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NIR Fluorescence Imaging of Lymphatic Transport Using ICG

Research Question:
Lymphatic transport will be examined using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities in patients with rheumatoid arthritis and healthy volunteers.

Basic Study Information

Purpose:
Healthy volunteers and patients with Rheumatoid Arthritis (RA) in the developmental arm will have a minimum of two study visits to determine the optimal conditions for visualizing lymphatic transport in the upper extremities. Concentrations of 0.1 mg/ml of Indocyanine Green (ICG) will be injected intradermally into the web spaces of the hands in both upper extremities. Multispectral video and still images will be recorded using the MultiSpectral Imaging System (MSImager). An ultrasound of the upper extremities may be performed after the ICG fluorescence is observed. The exam will help identify the location of the lymphatic vessels and nodes in the areas fluoresced.

Location: University of Rochester
Study Reference #: NA2

Lead Researcher (Principal Investigator)

Lead Researcher: Christopher Ritchlin

Study Contact Information

Study Coordinator: Dustina Holt
Phone: (585) 273-5374
Email: Dustina_Holt@urmc.rochester.edu

Additional Study Details

Number of Visits:  2 to 5
Parking:  Free
Transportation Coverage: 
Reimbursement:  Yes

Learn More About These Conditions

More information about Arthritis, Rheumatoid

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