Diagnosing arthritis may be difficult. There are more than 100 different types of
arthritis. Many symptoms are similar among the different conditions affecting the
joints. Arthritis may be generally categorized into the following groups: degenerative
arthritis, inflammatory arthritis, metabolic arthritis, and infectious arthritis.
Osteoarthritis (also known as degenerative arthritis) is the most common type. Rheumatoid
arthritis and gout are 2 other more common types. To make an accurate diagnosis, a healthcare
provider may need to:
Review your health history and current symptoms.
Examine you, with close attention to your joints.
Order lab tests, X-rays, and other imaging tests (such as an ultrasound or MRI).
Remove fluid from a joint (arthrocentesis)
What is involved in reviewing your health history and your current symptoms?
When reviewing your health history, your healthcare provider may ask the following
Have you had any illnesses or injuries that may explain the pain?
Is there a family history of arthritis or other rheumatic diseases?
What medicines are you currently taking?
Your healthcare provider may also ask:
What symptoms are you having? For example, pain, stiffness, trouble with movement,
About your pain:
Where is it?
How long have you had it?
When do you have pain and how long does it last?
Describe your pain (constant, dull, throbbing, stabbing)
How intense is it? (On a scale of 1 to 10, with 1 being no pain, and 10, the worst
What lessens the pain?
What makes it worse?
What is involved in lab testing?
In addition to a complete health history and physical exam, the following are common
Antinuclear antibody. This test measures blood levels of various antibodies, which may
be present in people with some types of arthritis.
Arthrocentesis (also called joint aspiration). This is an exam of joint fluid. A thin
needle is inserted into the joint. Synovial fluid is removed with a syringe and examined
for cell counts, crystal analysis, culture, and other tests.
Complement tests. This test measures the level of complement, a group of proteins
in the blood. It is used to help diagnose and monitor systemic lupus erythematosus
(SLE) and rheumatoid arthritis.
Complete blood count (CBC). Measures the number of white blood cells, red blood cells,
and platelets present in a sample of blood. A low white blood count (leukopenia),
low red blood count (anemia), or low platelet count (thrombocytopenia) are linked
to some forms of arthritis or the medicines to treat them.
Creatinine. A blood test to monitor for underlying kidney disease.
C-reactive protein (CRP). This protein is high or is elevated when there is inflammation
in the body, as in some types of arthritis.
Erythrocyte sedimentation rate (also called ESR or sed rate). This measures how quickly
red blood cells fall to the bottom of a test tube. A high ESR level occurs when there
is inflammation in the body. This occurs in some types of arthritis.
Hematocrit(PCV, packed cell volume). Measures the number of red blood cells present
in a sample of blood. Low levels of red blood cells (anemia) are common in people
with some types of arthritis.
Rheumatoid factor. Checks for an antibody that is present in most people with rheumatoid
Urinalysis. Lab exam of urine to check for kidney disease that may be linked to several
types of arthritis.
Uric acid. High levels of uric acid are linked to gout.
What imaging methods may be used to diagnose arthritis?
Imaging methods may give your healthcare provider a clearer picture of what is happening
to your joints. Imaging methods may include the following:
X-ray. X-rays may show joint changes and bone damage found in some types of arthritis.
Other imaging tests may also be done.
Ultrasound. Ultrasound uses sound waves (not radiation) to see the quality of synovial
tissue, tendons, ligaments, and bones.
MRI. MRI images are more detailed than X-rays. They may show damage to joints, including
muscles, ligaments, and cartilage.
Arthroscopy. This procedure uses a thin tube containing a light and camera (arthroscope)
to look inside the joint. The arthroscope is inserted into the joint through a small
cut or incision. Images of the inside of the joint are projected onto a screen. It
is used to evaluate any degenerative or arthritic changes in the joint, to detect
bone diseases and tumors, to figure out the cause of bone pain and inflammation, and
to treat certain conditions.