URMC / Labs / Lawrence Lab / Publications Publications Boulé LAChapman TJHillman SEKassotis CDO'Dell CRobert JGeoras SNNagel SCLawrence BP Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 May 01. Boule LABurke CGJin GBLawrence BP Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome.; Scientific reports; Vol 81. 2018 Jan 29. Yee MDomm WGelein RBentley KLKottmann RMSime PJLawrence BPO'Reilly MA Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.; American journal of respiratory cell and molecular biology; Vol 564. 2017 Apr. De Jesús Andino FLawrence BPRobert J Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis.; Chemosphere; Vol 170. 2017 Mar. Hessel EVEzendam JBroekhuizen FAHakkert BDeWitt JGranum BGuzylack LLawrence BPPenninks ARooney AAPiersma AHLoveren HV Assessment of recent developmental immunotoxicity studies with bisphenol A in the context of the 2015 EFSA t-TDI.; Reproductive toxicology (Elmsford, N.Y.). 2016 Jun 25. Jusko TADe Roos AJLee SYThevenet-Morrison KSchwartz SMVerner MAMurinova LPDrobná BKočan AFabišiková AČonka KTrnovec THertz-Picciotto ILawrence BP A Birth Cohort Study of Maternal and Infant Serum PCB-153 and DDE Concentrations and Responses to Infant Tuberculosis Vaccination.; Environmental health perspectives; Vol 1246. 2016 Jun. Jusko TOktapodas MPalkovičová Murinová ĽBabinska KBabjakova JVerner MADeWitt JThevenet-Morrison KConka KDrobná BChovancova JThurston SLawrence BPDozier AJarvinen KPatayova HTrnovec TLegler JHertz-Picciotto ILamoree MH Demographic, reproductive, and dietary determinants of perfluorooctane sulfonic (PFOS) and perfluorooctanoic acid (PFOA) concentrations in human colostrum.; Environmental science & technology. 2016 May 31. Yee MGelein RMariani TJLawrence BPO'Reilly MA The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung.; Stem cells (Dayton, Ohio); Vol 345. 2016 May. Boule LABurke CGFenton BMThevenet-Morrison KJusko TALawrence BP Developmental Activation of the AHR Increases Effector CD4+ T Cells and Exacerbates Symptoms in Autoimmune Disease-Prone Gnaq+/- Mice.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1482. 2015 Dec. Boule LAWinans BLambert KVorderstrasse BATopham DJPavelka MSLawrence BP Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 3093. 2015 Aug 1. Winans BNagari AChae MPost CMKo CIPuga AKraus WLLawrence BP Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.; Journal of immunology (Baltimore, Md. : 1950); Vol 1949. 2015 May 1. Reilly ECMartin KCJin GBYee MO'Reilly MALawrence BP Neonatal hyperoxia leads to persistent alterations in NK responses to influenza A virus infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 3081. 2015 Jan 1. Sundar IKAhmad TYao HHwang JWGerloff JLawrence BPSellix MTRahman I Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.; Scientific reports; Vol 4. 2015. Sobolewski MConrad KAllen JLWeston HMartin KLawrence BPCory-Slechta DA Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals.; Neurotoxicology; Vol 45. 2014 Dec. Sifkarovski JGrayfer LDe Jesús Andino FLawrence BPRobert J Negative effects of low dose atrazine exposure on the development of effective immunity to FV3 in Xenopus laevis.; Developmental and comparative immunology; Vol 471. 2014 Nov. Boule LAWinans BLawrence BP Effects of developmental activation of the AhR on CD4+ T-cell responses to influenza virus infection in adult mice.; Environmental health perspectives; Vol 12211. 2014 Nov. Jin GBWinans BMartin KCLawrence BP New insights into the role of the aryl hydrocarbon receptor in the function of CD11c⁺ cells during respiratory viral infection.; European journal of immunology; Vol 446. 2014 Jun. Maduekwe ETBuczynski BWYee MRangasamy TStevens TPLawrence BPO'Reilly MA Cumulative neonatal oxygen exposure predicts response of adult mice infected with influenza A virus.; Pediatric pulmonology. 2014 May 22. Regal JFLawrence BPJohnson ACLojovich SJO'Reilly MA Neonatal oxygen exposure alters airway hyper-responsiveness but not the response to allergen challenge in adult mice.; Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology; Vol 252. 2014 Mar. Wheeler JLMartin KCResseguie ELawrence BP Differential consequences of two distinct AhR ligands on innate and adaptive immune responses to influenza A virus.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1372. 2014 Feb. Lawrence BPVorderstrasse BA New insights into the aryl hydrocarbon receptor as a modulator of host responses to infection.; Seminars in immunopathology; Vol 356. 2013 Nov. Roy AGaylo ACao WSaubermann LJLawrence BP Neither direct nor developmental exposure to bisphenol A alters the severity of experimental inflammatory colitis in mice.; Journal of immunotoxicology; Vol 104. 2013 Oct. Buczynski BWYee MMartin KCLawrence BPO'Reilly MA Neonatal hyperoxia alters the host response to influenza A virus infection in adult mice through multiple pathways.; American journal of physiology. Lung cellular and molecular physiology; Vol 3054. 