Publications

• 1. Perrelli A
  2. Ferraris C
  3. Berni E
  4. Glading AJ
  5. Retta SF
  KRIT1: a traffic warden at the busy crossroads between redox signaling and the pathogenesis of Cerebral Cavernous Malformation disease.; Antioxidants & redox signaling. 2022 Sep 01.
• 1. Swamy H
  2. Glading AJ
  Is Location Everything? Regulation of the Endothelial CCM Signaling Complex.; Frontiers in cardiovascular medicine; Vol 9, pp. 954780. 2022 Jul 11.
• 1. Swamy H
  2. Glading AJ
  Contribution of protein-protein interactions to the endothelial barrier-stabilizing function of KRIT1.; Journal of cell science. 2021 Dec 17.
• 1. De Luca E
  2. Perrelli A
  3. Swamy H
  4. Nitti M
  5. Passalacqua M
  6. Furfaro AL
  7. Salzano AM
  8. Scaloni A
  9. Glading AJ
  10. Retta SF
  Protein kinase Cα (PKCα) regulates the nucleocytoplasmic shuttling of KRIT1.; Journal of cell science. 2020 Dec 21.
• 1. Khire TS
  2. Salminen AT
  3. Swamy H
  4. Lucas KS
  5. McCloskey MC
  6. Ajalik RE
  7. Chung HH
  8. Gaborski TR
  9. Waugh RE
  10. Glading AJ
  11. McGrath JL
  Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions.; Cellular and molecular bioengineering; Vol 13(2). 2020 Apr.
• 1. De Luca E
  2. Perrelli A
  3. Swamy H
  4. Nitti M
  5. Passalacqua M
  6. Furfaro AL
  7. Salzano AM
  8. Scaloni A
  9. Glading AJ
  10. Retta SF
  Protein kinase Cα (PKCα) regulates the nucleocytoplasmic shuttling of KRIT1.; Journal of cell science. 2020 Jan 01.
• 1. Nobiletti N
  2. Glading AJ
  Isolation of Cerebral Endothelial Cells from CCM1/KRIT1 Null Mouse Brain.; Methods in molecular biology (Clifton, N.J.); Vol 2152. 2020.
• 1. DiStefano PV
  2. Glading AJ
  VEGF signalling enhances lesion burden in KRIT1 deficient mice.; Journal of cellular and molecular medicine; Vol 24(1). 2020 Jan.
• 1. Glading AJ
  Measurement of Endothelial Barrier Function in Mouse Models of Cerebral Cavernous Malformations Using Intravital Microscopy.; Methods in molecular biology (Clifton, N.J.); Vol 2152. 2020.
• 1. Goitre L
  2. DiStefano PV
  3. Moglia A
  4. Nobiletti N
  5. Baldini E
  6. Trabalzini L
  7. Keubel J
  8. Trapani E
  9. Shuvaev VV
  10. Muzykantov VR
  11. Sarelius IH
  12. Retta SF
  13. Glading AJ
  Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium.; Scientific reports; Vol 7(1). 2017 Aug 15.
• 1. DiStefano PV
  2. Smrcka AV
  3. Glading AJ
  Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier.; PloS one; Vol 11(9). 2016.
• 1. Retta SF
  2. Glading AJ
  Oxidative stress and inflammation in cerebral cavernous malformation disease pathogenesis: Two sides of the same coin.; The international journal of biochemistry & cell biology; Vol 81(Pt B). 2016 Jan.
• 1. Sarelius IH
  2. Glading AJ
  Control of vascular permeability by adhesion molecules.; Tissue barriers; Vol 3(1-2). 2015.
• 1. DiStefano PV
  2. Kuebel JM
  3. Sarelius IH
  4. Glading AJ
  KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling.; The Journal of biological chemistry; Vol 289(47). 2014 Nov 21.
• 1. Corr M
  2. Lerman I
  3. Keubel JM
  4. Ronacher L
  5. Misra R
  6. Lund F
  7. Sarelius IH
  8. Glading AJ
  Decreased Krev interaction-trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo.; Arteriosclerosis, thrombosis, and vascular biology; Vol 32(11). 2012 Nov.
• 1. Glading AJ
  2. Ginsberg MH
  Rap1 and its effector KRIT1/CCM1 regulate beta-catenin signaling.; Disease models & mechanisms; Vol 3(1-2). 2010 Jan.
• 1. Glading A
  2. Han J
  3. Stockton RA
  4. Ginsberg MH
  KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions.; The Journal of cell biology; Vol 179(2). 2007 Oct 22.
• 1. Glading A
  2. Koziol JA
  3. Krueger J
  4. Ginsberg MH
  PEA-15 inhibits tumor cell invasion by binding to extracellular signal-regulated kinase 1/2.; Cancer research; Vol 67(4). 2007 Feb 15.
• 1. Krueger J
  2. Chou FL
  3. Glading A
  4. Schaefer E
  5. Ginsberg MH
  Phosphorylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation.; Molecular biology of the cell; Vol 16(8). 2005 Aug.
• 1. Satish L
  2. Blair HC
  3. Glading A
  4. Wells A
  Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain.; Molecular and cellular biology; Vol 25(5). 2005 Mar.
• 1. Glading A
  2. Bodnar RJ
  3. Reynolds IJ
  4. Shiraha H
  5. Satish L
  6. Potter DA
  7. Blair HC
  8. Wells A
  Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation.; Molecular and cellular biology; Vol 24(6). 2004 Mar.
• 1. Chou FL
  2. Hill JM
  3. Hsieh JC
  4. Pouyssegur J
  5. Brunet A
  6. Glading A
  7. Uberall F
  8. Ramos JW
  9. Werner MH
  10. Ginsberg MH
  PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation.; The Journal of biological chemistry; Vol 278(52). 2003 Dec 26.
• 1. Shiraha H
  2. Glading A
  3. Chou J
  4. Jia Z
  5. Wells A
  Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain.; Molecular and cellular biology; Vol 22(8). 2002 Apr.
• 1. Glading A
  2. Lauffenburger DA
  3. Wells A
  Cutting to the chase: calpain proteases in cell motility.; Trends in cell biology; Vol 12(1). 2002 Jan.
• 1. Glading A
  2. Uberall F
  3. Keyse SM
  4. Lauffenburger DA
  5. Wells A
  Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.; The Journal of biological chemistry; Vol 276(26). 2001 Jun 29.
• 1. Glading A
  2. Chang P
  3. Lauffenburger DA
  4. Wells A
  Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway.; The Journal of biological chemistry; Vol 275(4). 2000 Jan 28.
• 1. Shiraha H
  2. Glading A
  3. Gupta K
  4. Wells A
  IP-10 inhibits epidermal growth factor-induced motility by decreasing epidermal growth factor receptor-mediated calpain activity.; The Journal of cell biology; Vol 146(1). 1999 Jul 12.
• 1. Wells A
  2. Gupta K
  3. Chang P
  4. Swindle S
  5. Glading A
  6. Shiraha H
  Epidermal growth factor receptor-mediated motility in fibroblasts.; Microscopy research and technique; Vol 43(5). 1998 Dec 1.