URMC / Labs / Diekwisch Lab / Publications Recent Publications Lyu HZhou XQian YLiu XGopinathan GPandya MQin CLuan XDiekwisch TGH Long-acting PFI-2 small molecule release and multilayer scaffold design achieve extensive new formation of complex periodontal tissues with unprecedented fidelity.; Biomaterials; Vol 290, pp. 121819. 2022 Sep 22. Gopinathan GDiekwisch TGH Epigenetics and Early Development.; Journal of developmental biology; Vol 10(2). 2022 Jun 16. Pandya MGopinathan GTillberg CWang JLuan XDiekwisch TGH The Hippo Pathway Effectors YAP/TAZ Are Essential for Mineralized Tissue Homeostasis in the Alveolar Bone/Periodontal Complex.; Journal of developmental biology; Vol 10(1). 2022 Mar 01. Shaheen JMudd ABDiekwisch TGHAbramyan J Pseudogenized Amelogenin Reveals Early Tooth Loss in True Toads (Anura: Bufonidae).; Integrative and comparative biology; Vol 61(5), pp. 1933-1945. 2021 Nov 17. Liang TXu QZhang HWang SDiekwisch TGHQin CLu Y Enamel Defects Associated With Dentin Sialophosphoprotein Mutation in Mice.; Frontiers in physiology; Vol 12, pp. 724098. 2021 Sep 24. Ma WLyu HPandya MGopinathan GLuan XDiekwisch TGH Successful Application of a Galanin-Coated Scaffold for Periodontal Regeneration.; Journal of dental research; Vol 100(10), pp. 1144-1152. 2021 Jul 30. Pandya MLyu HLuan XDiekwisch TGH Polarized, Amelogenin Expressing Ameloblast-Like Cells from Cervical Loop/Dental Pulp Cocultures in Bioreactors.; Stem cells and development; Vol 30(16), pp. 797-805. 2021 Jul 19. Luan XZhou XFallah PPandya MLyu HFoyle DBurch DDiekwisch TGH MicroRNAs: Harbingers and shapers of periodontal inflammation.; Seminars in cell & developmental biology; Vol 124, pp. 85-98. 2021 Jun 10. Pandya MMa WLyu HLuan XDiekwisch TGH Propagation of Dental and Respiratory Cells and Organs in Microgravity.; Journal of visualized experiments : JoVE. 2021 May 25. Pandya MSaxon MBozanich JTillberg CLuan XDiekwisch TGH The Glycoprotein/Cytokine Erythropoietin Promotes Rapid Alveolar Ridge Regeneration In Vivo by Promoting New Bone Extracellular Matrix Deposition in Conjunction with Coupled Angiogenesis/Osteogenesis.; International journal of molecular sciences; Vol 22(6). 2021 Mar 10. Pandya MDiekwisch TGH Amelogenesis: Transformation of a protein-mineral matrix into tooth enamel.; Journal of structural biology; Vol 213(4), pp. 107809. 2021 Jan 06. Francis MGopinathan GFoyle DFallah PGonzalez MLuan XDiekwisch TGH Histone Methylation: Achilles Heel and Powerful Mediator of Periodontal Homeostasis.; Journal of dental research; Vol 99(12), pp. 1332-1340. 2020 Aug 07. Francis MGopinathan GSalapatas ANares SGonzalez MDiekwisch TGHLuan X SETD1 and NF-κB Regulate Periodontal Inflammation through H3K4 Trimethylation.; Journal of dental research; Vol 99(13), pp. 1486-1493. 2020 Aug 07. Diekwisch TGH Evolution: Herbivore-Type Teeth in a Cretaceous Tuatara Relative.; Current biology : CB; Vol 30(9), pp. R395-R397. 2020 May 04. Gopinathan GFoyle DLuan XDiekwisch TGH The Wnt Antagonist SFRP1: A Key Regulator of Periodontal Mineral Homeostasis.; Stem cells and development; Vol 28(15), pp. 1004-1014. 2019 Jul 22. Diekwisch TGH Periodontal Homeostasis: From Vienna to Texas-A Century of Periodontal Research in the Spirit of Bernhard Gottlieb.; Stem cells and development; Vol 28(15), pp. 961-962. 2019 Jul 22. Jokisaari JRWang CQiao QHu XReed DABleher RLuan XKlie RFDiekwisch TGH Particle-Attachment-Mediated and Matrix/Lattice-Guided Enamel Apatite Crystal Growth.; ACS nano; Vol 13(3), pp. 3151-3161. 