Recent Publications

• 1. Sun W
  2. Cornwell A
  3. Li J
  4. Peng S
  5. Osorio MJ
  6. Su Wanga NA
  7. Benraiss A
  8. Lou N
  9. Goldman SA
  10. Nedergaard M
  (2017 Mar 23). SOX9 is an astrocyte-specific nuclear marker in the adult brain outside the neurogenic regions. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Ratner V
  2. Gao Y
  3. Lee H
  4. Elkin R
  5. Nedergaard M
  6. Benveniste H
  7. Tannenbaum A
  (2017 Mar 18). Cerebrospinal and interstitial fluid transport via the glymphatic pathway modeled by optimal mass transport. NeuroImage.
• 1. de Leon MJ
  2. Li Y
  3. Okamura N
  4. Tsui WH
  5. Saint Louis LA
  6. Glodzik L
  7. Osorio RS
  8. Fortea J
  9. Butler T
  10. Pirraglia E
  11. Fossati S
  12. Kim HJ
  13. Carare RO
  14. Nedergaard M
  15. Benveniste H
  16. Rusinek H
  (2017 Mar 16). CSF clearance in Alzheimer Disease measured with dynamic PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
• 1. Wang M
  2. Ding F
  3. Deng S
  4. Guo X
  5. Wang W
  6. Iliff JJ
  7. Nedergaard M
  (2017 Mar 15). Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Cotrina ML
  2. Lou N
  3. Tome-Garcia J
  4. Goldman J
  5. Nedergaard M
  (2017 Feb 20). Direct comparison of microglial dynamics and inflammatory profile in photothrombotic and arterial occlusion evoked stroke. Neuroscience.
• 1. Kjaerby C
  2. Rasmussen R
  3. Andersen M
  4. Nedergaard M
  (2017 Feb 16). Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function? Neurochemical research.
• 1. Achariyar TM
  2. Li B
  3. Peng W
  4. Verghese PB
  5. Shi Y
  6. McConnell E
  7. Benraiss A
  8. Kasper T
  9. Song W
  10. Takano T
  11. Holtzman DM
  12. Nedergaard M
  13. Deane R
  (2017 Jan 12). Erratum to: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. Molecular neurodegeneration.
• 1. Achariyar TM
  2. Li B
  3. Peng W
  4. Verghese PB
  5. Shi Y
  6. McConnell E
  7. Benraiss A
  8. Kasper T
  9. Song W
  10. Takana T
  11. Holtzman DM
  12. Nedergaard M
  13. Deane R
  (2016 Dec 08). Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. Molecular neurodegeneration.
• 1. Bosetti F
  2. Galis ZS
  3. Bynoe MS
  4. Charette M
  5. Cipolla MJ
  6. Del Zoppo GJ
  7. Gould D
  8. Hatsukami TS
  9. Jones TL
  10. Koenig JI
  11. Lutty GA
  12. Maric-Bilkan C
  13. Stevens T
  14. Tolunay HE
  15. Koroshetz W
  (2016 Nov 04). "Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health Workshop. Journal of the American Heart Association.
• 1. Wang F
  2. Wang X
  3. Shapiro LA
  4. Cotrina ML
  5. Liu W
  6. Wang EW
  7. Gu S
  8. Wang W
  9. He X
  10. Nedergaard M
  11. Huang JH
  (2016 Sep 1). NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility. Brain structure & function.
