What is actinic keratosis?
Actinic keratosis (AK) is a rough, scaly spot or bump on sun-exposed skin. Most people
have more than one AK.
AK is the most common precancer of the skin. Over time, it can develop into squamous
cell skin cancer. Because of this, actinic keratoses (AKs) are often treated. If they’re
found and treated early, they don’t have the chance to develop into skin cancer.
What causes actinic keratosis?
Ultraviolet (UV) rays from the sun and from tanning beds cause almost all AKs. Damage
to the skin from UV rays builds up over time. This means that even short-term exposure
to sun on a regular basis can build up over a lifetime and raise the risk for AKs.
Who is at risk for actinic keratosis?
A risk factor is anything that may increase your chance of having a disease. Some
risk factors may not be in your control. But others may be things you can change.
You are more at risk for AKs if you:
Have pale skin, blonde or red hair, and eyes that are blue, green, or gray
Have skin that burns or gets freckles when you’re in the sun
Have been exposed to UV rays without protection
Are older than age 40
Live in a place that gets intense sunlight all year
Use tanning beds or lamps
Have a weakened immune system from chemotherapy, AIDS, or an organ transplant
Have a rare condition that makes your skin very sensitive to UV rays, such as albinism
or xeroderma pigmentosum (XP)
Work outdoors or spend a lot of time in direct sunlight
What are the symptoms of actinic keratosis?
AKs develop slowly in the top layer of skin. They mostly start on skin that’s often
exposed to and damaged by the sun. This includes the face, ears, bald scalp, neck,
backs of hands and forearms, and lips. AKs tend to be flat spots on the skin of the
head and neck. But they appear as bumps on the arms and hands.
The base of an AK may be light or dark, tan, pink, red, or a combination of these.
Or it may be the same color as the skin and a change you feel rather than see. The
scale or crust may be horny, dry, and rough. In some cases, the spot may itch or have
a prickly or sore feeling.
Sometimes the spots come and go, often coming back after sun exposure. Often you will
have more than 1 AK.
AKs that develop on the lip are called actinic cheilitis. They can cause the lips
to crack and feel scaly, dry, and rough.
How is actinic keratosis diagnosed?
AKs are often diagnosed when a person sees a healthcare provider about a skin change
they’ve noticed. The provider will look at and feel the changed skin. The provider
will ask about your health history and do a physical exam. All your skin may be checked,
You may be sent to a dermatologist. This is a healthcare provider with special training
to treat skin problems. A special light, magnifying lens, or camera may be used to
get a very close look at the changed skin or lump.
A healthcare provider can often diagnose a AK by looking at and feeling the area on
your skin. But sometimes AK can be hard to tell apart from skin cancer. You may need
a biopsy. This is when small pieces of tissue are taken from the spot. These samples
can be removed with a small blade or scalpel and examined under a microscope to rule
How is actinic keratosis treated?
Treatment for AK aims to remove or destroy the spot and limit scarring as much as
possible. It may include:
Cryotherapy. This treatment freezes spots that can be seen on the skin. This is the treatment
most often used.
Topical chemotherapy. These medicines are put right onto the skin to destroy the affected cells.
Chemical peels. Strong chemicals are used to destroy the top layers of the skin where the spot started.
Laser surgery. Intense light is used to vaporize thin layers of the spot until it’s all removed.
This can be used to remove spots from the face and scalp, and actinic cheilitis from
Curettage and electrodessication. The spot is scraped away and heat is used to kill any damaged cells that may remain
and stop bleeding.
Photodynamic therapy. Special chemicals are put on the spot and absorbed by the damaged cells. A few hours
later, light is used to turn on the chemical and kill the cells.
Most AKs can be treated and cured. But they may come back. And if you have 1, you
likely will develop others. It’s important to have regular skin exams after treatment.
These exams will help spot new AKs and skin cancer.
What are possible complications of actinic keratosis?
After treatment, the skin will be red and sore. With time, it will heal and new healthy
skin will appear.
Some of the treatments increase sun sensitivity. Talk with your healthcare provider
about this and be very careful to protect your skin from the sun.
It’s important that AK be checked by a healthcare provider and treated, because over
time it may turn into squamous cell skin cancer.
What can I do to prevent actinic keratosis?
You can help prevent AKs by taking these steps:
Apply sunscreen with at least SPF 30 every day.
Don’t use tanning beds or sun lamps.
Do regular skin self-exams to check for changes on your skin. If you notice anything,
talk with your healthcare provider right away.
Key points about actinic keratosis
Actinic keratosis is a rough, scaly spot or bump on sun-exposed skin.
They are caused by UV damage to the skin.
People are more at risk for AKs if they have pale skin, blonde or red hair, or eyes
that are blue, green, or gray.
A skin exam and sometimes a biopsy are needed to diagnose this skin problem.
AKs are often treated, because over time they might turn into skin cancer.
Treatments include creams, cryotherapy, and laser surgery.
Tips to help you get the most from a visit to your healthcare provider:
Know the reason for your visit and what you want to happen.
Before your visit, write down questions you want answered.
Bring someone with you to help you ask questions and remember what your provider tells
At the visit, write down the name of a new diagnosis and any new medicines, treatments,
or tests. Also write down any new instructions your provider gives you.
Know why a new medicine or treatment is prescribed and how it will help you. Also
know what the side effects are.
Ask if your condition can be treated in other ways.
Know why a test or procedure is recommended and what the results could mean.
Know what to expect if you do not take the medicine or have the test or procedure.
If you have a follow-up appointment, write down the date, time, and purpose for that
Know how you can contact your provider if you have questions.