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URMC / Emergency Preparedness Coalition / COVID-19 POD/Vaccinator Resources and Training / NYS Immunization Information System (NYSIIS)


NYS Immunization Information System (NYSIIS)

New York State Immunization Information System - Mass Vaccination Module

The Mass Vaccination feature in NYSIIS allows users to build a roster list of patients and record their immunizations simultaneously.  This expedites the process of entering immunizations into patient records.  The Mass Vaccination module includes the ability to search for existing patients and the ability to add patients to NYSIIS if they are not yet in the system.  It also allows users to create their patient roster manually or by uploading a CSV file.

The Mass Vaccination module will work hand in hand with the COVID19 pandemic vaccination event.  When recording immunizations via the Mass Vaccination module, users will have the ability to assign the priority group to the selected patients when recording immunizations.

NYSIIS Mass Vaccination Module Use for COVID19 Vaccine
Accessing NYSIIS on NYSDOH Health Commerce System
NYSIIS Vaccine Check Quick Guide
Ordering COVID-19 vaccine in the New York State Immunization Information System

NYSIIS - General Training

General training options/methods exist for NYSIIS can be found HERE

Prebooking COVID19 Vaccine in NYSIIS
NYSIIS Advanced Reports
NYSIIS Reports Only User Training
NYSIIS Standard User Training
NYSIIS Administrative User Training
User Manual – Version 6.1.1 (Revised 1/2018) (PDF)

NYSIIS Questions and Point of Contact

Access to the New York State Immunization Information System (NYSIIS) application must be granted by the NYSIIS Administrative user of your organization. If you do not know who that is, contact:
NYSIIS Help Desk at (866) 389-0371 or

NYSIIS Team at: