Fish and Shellfish Poisoning
At certain times of the year, various species of fish and shellfish contain poisonous
biotoxins, even if well cooked. The CDC says it is an under-recognized risk for travelers,
specifically in the tropics and subtropics.
Certain fish can cause ciguatera fish poisoning. These include:
The CDC recommends never eating moray eel or barracuda. Other types of fish that may
contain the toxin at unpredictable times include sea bass and a wide range of tropical
reef and warm-water fish. Fish containing these toxins do not look, smell, or taste
bad. Cooking, marinating, freezing, or stewing does not destroy the toxin.
The risk of ciguatera poisoning exists in all tropical and subtropical waters of the
West Indies, the Pacific Ocean, and the Indian Ocean, where these reef fish are eaten.
Two other forms of poisoning can happen from naturally occurring toxins in fish:
Where is the risk of ciguatera poisoning the greatest?
Reef fish from the tropical and subtropical waters of the West Indies, the Pacific
Ocean, and the Indian Ocean pose the greatest threat. Cases have been reported in
the U.S. in Hawaii, Guam, Puerto Rico, U.S. Virgin Islands, and Florida. A few isolated
cases of ciguatera poisoning have even been noted along the eastern seaboard of the
More than 400 species of fish, particularly reef fish, are thought to contain the
toxin for ciguatera poisoning.
What are the symptoms of ciguatera poisoning?
Symptoms of ciguatera poisoning often start between a few minutes and 6 hours after
eating the toxic fish. These include a variety of gastrointestinal, neurological,
and cardiovascular problems. Each person may have different symptoms. But these are
the most common symptoms:
In more severe cases, you may suffer muscle pains, dizziness, and sensations of temperature
reversal, where hot things seem cold and cold things seem hot. You may also have irregular
heart rhythms and low blood pressure.
These symptoms often go away within several days. But they may last up to 4 weeks. They
may look like other health conditions. Always talk with your healthcare provider for
Treatment for ciguatera poisoning
Treatment for ciguatera poisoning involves easing the symptoms and treating any complications.
There is no specific antidote for the toxin itself. Generally, recovery takes from
several days to several weeks.
What is tetrodotoxin?
Tetrodotoxin is also called pufferfish poisoning or fugu poisoning. It is a much rarer
form of fish poisoning. Yet, it may be very serious. It is almost exclusively linked
to eating the pufferfish from waters of the Indo-Pacific regions. There have also
been several reported cases of poisonings, including deaths, from pufferfish from
the Atlantic Ocean, Gulf of Mexico, and Gulf of California. Pufferfish poisoning is
a continuing problem in Japan.
What are the symptoms of pufferfish poisoning?
Symptoms often start between 20 minutes and 3 hours after eating the poisonous pufferfish.
Each person may have different symptoms. But these are the most common symptoms:
Numbness of lips and tongue
Numbness of face and extremities
Sensations of lightness or floating
Nausea and vomiting
Extensive muscle weakness
Death can happen within 4 to 6 hours of poisoning. It is vital to seek medical care
Treatment for pufferfish poisoning
Treatment for pufferfish poisoning consists of limiting how much of the toxin the
body absorbs. It also involves easing symptoms and treating life-threatening complications.
There is no known antidote for tetrodotoxin.
What is scombrotoxin?
Scombrotoxin is also called scombroid poisoning or histamine poisoning. It happens
after eating fish that have high levels of histamine due to improper food handling.
It is one of the most common forms of fish poisoning in the U.S. and worldwide.
Certain fish have high amounts of histidine. As a result of poor refrigeration or
preservation, bacteria turn the histidine into histamine. This leads to scombroid
poisoning. Contaminated fish may look and taste fresh. But some may taste "peppery,"
"spicy," or "bubbly." The toxin may form even if the fish has been stored at too high
a temperature for only a short time.
This form of fish poisoning happens worldwide in temperate and tropical waters. It
can happen after eating:
What are the symptoms of scombroid poisoning?
Symptoms often start within minutes to an hour after eating affected fish. They typically
last 3 hours. But they can last several days. Each person may have different symptoms.
But the most common symptoms are:
Tingling or burning sensations in the mouth
Rash on the face and upper body
Wheezing or shortness of breath
Drop in blood pressure
Hives and itching of skin
These may look like other health conditions. Many cases of "fish allergy" are actually
scombroid poisoning. Always talk with your healthcare provider for a diagnosis.
Treatment for scombroid poisoning
Treatment for scombroid poisoning is generally not needed. Symptoms often go away
within 12 hours. This poisoning is rarely life-threatening. Treatment could include
antihistamines, such as diphenhydramine and cimetidine.
Specific treatment for all fish and shellfish poisoning is based on:
Your overall health and medical history
Extent of the disease
Your tolerance for specific medicines, procedures, and therapies
Your opinion or preference