URMC / Labs / Mooney Lab / Publications Publications Farnsworth CWSchott EMBenvie AMZukoski JKates SLSchwarz EMGill SRZuscik MJMooney RA (2017 Dec 11). Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation and osteolysis during Staphylococcus aureus implant-associated bone infection. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Farnsworth CWSchott EMJensen SEZukoski JBenvie AMRefaai MAKates SLSchwarz EMZuscik MJGill SRMooney RA (2017 Mar 20). Adaptive upregulation of Clumping Factor A (ClfA) by S. aureus in the obese, type 2 diabetic host mediates increased virulence. Infection and immunity. Dar QASchott EMCatheline SEMaynard RDLiu ZKamal FFarnsworth CWKetz JPMooney RAHilton MJJonason JHPrawitt JZuscik MJ (2017). Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. PloS one. Wexler OGough MSMorgan MAMack CMApostolakos MJDoolin KPMooney RAArning EBottiglieri TPietropaoli AP (2016 Sep 2). Methionine Metabolites in Patients With Sepsis. Journal of intensive care medicine. Hamada DMaynard RSchott EDrinkwater CJKetz JPKates SLJonason JHHilton MJZuscik MJMooney RA (2016 Jun). Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus. Arthritis & rheumatology (Hoboken, N.J.). Beier EEInzana JASheu TJShu LPuzas JEMooney RA (2015 Oct). Effects of Combined Exposure to Lead and High-Fat Diet on Bone Quality in Juvenile Male Mice. Environmental health perspectives. Farnsworth CWShehatou CTMaynard RNishitani KKates SLZuscik MJSchwarz EMDaiss JLMooney RA (2015 Jun). A humoral immune defect distinguishes the response to Staphylococcus aureus infections in mice with obesity and type 2 diabetes from that in mice with type 1 diabetes. Infection and immunity. Barry CTHazard CHah ZCheng GPartin AMooney RAChuang KHCao WRubens DJParker KJ (2015 Jun). Shear wave dispersion in lean versus steatotic rat livers. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. Shu LBeier ESheu TZhang HZuscik MJPuzas EJBoyce BFMooney RAXing L (2015 Apr). High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment. Calcified tissue international. Barry CTHah ZPartin AMooney RAChuang KHAugustine AAlmudevar ACao WRubens DJParker KJ (2014 Apr). Mouse liver dispersion for the diagnosis of early-stage Fatty liver disease: a 70-sample study. Ultrasound in medicine & biology. David MAJones KHInzana JAZuscik MJAwad HAMooney RA (2014). Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes. PloS one. Brown MLYukata KFarnsworth CWChen DGAwad HHilton MJO'Keefe RJXing LMooney RAZuscik MJ (2014). Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus. PloS one. Inzana JAKung MShu LHamada DXing LPZuscik MJAwad HAMooney RA (2013 Nov). Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur. Bone. Shi JXLiang QQWang YJMooney RABoyce BFXing L (2013 Nov). Use of a whole-slide imaging system to assess the presence and alteration of lymphatic vessels in joint sections of arthritic mice. Biotechnic & histochemistry : official publication of the Biological Stain Commission. Mirando AJLiu ZMoore TLang AKohn AOsinski AMO'Keefe RJMooney RAZuscik MJHilton MJ (2013 Oct). RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis and rheumatism. Curtin WMMenegus MAPatru MMPeterson CJMetlay LAMooney RAStanwood NLScheible ALDorgan A (2013). Midtrimester fetal herpes simplex-2 diagnosis by serology, culture and quantitative polymerase chain reaction. Fetal diagnosis and therapy. Barry CTMills BHah ZMooney RARyan CKRubens DJParker KJ (2012 Feb). Shear wave dispersion measures liver steatosis. Ultrasound in medicine & biology. Clementi AHGaudy AMZimmers TAKoniaris LGMooney RA (2011 Nov). Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse. Metabolism: clinical and experimental. Sampson ERHilton MJTian YChen DSchwarz EMMooney RABukata SVO'Keefe RJAwad HPuzas JERosier RNZuscik MJ (2011 Sep 21). Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. Science translational medicine. Gough MSMorgan MAMack CMDarling DCFrasier LMDoolin KPApostolakos MJStewart JCGraves BTArning EBottiglieri TMooney RAFrampton MWPietropaoli AP (2011 Jun). The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis. Critical care medicine. Mooney RASampson ERLerea JRosier RNZuscik MJ (2011). High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury. Arthritis research & therapy. Gaudy AMClementi AHCampbell JSSmrcka AVMooney RA (2010 Dec 31). Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes. The Journal of biological chemistry. Galloway CAAshton JSparks JDMooney RASmith HC (2010 Nov). Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes. Biochimica et biophysica acta. Clementi AHGaudy AMvan Rooijen NPierce RHMooney RA (2009 Nov). Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling. Biochimica et biophysica acta. Thornburg LLKnight KMPeterson CJMcCall KBMooney RAPressman EK (2008 Aug). Maternal serum alpha-fetoprotein values in type 1 and type 2 diabetic patients. American journal of obstetrics and gynecology. Navaneethan SDMooney RASloand J (2008 Jan 01). Pseudo-anion gap acidosis NDT Plus. Mooney RA (2007 Feb). Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis. Journal of applied physiology (Bethesda, Md. : 1985). Chagnon MJElchebly MUetani NDombrowski LCheng AMooney RAMarette ATremblay ML (2006 Jul). Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma. Canadian journal of physiology and pharmacology. Klover PJClementi AHMooney RA (2005 Aug). Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology. LeVea CMReeder JEMooney RA (2004 Jul 1). EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation. Experimental cell research. Klover PJMooney RA (2004 May). Hepatocytes: critical for glucose homeostasis. The international journal of biochemistry & cell biology. Baliff JPMooney RA (2003 Dec). New developments in prenatal screening for Down syndrome. American journal of clinical pathology. Klover PJZimmers TAKoniaris LGMooney RA (2003 Nov). Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes. Arnold GLHyman SLMooney RAKirby RS (2003 Aug). Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies. Journal of autism and developmental disorders. Polliotti BMFry AGSaller DNMooney RACox CMiller RK (2003 Jun). Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia. Obstetrics and gynecology. Pearce DAMcCall KMooney RAChattopadhyay SCurran TM (2003 Jun). Altered amino acid levels in sera of a mouse model for juvenile neuronal ceroid lipofuscinoses. Clinica chimica acta; international journal of clinical chemistry. Senn JJKlover PJNowak IAZimmers TAKoniaris LGFurlanetto RWMooney RA (2003 Apr 18). Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. The Journal of biological chemistry. Mooney RALeVea CM (2003). The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting. Current topics in medicinal chemistry. Senn JJKlover PJNowak IAMooney RA (2002 Dec). Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes. Symons JRLeVea CMMooney RA (2002 Jul 15). Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes. The Biochemical journal. Mooney RASenn JCameron SInamdar NBoivin LMShang YFurlanetto RW (2001 Jul 13). Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance. The Journal of biological chemistry. Levea CMMcgary CTSymons JRMooney RA (2000 Nov). PTP LAR expression compared to prognostic indices in metastatic and non-metastatic breast cancer. Breast cancer research and treatment. Bleyle LAPeng YEllis CMooney RA (1999 Oct). Dissociation of PTPase levels from their modulation of insulin receptor signal transduction. Cellular signalling. Hostetler MAArnold GLMooney RBennett MJRinaldo PRoe CR (1999 Sep). Hypoketotic hypoglycemic coma in a 21-month-old child. Annals of emergency medicine. Saller DNCanick JAKellner LHRose NCGarza JFrench CAMooney RA (1997 Oct). Maternal serum analyte levels in pregnancies with fetal Down syndrome resulting from translocations. American journal of obstetrics and gynecology. Phung TLMooney RAKulas DTSparks CESparks JD (1997 Aug 18). Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells. Biochemical and biophysical research communications. Mooney RAKulas DTBleyle LANovak JS (1997 Jun 27). The protein tyrosine phosphatase LAR has a major impact on insulin receptor dephosphorylation. Biochemical and biophysical research communications. Kulas DTGoldstein BJMooney RA (1996 Jan 12). The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases. The Journal of biological chemistry. Kulas DTFreund GGMooney RA (1996 Jan 12). The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling. The Journal of biological chemistry. Mooney RAArvan DASaller DNFrench CAPeterson CJ (1995 Dec). Decreased maternal serum hCG levels with increasing gravidity and parity. Obstetrics and gynecology.