Publications
Publications
- Improving SBRT by re-wiring immunosuppressive neutrophils in murine pancreatic ductal adenocarcinoma.; International journal of radiation oncology, biology, physics. 2025 Jul 01.
- Blockade of LIF and PD-L1 Enhances Chemotherapy in Preclinical PDAC Models.; Cancers; Vol 17(2). 2025 Jan 09.
- Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.; Molecular therapy. Nucleic acids; Vol 35(4), pp. 102350. 2024 Sep 30.
- New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy.; Cell death & disease; Vol 14(7), pp. 470. 2023 Jul 26.
- CD73 and PD-L1 dual blockade amplifies antitumor efficacy of SBRT in murine PDAC models.; Journal for immunotherapy of cancer; Vol 11(5). 2023 May.
- Combination of NKG2A and PD-1 Blockade Improves Radiotherapy Response in Radioresistant Tumors.; Journal of immunology (Baltimore, Md. : 1950). 2022 Jul 15.
- Toll-like receptor 7/8 agonist R848 alters the immune tumor microenvironment and enhances SBRT-induced antitumor efficacy in murine models of pancreatic cancer.; Journal for immunotherapy of cancer; Vol 10(7). 2022 Jul.
- Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.; International journal of molecular sciences; Vol 23(6). 2022 Mar 08.
- Development of an Orthotopic Murine Model of Rectal Cancer in Conjunction With Targeted Short-Course Radiation Therapy.; Advances in radiation oncology; Vol 7(2). 2022 Mar.
- Radiotherapy exacerbates tumor-promoting innervation and nerve signaling in rectal cancer.; International journal of radiation oncology, biology, physics. 2022 Jan 03.
- Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model.; Cancers; Vol 13(10). 2021 May 11.
- Co-administration of a clinically relevant dexamethasone dosage with ablative radiotherapy reduces peripheral lymphocytes but does not alter in vivo intratumoral lymphocyte phenotype or inhibit efficacy of radiotherapy in a murine colorectal tumor model.; International journal of radiation oncology, biology, physics. 2021 Apr 29.
- Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.; Immunological investigations. 2020 Jun 04.
- Assessing the magnitude of immunogenic cell death following chemotherapy and irradiation reveals a new strategy to treat pancreatic cancer.; Cancer immunology research. 2019 Nov 12.
- Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment.; Cell reports; Vol 29(2). 2019 Oct 08.
- Intratumoral Hypoxia Reduces IFN-γ-Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model.; ImmunoHorizons; Vol 3(4). 2019 Apr 29.
- Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation.; Radiation research. 2019 Apr 25.
- Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes.; Oncotarget. 2016 Nov 11.
- Total-Body Irradiation Exacerbates Dissemination of Cutaneous Candida Albicans Infection.; Radiation research. 2016 Oct 6.
- Whole mount immunofluorescence analysis of placentas from normotensive versus preeclamptic pregnancies.; Placenta; Vol 36(11). 2015 Nov.
- Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure.; Radiation research; Vol 183(1). 2015 Jan.
- Differential growth inhibition of cerebral metastases by anti-angiogenic compounds.; Anticancer research; Vol 34(7). 2014 Jul.
- Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors.; International journal of cancer; Vol 134(10). 2014 May 15.
- Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence.; Biology of reproduction; Vol 90(5). 2014 May.
- Optogenetic control of chemokine receptor signal and T-cell migration.; Proceedings of the National Academy of Sciences of the United States of America; Vol 111(17). 2014 Apr 29.
- Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells.; Cancer immunology, immunotherapy : CII; Vol 63(3). 2014 Mar.
- G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation.; Arteriosclerosis, thrombosis, and vascular biology; Vol 34(2). 2014 Feb.
- Radiation therapy combined with Listeria monocytogenes-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model.; Oncoimmunology; Vol 3. 2014.
- Generation of a dual-functioning antitumor immune response in the peritoneal cavity.; The American journal of pathology; Vol 183(4). 2013 Oct.
- IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumor.; The American journal of pathology; Vol 182(6). 2013 Jun.
- Local expression of interleukin-2 by B16 melanoma cells results in decreased tumour growth and long-term tumour dormancy.; Immunology; Vol 138(3). 2013 Mar.
- Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism.; Journal of immunology (Baltimore, Md. : 1950); Vol 189(9). 2012 Nov 01.
- A broadly applicable approach to T cell epitope identification: application to improving tumor associated epitopes and identifying epitopes in complex pathogens.; Journal of immunological methods; Vol 373(1-2). 2011 Oct 28.
