Does this test have other names?
HPT, hemoglobin-binding protein, Hp
What is this test?
This test measures the level of a protein in your blood called haptoglobin.
Haptoglobin is made by your liver. It binds to a type of hemoglobin that's made when
red blood cells die, leading to anemia. This haptoglobin-hemoglobin complex is removed
from your body by your liver. If too much hemoglobin is bound to haptoglobin, the
levels of haptoglobin will drop. The level of haptoglobin in your blood helps your
healthcare provider figure out what type of anemia you have.
Why do I need this test?
You may have this test if your healthcare provider suspects that you have anemia,
or a low number of red blood cells. Symptoms of anemia include:
You may also have this test if you have symptoms of liver disease.
What other tests might I have along with this test?
Your healthcare provider may also order other blood tests, including:
Your healthcare provider may also order a direct antiglobulin test if you have had
a blood transfusion and they suspect that you are reacting to the transfusion. Your
healthcare provider may also order tests for indirect bilirubin and lactate dehydrogenase
What do my test results mean?
Test results may vary depending on your age, gender, health history, and other things.
Your test results may be different depending on the lab used. They may not mean you
have a problem. Ask your healthcare provider what your test results mean for you.
Results are given in milligrams per deciliter (mg/dL). Normal results depend on your
age and gender, other diseases or conditions you have, and the method the lab uses
to analyze the test.
In general, a normal value for adults is 40 to 200 mg/dL.
If your levels are lower, it means you may have hemolytic anemia, in which your red
blood cells are prematurely destroyed. An undetectable level is almost always due
to hemolytic anemia. Lower levels could also mean that you have had a reaction to
a blood transfusion or that you have liver disease or infectious mononucleosis.
Levels that are higher than normal may mean that you:
How is this test done?
The test is done with a blood sample. A needle is used to draw blood from a vein in
your arm or hand.
Does this test pose any risks?
Having a blood test with a needle carries some risks. These include bleeding, infection,
bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may
feel a slight sting or pain. Afterward, the site may be sore.
What might affect my test results?
Certain medicines can affect your results. These include androgens (a type of hormone)
How do I get ready for this test?
You don't need to prepare for this test. Be sure your healthcare provider knows about
all medicines, herbs, vitamins, and supplements you are taking. This includes medicines
that don't need a prescription and any illegal drugs you may use.