URochester Medicine / Labs / Boutz Lab / Publications

Recent Publications from the Boutz Lab

1. Dillingham CM
2. Cormaty H
3. Morgan EC
4. Tak AI
5. Esgdaille DE
6. Boutz PL
7. Sridharan R
KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells.; iScience; Vol 28(6), pp. 112612. 2025 May 08.
1. Tanu T
2. Cox AM
3. Karlow J
4. Sharma P
5. He X
6. Wu C
7. Babu S
8. Brown J
9. Brown KM
10. Chanock SJ
11. Liu D
12. Zhang T
13. Burns KH
14. Boutz PL
15. Insco ML
Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA.; bioRxiv : the preprint server for biology. 2025 Jan 14.
1. Boutz PL
Putting a finger on histidine methylation.; Genes & development; Vol 37(15-16), pp. 675-677. 2023 Sep 06.
1. Insco ML
2. Abraham BJ
3. Dubbury SJ
4. Kaltheuner IH
5. Dust S
6. Wu C
7. Chen KY
8. Liu D
9. Bellaousov S
10. Cox AM
11. Martin BJE
12. Zhang T
13. Ludwig CG
14. Fabo T
15. Modhurima R
16. Esgdaille DE
17. Henriques T
18. Brown KM
19. Chanock SJ
20. Geyer M
21. Adelman K
22. Sharp PA
23. Young RA
24. Boutz PL
25. Zon LI
Oncogenic CDK13 mutations impede nuclear RNA surveillance.; Science (New York, N.Y.); Vol 380(6642), pp. eabn7625. 2023 Apr 21.
1. Galardi JW
2. Bela VN
3. Jeffery N
4. He X
5. Glasser E
6. Loerch S
7. Jenkins JL
8. Pulvino MJ
9. Boutz PL
10. Kielkopf CL
A UHM - ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.; The Journal of biological chemistry. 2022 Jun 30.
1. Tan ZW
2. Fei G
3. Paulo JA
4. Bellaousov S
5. Martin SES
6. Duveau DY
7. Thomas CJ
8. Gygi SP
9. Boutz PL
10. Walker S
O-GlcNAc regulates gene expression by controlling detained intron splicing.; Nucleic acids research; Vol 48(10), pp. 5656-5669. 2020 Jun 04.
1. Martin SES
2. Tan ZW
3. Itkonen HM
4. Duveau DY
5. Paulo JA
6. Janetzko J
7. Boutz PL
8. Törk L
9. Moss FA
10. Thomas CJ
11. Gygi SP
12. Lazarus MB
13. Walker S
Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.; Journal of the American Chemical Society. 2018 Oct 04.
1. Murphy PA
2. Butty VL
3. Boutz PL
4. Begum S
5. Kimble AL
6. Sharp PA
7. Burge CB
8. Hynes RO
Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow.; eLife; Vol 7. 2018 Jan 02.
1. Dubbury SJ
2. Boutz PL
3. Sharp PA
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation.; Nature; Vol 564(7734). 2018 Jan.
1. Braun CJ
2. Stanciu M
3. Boutz PL
4. Patterson JC
5. Calligaris D
6. Higuchi F
7. Neupane R
8. Fenoglio S
9. Cahill DP
10. Wakimoto H
11. Agar NYR
12. Yaffe MB
13. Sharp PA
14. Hemann MT
15. Lees JA
Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.; Cancer cell; Vol 32(4). 2017 Jan 09.
1. Boutz PL
2. Bhutkar A
3. Sharp PA
Detained introns are a novel, widespread class of post-transcriptionally spliced introns.; Genes & development; Vol 29(1). 2015 Jan 01.
1. Jangi M
2. Boutz PL
3. Paul P
4. Sharp PA
Rbfox2 controls autoregulation in RNA-binding protein networks.; Genes & development; Vol 28(6). 2014 Mar 15.
1. Boutz PL
2. Stoilov P
3. Li Q
4. Lin CH
5. Chawla G
6. Ostrow K
7. Shiue L
8. Ares M
9. Black DL
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.; Genes & development; Vol 21(13). 2007 Jul 01.
1. Boutz PL
2. Chawla G
3. Stoilov P
4. Black DL
MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development.; Genes & development; Vol 21(1). 2007 Jan 01.
1. Underwood JG
2. Boutz PL
3. Dougherty JD
4. Stoilov P
5. Black DL
Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals.; Molecular and cellular biology; Vol 25(22). 2005 Nov.
1. Amir-Ahmady B
2. Boutz PL
3. Markovtsov V
4. Phillips ML
5. Black DL
Exon repression by polypyrimidine tract binding protein.; RNA (New York, N.Y.); Vol 11(5). 2005 May.
1. Biswas SK
2. Boutz PL
3. Nayak DP
Influenza virus nucleoprotein interacts with influenza virus polymerase proteins.; Journal of virology; Vol 72(7), pp. 5493-501. 1998 Jul.
1. Panyutich A
2. Shi J
3. Boutz PL
4. Zhao C
5. Ganz T
Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins.; Infection and immunity; Vol 65(3), pp. 978-85. 1997 Mar.