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Herrera Lab

Welcome to the Functional Multicellular Systems Lab

The Herrera Lab specializes in the study of principles and applications of cellular self-organization. We study both cell-cell and cell-environment dynamic relationships that drive the emergence of structure and function in multicellular systems. We are particularly interested in the role of the cellular microenvironment (mechanical cues and external constraints) as dynamic factors controlling tissue self-organization. We currently perform experiments with cell engineering, molecular biology, advanced confocal microscopy, and cell mechanics in cultured cells and in the developing embryo of the fruit fly. The long-term goal of our research centers in the construction of organized living structures with designed functionalities and three-dimensional forms that can be used to improve tissues models and to develop new engineered biological machines.

Marisol Herrera-Perez


Herrera-Perez, RM, Cupo, C., Allan, C.J. Dagle, A.B. and Kasza, K.E. 2022. Optogenetic dissection of actomyosin-dependent mechanics underlying tissue fluidity. 2022, doi: 10.1101/2021.11.07.467642

Herrera-Perez RM, Cupo C, Allan C, Lin A, Kasza KE. Using optogenetics to link myosin patterns to contractile cell behaviors during convergent extension. Biophys J. 2021 Oct 5;120(19):4214-4229. doi: 10.1016/j.bpj.2021.06.041. Epub 2021 Jul 20. PubMed PMID: 34293302; PubMed Central PMCID: PMC8516680.

Herrera-Perez RM, Kasza KE. Manipulating the Patterns of Mechanical Forces That Shape Multicellular Tissues. Physiology (Bethesda). 2019 Nov 1;34(6):381-391. doi: 10.1152/physiol.00018.2019. Review. PubMed PMID: 31577169.

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