URMC / Labs / Lawrence Lab / Publications Publications Boule LABurke CGJin GBLawrence BP Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome.; Scientific reports; Vol 81. 2018 Jan 29. Yee MDomm WGelein RBentley KLKottmann RMSime PJLawrence BPO'Reilly MA Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.; American journal of respiratory cell and molecular biology; Vol 564. 2017 Apr. De Jesús Andino FLawrence BPRobert J Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis.; Chemosphere; Vol 170. 2017 Mar. Hessel EVEzendam JBroekhuizen FAHakkert BDeWitt JGranum BGuzylack LLawrence BPPenninks ARooney AAPiersma AHLoveren HV Assessment of recent developmental immunotoxicity studies with bisphenol A in the context of the 2015 EFSA t-TDI.; Reproductive toxicology (Elmsford, N.Y.). 2016 Jun 25. Jusko TADe Roos AJLee SYThevenet-Morrison KSchwartz SMVerner MAMurinova LPDrobná BKočan AFabišiková AČonka KTrnovec THertz-Picciotto ILawrence BP A Birth Cohort Study of Maternal and Infant Serum PCB-153 and DDE Concentrations and Responses to Infant Tuberculosis Vaccination.; Environmental health perspectives; Vol 1246. 2016 Jun. Jusko TOktapodas MPalkovičová Murinová ĽBabinska KBabjakova JVerner MADeWitt JThevenet-Morrison KConka KDrobná BChovancova JThurston SLawrence BPDozier AJarvinen KPatayova HTrnovec TLegler JHertz-Picciotto ILamoree MH Demographic, reproductive, and dietary determinants of perfluorooctane sulfonic (PFOS) and perfluorooctanoic acid (PFOA) concentrations in human colostrum.; Environmental science & technology. 2016 May 31. Yee MGelein RMariani TJLawrence BPO'Reilly MA The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung.; Stem cells (Dayton, Ohio); Vol 345. 2016 May. Boule LABurke CGFenton BMThevenet-Morrison KJusko TALawrence BP Developmental Activation of the AHR Increases Effector CD4+ T Cells and Exacerbates Symptoms in Autoimmune Disease-Prone Gnaq+/- Mice.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1482. 2015 Dec. Boule LAWinans BLambert KVorderstrasse BATopham DJPavelka MSLawrence BP Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 3093. 2015 Aug 1. Winans BNagari AChae MPost CMKo CIPuga AKraus WLLawrence BP Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.; Journal of immunology (Baltimore, Md. : 1950); Vol 1949. 2015 May 1. Reilly ECMartin KCJin GBYee MO'Reilly MALawrence BP Neonatal hyperoxia leads to persistent alterations in NK responses to influenza A virus infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 3081. 2015 Jan 1. Sundar IKAhmad TYao HHwang JWGerloff JLawrence BPSellix MTRahman I Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.; Scientific reports; Vol 4. 2015. Sobolewski MConrad KAllen JLWeston HMartin KLawrence BPCory-Slechta DA Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals.; Neurotoxicology; Vol 45. 2014 Dec. Sifkarovski JGrayfer LDe Jesús Andino FLawrence BPRobert J Negative effects of low dose atrazine exposure on the development of effective immunity to FV3 in Xenopus laevis.; Developmental and comparative immunology; Vol 471. 2014 Nov. Boule LAWinans BLawrence BP Effects of developmental activation of the AhR on CD4+ T-cell responses to influenza virus infection in adult mice.; Environmental health perspectives; Vol 12211. 2014 Nov. Jin GBWinans BMartin KCLawrence BP New insights into the role of the aryl hydrocarbon receptor in the function of CD11c⁺ cells during respiratory viral infection.; European journal of immunology; Vol 446. 2014 Jun. Maduekwe ETBuczynski BWYee MRangasamy TStevens TPLawrence BPO'Reilly MA Cumulative neonatal oxygen exposure predicts response of adult mice infected with influenza A virus.; Pediatric pulmonology. 2014 May 22. Regal JFLawrence BPJohnson ACLojovich SJO'Reilly MA Neonatal oxygen exposure alters airway hyper-responsiveness but not the response to allergen challenge in adult mice.; Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology; Vol 252. 2014 Mar. Wheeler JLMartin KCResseguie ELawrence BP Differential consequences of two distinct AhR ligands on innate and adaptive immune responses to influenza A virus.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1372. 2014 Feb. Lawrence BPVorderstrasse BA New insights into the aryl hydrocarbon receptor as a modulator of host responses to infection.; Seminars in immunopathology; Vol 356. 2013 Nov. Roy AGaylo ACao WSaubermann LJLawrence BP Neither direct nor developmental exposure to bisphenol A alters the severity of experimental inflammatory colitis in mice.; Journal of immunotoxicology; Vol 104. 2013 Oct. Buczynski BWYee MMartin KCLawrence BPO'Reilly MA Neonatal hyperoxia alters the host response to influenza A virus infection in adult mice through multiple pathways.; American journal of physiology. Lung cellular and molecular physiology; Vol 3054. 2013 Aug 15. Manning CMJohnston CJHernady EMiller JNReed CKLawrence BPWilliams JPFinkelstein JN Exacerbation of lung radiation injury by viral infection: the role of Clara cells and Clara cell secretory protein.; Radiation research; Vol 1796. 2013 Jun. Manning CMJohnston CJReed CKLawrence BPWilliams JPFinkelstein JN Lung irradiation increases mortality after influenza A virus challenge occurring late after exposure.; International journal of radiation oncology, biology, physics; Vol 861. 