2019 Feb 25. Isaac AJivan FXin SHardin JLuan XPandya MDiekwisch TGHAlge DL Microporous Bio-orthogonally Annealed Particle Hydrogels for Tissue Engineering and Regenerative Medicine.; ACS biomaterials science & engineering; Vol 5(12), pp. 6395-6404. 2019 Jan 11. Qian YZhou XZhang FDiekwisch TGHLuan XYang J Triple PLGA/PCL Scaffold Modification Including Silver Impregnation, Collagen Coating, and Electrospinning Significantly Improve Biocompatibility, Antimicrobial, and Osteogenic Properties for Orofacial Tissue Regeneration.; ACS applied materials & interfaces; Vol 11(41), pp. 37381-37396. 2019 Jan 07. Pandya MDiekwisch TGH Enamel biomimetics-fiction or future of dentistry.; International journal of oral science; Vol 11(1), pp. 8. 2019 Jan 05. Luan XZhou XNaqvi AFrancis MFoyle DNares SDiekwisch TGH MicroRNAs and immunity in periodontal health and disease.; International journal of oral science; Vol 10(3), pp. 24. 2018 Aug 06. Harrel SKWilson TGPandya MDiekwisch TGH Titanium particles generated during ultrasonic scaling of implants.; Journal of periodontology; Vol 90(3), pp. 241-246. 2018 Jan 14. Kirkham JBrookes SJDiekwisch TGHMargolis HCBerdal AHubbard MJ Enamel Research: Priorities and Future Directions.; Frontiers in physiology; Vol 8, pp. 513. 2017 Jul 20. Pandya MLiu HDangaria SJZhu WLi LLPan SAbufarwa MDavis RGGuggenheim SKeiderling TLuan XDiekwisch TGH Integrative Temporo-Spatial, Mineralogic, Spectroscopic, and Proteomic Analysis of Postnatal Enamel Development in Teeth with Limited Growth.; Frontiers in physiology; Vol 8, pp. 793. 2017 Jan 24. Klein ODDuverger OShaw WLacruz RSJoester DMoradian-Oldak JPugach MKWright JTMillar SEKulkarni ABBartlett JDDiekwisch TGDenBesten PSimmer JP Meeting report: a hard look at the state of enamel research.; International journal of oral science; Vol 9(11), pp. e3. 2017 Jan 22. Pandya MLin TLi LAllen MJJin TLuan XDiekwisch TGH Posttranslational Amelogenin Processing and Changes in Matrix Assembly during Enamel Development.; Frontiers in physiology; Vol 8, pp. 790. 2017 Jan 17. Pandya MRosene LFarquharson CMillán JLDiekwisch TGH Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation.; Frontiers in physiology; Vol 8, pp. 805. 2017 Jan 17. Luan XZhou XTrombetta-eSilva JFrancis MGaharwar AKAtsawasuwan PDiekwisch TGH MicroRNAs and Periodontal Homeostasis.; Journal of dental research; Vol 96(5), pp. 491-500. 2017 Jan 09. Liu HYan XPandya MLuan XDiekwisch TG Daughters of the Enamel Organ: Development, Fate, and Function of the Stratum Intermedium, Stellate Reticulum, and Outer Enamel Epithelium.; Stem cells and development; Vol 25(20), pp. 1580-1590. 2016 Sep 09. Diekwisch TG Novel approaches toward managing the micromanagers: 'non-toxic' but effective.; Gene therapy; Vol 23(10), pp. 697-698. 2016 Jul 07. Liu MReed DACecchini GMLu XGanjawalla KGonzales CSMonahan RLuan XDiekwisch TG Varanoid Tooth Eruption and Implantation Modes in a Late Cretaceous Mosasaur.; Frontiers in physiology; Vol 7, pp. 145. 2016 May 17. Diekwisch TG Our periodontal tissue: a masterpiece of evolution.; Journal of clinical periodontology; Vol 43(4), pp. 320-2. 2016 Mar 29. Lu XFukumoto SYamada YEvans CADiekwisch TGLuan X Ameloblastin, an Extracellular Matrix Protein, Affects Long Bone Growth and Mineralization.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 31(6), pp. 1235-46. 2016 Feb 26. Lu XLi WFukumoto SYamada YEvans CADiekwisch TLuan X The ameloblastin extracellular matrix molecule enhances bone fracture resistance and promotes rapid bone fracture healing.; Matrix biology : journal of the International Society for Matrix Biology; Vol 52-54, pp. 113-126. 2016 Feb 18. Diekwisch TG Oral Biology and Chicago.; Evolution & development; Vol 18(1), pp. 3-6. 