- IL-12 suppresses vascular endothelial growth factor receptor 3 expression on tumor vessels by two distinct IFN-gamma-dependent mechanisms.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(4). 2010 Feb 15.
- Immunology at the university of Rochester.; Immunologic research; Vol 45(2-3). 2009 Dec.
- Omental immune aggregates and tumor metastasis within the peritoneal cavity.; Immunologic research; Vol 45(2-3). 2009 Dec.
- Migration of skin dendritic cells in response to ionizing radiation exposure.; Radiation research; Vol 171(6). 2009 Jun.
- Antibody-labeled fluorescence imaging of dendritic cell populations in vivo.; Journal of biomedical optics; Vol 13(4). 2008 Jul.
- Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity.; Journal of immunology (Baltimore, Md. : 1950); Vol 180(5). 2008 Mar 1.
- Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors.; Human gene therapy; Vol 18(2). 2007 Feb.
- In vivo study of T-cell responses to skin alloantigens in Xenopus using a novel whole-mount immunohistology method.; Transplantation; Vol 83(2). 2007 Jan 27.
- Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth.; The American journal of pathology; Vol 169(5). 2006 Nov.
- Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor.; Journal of immunology (Baltimore, Md. : 1950); Vol 174(12). 2005 Jun 15.
- Characterization of a lymph node within the mouse prostate: Detailed analysis using whole mount histology.; The Prostate; Vol 63(2). 2005 May 1.
- Transfection of the genes for interleukin-12 into the K1735 melanoma and the EMT6 mammary sarcoma murine cell lines reveals distinct mechanisms of antitumor activity.; International journal of cancer; Vol 106(5). 2003 Sep 20.
- Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts.; British journal of cancer; Vol 88(9). 2003 May 6.
- Generation of monoclonal antibodies specific for human kallikrein 2 (hK2) using hK2-expressing tumors.; The Prostate; Vol 51(3). 2002 May 15.
- Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice.; Human gene therapy; Vol 12(15). 2001 Oct 10.
- T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes.; Journal of immunological methods; Vol 256(1-2). 2001 Oct 1.
- Intravascular HBO(2) saturations, perfusion and hypoxia in spontaneous and transplanted tumor models.; International journal of cancer; Vol 93(5). 2001 Sep 1.
- Tumours can act as adjuvants for humoral immunity.; Immunology; Vol 102(4). 2001 Apr.
- Effects of radiation on tumor intravascular oxygenation, vascular configuration, development of hypoxia, and clonogenic survival.; Radiation research; Vol 155(2). 2001 Feb.
- Alteration of tumour response to radiation by interleukin-2 gene transfer.; British journal of cancer; Vol 82(4). 2000 Feb.
- Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation.; Radiation research; Vol 153(1). 2000 Jan.
- Interleukin-3 and granulocyte-macrophage colony-stimulating factor enhance the generation and function of dendritic cells.; Immunology; Vol 97(1). 1999 May.
- Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements.; British journal of cancer; Vol 79(3-4). 1999 Feb.
- Regulation of human prostate-specific antigen gene expression in transgenic mice: evidence for an enhancer between the PSA and human glandular kallikrein-1 genes.; International journal of molecular medicine; Vol 2(4). 1998 Oct.
- IL-3 enhances both presentation of exogenous particulate antigen in association with class I major histocompatibility antigen and generation of primary tumor-specific cytolytic T lymphocytes.; Journal of immunology (Baltimore, Md. : 1950); Vol 160(12). 1998 Jun 15.
- IL-3-mediated enhancement of particulate antigen presentation by macrophages.; Journal of immunotherapy (Hagerstown, Md. : 1997); Vol 21(3). 1998 May.
- Tumor immunotherapy: cytokines and antigen presentation.; Cancer immunology, immunotherapy : CII; Vol 46(2). 1998 Apr.
- Interleukin 2 expression by tumor cells alters both the immune response and the tumor microenvironment.; Cancer research; Vol 58(7). 1998 Apr 1.
- A transgenic strategy for analyzing the regulatory regions of the human prostate-specific antigen gene: potential applications for the treatment of prostate cancer (Review).; International journal of molecular medicine; Vol 1(2). 1998 Feb.
- Effect of local irradiation on tumor oxygenation, perfused vessel density, and development of hypoxia.; Advances in experimental medicine and biology; Vol 454. 1998.
