Does this test have other names?
GGTP, gamma-glutamyl transferase, GGT, Gamma-GT, GTP
What is this test?
This test checks the level of the enzyme gamma-glutamyl transpeptidase (GGT) in your
GGT is found in many organs. The highest levels are in liver cells. This test helps
your healthcare provider look for possible damage to your liver or problems with the
liver ducts or gallbladder. It can also help tell the difference between liver and
bone disease if your results from a blood test called alkaline phosphatase are abnormal.
Why do I need this test?
You may need this test if you have other abnormal liver blood tests or your healthcare
provider thinks that you have liver damage. One symptom of liver damage is jaundice.
This is a yellowish tint to your skin and eyes. You may also need this test to see
if you have liver or bone disease. This test is also used to look for chronic alcohol
What other tests might I have along with this test?
You may have other liver enzyme tests. These include:
Alanine aminotransferase (ALT)
Alkaline phosphatase (ALP)
Aspartate aminotransferase (AST)
Creatine phosphokinase (CPK)
Lactic dehydrogenase (LDH)
Leucine aminopeptidase (LAP)
What do my test results mean?
Test results may vary depending on your age, gender, health history, the method used
for the test, and other things. Your test results may not mean you have a problem.
Ask your healthcare provider what your test results mean for you.
Results are given in international units per liter (IU/L). In general, normal results
8 to 61 IU/L for males
5 to 36 IU/L for females
Normal results for children are like those for adults. A newborn's level is 6 to 7
times higher than an adult's.
Higher than normal test results could be a sign of liver damage from diseases such
as hepatitis, cirrhosis, tumors, or pancreatic cancer. But a higher than normal GGT
level does not tell you the cause of liver disease or damage.
GGT may be higher with diabetes, heart failure, hyperthyroidism, or pancreatitis.
Higher GGT levels also may mean liver damage from heavy, chronic alcohol abuse. GGT
levels that are higher than normal may also signal a viral infection, such as Epstein-Barr.
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle has some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Phenobarbital, phenytoin, and other medicines can increase your GGT levels. Other
medicines such as clofibrate and birth control pills can lower your levels.
How do I get ready for this test?
You may be asked to not eat or drink anything but water for 8 hours before having
this test. Tell your healthcare provider about all medicines, herbs, vitamins, and
supplements you are taking. This includes medicines that don't need a prescription
and any illegal drugs you may use.