URochester Medicine / Labs / McGrath Lab / Publications

Recent Publications

1. Widom LP
2. Torabian P
3. Trempel MA
4. McCloskey MC
5. Michel LV
6. McGrath JL
7. Gaborski TR
Bacterial extracellular vesicles indirectly destabilize a human stem cell-derived blood-brain barrier on-chip through pro-inflammatory stimulation of immune cells.; Lab on a chip. 2026 Apr 14.
1. Linares I
2. Creveling A
3. Osman A
4. Grandwetter N
5. Miller BL
6. McGrath JL
7. Awad HA
A human synovial tendon-on-a-chip models key features of peritendinous adhesions and offers a new approach methodology for testing anti-fibrotic drugs.; bioRxiv : the preprint server for biology. 2026 Apr 07.
1. Zhang VZ
2. Elias T
3. Rodriguez M
4. Abbondanzieri E
5. Brown E
6. McGrath JL
7. Awad HA
Type III Collagen Promotes a Pro-Fibrotic Microenvironment for In Vitro Tendon Healing Microphysiological Systems.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 44(4), pp. e70192. 2026 Apr.
1. Chiang W
2. Li H
3. Le L
4. David-Bercholz J
5. Caceres AI
6. Ahmad D
7. Squire E
8. Stecyk KS
9. Marrero M
10. Pereira A
11. Squire R
12. Lim C
13. McGrath JL
14. Majewska AK
15. Terrando N
16. Gelbard HA
Dynamics of neutrophilia at the neurovascular unit arising from repeated pulmonary inflammation.; Journal of neuroinflammation. 2026 Mar 25.
1. Farajollahi S
2. Mansouri M
3. De Silva D
4. Hsu MC
5. Chen K
6. Hughes A
7. Esmaili P
8. Goyal K
9. Day SW
10. McGrath JL
11. Abhyankar VV
Modular Integration of Impedance Sensing for Real-Time Assessment of Barrier Integrity.; bioRxiv : the preprint server for biology. 2026 Mar 10.
1. Widom LP
2. Torabian P
3. Trempel MA
4. McCloskey MC
5. Michel LV
6. McGrath JL
7. Gaborski TR
Bacterial extracellular vesicles indirectly destabilize a human stem cell-derived blood-brain barrier on-chip through pro-inflammatory stimulation of immune cells.; bioRxiv : the preprint server for biology. 2026 Jan 26.
1. Trempel MA
2. Du Y
3. Widom LP
4. Reitz EE
5. Feidler AM
6. Kasap P
7. Engelhardt B
8. Gaborski TR
9. Gelbard HA
10. Terrando N
11. McGrath JL
Pericytes repair engineered defects in the basement membrane to restore barrier integrity in an in vitro model of the blood-brain barrier.; Materials today. Bio; Vol 35, pp. 102361. 2025 Sep 26.
1. Chen K
2. Linares IM
3. Trempel MA
4. Feidler AM
5. De Silva D
6. Farajollahi S
7. Jones J
8. Kuebel J
9. Kasap P
10. Engelhardt B
11. Flax J
12. Abhyankar VV
13. Waugh RE
14. Gelbard HA
15. Terrando N
16. McGrath JL
Shear Conditioning Promotes Microvascular Endothelial Barrier Resilience in a Human BBB-on-a-Chip Model of Systemic Inflammation Leading to Astrogliosis.; Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2025 Aug 27.
1. Trempel MA
2. Du Y
3. Widom LP
4. Reitz EE
5. Feidler AM
6. Kasap P
7. Engelhardt B
8. Gaborski TR
9. Gelbard HA
10. Terrando N
11. McGrath JL
Pericytes Repair Engineered Defects in the Basement Membrane to Restore Barrier Integrity in an in vitro Model of the Blood-Brain Barrier.; bioRxiv : the preprint server for biology. 2025 Jun 26.
1. Gaelen JI
2. Joseph J
3. Froyshteter AB
4. Gangopadhyay N
5. McGrath JL
6. Cheon EC
Risk Analysis of Unplanned Extubation and Inadvertent Endobronchial Intubation During Pediatric Cleft Palate and Lip Repair.; Paediatric anaesthesia. 2025 May 03.
1. Allison SG
2. Soltani H
3. Sethia R
4. McGrath JL
5. Rastatter JC
6. Yamada A
Multidisciplinary Management of an Anterior Skull Base Teratoma in a Neonate.; Plastic and reconstructive surgery. Global open; Vol 13(3), pp. e6604. 2025 Mar 12.
