Histidine is an amino acid most people get from food. It's used in growth, repair
of damaged tissues, and making blood cells. It helps protect nerve cells. It's used
by the body to make histamine. Histidine supplements may help treat eczema.
Amino acids (AAs) are available as single AAs or in AA combinations. They also come
as part of multivitamins, proteins, and food supplements. The forms include tablets,
fluids, and powders.
By eating enough protein in your diet, you get all of the amino acids you need.
There are no conditions that increase how much histidine you need.
Side effects and toxicity
Using a single amino acid supplement may lead to negative nitrogen balance. This can
lessen how well your metabolism works. It can make your kidneys work harder. In children,
single amino acid supplements may cause growth problems.
Single amino acid supplements aren’t advised for people who eat an adequate amount
of protein. You shouldn't take high doses of single amino acids for long periods of
Taking too much histidine may cause psychological issues. It may also lead to mood disorders.
People who are pregnant or breastfeeding shouldn’t use histidine supplements.