2016. Reed DAIriarte-Diaz JDiekwisch TG A three dimensional free body analysis describing variation in the musculoskeletal configuration of the cynodont lower jaw.; Evolution & development; Vol 18(1), pp. 41-53. 2016. Mao YSatchell PGLuan XDiekwisch TG SM50 repeat-polypeptides self-assemble into discrete matrix subunits and promote appositional calcium carbonate crystal growth during sea urchin tooth biomineralization.; Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft; Vol 203, pp. 38-46. 2015 Jul 06. Chen YMohammed AOubaidin MEvans CAZhou XLuan XDiekwisch TGAtsawasuwan P Cyclic stretch and compression forces alter microRNA-29 expression of human periodontal ligament cells.; Gene; Vol 566(1), pp. 13-7. 2015 Mar 28. Zhou XLuan XChen ZFrancis MGopinathan GLi WLu XLi SWu CDiekwisch TG MicroRNA-138 Inhibits Periodontal Progenitor Differentiation under Inflammatory Conditions.; Journal of dental research; Vol 95(2), pp. 230-7. 2015 Jan 30. Li QReed DAMin LGopinathan GLi SDangaria SJLi LGeng YGalang MTGajendrareddy PZhou YLuan XDiekwisch TG Lyophilized platelet-rich fibrin (PRF) promotes craniofacial bone regeneration through Runx2.; International journal of molecular sciences; Vol 15(5), pp. 8509-25. 2014 May 14. Lovaglio JArtwohl JEWard CJDiekwisch TGIto YFortman JD Case study: polycystic livers in a transgenic mouse line.; Comparative medicine; Vol 64(2), pp. 115-20. 2014 Apr. Hasturk HKantarci AGhattas MDangaria SJAbdallah RMorgan EFDiekwisch TGAshman AVan Dyke T The use of light/chemically hardened polymethylmethacrylate, polyhydroxylethylmethacrylate, and calcium hydroxide graft material in combination with polyanhydride around implants and extraction sockets in minipigs: Part II: histologic and micro-CT evaluations.; Journal of periodontology; Vol 85(9), pp. 1230-9. 2014 Feb 06. Wang MLi SXie WShen JIm HJHolz JDWang MDiekwisch TGChen D Activation of β-catenin signalling leads to temporomandibular joint defects.; European cells & materials; Vol 28, pp. 223-35. 2014 Jan 23. Gopinathan GJin TLiu MLi SAtsawasuwan PGalang MTAllen MLuan XDiekwisch TG The expanded amelogenin polyproline region preferentially binds to apatite versus carbonate and promotes apatite crystal elongation.; Frontiers in physiology; Vol 5, pp. 430. 2014 Jan 11. Goodwin AFTidyman WEJheon AHSharir AZheng XCharles CFagin JAMcMahon MDiekwisch TGGanss BRauen KAKlein OD Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation.; Human molecular genetics; Vol 23(3), pp. 682-92. 2013 Sep 20. Wang XXing ZZhang XZhu LDiekwisch TG Alternative Splicing of the Amelogenin Gene in a Caudate Amphibian, Plethodon cinereus.; PloS one; Vol 8(6), pp. e68965. 2013 Jun 26. Atsawasuwan PLu XIto YChen YGopinathan GEvans CAKulkarni ABGibson CWLuan XDiekwisch TG Expression and function of enamel-related gene products in calvarial development.; Journal of dental research; Vol 92(7), pp. 622-8. 2013 Apr 26. Gopinathan GKolokythas ALuan XDiekwisch TG Epigenetic marks define the lineage and differentiation potential of two distinct neural crest-derived intermediate odontogenic progenitor populations.; Stem cells and development; Vol 22(12), pp. 1763-78. 2013 Mar 15. Huang JZhao DDangaria SJLuan XDiekwisch TGJiang GSaiz ELiu GTomsia AP Combinatorial Design of Hydrolytically Degradable, Bone-like Biocomposites Based on PHEMA and Hydroxyapatite.; Polymer; Vol 54(2), pp. 909-919. 2012 Jan 13. Lu XIto YKulkarni AGibson CLuan XDiekwisch TG Ameloblastin-rich enamel matrix favors short and randomly oriented apatite crystals.; European journal of oral sciences; Vol 119 Suppl 1(Suppl 1), pp. 254-60. 2011 Dec.