anthocyanidin, anthocyanadins, anthocyanin, celphinidin, cyanidin, delphinidin, malvidin,
pelargonidin, peonidin, petunidin
Proanthocyanidins and anthocyanidins are chemical compounds. They give many plants,
especially fruit or flowers, their red, blue, or purple colors. These are considered
cancer-preventing pigments. They were first studied for their importance as plant
pigments. Anthocyanins are responsible for the reds, blues, and purples. The closely
related flavonols and flavones are responsible for the yellow and ivory colors in
Anthocyanidins belong to a group of compounds called polyphenols. These belong to
a subclass called flavonoids.
Food sources of anthocyanidins include red and black grapes. Grape skin contains polyphenols,
including anthocyanins and leucoanthocyanins. Grape seeds contain proanthocyanidins.
Other food sources include red wine, bilberries, cranberries, strawberries, blueberries,
red cabbage, and apple peel. Sources of proanthocyanidins include pine bark, grape
seeds, leaves of the bilberry bush, birch, and ginkgo biloba.
Medically valid uses
Research is being done to look at the health benefits of these compounds. It’s known
that a diet rich in vegetables and fruits reduces the risk for many types of cancer.
It also lowers the risk of other age-related problems.
Please note that this section reports on claims that have not yet been substantiated
Anthocyanidins and proanthocyanidins may protect the heart and cardiovascular system.
They may work as antioxidants and block nitrosamines from forming. They may also protect
healthy cells from their mutagenic effects. They also work with vitamin C to decrease
risk of breast cancer. They also reduce risk of blood clot formation. This may lower
the risk of a heart attack.
There is no set dose for proanthocyanidins. Suggested dosages range from 20–200 mg
per day. The standard dose is 150–200 mg.
Women who are pregnant or breastfeeding should talk to their healthcare providers
before taking any supplements.
Side effects, toxicity, and interactions
There are no known side effects linked with proanthocyanidins. There are also no known
food or drug interactions.