2013 Aug 15. Manning CMJohnston CJHernady EMiller JNReed CKLawrence BPWilliams JPFinkelstein JN Exacerbation of lung radiation injury by viral infection: the role of Clara cells and Clara cell secretory protein.; Radiation research; Vol 1796. 2013 Jun. Manning CMJohnston CJReed CKLawrence BPWilliams JPFinkelstein JN Lung irradiation increases mortality after influenza A virus challenge occurring late after exposure.; International journal of radiation oncology, biology, physics; Vol 861. 2013 May 1. Yee MBuczynski BWLawrence BPO'Reilly MA Neonatal hyperoxia increases sensitivity of adult mice to bleomycin-induced lung fibrosis.; American journal of respiratory cell and molecular biology; Vol 482. 2013 Feb. Wheeler JLMartin KCLawrence BP Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection.; Journal of immunology (Baltimore, Md. : 1950); Vol 1902. 2013 Jan 15. Bauer SMRoy AEmo JChapman TJGeoras SNLawrence BP The effects of maternal exposure to bisphenol A on allergic lung inflammation into adulthood.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1301. 2012 Nov. McKarns SCKerkvliet NIDean JHBonn MBCohen MDFranko JLaiosa MDLawrence BPLuebke RWLuster MIMiller PGPalmer RKPfau JCRaman PRegal JFRodgers KESchondelmeyer RSZhang XBurns-Naas LA Immunotoxicology: fifty years of global scientific progress.; Journal of immunotoxicology; Vol 94. 2012 Oct. Giannandrea MYee MO'Reilly MALawrence BP Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation.; Clinical and vaccine immunology : CVI; Vol 199. 2012 Sep. O'Reilly MAYee MBuczynski BWVitiello PFKeng PCWelle SLFinkelstein JNDean DALawrence BP Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1.; The American journal of pathology; Vol 1812. 2012 Aug. Buczynski BWYee MPaige Lawrence BO'Reilly MA Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice.; American journal of physiology. Lung cellular and molecular physiology; Vol 30210. 2012 May 15. Lawrence BPSherr DH You AhR what you eat?; Nature immunology; Vol 132. 2012 Feb. Roy ABauer SMLawrence BP Developmental exposure to bisphenol A modulates innate but not adaptive immune responses to influenza A virus infection.; PloS one; Vol 76. 2012. Lew BJManickam RLawrence BP Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues.; Biology of reproduction; Vol 846. 2011 Jun. Wang TGavin HMArlt VMLawrence BPFenton SEMedina DVorderstrasse BA Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors.; International journal of cancer; Vol 1287. 2011 Apr 1. Winans BHumble MCLawrence BP Environmental toxicants and the developing immune system: a missing link in the global battle against infectious disease?; Reproductive toxicology (Elmsford, N.Y.); Vol 313. 2011 Apr. Jusko TADe Roos AJSchwartz SMLawrence BPPalkovicova LNemessanyi TDrobna BFabisikova AKocan AJahnova EKavanagh TJTrnovec THertz-Picciotto I Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants.; Journal of immunotoxicology; Vol 81. 2011 Jan. Jin GBMoore AJHead JLNeumiller JJLawrence BP Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1162. 2010 Aug. Jusko TADe Roos AJSchwartz SMLawrence BPPalkovicova LNemessanyi TDrobna BFabisikova AKocan ASonneborn DJahnova EKavanagh TJTrnovec THertz-Picciotto I A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age.; Environmental research; Vol 1104. 2010 May. Lew BJCollins LLO'Reilly MALawrence BP Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1111. 2009 Sep. Collins LLLew BJLawrence BP TCDD exposure disrupts mammary epithelial cell differentiation and function.; Reproductive toxicology (Elmsford, N.Y.); Vol 281. 2009 Jul. Head JLLawrence BP The aryl hydrocarbon receptor is a modulator of anti-viral immunity.; Biochemical pharmacology; Vol 774. 2009 Feb 15. Lawrence BPDenison MSNovak HVorderstrasse BAHarrer NNeruda WReichel CWoisetschläger M Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound.; Blood; Vol 1124. 2008 Aug 15. O'Reilly MAMarr SHYee MMcGrath-Morrow SALawrence BP Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus.; American journal of respiratory and critical care medicine; Vol 17710. 2008 May 15. Teske SBohn AAHogaboam JPLawrence BP Aryl hydrocarbon receptor targets pathways extrinsic to bone marrow cells to enhance neutrophil recruitment during influenza virus infection.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1021. 2008 Mar. Hogaboam JPMoore AJLawrence BP The aryl hydrocarbon receptor affects distinct tissue compartments during ontogeny of the immune system.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1021. 2008 Mar. Neff-LaFord HTeske SBushnell TPLawrence BP Aryl hydrocarbon receptor activation during influenza virus infection unveils a novel pathway of IFN-gamma production by phagocytic cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 1791. 2007 Jul 1. Lawrence BP Environmental toxins as modulators of antiviral immune responses.; Viral immunology; Vol 202. 2007. Lawrence BPRoberts ADNeumiller JJCundiff JAWoodland DL Aryl hydrocarbon receptor activation impairs the priming but not the recall of influenza virus-specific CD8+ T cells in the lung.; Journal of immunology (Baltimore, Md. : 1950); Vol 1779. 2006 Nov 1.