids and barriers of the CNS; Vol 17(1). 2020 Feb 11. Koundal SElkin RNadeem SXue YConstantinou SSanggaard SLiu XMonte BXu FVan Nostrand WNedergaard MLee HWardlaw JBenveniste HTannenbaum A Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System.; Scientific reports; Vol 10(1). 2020 Feb 06. Mestre HDu TSweeney AMLiu GSamson AJPeng WMortensen KNStæger FFBork PARBashford LToro ERTithof JKelley DHThomas JHHjorth PGMartens EAMehta RISolis OBlinder PKleinfeld DHirase HMori YNedergaard M Cerebrospinal fluid influx drives acute ischemic tissue swelling.; Science (New York, N.Y.). 2020 Jan 30. Reeves BCKarimy JKKundishora AJMestre HCerci HMMatouk CAlper SLLundgaard INedergaard MKahle KT Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus.; Trends in molecular medicine. 2020 Jan 17. Nolbrant SGiacomoni JHoban DBBruzelius ABirtele MChandler-Militello DPereira MOttosson DRGoldman SAParmar M Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons.; Stem cell reports; Vol 15(4). 2020 Jan 13. Kananen JHelakari HKorhonen VHuotari NJärvelä MRaitamaa LRaatikainen VRajna ZTuovinen TNedergaard MJacobs JLeVan PAnsakorpi HKiviniemi V Respiratory-related brain pulsations are increased in epilepsy-a two-centre functional MRI study.; Brain communications; Vol 2(2). 2020. Hablitz LMGunesch ANCravetchi OMoldavan MAllen CN Cannabinoid Signaling Recruits Astrocytes to Modulate Presynaptic Function in the Suprachiasmatic Nucleus.; eNeuro; Vol 7(1). 2020 Jan. Hussain GWang JRasul AAnwar HQasim MZafar SAziz NRazzaq AHussain Rde Aguilar JGSun T Current Status of Therapeutic Approaches against Peripheral Nerve Injuries: A Detailed Story from Injury to Recovery.; International journal of biological sciences; Vol 16(1), pp. 116-134. 2020 Jan 01. Yoon CQi YMestre HCanavesi CMarola OJCogliati ANedergaard MLibby RTRolland JP Gabor domain optical coherence microscopy combined with laser scanning confocal fluorescence microscopy.; Biomedical optics express; Vol 10(12). 2019 Dec 01. Dietz AGGoldman SANedergaard M Glial cells in schizophrenia: a unified hypothesis.; The lancet. Psychiatry. 2019 Nov 05. Ji RRDonnelly CRNedergaard M Astrocytes in chronic pain and itch.; Nature reviews. Neuroscience; Vol 20(11). 2019 Nov. Nobuta HYang NNg YHMarro SGSabeur KChavali MStockley JHKillilea DWWalter PBZhao CHuie PGoldman SAKriegstein ARFranklin RJMRowitch DHWernig M Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.; Cell stem cell; Vol 25(4). 2019 Oct 03. Grutzendler JNedergaard M Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas.; Trends in neurosciences; Vol 42(8). 2019 Aug. Rasmussen RNicholas EPetersen NCDietz AGXu QSun QNedergaard M Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice.; Cell reports; Vol 28(5). 2019 Jul 30. Sweeney AMPlá VDu TLiu GSun QPeng SPlog BAKress BTWang XMestre HNedergaard M In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy.; Journal of visualized experiments : JoVE. 2019 Jul 29. Zvietcovich FGe GRMestre HGiannetto MNedergaard MRolland JPParker KJ Longitudinal shear waves for elastic characterization of tissues in optical coherence elastography.; Biomedical optics express; Vol 10(7). 2019 Jul 01. Lilius TOBlomqvist KHauglund NLLiu GStæger FFBærentzen SDu TAhlström FBackman JTKalso EARauhala PVNedergaard M Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs.; Journal of controlled release : official journal of the Controlled Release Society; Vol 304. 2019 Jun 28. Smith NABekar LKNedergaard M Astrocytic Endocannabinoids Mediate Hippocampal Transient Heterosynaptic Depression.; Neurochemical research. 2019 Jun 28. Liu ZOsipovitch MBenraiss AHuynh NPTFoti RBates JChandler-Militello DFindling RLTesar PJNedergaard MWindrem MSGoldman SA Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling.; Cell reports; Vol 27(13). 2019 Jun 25. Tithof JKelley DHMestre HNedergaard MThomas JH Hydraulic resistance of periarterial spaces in the brain.; Fluids and barriers of the CNS; Vol 16(1). 2019 Jun 20. Nygaard Mortensen KSanggaard SMestre HLee HKostrikov SXavier ALRGjedde ABenveniste HNedergaard M Impaired Glymphatic Transport in Spontaneously Hypertensive Rats.; The Journal of neuroscience : the official journal of the Society for Neuroscience. 