URMC / Labs / Lawrence Lab / Publications

Recent Publications from the Lawrence Lab

1. Fenner KN
2. Healey AM
3. Franchini AM
4. Morrell CN
5. Lawrence BP
Aryl hydrocarbon receptor activation alters emergency hematopoiesis during influenza A virus infection.; Toxicological sciences : an official journal of the Society of Toxicology. 2026 Jan 24.
1. Coumoul X
2. Barouki R
3. Esser C
4. Haarmann-Stemmann T
5. Lawrence BP
6. Lehmann J
7. Moura-Alves P
8. Murray IA
9. Opitz CA
10. Perdew GH
11. Bourguet W
The aryl hydrocarbon receptor: structure, signaling, physiology and pathology.; Signal transduction and targeted therapy; Vol 11(1), pp. 20. 2026 Jan 16.
1. Post CM
2. Agyemang JJ
3. McDonald KA
4. McDonough CA
5. Lawrence BP
Developmental exposure to a PFAS mixture impairs the anamnestic response to influenza A virus infection in mice.; bioRxiv : the preprint server for biology. 2025 Nov 12.
1. Liu J
2. Qiu Q
3. Klemens CA
4. Garimella V
5. Huang J
6. Perera NLD
7. McDonough CA
8. Post CM
9. Lawrence BP
10. Le TH
11. Li C
12. Liang M
13. Wu JO
Per- and Polyfluoroalkyl Substances Induces Salt-Sensitive Hypertension by Upregulating Epithelial Sodium Channel - The First Experimental Evidence Supporting Causality.; bioRxiv : the preprint server for biology. 2025 Sep 21.
1. Yee M
2. Misra R
3. Vesecky S
4. Barravecchia M
5. Najar RA
6. Rahman A
7. Pryhuber GS
8. Dean DA
9. Lawrence BP
10. Fisher D
11. O'Reilly MA
Ki-67 promotes inflammatory signaling governing neutrophil recruitment during respiratory infections.; EMBO molecular medicine. 2025 Jun 10.
1. Meléndez DC
2. Laniewski N
3. Jusko TA
4. Qiu X
5. Lawrence BP
6. Rivera-Núñez Z
7. Brunner J
8. Best M
9. Macomber A
10. Leger A
11. Kannan K
12. Miller RK
13. Barrett ES
14. O'Connor TG
15. Scheible K
In utero per - and polyfluoroalkyl substances (PFAS) exposure and changes in infant T helper cell development among UPSIDE-ECHO cohort participants.; Environmental health perspectives. 2025 Jun 09.
1. Haarmann-Stemmann T
2. Reichert D
3. Coumoul X
4. Lawrence BP
5. Perdew GH
6. Sherr DH
7. Weighardt H
8. Rolfes KM
9. Esser C
The Janus-facedness of the aryl hydrocarbon receptor pathway Report of the 6th International AHR Meeting: Research, Prevention, Therapy.; Biochemical pharmacology. 2025 Feb 19.
1. Sulentic CEW
2. Kaplan BLF
3. Lawrence BP
Using the Key Characteristics Framework to Unlock the Mysteries of Aryl Hydrocarbon Receptor-Mediated Effects on the Immune System.; Annual review of immunology. 2025 Jan 15.
1. Peng W
2. Chung KB
3. Lawrence BP
4. O'Banion MK
5. Dirksen RT
6. Wojtovich AP
7. Onukwufor JO
DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid β proteotoxicity.; Free radical biology & medicine. 2024 Sep 22.
1. Peng W
2. Chung KB
3. Lawrence BP
4. O'Banion MK
5. Dirksen RT
6. Wojtovich AP
7. Onukwufor JO
DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid β proteotoxicity.; bioRxiv : the preprint server for biology. 2024 Aug 09.
1. Post CM
2. McDonough C
3. Lawrence BP
Binary and quaternary mixtures of perfluoroalkyl substances (PFAS) differentially affect the immune response to influenza A virus infection.; Journal of immunotoxicology; Vol 21(1), pp. 2340495. 2024 Jul 01.