1. Linares I
2. Chen K
3. Saffren A
4. Mansouri M
5. Abhyankar VV
6. Miller BL
7. Begolo S
8. Awad HA
9. McGrath JL
Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis.; Scientific reports; Vol 15(1), pp. 3227. 2025 Jan 25.
1. Ajalik RE
2. Linares I
3. Alenchery RG
4. Zhang VZ
5. Wright TW
6. Miller BL
7. McGrath JL
8. Awad HA
Human Tendon-on-a-Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis.; Advanced healthcare materials. 2024 Nov 15.
1. McCloskey MC
2. Ahmad SD
3. Widom LP
4. Kasap P
5. Gastfriend BD
6. Shusta EV
7. Palecek SP
8. Engelhardt B
9. Gaborski TR
10. Flax J
11. Waugh RE
12. McGrath JL
Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood-Brain Barrier.; Biomaterials research; Vol 28, pp. 0081. 2024 Oct 03.
1. Walker SN
2. Lucas K
3. Dewey MJ
4. Badylak SF
5. Hussey GS
6. Flax J
7. McGrath JL
Rapid Assessment of Biomarkers on Single Extracellular Vesicles Using "Catch and Display" on Ultrathin Nanoporous Silicon Nitride Membranes.; Small (Weinheim an der Bergstrasse, Germany). 2024 Oct 02.
1. Cai B
2. De Jesus Andino F
3. McGrath JL
4. Romanick SS
5. Robert J
Ingestion of polyethylene terephthalate microplastic water contaminants by Xenopus laevis tadpoles negatively affects their resistance to ranavirus infection and antiviral immunity.; Environmental pollution (Barking, Essex : 1987); Vol 356, pp. 124340. 2024 Jun 06.
1. Walker SN
2. Lucas K
3. Dewey MJ
4. Badylak S
5. Hussey G
6. Flax J
7. McGrath JL
Rapid Assessment of Biomarkers on Single Extracellular Vesicles Using 'Catch and Display' on Ultrathin Nanoporous Silicon Nitride Membranes.; bioRxiv : the preprint server for biology. 2024 May 02.
1. Ahmad SD
2. Linares I
3. Pietropaoli A
4. Waugh RE
5. McGrath JL
Sided Stimulation of Endothelial Cells Modulates Neutrophil Trafficking in an in vitro Sepsis Model.; Advanced healthcare materials. 2024 Mar 28.
1. Mansouri M
2. Hughes AR
3. Audi LA
4. Carter AE
5. Vidas JA
6. McGrath JL
7. Abhyankar VV
Transforming Static Barrier Tissue Models into Dynamic Microphysiological Systems.; Journal of visualized experiments : JoVE. 2024 Feb 16.
1. McCloskey MC
2. Kasap P
3. Trempel M
4. Widom LP
5. Kuebel J
6. Chen K
7. Gaborski TR
8. Engelhardt B
9. McGrath JL
Use of the MicroSiM (µSiM) Barrier Tissue Platform for Modeling the Blood-Brain Barrier.; Journal of visualized experiments : JoVE. 2024 Jan 12.
1. McGrath JL
2. Mantilla-Rivas E
3. Aivaz M
4. Manrique M
5. Rana MS
6. Crowder HR
7. Oh NS
8. Rogers GF
9. Oh AK
Predicting Failure of Conservative Airway Management in Infants with Robin Sequence: The EARN Factors.; The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 2024 Jan 02.
1. McGrath JL
2. Reynolds MS
Recognizing and Responding to Patients with Personality Disorders.; Emergency medicine clinics of North America; Vol 42(1), pp. 125-134. 2023 Jul 31.
1. Rogers AE
2. Mantilla-Rivas E
3. Duarte-Bateman D
4. Manrique M
5. McGrath JL
6. Sohel Rana M
7. Oh AK
8. David LR
9. Janis JE
10. Rogers GF
Prevalence of Prohibited Questions during Plastic Surgery Residency Interviews.; Plastic and reconstructive surgery. Global open; Vol 11(6), pp. e5018. 2023 Jun 13.
1. Soldati S
2. Bär A
3. Vladymyrov M
4. Glavin D
5. McGrath JL
6. Gosselet F
7. Nishihara H
8. Goelz S
9. Engelhardt B
High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro.; Journal of neuroinflammation; Vol 20(1), pp. 123. 2023 May 23.
1. Ahmad SD
2. Cetin M
3. Waugh RE
4. McGrath JL
A computer vision approach for analyzing label free leukocyte trafficking dynamics on a microvascular mimetic.; Frontiers in immunology; Vol 14, pp. 1140395. 2023 Mar 24.
