Recent Publications

• 1. Wu J
  2. Subbaiah KCV
  3. Hedaya O
  4. Chen S
  5. Munger J
  6. Tang WHW
  7. Yan C
  8. Yao P
  FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis.; Cardiovascular research. 2023 Jul 31.
• 1. Dunn DM
  2. Pack LJ
  3. Munger JC
  Raf1 promotes successful Human Cytomegalovirus replication and is regulated by AMPK-mediated phosphorylation during infection.; bioRxiv : the preprint server for biology. 2023 Jul 26.
• 1. Zhang K
  2. Eldin P
  3. Ciesla JH
  4. Briant L
  5. Lentini JM
  6. Ramos J
  7. Cobb J
  8. Munger J
  9. Fu D
  Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease.; bioRxiv : the preprint server for biology. 2023 Jul 20.
• 1. Raymonda MH
  2. Rodríguez-Sánchez I
  3. Schafer XL
  4. Smorodintsev-Schiller L
  5. Harris IS
  6. Munger J
  Cytomegalovirus-induced inactivation of TSC2 disrupts the coupling of fatty acid biosynthesis to glucose availability resulting in a vulnerability to glucose limitation.; bioRxiv : the preprint server for biology. 2023 May 17.
• 1. Asantewaa G
  2. Tuttle ET
  3. Ward NP
  4. Kang YP
  5. Kim Y
  6. Kavanagh ME
  7. Girnius N
  8. Chen Y
  9. Duncan R
  10. Rodriguez K
  11. Hecht F
  12. Zocchi M
  13. Smorodintsev-Schiller L
  14. Scales TQ
  15. Taylor K
  16. Alimohammadi F
  17. Sechrist ZR
  18. Agostini-Vulaj D
  19. Schafer XL
  20. Chang H
  21. Smith Z
  22. O'Connor TN
  23. Whelan S
  24. Selfors LM
  25. Crowdis J
  26. Gray GK
  27. Bronson RT
  28. Brenner D
  29. Rufini A
  30. Dirksen RT
  31. Hezel AF
  32. Huber AR
  33. Munger J
  34. Cravatt BF
  35. Vasiliou V
  36. Cole CL
  37. DeNicola GM
  38. Harris IS
  Glutathione supports lipid abundance in vivo.; bioRxiv : the preprint server for biology. 2023 Feb 11.
• 1. Goodrum F
  2. Lowen A
  3. Lakdawala S
  4. Alwine J
  5. Casadevall A
  6. Imperiale M
  7. Atwood W
  8. Avgousti D
  9. Baines J
  10. Banfield B
  11. Banks L
  12. Bhaduri-McIntosh S
  13. Bhattacharya D
  14. Blanco-Melo D
  15. Bloom D
  16. Boon A
  17. Boulant S
  18. Brandt C
  19. Broadbent A
  20. Brooke C
  21. Cameron C
  22. Campos S
  23. Caposio P
  24. Chan G
  25. Cliffe A
  26. Coffin J
  27. Collins K
  28. Damania B
  29. Daugherty M
  30. Debbink K
  31. DeCaprio J
  32. Dermody T
  33. Dikeakos J
  34. DiMaio D
  35. Dinglasan R
  36. Duprex WP
  37. Dutch R
  38. Elde N
  39. Emerman M
  40. Enquist L
  41. Fane B
  42. Fernandez-Sesma A
  43. Flenniken M
  44. Frappier L
  45. Frieman M
  46. Frueh K
  47. Gack M
  48. Gaglia M
  49. Gallagher T
  50. Galloway D
  51. García-Sastre A
  52. Geballe A
  53. Glaunsinger B
  54. Goff S
  55. Greninger A
  56. Hancock M
  57. Harris E
  58. Heaton N
  59. Heise M
  60. Heldwein E
  61. Hogue B
  62. Horner S
  63. Hutchinson E
  64. Hyser J
  65. Jackson W
  66. Kalejta R
  67. Kamil J
  68. Karst S
  69. Kirchhoff F
  70. Knipe D
  71. Kowalik T
  72. Lagunoff M
  73. Laimins L
  74. Langlois R
  75. Lauring A
  76. Lee B
  77. Leib D
  78. Liu SL
  79. Longnecker R
  80. Lopez C
  81. Luftig M
  82. Lund J
  83. Manicassamy B
  84. McFadden G
  85. McIntosh M
  86. Mehle A
  87. Miller WA
  88. Mohr I
  89. Moody C
  90. Moorman N
  91. Moscona A
  92. Mounce B
  93. Munger J
  94. Münger K
  95. Murphy E
  96. Naghavi M
  97. Nelson J
  98. Neufeldt C
  99. Nikolich J