- Expression of B7-1 by Pam 212 squamous cell carcinoma enhances tumor cell interactions with dendritic epidermal cells but does not affect in vivo tumor growth.; The Journal of investigative dermatology; Vol 109(6). 1997 Dec.
- Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy.; Proceedings of the National Academy of Sciences of the United States of America; Vol 94(12). 1997 Jun 10.
- Imaging hypoxia and blood flow in normal tissues.; Advances in experimental medicine and biology; Vol 428. 1997.
- Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts.; International journal of cancer; Vol 67(3). 1996 Jul 29.
- Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes.; Cancer immunology, immunotherapy : CII; Vol 42(6). 1996 Jul.
- Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogenous antigen by tumor-infiltrating antigen-presenting cells.; Proceedings of the National Academy of Sciences of the United States of America; Vol 93(8). 1996 Apr 16.
- Detection of individual hypoxic cells in multicellular spheroids by flow cytometry using the 2-nitroimidazole, EF5, and monoclonal antibodies.; International journal of radiation oncology, biology, physics; Vol 34(1). 1996 Jan 1.
- Analysis of the effect of cytokines (interleukins 2, 3, 4, and 6, granulocyte-monocyte colony-stimulating factor, and interferon-gamma) on generation of primary cytotoxic T lymphocytes against a weakly immunogenic tumor.; Cellular immunology; Vol 165(2). 1995 Oct 15.
- B7-1 enhances natural killer cell-mediated cytotoxicity and inhibits tumor growth of a poorly immunogenic murine carcinoma.; Cellular immunology; Vol 165(2). 1995 Oct 15.
- Synergistic effects of co-expression of the TH1 cytokines IL-2 and IFN-gamma on generation of murine tumor-reactive cytotoxic cells.; International journal of cancer; Vol 61(5). 1995 May 29.
- Transfection of transforming growth factor-beta producing tumor EMT6 with interleukin-2 elicits tumor rejection and tumor reactive cytotoxic T-lymphocytes.; Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy; Vol 15(3). 1994 Apr.
- Isolation and expansion of tumor-infiltrating lymphocytes.; BioTechniques; Vol 15(6). 1993 Dec.
- Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts.; Cancer research; Vol 53(23). 1993 Dec 1.
- Interleukin-3 inhibits the generation of nonspecific killers by interleukin-2.; Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy; Vol 14(4). 1993 Nov.
- Murine Pam 212 cutaneous squamous cell carcinoma is nonimmunogenic in normal syngeneic hosts and resistant to immune effector mechanisms.; Regional immunology; Vol 5(5). 1993 Sep.
- Interleukin 3 enhances development of tumor-reactive cytotoxic cells by a CD4-dependent mechanism.; Cancer research; Vol 53(9). 1993 May 1.
- CD4-class II major histocompatibility complex interaction does not enhance killing by a class I-restricted CD4+CD8+ cytotoxic T cell clone.; European journal of immunology; Vol 22(9). 1992 Sep.
- Two regions of the H-2 Dd promoter are responsive to dimethylsulfoxide in line 1 cells by a mechanism distinct from IFN-gamma.; Journal of immunology (Baltimore, Md. : 1950); Vol 148(4). 1992 Feb 15.
- Mechanism of cytolytic T lymphocyte killing of a low class I-expressing tumor.; Journal of immunology (Baltimore, Md. : 1950); Vol 147(4). 1991 Aug 15.
- Class-I MHC expression in the mouse lung carcinoma, line 1: a model for class-I inducible tumors.; International journal of cancer. Supplement = Journal international du cancer. Supplement; Vol 6. 1991.
- Alteration of the metastatic potential of line 1 lung carcinoma cells: opposite effects of class I antigen induction by interferons versus DMSO or gene transfection.; Cellular immunology; Vol 127(2). 1990 May.
- Tumor necrosis factor-mediated cytotoxicity by tumor-associated macrophages.; Cellular immunology; Vol 123(1). 1989 Oct 1.
- Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle.; Biochemistry; Vol 28(7). 1989 Apr 4.
- Molecular analysis of deficient class I H-2 antigen expression by mouse lung carcinoma cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 140(11). 1988 Jun 1.
- Cell cycle dependent activities of DNA polymerases alpha and delta in Chinese hamster ovary cells.; Biochemistry; Vol 26(24). 1987 Dec 1.
- Comparison of fluorescence intensity of Hoechst 33342-stained EMT6 tumour cells and tumour-infiltrating host cells.; British journal of cancer; Vol 56(5). 1987 Nov.