1. Hudecz D
2. McCloskey MC
3. Vergo S
4. Christensen S
5. McGrath JL
6. Nielsen MS
Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device.; International journal of molecular sciences; Vol 24(6). 2023 Mar 15.
1. Brunozzi D
2. LoPresti MA
3. McGrath JL
4. Alden TD
Approaches to ventriculoperitoneal shunt scalp erosion: countersinking into the calvarium. Illustrative case.; Journal of neurosurgery. Case lessons; Vol 6(22). 2023 Jan 27.
1. Li H
2. Le L
3. Marrero M
4. David-Bercholz J
5. Caceres AI
6. Lim C
7. Chiang W
8. Majewska AK
9. Terrando N
10. Gelbard HA
Neutrophilia with damage to the blood-brain barrier and neurovascular unit following acute lung injury.; bioRxiv : the preprint server for biology. 2023 Jan 17.
1. Cognetti JS
2. Moen MT
3. Brewer MG
4. Bryan MR
5. Tice JD
6. McGrath JL
7. Miller BL
A photonic biosensor-integrated tissue chip platform for real-time sensing of lung epithelial inflammatory markers.; Lab on a chip. 2023 Jan 03.
1. Mansouri M
2. Ahmed A
3. Ahmad SD
4. McCloskey MC
5. Joshi IM
6. Gaborski TR
7. Waugh RE
8. McGrath JL
9. Day SW
10. Abhyankar VV
The Modular μSiM Reconfigured: Integration of Microfluidic Capabilities to Study in vitro Barrier Tissue Models under Flow.; Advanced healthcare materials. 2022 Aug 11.
1. McCloskey MC
2. Kasap P
3. Ahmad SD
4. Su SH
5. Chen K
6. Mansouri M
7. Ramesh N
8. Nishihara H
9. Belyaev Y
10. Abhyankar VV
11. Begolo S
12. Singer BH
13. Webb KF
14. Kurabayashi K
15. Flax J
16. Waugh RE
17. Engelhardt B
18. McGrath JL
The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro.; Advanced healthcare materials. 2022 Jul 28.
1. Salminen AT
2. McCloskey MC
3. Ahmad SD
4. Romanick SS
5. Chen K
6. Houlihan W
7. Klaczko ME
8. Flax J
9. Waugh RE
10. McGrath JL
Molecular mechanisms underlying the heterogeneous barrier responses of two primary endothelial cell types to sphingosine-1-phosphate.; European journal of cell biology; Vol 101(3). 2022 May 11.
1. Su SH
2. Song Y
3. Stephens A
4. Situ M
5. McCloskey MC
6. McGrath JL
7. Andjelkovic AV
8. Singer BH
9. Kurabayashi K
A tissue chip with integrated digital immunosensors: In situ brain endothelial barrier cytokine secretion monitoring.; Biosensors & bioelectronics; Vol 224, pp. 115030. 2022 Jan 24.
1. McCloskey MC
2. Zhang VZ
3. Ahmad SD
4. Walker S
5. Romanick SS
6. Awad HA
7. McGrath JL
Sourcing cells for in vitro models of human vascular barriers of inflammation.; Frontiers in medical technology; Vol 4, pp. 979768. 2022 Jan 21.
1. Ledwon JK
2. Vaca EE
3. Huang CC
4. Kelsey LJ
5. McGrath JL
6. Topczewski J
7. Gosain AK
8. Topczewska JM
Langerhans cells and SFRP2/Wnt/beta-catenin signalling control adaptation of skin epidermis to mechanical stretching.; Journal of cellular and molecular medicine. 2022 Jan 12.
1. Riazanski V
2. Mauleon G
3. Lucas K
4. Walker S
5. Zimnicka AM
6. McGrath JL
7. Nelson DJ
Real time imaging of single extracellular vesicle pH regulation in a microfluidic cross-flow filtration platform.; Communications biology; Vol 5(1). 2022 Jan 10.
1. Ajalik RE
2. Alenchery RG
3. Cognetti JS
4. Zhang VZ
5. McGrath JL
6. Miller BL
7. Awad HA
Human Organ-on-a-Chip Microphysiological Systems to Model Musculoskeletal Pathologies and Accelerate Therapeutic Discovery.; Frontiers in bioengineering and biotechnology; Vol 10. 2022.
1. Klaczko ME
2. Lucas K
3. Salminen AT
4. McCloskey MC
5. Ozgurun B
6. Ward BM
7. Flax J
8. McGrath JL
Rapid and specific detection of intact viral particles using functionalized microslit silicon membranes as a fouling-based sensor.; The Analyst. 2021 Dec 21.