  100. O'Connor C
  101. Ono A
  102. Orenstein W
  103. Ornelles D
  104. Ou JH
  105. Parker J
  106. Parrish C
  107. Pekosz A
  108. Pellett P
  109. Pfeiffer J
  110. Plemper R
  111. Polyak S
  112. Purdy J
  113. Pyeon D
  114. Quinones-Mateu M
  115. Renne R
  116. Rice C
  117. Schoggins J
  118. Roller R
  119. Russell C
  120. Sandri-Goldin R
  121. Sapp M
  122. Schang L
  123. Schmid S
  124. Schultz-Cherry S
  125. Semler B
  126. Shenk T
  127. Silvestri G
  128. Simon V
  129. Smith G
  130. Smith J
  131. Spindler K
  132. Stanifer M
  133. Subbarao K
  134. Sundquist W
  135. Suthar M
  136. Sutton T
  137. Tai A
  138. Tarakanova V
  139. tenOever B
  140. Tibbetts S
  141. Tompkins S
  142. Toth Z
  143. van Doorslaer K
  144. Vignuzzi M
  145. Wallace N
  146. Walsh D
  147. Weekes M
  148. Weinberg J
  149. Weitzman M
  150. Weller S
  151. Whelan S
  152. White E
  153. Williams B
  154. Wobus C
  155. Wong S
  156. Yurochko A
  Virology under the Microscope-a Call for Rational Discourse.; mBio. 2023 Jan 26.
• 1. Ciesla J
  2. Moreno I
  3. Munger J
  TNFα-induced metabolic reprogramming drives an intrinsic anti-viral state.; PLoS pathogens; Vol 18(7), pp. e1010722. 2022 Jul 14.
• 1. Moreno I
  2. Rodríguez-Sánchez I
  3. Schafer X
  4. Munger J
  Human cytomegalovirus induces neuronal enolase to support virally mediated metabolic remodeling.; Proceedings of the National Academy of Sciences of the United States of America; Vol 119(49), pp. e2205789119. 2022 Jan 02.
• 1. Raymonda MH
  2. Ciesla JH
  3. Monaghan M
  4. Leach J
  5. Asantewaa G
  6. Smorodintsev-Schiller LA
  7. Lutz MM
  8. Schafer XL
  9. Takimoto T
  10. Dewhurst S
  11. Munger J
  12. Harris IS
  Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro.; Virology; Vol 566. 2021 Nov 27.
• 1. Monaghan M
  2. Munger J
  Contributions of the HCMV UL30-associated open reading frames to infection.; Journal of virology. 2021 Feb 10.
• 1. Dunn DM
  2. Rodriguez-Sanchez I
  3. Schafer X
  4. Munger J
  Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection.; Journal of virology. 2020 Dec 02.
• 1. Dunn DM
  2. Munger J
  Interplay Between Calcium and AMPK Signaling in Human Cytomegalovirus Infection.; Frontiers in cellular and infection microbiology; Vol 10. 2020.
• 1. Goodwin CM
  2. Schafer X
  3. Munger J
  UL26 attenuates IKKβ-mediated induction of ISG expression and enhanced protein ISGylation during HCMV infection.; Journal of virology. 2019 Sep 18.
• 1. Meade N
  2. King M
  3. Munger J
  4. Walsh D
  mTOR Dysregulation by Vaccinia Virus F17 Controls Multiple Processes with Varying Roles in Infection.; Journal of virology; Vol 93(15). 2019 Aug 01.
• 1. Rodríguez-Sánchez I
  2. Munger J
  Meal for Two: Human Cytomegalovirus-Induced Activation of Cellular Metabolism.; Viruses; Vol 11(3). 2019 Mar 19.
• 1. Goodwin CM
  2. Munger J
  The IκB kinases restrict human cytomegalovirus infection.; Journal of virology. 2019 Feb 13.
• 1. King MW
  2. Munger J
  Editing the human cytomegalovirus genome with the CRISPR/Cas9 system.; Virology; Vol 529. 2019 Jan 26.
• 1. Rodríguez-Sánchez I
  2. Schafer XL
  3. Monaghan M
  4. Munger J
  The Human Cytomegalovirus UL38 protein drives mTOR-independent metabolic flux reprogramming by inhibiting TSC2.; PLoS pathogens; Vol 15(1). 2019 Jan 24.
