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URMC / Environmental Medicine / Lake Ontario MicroPlastics Center / Research / Environmental microplastic particles

Investigating environmental microplastic particles and pollutant interactions 

Project Team

Lisa DeLouise, PhD; Alison Elder, PhD; David Chalupa, MS; Alma Avila Oropeza; Anthony Gonzalez; Kaylin Han

Lisa DeLouiseLisa 
DeLouise
Alison EldeAlison 
Elder

Project Description

Our objectives are to improve our understanding of human exposure to environmental microplastics (< 20 mm) in Lake Ontario near shore water and air. We will learn about the human health impacts associated with this exposure. Studies will also reveal how microplastic particles interact with pollutants to modify bioactivity. 

Research Questions

  • How do microplastics interact with persistent organic and metal ion pollutants in the environment and in the body?

Illustration of how microplastics interact with environmental pollutants

Products/Resources

  1. Morgan, S. E., & DeLouise, L. A. (2024). Effects of microplastic interaction with persistent organic pollutants on the activity of the aryl hydrocarbon and estrogen receptors. Chemosphere, 365, 143338. https://doi.org/10.1016/j.chemosphere.2024.143338 
  2. Morgan, S. E., & DeLouise, L. A. (2024). Assessing bioactivity of environmental water samples filtered using nanomembrane technology and mammalian cell lines. Eco-Environment & Health, 3(3), 347-354. https://doi.org/10.1016/j.eehl.2024.05.004 
  3. Morgan, S. E., Romanick, S. S., DeLouise, L., McGrath, J., & Elder, A. (2024). Understanding Human Health Impacts Following Microplastic Exposure Necessitates Standardized Protocols. Current Protocols, 4(7), e1104. https://doi.org/10.1002/cpz1.1104
  4. Madejski, G. R., Ahmad, S. D., Musgrave, J., Flax, J., Madejski, J. G., Rowley, D. A., DeLouise, L. A., Berger, A. J., Knox, W. H., & McGrath, J. L. (2020). Silicon nanomembrane filtration and imaging for the evaluation of microplastic entrainment along a municipal water delivery route. Sustainability, 12(24), 10655. https://doi.org/10.3390/su122410655 
  5. Morgan, S. E., & DeLouise, L. A. (2020). Further studies in translatable model systems are needed to predict the impacts of human microplastic exposure. Open access journal of toxicology, 4(3), 79.