Does this test have other names?
What is this test?
This is a test to measure how much erythropoietin (EPO) you have in your blood. EPO
is a hormone that your kidney makes to trigger your bone marrow to make red blood
cells. A normal EPO level means that your body can make healthy red blood cells.
Healthy oxygen levels are linked to having enough red blood cells. For this reason,
EPO levels usually rise when your body isn't getting enough oxygen.
Why do I need this test?
You may need this test if other tests have shown that you have anemia and your healthcare
provider wants to figure out what kind of anemia you have. He or she might also order
this test to help find out whether your kidneys are making a normal amount of EPO. A
level of EPO that’s higher than normal may mean you have a kidney tumor.
If you are a professional cyclist, long-distance runner, or other professional athlete,
you may be asked to take this test. It's sometimes used to find out whether athletes
have been violating anti-doping laws. EPO is used illegally by some athletes to improve
What other tests might I have along with this test?
Because EPO plays a key role in the making of red blood cells, your healthcare provider may
order other blood tests. These include a complete blood count, or CBC. Your provider
may also order other tests for anemia. These could include tests for iron levels,
total iron binding capacity level, ferritin levels, and reticulocyte counts.
What do my test results mean?
Test results may vary depending on your age, gender, health history, the method used
for the test, and other things. Your test results may not mean you have a problem.
Ask your healthcare provider what your test results mean for you.
The normal range for EPO levels can vary from 3.7 to 36 international units per liter
(IU/L). Higher-than-normal levels may mean you have anemia. In severe cases of anemia,
EPO levels in the blood may be a thousand times higher than normal.
Unusually low levels may be because of polycythemia vera. This is a bone marrow disorder
that causes your body to make too many red blood cells. Low EPO levels may also mean
you have kidney disease.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Ask your your healthcare provider about what might affect your results. Donating blood
can raise the EPO level in your blood. Pregnancy and certain medicines can also affect
How do I get ready for this test?
You don't need to prepare for this test. Be sure your healthcare provider knows about
all medicines, herbs, vitamins, and supplements you are taking. This includes medicines
that don't need a prescription and any illicit drugs you may use.