URMC / Labs / Holt Lab / Publications Recent Publications Poppi LATabatabaee HDrury HRJobling PCallister RJMigliaccio AAJordan PMHolt JCRabbitt RDLim RBrichta AM (2017 Oct 04). ACh-induced hyperpolarization and decreased resistance in mammalian type II vestibular hair cells. Journal of neurophysiology. Lee CHolt JCJones TA (2017 Aug 30). The effect of M-current modulation on mammalian vestibular responses to transient head motion. Journal of neurophysiology. Holt JCJordan PMLysakowski AShah ABarsz KContini D (2017 Feb 15). Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents. The Journal of neuroscience : the official journal of the Society for Neuroscience. Dickerson IMBussey-Gaborski RHolt JCJordan PMLuebke AE (2016 Jul). Maturation of suprathreshold auditory nerve activity involves cochlear CGRP-receptor complex formation. Physiological reports. Jordan PMFettis MHolt JC (2015 Jun 1). Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse. The Journal of comparative neurology. Holt JCKewin KJordan PMCameron PKlapczynski MMcIntosh JMCrooks PADwoskin LPLysakowski A (2015 Feb 25). Pharmacologically distinct nicotinic acetylcholine receptors drive efferent-mediated excitation in calyx-bearing vestibular afferents. The Journal of neuroscience : the official journal of the Society for Neuroscience. Luebke AEHolt JCJordan PMWong YSCaldwell JSCullen KE (2014 Jul 30). Loss of α-Calcitonin Gene-Related Peptide (αCGRP) Reduces the Efficacy of the Vestibulo-ocular Reflex (VOR). The Journal of neuroscience : the official journal of the Society for Neuroscience. Jordan PMParks XXContini DHolt JC (2013). A review of synaptic mechanisms of vestibular efferent signaling in turtles: extrapolation to efferent actions in mammals. Journal of vestibular research : equilibrium & orientation. Holt JCChatlani SLysakowski AGoldberg JM (2007 Sep). Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista. Journal of neurophysiology. Holt JCLysakowski AGoldberg JM (2006 Dec 20). Mechanisms of efferent-mediated responses in the turtle posterior crista. The Journal of neuroscience : the official journal of the Society for Neuroscience. Holt JCXue JTBrichta AMGoldberg JM (2006 Jan). Transmission between type II hair cells and bouton afferents in the turtle posterior crista. Journal of neurophysiology. Holt JCLioudyno MGuth PS (2003 Sep). A pharmacologically distinct nicotinic ACh receptor is found in a subset of frog semicircular canal hair cells. Journal of neurophysiology. Lioudyno MIVerbitsky MGlowatzki EHolt JCBoulter JZadina JEElgoyhen ABGuth PS (2002 Aug). The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear. Molecular and cellular neurosciences. Holt JCLioudyno MAthas GGarcia MMPerin PGuth PS (2001 Feb). The effect of proteolytic enzymes on the alpha9-nicotinic receptor-mediated response in isolated frog vestibular hair cells. Hearing research. Lioudyno MIVerbitsky MHolt JCElgoyhen ABGuth PS (2000 Nov). Morphine inhibits an alpha9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors. Hearing research. Holt JCPantoja AMAthas GBGuth PS (2000 Aug). A role for chloride in the hyperpolarizing effect of acetylcholine in isolated frog vestibular hair cells. Hearing research. Guth PSHolt JCPerin PAthas GGarcia MPuri AZucca GBotta LValli P (1998 Nov). The metabotropic glutamate receptors of the vestibular organs. Hearing research. Norris CHMiller AJPerin PHolt JCGuth PS (1998 Sep). Mechanisms and effects of transepithelial polarization in the isolated semicircular canal. Hearing research. Pantoja AMHolt JCGuth PS (1997 Oct). A role for chloride in the suppressive effect of acetylcholine on afferent vestibular activity. Hearing research. Michel REHolt JCDomer FR (1996 Feb). Ketorolac causes the release of methionine-enkephalin in rats. Research communications in molecular pathology and pharmacology.