Integrative Health Sciences Facility Core
IHSFC Co-Director Dr. Steve Georas attended the EHSC Center Directors Meeting in Iowa City on June 20, 21, together with Center Director Dr. Lawrence, CEC Director Katrina Korfmacher, new center member Dr. Daniel Croft, and Center Member Dr. Irfan Rahman. At a break out session on translational research in environmental health sciences, Dr. Georas shared our experience with the highly successful IHSFC Translational Mini-Pilot Program.
The Integrative Health Sciences Facility Core (IHSFC) facilitates bidirectional translational research in environmental health sciences. The specific objectives of the IHSFC are to:
- Promote translational environmental health sciences research by Center members by fostering new collaborations between basic scientists and clinical researchers
- Provide hands-on assistance in targeted areas of human subjects and translational research
- Support unique translational opportunities provided by the Inhalation, Behavioral Sciences, and Epigenetics and Elemental Analysis Facilities to researchers within and outside the Center
- Develop new technologies to advance Center research
- Provide seed money to support early-stage collaborative translational research for Center members
- Coordinate with CEC to connect translational environmental health research with communities, health care groups, regulatory agencies, and researchers in other disciplines
The IHSFC is directed by Dr. Steve Georas and Dr. Edwin van Wijngaarden , and is overseen by a Steering Committee. The IHSFC is comprised of five components:
Behavioral Sciences Facility
The Behavioral Sciences Facility provides state–of–the–art equipment and expertise necessary for the design and interpretation of human and animal behaviors in order to assess sensory, motor, motivational and cognitive functioning. The facility assists investigators with behavioral assessments, utilizing established procedures and tests, or when necessary, developing new behavioral paradigms. To schedule services, visit the Behavioral Sciences Facility website.
Elemental Analysis Facility
The Elemental Analysis Facility provides researchers with the ability to quantify metals and non-metal elements from a full range of biological matrices and animal tissues, including both laboratory- and environment- derived samples. Investigators are provided consultation on experimental design, sample preparation and data analysis with highly experienced staff. The facility is equipped with a suite of ICP-MS, OES and AAS instrumentation for trace level elemental analyses. To schedule services, visit the Elemental Analysis Facility website.
The mission of the Epigenetics Core Facility is to provide researchers with scientific and technical expertise needed to conduct gene-specific and global DNA methylation analysis. The facility serves as the catalyst for the growing epigenetics community in the Environmental Health Sciences Center, specifically for investigators who are interested in studying the role of DNA methylation in transcriptional regulation or as a biomarker of environmental exposures and human disease. To schedule services, visit the Epigenetics Facility website.
Inhalation Exposure Facility
The Inhalation Exposure Facility provides investigators access to state-of-the-art methodology to generate and monitor particulate, liquid, gaseous, or mixed atmospheres for animal and human inhalation or cell culture exposures. Our experienced staff help ensure that exposures are carefully controlled and dosimetrically relevant to environmental or workplace conditions. To schedule services, visit the Inhalation Exposure Facility website.
Translational Services in Environmental Health Unit
The Translational Services Unit helps Center members interested in conducted translational research by assisting with the conduct of Human Subjects research, supporting the design and conduct of epidemiological studies, providing seed money for early-stage translational research in environmental health sciences, and developing communication tools that translate research findings to potential partners. To schedule a consultation, visit the Translational Services in Environmental Health page for more information.
Steering Committee Members
- Steve N. Georas, M.D. (Co-Director, IHSFC)
- Edwin VanWijngaarden, Ph.D. (Co-Director, IHSFC)
- Deborah A. Cory-Slechta, Ph.D. (Director, Behavioral Sciences Facility)
- Martha Susiarjo, Ph.D. (Director, Epigenetics Facility)
- Alison Elder, Ph.D. (Director, Inhalation Exposure Facility)
- Matthew Rand, Ph.D. (Director, Elemental Analysis Facility)