Does this test have other names?
AST, aspartate aminotransferase, serum glutamic oxaloacetic transaminase test, SGOT
What is this test?
This blood test is used to diagnose liver damage. Aspartate transaminase (AST) is
an enzyme that is released when your liver or muscles are damaged. Although AST is
found mainly in your liver and heart, AST can also be found in small amounts in other
Why do I need this test?
You may need this test if your healthcare provider believes that your liver is damaged.
You might have this test if you have these symptoms related to liver disease:
Light or clay-colored stool
Yellowing of the skin or eyes (jaundice)
Nausea and vomiting
Lack of appetite or weight loss
Weakness or tiredness (fatigue)
Swelling or pain in the belly
You may also have this test if you have a family history of liver illness or drink
an abnormally large amount of alcohol. You may also have this test if you have a condition
such as diabetes that may cause liver problems or if you take medicines that can affect
What other tests might I have along with this test?
You may also need the alanine aminotransferase (ALT) test. It's commonly used along
with the AST test to look at your liver's function. ALT is an enzyme found in the
liver. High levels of ALT can mean hepatitis. Other tests that check liver function
are alkaline phosphatase, gamma-glutamyl transpeptidase (GGT), and total bilirubin.
What do my test results mean?
Test results may vary depending on your age, gender, health history, the method used
for the test, and other things. Your test results may not mean you have a problem.
Ask your healthcare provider what your test results mean for you.
Results are given in units per liter (units/L). Normal ranges for AST are:
Men: 10 to 40 units/L
Women: 9 to 32 units/L
Women tend to have slightly lower levels than men. Older adults tend to have slightly
higher levels than the normal range for adults.
If you have abnormally high levels of AST, you might have:
Extremely high levels of AST may mean you have a disease such as viral hepatitis,
liver injury from medicines or toxins, or "shock liver." Shock liver is widespread
liver damage caused by lack of oxygen or not enough blood supply.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Test results may be falsely lower if you have diabetic ketoacidosis or severe liver
disease. Many medicines may also affect the results.
How do I get ready for this test?
You don't need to prepare for this test. Tell your healthcare provider about all medicines,
herbs, vitamins, and supplements you are taking. This includes medicines that don't
need a prescription and any illegal drugs you may use.