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Spencer Z. Rosero, MD

Meet The Scientist 

SPENCER Z. ROSERO, MDSpencer Z. Rosero, MD

Associate Professor of Cardiology and Director, Cardiology Clinical Research at the University of Rochester School of Medicine and Dentistry Clinical Director, Center for Medical Technology and Innovation at the University of Rochester

Using Lights and Optics in Cancer Immunotherapy

More than six million Americans experience atrial fibrillation (Afib), a condition that causes irregular and often rapid heart rate that commonly causes poor blood flow. “Atrial fibrillation causes changes in body reflexes, such as catching a ball, and can result in individuals having difficulty performing basic tasks, such as walking to get their mail,” says Dr. Spencer Rosero. “It is also associated with stroke and heart failure when left untreated long-term.” 

In addition, only about half of these individuals are aware that they have Afib. Symptoms are sometimes barely noticeable and can fluctuate depending on the individual’s lifestyle. “How do we recognize the less obvious signs of Afib and use them to help prevent the progression of the condition?” asks Rosero. 

In his clinical trial, participants wear a device similar to a fitness tracking wristband that collects data points over a set period of time for 24 hours a day. He then looks at the variances, small or large, and develops a treatment plan with a holistic approach to health that includes diet, exercise, and medication. 

With the multitude of data variables, Rosero hopes to decipher patterns to develop new therapies for Afib patients and gain a detailed understanding of the disease’s progression patterns. Rosero also developed implantable biosensors that test heart rhythm conditions. The sensor integrated living cells with electronics to create a “biological chip” that detected physiologic and chemical changes with faster, improved accuracy. The results, retrieved without invasive testing, allowed for better and timely response and healthier patient outcomes.