2013 May 1. Yee MBuczynski BWLawrence BPO'Reilly MA Neonatal hyperoxia increases sensitivity of adult mice to bleomycin-induced lung fibrosis.; American journal of respiratory cell and molecular biology; Vol 482. 2013 Feb. Wheeler JLMartin KCLawrence BP Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection.; Journal of immunology (Baltimore, Md. : 1950); Vol 1902. 2013 Jan 15. Bauer SMRoy AEmo JChapman TJGeoras SNLawrence BP The effects of maternal exposure to bisphenol A on allergic lung inflammation into adulthood.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1301. 2012 Nov. McKarns SCKerkvliet NIDean JHBonn MBCohen MDFranko JLaiosa MDLawrence BPLuebke RWLuster MIMiller PGPalmer RKPfau JCRaman PRegal JFRodgers KESchondelmeyer RSZhang XBurns-Naas LA Immunotoxicology: fifty years of global scientific progress.; Journal of immunotoxicology; Vol 94. 2012 Oct. Giannandrea MYee MO'Reilly MALawrence BP Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation.; Clinical and vaccine immunology : CVI; Vol 199. 2012 Sep. O'Reilly MAYee MBuczynski BWVitiello PFKeng PCWelle SLFinkelstein JNDean DALawrence BP Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1.; The American journal of pathology; Vol 1812. 2012 Aug. Buczynski BWYee MPaige Lawrence BO'Reilly MA Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice.; American journal of physiology. Lung cellular and molecular physiology; Vol 30210. 2012 May 15. Lawrence BPSherr DH You AhR what you eat?; Nature immunology; Vol 132. 2012 Feb. Roy ABauer SMLawrence BP Developmental exposure to bisphenol A modulates innate but not adaptive immune responses to influenza A virus infection.; PloS one; Vol 76. 2012. Lew BJManickam RLawrence BP Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters mammary development through direct effects on stromal and epithelial tissues.; Biology of reproduction; Vol 846. 2011 Jun. Wang TGavin HMArlt VMLawrence BPFenton SEMedina DVorderstrasse BA Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors.; International journal of cancer; Vol 1287. 2011 Apr 1. Winans BHumble MCLawrence BP Environmental toxicants and the developing immune system: a missing link in the global battle against infectious disease?; Reproductive toxicology (Elmsford, N.Y.); Vol 313. 2011 Apr. Jusko TADe Roos AJSchwartz SMLawrence BPPalkovicova LNemessanyi TDrobna BFabisikova AKocan AJahnova EKavanagh TJTrnovec THertz-Picciotto I Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants.; Journal of immunotoxicology; Vol 81. 2011 Jan. Jin GBMoore AJHead JLNeumiller JJLawrence BP Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1162. 2010 Aug. Jusko TADe Roos AJSchwartz SMLawrence BPPalkovicova LNemessanyi TDrobna BFabisikova AKocan ASonneborn DJahnova EKavanagh TJTrnovec THertz-Picciotto I A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age.; Environmental research; Vol 1104. 2010 May. Lew BJCollins LLO'Reilly MALawrence BP Activation of the aryl hydrocarbon receptor during different critical windows in pregnancy alters mammary epithelial cell proliferation and differentiation.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1111. 2009 Sep. Collins LLLew BJLawrence BP TCDD exposure disrupts mammary epithelial cell differentiation and function.; Reproductive toxicology (Elmsford, N.Y.); Vol 281. 2009 Jul. Head JLLawrence BP The aryl hydrocarbon receptor is a modulator of anti-viral immunity.; Biochemical pharmacology; Vol 774. 2009 Feb 15. Lawrence BPDenison MSNovak HVorderstrasse BAHarrer NNeruda WReichel CWoisetschläger M Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound.; Blood; Vol 1124. 2008 Aug 15. O'Reilly MAMarr SHYee MMcGrath-Morrow SALawrence BP Neonatal hyperoxia enhances the inflammatory response in adult mice infected with influenza A virus.; American journal of respiratory and critical care medicine; Vol 17710. 2008 May 15. Teske SBohn AAHogaboam JPLawrence BP Aryl hydrocarbon receptor targets pathways extrinsic to bone marrow cells to enhance neutrophil recruitment during influenza virus infection.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1021. 2008 Mar. Hogaboam JPMoore AJLawrence BP The aryl hydrocarbon receptor affects distinct tissue compartments during ontogeny of the immune system.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 1021. 2008 Mar. Neff-LaFord HTeske SBushnell TPLawrence BP Aryl hydrocarbon receptor activation during influenza virus infection unveils a novel pathway of IFN-gamma production by phagocytic cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 1791. 2007 Jul 1. Lawrence BP Environmental toxins as modulators of antiviral immune responses.; Viral immunology; Vol 202. 2007. Lawrence BPRoberts ADNeumiller JJCundiff JAWoodland DL Aryl hydrocarbon receptor activation impairs the priming but not the recall of influenza virus-specific CD8+ T cells in the lung.; Journal of immunology (Baltimore, Md. : 1950); Vol 1779. 2006 Nov 1. Vorderstrasse BALawrence BP Protection against lethal challenge with Streptococcus pneumoniae is conferred by aryl hydrocarbon receptor activation but is not associated with an enhanced inflammatory response.; Infection and immunity; Vol 7410. 2006 Oct.