1. Houser CL
2. Fenner KN
3. Lawrence BP
Timing influences the impact of aryl hydrocarbon receptor activation on the humoral immune response to respiratory viral infection.; Toxicology and applied pharmacology. 2024 Jun 18.
1. Dorsey ER
2. Kinel D
3. Pawlik ME
4. Zafar M
5. Lettenberger SE
6. Coffey M
7. Auinger P
8. Hylton KL
9. Shaw CW
10. Adams JL
11. Barbano R
12. Braun MK
13. Schwarz HB
14. Lawrence BP
15. Kieburtz K
16. Tanner CM
17. de Miranda BR
18. Goldman SM
Dry-Cleaning Chemicals and a Cluster of Parkinson's Disease and Cancer: A Retrospective Investigation.; Movement disorders : official journal of the Movement Disorder Society. 2024 Feb 23.
1. Healey AM
2. Fenner KN
3. O'Dell CT
4. Lawrence BP
Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection.; American journal of physiology. Lung cellular and molecular physiology. 2024 Jan 30.
1. Kaplan BLF
2. Lawrence BP
Invited Perspective: Environmental Chemical-Sensing AHR Remains an Enigmatic Key Player in Toxicology.; Environmental health perspectives; Vol 131(3), pp. 31307. 2023 Mar 28.
1. Feiler MO
2. Yucel R
3. Liu Z
4. Caserta M
5. Lawrence BP
6. Pason CH
7. Hardy DJ
8. Thevenet-Morrison K
9. Dozier A
10. Jusko TA
Trends and Non-Clinical Predictors of Respiratory Syncytial Virus (RSV) and Influenza Diagnosis in an Urban Pediatric Population.; International journal of pediatric research; Vol 9(1). 2023 Mar 06.
1. Post CM
2. Myers JR
3. Winans B
4. Lawrence BP
Postnatal administration of S-adenosylmethionine restores developmental AHR activation-induced deficits in CD8+ T cell function during influenza A virus infection.; Toxicological sciences : an official journal of the Society of Toxicology. 2023 Feb 27.
1. McGraw MD
2. Yee M
3. Kim SY
4. Dylag AM
5. Lawrence BP
6. O'Reilly MA
Diacetyl Inhalation Impairs Airway Epithelial Repair in Mice Infected with Influenza A Virus.; American journal of physiology. Lung cellular and molecular physiology. 2022 Sep 06.
1. McCarthy CE
2. Duffney PF
3. Nogales A
4. Post CM
5. Lawrence BP
6. Martinez-Sobrido L
7. Thatcher TH
8. Phipps RP
9. Sime PJ
Dung biomass smoke exposure impairs resolution of inflammatory responses to influenza infection.; Toxicology and applied pharmacology. 2022 Jul 08.
1. Houser CL
2. Lawrence BP
The Aryl Hydrocarbon Receptor Modulates T Follicular Helper Cell Responses to Influenza Virus Infection in Mice.; Journal of immunology (Baltimore, Md. : 1950). 2022 Apr 20.
1. Germolec DR
2. Lebrec H
3. Anderson SE
4. Burleson GR
5. Cardenas A
6. Corsini E
7. Elmore SE
8. Kaplan BLF
9. Lawrence BP
10. Lehmann GM
11. Maier CC
12. McHale CM
13. Myers LP
14. Pallardy M
15. Rooney AA
16. Zeise L
17. Zhang L
18. Smith MT
Consensus on the Key Characteristics of Immunotoxic Agents as a Basis for Hazard Identification.; Environmental health perspectives; Vol 130(10), pp. 105001. 2022 Jan 06.
1. O'Dell CT
2. Boule LA
3. Robert J
4. Georas SN
5. Eliseeva S
6. Lawrence BP
Exposure to a mixture of 23 chemicals associated with unconventional oil and gas operations alters immune response to challenge in adult mice.; Journal of immunotoxicology; Vol 18(1). 2021 Dec.
1. Vaughan KL
2. Franchini AM
3. Kern HG
4. Lawrence BP
The aryl hydrocarbon receptor modulates murine hematopoietic stem cell homeostasis and influences lineage-biased stem and progenitor cells.; Stem cells and development. 2021 Aug 24.