1. Nino G
2. Aziz J
3. Weiss M
4. Allen M
5. Lew J
6. Manrique M
7. Mantilla-Rivas E
8. McGrath JL
9. Rogers GF
10. Oh AK
Defining Age-related OSA Features in Robin Sequence Using Polysomnographic-based Analyses of Respiratory Arousal Responses and Gas-exchange Parameters.; The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 2021 Nov 17.
1. Yan Y
2. McGrath JL
3. Janes LE
4. Gosain AK
Establishment of Objective Clinical Parameters for Assessment of Trigonocephaly: Are Caliper-Derived Clinical Measures Adequate?; The Journal of craniofacial surgery. 2021 Jul 30.
1. Manrique M
2. McGrath JL
3. Bryant JR
4. Mantilla-Rivas E
5. Rana MS
6. Boyajian MK
7. Rogers GF
8. Oh AK
Device Malfunction Associated With Mandibular Distraction for Infants With Robin Sequence.; The Journal of craniofacial surgery. 2021 Jun 02.
1. Castro Dias M
2. Odriozola Quesada A
3. Soldati S
4. Bösch F
5. Gruber I
6. Hildbrand T
7. Sönmez D
8. Khire T
9. Witz G
10. McGrath JL
11. Piontek J
12. Kondoh M
13. Deutsch U
14. Zuber B
15. Engelhardt B
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood-brain barrier.; Journal of cell science; Vol 134(8). 2021 Apr 15.
1. Talbet JH
2. McGrath JL
3. Manrique M
4. Mantilla-Rivas E
5. Meany HJ
6. Oh AK
7. Rogers GF
Epithelioid Sarcoma in a Young Child: A Case Report and Literature Review.; Plastic and reconstructive surgery. Global open; Vol 9(2). 2021 Feb.
1. Masters EA
2. Muthukrishnan G
3. Ho L
4. Gill AL
5. de Mesy Bentley KL
6. Galloway CA
7. McGrath JL
8. Awad HA
9. Gill SR
10. Schwarz EM
Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis.; Frontiers in microbiology; Vol 12. 2021.
1. Salminen AT
2. Tithof J
3. Izhiman Y
4. Masters EA
5. McCloskey MC
6. Gaborski TR
7. Kelley DH
8. Pietropaoli AP
9. Waugh RE
10. McGrath JL
Endothelial cell apicobasal polarity coordinates distinct responses to luminally versus abluminally delivered TNF-α in a microvascular mimetic.; Integrative biology : quantitative biosciences from nano to macro. 2020 Nov 09.
1. Masters EA
2. de Mesy Bentley KL
3. Gill AL
4. Hao SP
5. Galloway CA
6. Salminen AT
7. Guy DR
8. McGrath JL
9. Awad HA
10. Gill SR
11. Schwarz EM
Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice.; PLoS pathogens; Vol 16(10). 2020 Oct 22.
1. Fazzino JZ
2. Mantilla-Rivas E
3. Talbet JH
4. Kapoor E
5. Manrique M
6. McGrath JL
7. Magge SN
8. Oh AK
9. Rogers GF
Abnormal Cranial Shape Preceding Radiographic Evidence of Craniosynostosis.; Plastic and reconstructive surgery. Global open; Vol 8(9). 2020 Sep.
1. Miller JJ
2. Carter JA
3. Hill K
4. DesOrmeaux JS
5. Carter RN
6. Gaborski TR
7. Roussie JA
8. McGrath JL
9. Johnson DG
Free Standing, Large-Area Silicon Nitride Membranes for High Toxin Clearance in Blood Surrogate for Small-Format Hemodialysis.; Membranes; Vol 10(6). 2020 Jun 06.
1. Khire TS
2. Salminen AT
3. Swamy H
4. Lucas KS
5. McCloskey MC
6. Ajalik RE
7. Chung HH
8. Gaborski TR
9. Waugh RE
10. Glading AJ
11. McGrath JL
Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions.; Cellular and molecular bioengineering; Vol 13(2). 2020 Apr.
1. Hill K
2. Walker SN
3. Salminen A
4. Chung HL
5. Li X
6. Ezzat B
7. Miller JJ
8. DesOrmeaux JS
9. Zhang J
10. Hayden A
11. Burgin T
12. Piraino L
13. May MN
14. Gaborski TR
15. Roussie JA
16. Taylor J
17. DiVincenti L
18. Shestopalov AA
19. McGrath JL
20. Johnson DG
Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis.; Advanced healthcare materials; Vol 9(4). 2020 Feb.