• 1. Goodwin CM
  2. Ciesla JH
  3. Munger J
  Who's Driving? Human Cytomegalovirus, Interferon, and NFκB Signaling.; Viruses; Vol 10(9). 2018 Aug 21.
• 1. Nadtochiy SM
  2. Wang YT
  3. Nehrke K
  4. Munger J
  5. Brookes PS
  Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.; Journal of molecular and cellular cardiology. 2018 Jun 26.
• 1. Zhang J
  2. Wang YT
  3. Miller JH
  4. Day MM
  5. Munger JC
  6. Brookes PS
  Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity.; Cell reports; Vol 23(9). 2018 May 29.
• 1. Nadtochiy SM
  2. Wang YT
  3. Zhang J
  4. Nehrke K
  5. Schafer X
  6. Welle K
  7. Ghaemmaghami S
  8. Munger J
  9. Brookes PS
  Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.; The Biochemical journal. 2017 Jul 03.
• 1. Murphy PS
  2. Wang J
  3. Bhagwat SP
  4. Munger JC
  5. Janssen WJ
  6. Wright TW
  7. Elliott MR
  CD73 regulates anti-inflammatory signaling between apoptotic cells and endotoxin-conditioned tissue macrophages.; Cell death and differentiation; Vol 24(3). 2017 Mar.
• 1. Smith B
  2. Schafer XL
  3. Ambeskovic A
  4. Spencer CM
  5. Land H
  6. Munger J
  Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells.; Cell reports; Vol 17(3). 2016 Oct 11.
• 1. Nadtochiy SM
  2. Schafer X
  3. Fu D
  4. Nehrke K
  5. Munger J
  6. Brookes PS
  Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling.; The Journal of biological chemistry; Vol 291(38). 2016 Sep 16.
• 1. Xu S
  2. Schafer X
  3. Munger J
  Expression of Oncogenic Alleles Induces Multiple Blocks to Human Cytomegalovirus Infection.; Journal of virology; Vol 90(9). 2016 May 1.
• 1. Hollenbaugh JA
  2. Montero C
  3. Schinazi RF
  4. Munger J
  5. Kim B
  Metabolic profiling during HIV-1 and HIV-2 infection of primary human monocyte-derived macrophages.; Virology; Vol 491. 2016 Apr.
• 1. Goodwin CM
  2. Xu S
  3. Munger J
  Stealing the Keys to the Kitchen: Viral Manipulation of the Host Cell Metabolic Network.; Trends in microbiology; Vol 23(12). 2015 Dec.
• 1. Nadtochiy SM
  2. Urciuoli W
  3. Zhang J
  4. Schafer X
  5. Munger J
  6. Brookes PS
  Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation.; Journal of molecular and cellular cardiology; Vol 88. 2015 Nov.
• 1. Campbell A
  2. Bushman J
  3. Munger J
  4. Noble M
  5. Pröschel C
  6. Mayer-Pröschel M
  Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.; Glia. 2015 Oct 15.
• 1. Buescher JM
  2. Antoniewicz MR
  3. Boros LG
  4. Burgess SC
  5. Brunengraber H
  6. Clish CB
  7. DeBerardinis RJ
  8. Feron O
  9. Frezza C
  10. Ghesquiere B
  11. Gottlieb E
  12. Hiller K
  13. Jones RG
  14. Kamphorst JJ
  15. Kibbey RG
  16. Kimmelman AC
  17. Locasale JW
  18. Lunt SY
  19. Maddocks OD
  20. Malloy C
  21. Metallo CM
  22. Meuillet EJ
  23. Munger J
  24. Nöh K
  25. Rabinowitz JD
  26. Ralser M
  27. Sauer U
  28. Stephanopoulos G
  29. St-Pierre J
  30. Tennant DA
  31. Wittmann C
  32. Vander Heiden MG
  33. Vazquez A
  34. Vousden K
  35. Young JD
  36. Zamboni N
  37. Fendt SM
  A roadmap for interpreting (13)C metabolite labeling patterns from cells.; Current opinion in biotechnology; Vol 34. 2015 Aug.
• 1. Xu S
  2. Spencer CM
  3. Munger J
  Transformation with oncogenic Ras and the simian virus 40 T antigens induces caspase-dependent sensitivity to fatty acid biosynthetic inhibition.; Journal of virology; Vol 89(12). 2015 Jun.
• 1. DeVito SR
  2. Ortiz-Riaño E
  3. Martínez-Sobrido L
  4. Munger J
  Cytomegalovirus-mediated activation of pyrimidine biosynthesis drives UDP-sugar synthesis to support viral protein glycosylation.; Proceedings of the National Academy of Sciences of the United States of America; Vol 111(50). 2014 Dec 16.
