URMC / Labs / Anders Lab / Publications Recent Publications Anders MW (2013 Sep). Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria. Mitochondrion. Anders MW (2011 Jun 30). Putting bioactivation reactions to work: Targeting antioxidants to mitochondria. Chemico-biological interactions. Board PGAnders MW (2011 May). Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice. Drug metabolism reviews. Roser KSBrookes PSWojtovich APOlson LPShojaie JParton RLAnders MW (2010 Feb 15). Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria. Bioorganic & medicinal chemistry. Xu LKrenitsky DMSeacat AMButenhoff JLTephly TRAnders MW (2006 Aug). N-glucuronidation of perfluorooctanesulfonamide by human, rat, dog, and monkey liver microsomes and by expressed rat and human UDP-glucuronosyltransferases. Drug metabolism and disposition: the biological fate of chemicals. Starr TBMatanoski GAnders MWAndersen ME (2006 May). Workshop overview: reassessment of the cancer risk of dichloromethane in humans. Toxicological sciences : an official journal of the Society of Toxicology. Fang YYKashkarov UAnders MWBoard PG (2006 May). Polymorphisms in the human glutathione transferase zeta promoter. Pharmacogenetics and genomics. Sheu SSNauduri DAnders MW (2006 Feb). Targeting antioxidants to mitochondria: a new therapeutic direction. Biochimica et biophysica acta. Anders MWRobotham JLSheu SS (2006 Feb). Mitochondria: new drug targets for oxidative stress-induced diseases. Expert opinion on drug metabolism & toxicology. Blackburn ACMatthaei KILim CTaylor MCCappello JYHayes JDAnders MWBoard PG (2006 Feb). Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways. Molecular pharmacology. Anders MW (2005). Formation and toxicity of anesthetic degradation products. Annual review of pharmacology and toxicology. Board PGAnders MW (2005). Human glutathione transferase zeta. Methods in enzymology. Brookes PSYoon YRobotham JLAnders MWSheu SS (2004 Oct). Calcium, ATP, and ROS: a mitochondrial love-hate triangle. American journal of physiology. Cell physiology. Anders MW (2004 Oct). Glutathione-dependent bioactivation of haloalkanes and haloalkenes. Drug metabolism reviews. Lim CEMatthaei KIBlackburn ACDavis RPDahlstrom JEKoina MEAnders MWBoard PG (2004 Aug). Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases. The American journal of pathology. Xu LKrenitsky DMSeacat AMButenhoff JLAnders MW (2004 Jun). Biotransformation of N-ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide by rat liver microsomes, cytosol, and slices and by expressed rat and human cytochromes P450. Chemical research in toxicology. Anderson WBBoard PGAnders MW (2004 May). Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: reaction of glyoxylate with amino acid nucleophiles. Chemical research in toxicology. Lantum HBIyer RAAnders MW (2004 Apr 1). Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities. Biochemical pharmacology. Board PGTaylor MCCoggan MParker MWLantum HBAnders MW (2003 Sep 15). Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique. The Biochemical journal. Lantum HBCornejo JPierce RHAnders MW (2003 Jul). Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency. Toxicological sciences : an official journal of the Society of Toxicology. Jolivette LJAnders MW (2003 Feb). Computational and experimental studies on the distribution of addition and substitution products of the microsomal glutathione transferase 1-catalyzed conjugation of glutathione with fluoroalkenes. Chemical research in toxicology. Lantum HBBaggs RBKrenitsky DMAnders MW (2002 Dec). Nephrotoxicity of chlorofluoroacetic acid in rats. Toxicological sciences : an official journal of the Society of Toxicology. Anderson WBLiebler DCBoard PGAnders MW (2002 Nov). Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta. Chemical research in toxicology. Enomoto AWempe MFTsuchida HShin HJCha SHAnzai NGoto ASakamoto ANiwa TKanai YAnders MWEndou H (2002 Sep 27). Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition. The Journal of biological chemistry. Cooper AJBruschi SAAnders MW (2002 Aug 15). Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism. Biochemical pharmacology. Jolivette LJAnders MW (2002 Aug). Structure-activity relationship for the biotransformation of haloalkenes by rat liver microsomal glutathione transferase 1. Chemical research in toxicology. Lantum HBBoard PGAnders MW (2002 Jul). Kinetics of the biotransformation of maleylacetone and chlorofluoroacetic acid by polymorphic variants of human glutathione transferase zeta (hGSTZ1-1). Chemical research in toxicology. Lantum HBBaggs RBKrenitsky DMBoard PGAnders MW (2002 Jun). Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues. Drug metabolism and disposition: the biological fate of chemicals. Tong ZAnders MW (2002 May). Reactive intermediate formation from the 2-(Fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived cysteine S-conjugate S-[2-(Fluoromethoxy)-1,1,3,3,3-pentafluoropropyl]-L-cysteine in pyridoxal model systems. Chemical research in toxicology. Lantum HBLiebler DCBoard PGAnders MW (2002 May). Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone. Chemical research in toxicology. Bayer TAmberg ABertermann RRusch GMAnders MWDekant W (2002 May). Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa). Chemical research in toxicology. Uchino HKanai YKim DKWempe MFChairoungdua AMorimoto EAnders MWEndou H (2002 Apr). Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Molecular pharmacology. Pombrio JMGiangreco ALi LWempe MFAnders MWSweet DHPritchard JBBallatori N (2001 Nov). Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. Molecular pharmacology. Blackburn ACCoggan MTzeng HFLantum HPolekhina GParker MWAnders MWBoard PG (2001 Nov). GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase. Pharmacogenetics. DeCory HHPiech-Dumas KMSheu SSFederoff HJAnders MW (2001 Oct). Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons. Drug metabolism and disposition: the biological fate of chemicals. Board PGChelvanayagam GJermiin LSTetlow NTzeng HFAnders MWBlackburn AC (2001 Apr). Identification of novel glutathione transferases and polymorphic variants by expressed sequence tag database analysis. Drug metabolism and disposition: the biological fate of chemicals. Chen YCai JAnders MWStevens JLJones DP (2001 Feb 1). Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis. Toxicology and applied pharmacology. Anders MW (2001). Formation and fate of reactive intermediates of haloalkanes, haloalkenes, and alpha-haloacids. Advances in experimental medicine and biology. Lantum HBBoard PGAnders MW (2001). Inactivation of polymorphic variants of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone. Advances in experimental medicine and biology. Luu NCIyer RAAnders MWRidge DP (2000 Jul). Bioactivation mechanisms of haloalkene cysteine S-conjugates modeled by gas-phase, ion-molecule reactions. Chemical research in toxicology. Uttamsingh VBaggs RBKrenitsky DMAnders MW (2000 Jun). Immunohistochemical localization of the acylases that catalyze the deacetylation of N-acetyl-L-cysteine and haloalkene-derived mercapturates. Drug metabolism and disposition: the biological fate of chemicals. Kraus TUttamsingh VAnders MWWolf S (2000 Apr). Porcine kidney microsomal cysteine S-conjugate N-acetyltransferase-catalyzed N-acetylation of haloalkene-derived cysteine S-conjugates. Drug metabolism and disposition: the biological fate of chemicals. Tzeng HFBlackburn ACBoard PGAnders MW (2000 Apr). Polymorphism- and species-dependent inactivation of glutathione transferase zeta by dichloroacetate. Chemical research in toxicology. Morrow PEWitschi HVore MHakkinen PEMacGregor JMacGregor JAnders MWWillhite C (2000 Feb). Profiles in toxicology. Harold Carpenter Hodge (1904-1990). Toxicological sciences : an official journal of the Society of Toxicology. Blackburn ACTzeng HFAnders MWBoard PG (2000 Feb). Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis. Pharmacogenetics. Anderson WBBoard PGGargano BAnders MW (1999 Dec). Inactivation of glutathione transferase zeta by dichloroacetic acid and other fluorine-lacking alpha-haloalkanoic acids. Chemical research in toxicology. Uttamsingh VAnders MW (1999 Oct). Acylase-catalyzed deacetylation of haloalkene-derived mercapturates. Chemical research in toxicology. Wempe MFAnderson WBTzeng HFBoard PGAnders MW (1999 Aug 11). Glutathione transferase zeta-catalyzed biotransformation of deuterated dihaloacetic acids. Biochemical and biophysical research communications. Tu ZAnders MW (1998 Dec 15). Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis. The Biochemical journal. Tong ZBoard PGAnders MW (1998 Nov). Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids. Chemical research in toxicology.