URMC / Labs / Hayes Lab / Publications Recent Publications Marr LClark DJHayes JJ A method for assessing histone surface accessibility genome-wide.; Methods (San Diego, Calif.). 2019 Dec 09. Tucker CBhattacharya SWakabayashi HBellaousov SKravets AWelle SLMyers JHayes JJBulger MRustchenko E Author Correction: Transcriptional Regulation on Aneuploid Chromosomes in Diverse Candida albicans Mutants.; Scientific reports; Vol 9(1). 2019 Jul 05. Mishra LNHayes JJ A nucleosome-free region locally abrogates histone H1-dependent restriction of linker DNA accessibility in chromatin.; The Journal of biological chemistry; Vol 293(50). 2018 Dec 14. Tucker CBhattacharya SWakabayashi HBellaousov SKravets AWelle SLMyers JHayes JJBulger MRustchenko E Transcriptional Regulation on Aneuploid Chromosomes in Divers Candida albicans Mutants.; Scientific reports; Vol 8(1). 2018 Jan 26. Gatchalian JWang XIkebe JCox KLTencer AHZhang YBurge NLDi LGibson MDMusselman CAPoirier MGKono HHayes JJKutateladze TG Accessibility of the histone H3 tail in the nucleosome for binding of paired readers.; Nature communications; Vol 8(1). 2017 Nov 14. Wakabayashi HTucker CBethlendy GKravets AWelle SLBulger MHayes JJRustchenko E Correction to: NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins.; Epigenetics & chromatin; Vol 10(1). 2017 Nov 07. Wakabayashi HTucker CBethlendy GKravets AWelle SLBulger MHayes JRustchenko E NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins.; Epigenetics & chromatin; Vol 10(1). 2017 Oct 23. Tencer AHCox KLDi LBridgers JBLyu JWang XSims JKWeaver TMAllen HFZhang YGatchalian JDarcy MAGibson MDIkebe JLi WWade PAHayes JJStrahl BDKono HPoirier MGMusselman CAKutateladze TG Covalent Modifications of Histone H3K9 Promote Binding of CHD3.; Cell reports; Vol 21(2). 2017 Oct 10. Murphy KJCutter ARFang HPostnikov YVBustin MHayes JJ HMGN1 and 2 remodel core and linker histone tail domains within chromatin.; Nucleic acids research; Vol 45(17). 2017 Sep 29. Bednar JGarcia-Saez IBoopathi RCutter ARPapai GReymer ASyed SHLone INTonchev OCrucifix CMenoni HPapin CSkoufias DAKurumizaka HLavery RHamiche AHayes JJSchultz PAngelov DPetosa CDimitrov S Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.; Molecular cell; Vol 66(5). 2017 Jun 01. Bednar JGarcia-Saez IBoopathi RCutter ARPapai GReymer ASyed SHLone INTonchev OCrucifix CMenoni HPapin CSkoufias DAKurumizaka HLavery RHamiche AHayes JJSchultz PAngelov DPetosa CDimitrov S Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.; Molecular cell; Vol 66(3). 2017 May 04. Cutter ARHayes JJ Linker histones: novel insights into structure-specific recognition of the nucleosome.; Biochemistry and cell biology = Biochimie et biologie cellulaire; Vol 95(2). 2017 Apr. Balliano AHao FNjeri CBalakrishnan LHayes JJ HMGB1 Stimulates Activity of Polymerase β on Nucleosome Substrates.; Biochemistry. 2017 Jan 18. Fang HWei SLee THHayes JJ Chromatin structure-dependent conformations of the H1 CTD.; Nucleic acids research; Vol 44(19). 2016 Nov 02. Mishra LNPepenella SRogge RHansen JCHayes JJ Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays.; Scientific reports; Vol 6. 2016 Oct 06. Black PJMiller ASHayes JJ Radioresistance of GGG sequences to prompt strand break formation from direct-type radiation damage.; Radiation and environmental biophysics. 2016 Jun 27. Yue HFang HWei SHayes JJLee TH Single-Molecule Studies of the Linker Histone H1 Binding to DNA and the Nucleosome.; Biochemistry; Vol 55(14). 2016 Apr 12. Balliano AJHayes JJ Base excision repair in chromatin: Insights from reconstituted systems.; DNA repair; Vol 36. 2015 Dec. Cutter ARHayes JJ A brief review of nucleosome structure.; FEBS letters; Vol 589(20 Pt A). 2015 Oct 7. Pepenella SMurphy KJHayes JJ A distinct switch in interactions of the histone H4 tail domain upon salt-dependent folding of nucleosome arrays.; The Journal of biological chemistry; Vol 289(39). 2014 Sep 26. Pepenella SMurphy KJHayes JJ Intra- and inter-nucleosome interactions of the core histone tail domains in higher-order chromatin structure.; Chromosoma; Vol 123(1-2). 2014 Mar. Raghuram NStrickfaden HMcDonald DWilliams KFang HMizzen CHayes JJTh'ng JHendzel MJ Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin.; The Journal of cell biology; Vol 203(1). 2013 Oct 14. Elliott GOMurphy KJHayes JJThiriet C Replication-independent nucleosome exchange is enhanced by local and specific acetylation of histone H4.; Nucleic acids research; Vol 41(4). 2013 Feb 1. Fang HClark DJHayes JJ DNA and nucleosomes direct distinct folding of a linker histone H1 C-terminal domain.; Nucleic acids research; Vol 40(4). 2012 Feb. Liu NHayes JJ Preparation of nucleosomes containing a specific H2A-H2A cross-link forming a DNA-constraining loop structure.; Methods in molecular biology (Clifton, N.J.); Vol 833. 