• 1. Mathers C
  2. Schafer X
  3. Martínez-Sobrido L
  4. Munger J
  The human cytomegalovirus UL26 protein antagonizes NF-κB activation.; Journal of virology; Vol 88(24). 2014 Dec.
• 1. Proschel C
  2. Stripay JL
  3. Shih CH
  4. Munger JC
  5. Noble MD
  Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons.; EMBO molecular medicine; Vol 6(4). 2014 Apr.
• 1. Ortiz-Riaño E
  2. Ngo N
  3. Devito S
  4. Eggink D
  5. Munger J
  6. Shaw ML
  7. de la Torre JC
  8. Martínez-Sobrido L
  Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.; Journal of virology; Vol 88(2). 2014 Jan.
• 1. Mathers C
  2. Spencer CM
  3. Munger J
  Distinct domains within the human cytomegalovirus U(L)26 protein are important for wildtype viral replication and virion stability.; PloS one; Vol 9(2). 2014.
• 1. Pei S
  2. Minhajuddin M
  3. Callahan KP
  4. Balys M
  5. Ashton JM
  6. Neering SJ
  7. Lagadinou ED
  8. Corbett C
  9. Ye H
  10. Liesveld JL
  11. O'Dwyer KM
  12. Li Z
  13. Shi L
  14. Greninger P
  15. Settleman J
  16. Benes C
  17. Hagen FK
  18. Munger J
  19. Crooks PA
  20. Becker MW
  21. Jordan CT
  Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.; The Journal of biological chemistry; Vol 288(47). 2013 Nov 22.
• 1. Sasaki M
  2. Knobbe CB
  3. Munger JC
  4. Lind EF
  5. Brenner D
  6. Brüstle A
  7. Harris IS
  8. Holmes R
  9. Wakeham A
  10. Haight J
  11. You-Ten A
  12. Li WY
  13. Schalm S
  14. Su SM
  15. Virtanen C
  16. Reifenberger G
  17. Ohashi PS
  18. Barber DL
  19. Figueroa ME
  20. Melnick A
  21. Zúñiga-Pflücker JC
  22. Mak TW
  IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.; Nature; Vol 488(7413). 2012 Aug 30.
• 1. McArdle J
  2. Moorman NJ
  3. Munger J
  HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.; PLoS pathogens; Vol 8(1). 2012 Jan.
• 1. Wang R
  2. Dillon CP
  3. Shi LZ
  4. Milasta S
  5. Carter R
  6. Finkelstein D
  7. McCormick LL
  8. Fitzgerald P
  9. Chi H
  10. Munger J
  11. Green DR
  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.; Immunity; Vol 35(6). 2011 Dec 23.
• 1. Hollenbaugh JA
  2. Munger J
  3. Kim B
  Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC-MS/MS analysis.; Virology; Vol 415(2). 2011 Jul 5.
• 1. Spencer CM
  2. Schafer XL
  3. Moorman NJ
  4. Munger J
  Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.; Journal of virology; Vol 85(12). 2011 Jun.
• 1. McArdle J
  2. Schafer XL
  3. Munger J
  Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny.; Journal of virology; Vol 85(2). 2011 Jan.
• 1. Munger J
  2. Bennett BD
  3. Parikh A
  4. Feng XJ
  5. McArdle J
  6. Rabitz HA
  7. Shenk T
  8. Rabinowitz JD
  Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy.; Nature biotechnology; Vol 26(10). 2008 Oct.
• 1. Munger J
  2. Bajad SU
  3. Coller HA
  4. Shenk T
  5. Rabinowitz JD
  Dynamics of the cellular metabolome during human cytomegalovirus infection.; PLoS pathogens; Vol 2(12). 2006 Dec.
• 1. Munger J
  2. Yu D
  3. Shenk T
  UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells.; Journal of virology; Vol 80(7). 2006 Apr.
• 1. Benetti L
  2. Munger J
  3. Roizman B
  The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD.; Journal of virology; Vol 77(11). 2003 Jun.
• 1. Munger J
  2. Hagglund R
  3. Roizman B
  Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis.; Virology; Vol 305(2). 2003 Jan 20.
• 1. Munger J
  2. Zhou G
  3. Roizman B
  Cell death on demand: Herpes simplex viruses and apoptosis; In C. D. O?Connor (ed.), Microbial Subversion of Host Cells, Cambridge University Press, Cambridge. 2003 Jan 01.