2019 Jun 17. Banach MEdholm ESGonzalez XBenraiss ARobert J Impacts of the MHC class I-like XNC10 and innate-like T cells on tumor tolerance and rejection in the amphibian Xenopus.; Carcinogenesis. 2019 Jun 01. Plog BALou NPierre CACove AKenney HMHitomi EKang HIliff JJZeppenfeld DMNedergaard MVates GE When the air hits your brain: decreased arterial pulsatility after craniectomy leading to impaired glymphatic flow.; Journal of neurosurgery. 2019 May 17. Monai HWang XYahagi KLou NMestre HXu QAbe YYasui MIwai YNedergaard MHirase H Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke.; Proceedings of the National Academy of Sciences of the United States of America. 2019 May 16. Zhou SGiannetto MDeCourcey JKang HKang NLi YZheng SZhao HSimmons WRWei HSBodine DMLow PSNedergaard MWan J Oxygen tension-mediated erythrocyte membrane interactions regulate cerebral capillary hyperemia.; Science advances; Vol 5(5). 2019 May. Munk ASWang WBèchet NBEltanahy AMCheng AXSigurdsson BBenraiss AMäe MAKress BTKelley DHBetsholtz CMøllgård KMeissner ANedergaard MLundgaard I PDGF-B Is Required for Development of the Glymphatic System.; Cell reports; Vol 26(11). 2019 Mar 12. Cai RPan CGhasemigharagoz ATodorov MIFörstera BZhao SBhatia HSParra-Damas AMrowka LTheodorou DRempfler MXavier ALRKress BTBenakis CSteinke HLiebscher SBechmann ILiesz AMenze BKerschensteiner MNedergaard MErtürk A Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections.; Nature neuroscience; Vol 22(2). 2019 Feb. Hablitz LMVinitsky HSSun QStæger FFSigurdsson BMortensen KNLilius TONedergaard M Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia.; Science advances; Vol 5(2). 2019 Feb. Koundal SLiu XSanggaard SMortensen KWardlaw JNedergaard MBenveniste HLee H Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI.; Neuroscience; Vol 404. 2019 Jan 26. Osipovitch MAsenjo Martinez AMariani JNCornwell ADhaliwal SZou LChandler-Militello DWang SLi XBenraiss SJAgate RLampp ABenraiss AWindrem MSGoldman SA Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation.; Cell stem cell; Vol 24(1). 2019 Jan 03. Verkhratsky ANedergaard MSteardo LLi B Editorial: Sleep and Mood Disorders.; Frontiers in psychiatry; Vol 10. 2019. Mariani JNZou LGoldman SA Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease.; Methods in molecular biology (Clifton, N.J.); Vol 1936. 2019. Ramos MBurdon Bechet NBattistella RPavan CXavier ALRNedergaard MLundgaard I Cisterna Magna Injection in Rats to Study Glymphatic Function.; Methods in molecular biology (Clifton, N.J.); Vol 1938. 2019. Sweeney MDMontagne ASagare APNation DASchneider LSChui HCHarrington MGPa JLaw MWang DJJJacobs REDoubal FNRamirez JBlack SENedergaard MBenveniste HDichgans MIadecola CLove SBath PMMarkus HSSalman RAAllan SMQuinn TJKalaria RNWerring DJCarare ROTouyz RMWilliams SCRMoskowitz MAKatusic ZSLutz SELazarov OMinshall RDRehman JDavis TPWellington CLGonzález HMYuan CLockhart SNHughes TMChen CLHSachdev PO'Brien JTSkoog IPantoni LGustafson DRBiessels GJWallin ASmith EEMok VWong APassmore PBarkof FMuller MBreteler MMBRomán GCHamel ESeshadri SGottesman RFvan Buchem MAArvanitakis ZSchneider JADrewes LRHachinski VFinch CEToga AWWardlaw JMZlokovic BV Vascular dysfunction-The disregarded partner of Alzheimer's disease.; Alzheimer's & dementia : the journal of the Alzheimer's Association; Vol 15(1). 2019 Jan. DiNuzzo MWalls ABÖz GSeaquist ERWaagepetersen HSBak LKNedergaard MSchousboe A State-Dependent Changes in Brain Glycogen Metabolism.; Advances in neurobiology; Vol 23. 2019. Wang MQin CLuo XWang JWang XXie MHu JCao JHu TGoldman SANedergaard MWang W Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease.; Theranostics; Vol 9(15). 2019. Mestre HHablitz LMXavier ALFeng WZou WPu TMonai HMurlidharan GCastellanos Rivera RMSimon MJPike MMPlá VDu TKress BTWang XPlog BAThrane ASLundgaard IAbe YYasui MThomas JHXiao MHirase HAsokan AIliff JJNedergaard M Aquaporin-4-dependent glymphatic solute transport in the rodent brain.; eLife; Vol 7. 2018 Dec 18. Plog BAMestre HOlveda GESweeney AMKenney HMCove ADholakia KYTithof JNevins TDLundgaard IDu TKelley DHNedergaard M Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain.; JCI insight; Vol 3(23). 2018 Dec 06. Mestre HTithof JDu TSong WPeng WSweeney AMOlveda GThomas JHNedergaard MKelley DH Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension.; Nature communications; Vol 9(1). 2018 Nov 19.