2012. Yang ZHayes JJ The divalent cations Ca2+ and Mg2+ play specific roles in stabilizing histone-DNA interactions within nucleosomes that are partially redundant with the core histone tail domains.; Biochemistry; Vol 50(46). 2011 Nov 22. Meyer SBecker NBSyed SHGoutte-Gattat DShukla MSHayes JJAngelov DBednar JDimitrov SEveraers R From crystal and NMR structures, footprints and cryo-electron-micrographs to large and soft structures: nanoscale modeling of the nucleosomal stem.; Nucleic acids research; Vol 39(21). 2011 Nov. Liu NPeterson CLHayes JJ SWI/SNF- and RSC-catalyzed nucleosome mobilization requires internal DNA loop translocation within nucleosomes.; Molecular and cellular biology; Vol 31(20). 2011 Oct. Almouzni GHayes JJ International symposium on the physicochemical field for genetic activities. Awaji Island, Japan, January 24–26, 2011.; Nucleus (Austin, Tex.); Vol 2(4). 2011 Jul. Caterino TLFang HHayes JJ Nucleosome linker DNA contacts and induces specific folding of the intrinsically disordered H1 carboxyl-terminal domain.; Molecular and cellular biology; Vol 31(11). 2011 Jun. Jagannathan IPepenella SHayes JJ Activity of FEN1 endonuclease on nucleosome substrates is dependent upon DNA sequence but not flap orientation.; The Journal of biological chemistry; Vol 286(20). 2011 May 20. Shukla MSSyed SHGoutte-Gattat DRichard JLMontel FHamiche ATravers AFaivre-Moskalenko CBednar JHayes JJAngelov DDimitrov S The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling.; Nucleic acids research; Vol 39(7). 2011 Apr. Caterino TLHayes JJ Structure of the H1 C-terminal domain and function in chromatin condensation.; Biochemistry and cell biology = Biochimie et biologie cellulaire; Vol 89(1). 2011 Feb. Liu NBalliano AHayes JJ Mechanism(s) of SWI/SNF-induced nucleosome mobilization.; Chembiochem : a European journal of chemical biology; Vol 12(2). 2011 Jan 24. Liu NHayes JJ When push comes to shove: SWI/SNF uses a nucleosome to get rid of a nucleosome.; Molecular cell; Vol 38(4). 2010 May 28. Syed SHGoutte-Gattat DBecker NMeyer SShukla MSHayes JJEveraers RAngelov DBednar JDimitrov S Single-base resolution mapping of H1-nucleosome interactions and 3D organization of the nucleosome.; Proceedings of the National Academy of Sciences of the United States of America; Vol 107(21). 2010 May 25. Cole HATabor-Godwin JMHayes JJ Uracil DNA glycosylase activity on nucleosomal DNA depends on rotational orientation of targets.; The Journal of biological chemistry; Vol 285(4). 2010 Jan 22. Thiriet CHayes JJ Linker histone phosphorylation regulates global timing of replication origin firing.; The Journal of biological chemistry; Vol 284(5). 2009 Jan 30. Kan PYCaterino TLHayes JJ The H4 tail domain participates in intra- and internucleosome interactions with protein and DNA during folding and oligomerization of nucleosome arrays.; Molecular and cellular biology; Vol 29(2). 2009 Jan. Jagannathan IHayes JJ Hydroxyl radical footprinting of protein-DNA complexes.; Methods in molecular biology (Clifton, N.J.); Vol 543. 2009. Chafin DRHayes JJ Site-directed cleavage of DNA by protein-Fe(II) EDTA conjugates within model chromatin complexes.; Methods in molecular biology (Clifton, N.J.); Vol 543. 2009. Wang XHayes JJ Acetylation mimics within individual core histone tail domains indicate distinct roles in regulating the stability of higher-order chromatin structure.; Molecular and cellular biology; Vol 28(1). 2008 Jan. Wang XHayes JJ Site-specific binding affinities within the H2B tail domain indicate specific effects of lysine acetylation.; The Journal of biological chemistry; Vol 282(45). 2007 Nov 9. Caterino TLHayes JJ Chromatin structure depends on what's in the nucleosome's pocket.; Nature structural & molecular biology; Vol 14(11). 2007 Nov. Yang ZZheng CHayes JJ The core histone tail domains contribute to sequence-dependent nucleosome positioning.; The Journal of biological chemistry; Vol 282(11). 2007 Mar 16. Kan PYHayes JJ Detection of interactions between nucleosome arrays mediated by specific core histone tail domains.; Methods (San Diego, Calif.); Vol 41(3). 2007 Mar. Kan PYLu XHansen JCHayes JJ The H3 tail domain participates in multiple interactions during folding and self-association of nucleosome arrays.; Molecular and cellular biology; Vol 27(6). 2007 Mar. Wang XHayes JJ Physical methods used to study core histone tail structures and interactions in solution.; Biochemistry and cell biology = Biochimie et biologie cellulaire; Vol 84(4). 2006 Aug. Jagannathan ICole HAHayes JJ Base excision repair in nucleosome substrates.; Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology; Vol 14(1). 2006. Thiriet CHayes JJ Histone dynamics during transcription: exchange of H2A/H2B dimers and H3/H4 tetramers during pol II elongation.; Results and problems in cell differentiation; Vol 41. 2006.