1. McGuire CC
2. Lawrence BP
3. Robert J
Thyroid Disrupting Chemicals in mixture Perturb Thymocyte Differentiation in Xenopus laevis tadpoles.; Toxicological sciences : an official journal of the Society of Toxicology. 2021 Mar 03.
1. Burke CG
2. Myers JR
3. Post CM
4. Boulé LA
5. Lawrence BP
DNA Methylation Patterns in CD4+ T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Exposed to an Aryl Hydrocarbon Receptor Ligand.; Environmental health perspectives; Vol 129(1). 2021 Jan.
1. Aftabi Y
2. Rafei S
3. Zarredar H
4. Amiri-Sadeghan A
5. Akbari-Shahpar M
6. Khoshkam Z
7. Seyedrezazadeh E
8. Khalili M
9. Mehrnejad F
10. Fereidouni S
11. Lawrence BP
Refinement of coding SNPs in the human aryl hydrocarbon receptor gene using ISNPranker: An integrative-SNP ranking web-tool.; Computational biology and chemistry; Vol 90. 2020 Nov 17.
1. Feiler MO
2. Caserta MT
3. van Wijngaarden E
4. Thevenet-Morrison K
5. Hardy DJ
6. Zhang YV
7. Dozier AM
8. Lawrence BP
9. Jusko TA
Environmental Lead Exposure and Influenza and Respiratory Syncytial Virus Diagnoses in Young Children: A Test-Negative Case-Control Study.; International journal of environmental research and public health; Vol 17(20). 2020 Oct 19.
1. Nagel SC
2. Kassotis CD
3. Vandenberg LN
4. Lawrence BP
5. Robert J
6. Balise VD
Developmental exposure to a mixture of unconventional oil and gas chemicals: A review of effects on adult health, behavior, and disease.; Molecular and cellular endocrinology. 2020 Mar 02.
1. Post CM
2. Boule LA
3. Burke CG
4. O'Dell CT
5. Winans B
6. Lawrence BP
The Ancestral Environment Shapes Antiviral CD8+ T cell Responses across Generations.; iScience; Vol 20. 2019 Sep 14.
1. Jusko TA
2. Singh K
3. Greener EA
4. Oktapodas Feiler M
5. Thevenet-Morrison K
6. Lawrence BP
7. Wright RO
8. Thurston SW
Blood Lead Concentrations and Antibody Levels to Measles, Mumps, and Rubella among U.S. Children.; International journal of environmental research and public health; Vol 16(17). 2019 Aug 22.
1. Burke CG
2. Myers JR
3. Boule LA
4. Post CM
5. Brookes PS
6. Lawrence BP
Early life exposures shape the CD4+ T cell transcriptome, influencing proliferation, differentiation, and mitochondrial dynamics later in life.; Scientific reports; Vol 9(1). 2019 Aug 07.
1. Franchini AM
2. Myers JR
3. Jin GB
4. Shepherd DM
5. Lawrence BP
Genome-Wide Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function during Influenza A Virus Infection.; ImmunoHorizons; Vol 3(6). 2019 Jun 17.
1. Robert J
2. McGuire CC
3. Nagel S
4. Lawrence BP
5. Andino FJ
Developmental exposure to chemicals associated with unconventional oil and gas extraction alters immune homeostasis and viral immunity of the amphibian Xenopus.; The Science of the total environment; Vol 671. 2019 Mar 26.
1. Esser C
2. Lawrence BP
3. Sherr DH
4. Perdew GH
5. Puga A
6. Barouki R
7. Coumoul X
Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29⁻31 August 2018 in Paris, France.; International journal of molecular sciences; Vol 19(11). 2018 Nov 15.
1. Franchini AM
2. Lawrence BP
Environmental exposures are hidden modifiers of anti-viral immunity.; Current opinion in toxicology; Vol 10. 2018 Aug.
1. Robert J
2. McGuire CC
3. Kim F
4. Nagel SC
5. Price SJ
6. Lawrence BP
7. De Jesús Andino F
Water contaminants associated with unconventional oil and gas extraction cause immunotoxicity to amphibian tadpoles.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 Jul 11.
