Principal Investigator

Deborah Cory-Slechta, Ph.D. University of Rochester work Box EHSC 601 Elmwood Ave Rochester NY 14642 office: MC 2-6812 p (585) 275-7060

Research Projects

This lab uses multiple techniques to assess the neurotoxicity and behavioral toxicity, associated with environmental chemical exposures, including both operant and spontaneous behaviors, immunohistochemistry, western blotting enzyme linked immunosorbent assays, high-performance liquid chromatography for central neurotransmitter quantification, histology, unbiased stereology, histological imagine analysis, and many others, as means of identifying neurotoxicity of environmental toxicants and non-chemical stressors. Neurotoxicity is examined concomitantly with the assessment of behavioral function. We emphasize behavioral endpoints that can be used across species to facilitate interpretation and direct translation to human populations, This lab examines behaviors across multiple domains including motor function/coordination, response control, fear/anxiety-like behavior, attention, learning, memory, startle response, and social behavior.