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URMC / Labs / Iqbal Lab / Projects / Measuring Genomic Stability in Cytopenic Patients

Measuring Genomic Stability in Cytopenic Patients

This project evaluates the degree of genomic instability (measured by combine CGH-SNP microarray) relative to the number of MDS-associated mutations (measured by next-generation sequencing) among cytopenic patients that underwent non-diagnostic bone marrow evaluation for MDS (i.e. patient’s diagnosed with idiopathic cytopenias(s) of uncertain significance, or ICUS). Compare the relative sensitivity and specificity of each testing platform for identifying malignant clonal hematopoiesis.

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