1. Boulé LA
2. Chapman TJ
3. Hillman SE
4. Kassotis CD
5. O'Dell C
6. Robert J
7. Georas SN
8. Nagel SC
9. Lawrence BP
Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 May 01.
1. Boule LA
2. Burke CG
3. Jin GB
4. Lawrence BP
Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome.; Scientific reports; Vol 8(1). 2018 Jan 29.
1. Meyers JL
2. Winans B
3. Kelsaw E
4. Murthy A
5. Gerber S
6. Lawrence BP
Environmental cues received during development shape dendritic cell responses later in life.; PloS one; Vol 13(11). 2018.
1. Bennett JA
2. Singh KP
3. Welle SL
4. Boule LA
5. Lawrence BP
6. Gasiewicz TA
Conditional deletion of Ahr alters gene expression profiles in hematopoietic stem cells.; PloS one; Vol 13(11). 2018.
1. Yee M
2. Domm W
3. Gelein R
4. Bentley KL
5. Kottmann RM
6. Sime PJ
7. Lawrence BP
8. O'Reilly MA
Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.; American journal of respiratory cell and molecular biology; Vol 56(4). 2017 Apr.
1. De Jesús Andino F
2. Lawrence BP
3. Robert J
Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis.; Chemosphere; Vol 170. 2017 Mar.
1. Hessel EV
2. Ezendam J
3. Broekhuizen FA
4. Hakkert B
5. DeWitt J
6. Granum B
7. Guzylack L
8. Lawrence BP
9. Penninks A
10. Rooney AA
11. Piersma AH
12. Loveren HV
Assessment of recent developmental immunotoxicity studies with bisphenol A in the context of the 2015 EFSA t-TDI.; Reproductive toxicology (Elmsford, N.Y.). 2016 Jun 25.
1. Jusko TA
2. De Roos AJ
3. Lee SY
4. Thevenet-Morrison K
5. Schwartz SM
6. Verner MA
7. Murinova LP
8. Drobná B
9. Kočan A
10. Fabišiková A
11. Čonka K
12. Trnovec T
13. Hertz-Picciotto I
14. Lawrence BP
A Birth Cohort Study of Maternal and Infant Serum PCB-153 and DDE Concentrations and Responses to Infant Tuberculosis Vaccination.; Environmental health perspectives; Vol 124(6). 2016 Jun.
1. Jusko T
2. Oktapodas M
3. Palkovičová Murinová Ľ
4. Babinska K
5. Babjakova J
6. Verner MA
7. DeWitt J
8. Thevenet-Morrison K
9. Conka K
10. Drobná B
11. Chovancova J
12. Thurston S
13. Lawrence BP
14. Dozier A
15. Jarvinen K
16. Patayova H
17. Trnovec T
18. Legler J
19. Hertz-Picciotto I
20. Lamoree MH
Demographic, reproductive, and dietary determinants of perfluorooctane sulfonic (PFOS) and perfluorooctanoic acid (PFOA) concentrations in human colostrum.; Environmental science & technology. 2016 May 31.
1. Yee M
2. Gelein R
3. Mariani TJ
4. Lawrence BP
5. O'Reilly MA
The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung.; Stem cells (Dayton, Ohio); Vol 34(5). 2016 May.
1. Boule LA
2. Burke CG
3. Fenton BM
4. Thevenet-Morrison K
5. Jusko TA
6. Lawrence BP
Developmental Activation of the AHR Increases Effector CD4+ T Cells and Exacerbates Symptoms in Autoimmune Disease-Prone Gnaq+/- Mice.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 148(2). 2015 Dec.
1. Boule LA
2. Winans B
3. Lambert K
4. Vorderstrasse BA
5. Topham DJ
6. Pavelka MS
7. Lawrence BP
Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(3). 2015 Aug 1.
1. Winans B
2. Nagari A
3. Chae M
4. Post CM
5. Ko CI
6. Puga A
7. Kraus WL
8. Lawrence BP
Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.; Journal of immunology (Baltimore, Md. : 1950); Vol 194(9). 2015 May 1.
1. Sundar IK
2. Ahmad T
3. Yao H
4. Hwang JW
5. Gerloff J
6. Lawrence BP
7. Sellix MT
8. Rahman I
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.; Scientific reports; Vol 4. 2015.