• 1. Verkhratsky A
  2. Nedergaard M
  (2016 Aug 5). The homeostatic astroglia emerges from evolutionary specialization of neural cells. Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
• 1. Lundgaard I
  2. Lu ML
  3. Yang E
  4. Peng W
  5. Mestre H
  6. Hitomi E
  7. Deane R
  8. Nedergaard M
  (2016 Aug 1). Glymphatic clearance controls state-dependent changes in brain lactate concentration. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
• 1. Jiang Q
  2. Zhang L
  3. Ding G
  4. Davoodi-Bojd E
  5. Li Q
  6. Li L
  7. Sadry N
  8. Nedergaard M
  9. Chopp M
  10. Zhang Z
  (2016 Jun 15). Impairment of the glymphatic system after diabetes. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
• 1. Benraiss A
  2. Wang S
  3. Herrlinger S
  4. Li X
  5. Chandler-Militello D
  6. Mauceri J
  7. Burm HB
  8. Toner M
  9. Osipovitch M
  10. Jim Xu Q
  11. Ding F
  12. Wang F
  13. Kang N
  14. Kang J
  15. Curtin PC
  16. Brunner D
  17. Windrem MS
  18. Munoz-Sanjuan I
  19. Nedergaard M
  20. Goldman SA
  (2016 Jun 07). Human glia can both induce and rescue aspects of disease phenotype in Huntington disease. Nature communications.
• 1. Peng W
  2. Achariyar TM
  3. Li B
  4. Liao Y
  5. Mestre H
  6. Hitomi E
  7. Regan S
  8. Kasper T
  9. Peng S
  10. Ding F
  11. Benveniste H
  12. Nedergaard M
  13. Deane R
  (2016 May 24). Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease. Neurobiology of disease.
• 1. Ding F
  2. O'Donnell J
  3. Xu Q
  4. Kang N
  5. Goldman N
  6. Nedergaard M
  (2016 Apr 29). Changes in the composition of brain interstitial ions control the sleep-wake cycle. Science (New York, N.Y.).
• 1. Nedergaard M
  2. Goldman SA
  (2016 Mar). BRAIN DRAIN. Scientific American.
• 1. Lou N
  2. Takano T
  3. Pei Y
  4. Xavier AL
  5. Goldman SA
  6. Nedergaard M
  (2016 Jan 11). Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. Proceedings of the National Academy of Sciences of the United States of America.
• 1. Rasmussen R
  2. Nedergaard M
  3. Petersen NC
  (2016). Sulforhodamine 101, a widely used astrocyte marker, can induce cortical seizure-like activity at concentrations commonly used. Scientific reports.
• 1. Xie L
  2. Kang H
  3. Nedergaard M
  (2016). A Novel Model of Transient Occlusion of the Middle Cerebral Artery in Awake Mice. Journal of nature and science.
• 1. Kiviniemi V
  2. Wang X
  3. Korhonen V
  4. Keinänen T
  5. Tuovinen T
  6. Autio J
  7. LeVan P
  8. Keilholz S
  9. Zang YF
  10. Hennig J
  11. Nedergaard M
  (2015 Dec 21). Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms? Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
• 1. McConnell ED
  2. Wei HS
  3. Reitz KM
  4. Kang H
  5. Takano T
  6. Vates GE
  7. Nedergaard M
  (2015 Oct 14). Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
• 1. Sreetama SC
  2. Takano T
  3. Nedergaard M
  4. Simon SM
  5. Jaiswal JK
  (2015 Oct 9). Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis. Cell death and differentiation.
• 1. Iliff JJ
  2. Goldman SA
  3. Nedergaard M
  (2015 Oct). Implications of the discovery of brain lymphatic pathways. The Lancet. Neurology.
• 1. Ribeiro Xavier AL
  2. Kress BT
  3. Goldman SA
  4. Lacerda de Menezes JR
  5. Nedergaard M
  (2015 Aug 26). A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Lee H
  2. Xie L
  3. Yu M
  4. Kang H
  5. Feng T
  6. Deane R
  7. Logan J
  8. Nedergaard M
  9. Benveniste H
  (2015 Aug 5). The Effect of Body Posture on Brain Glymphatic Transport. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Benveniste H
  2. Hof PR
  3. Nedergaard M
  4. Bechter K
  (2015 Sep 1). Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals. The Journal of comparative neurology.
• 1. Wei HS
  2. Rasheed ID
  3. Takano T
  4. Kang H
  5. Reitz KM
  6. Gershteyn A
  7. Vates GE
  8. Nedergaard M
  (2015 Aug). 156 Capillary-Level Control of Cerebrovascular Tone. Neurosurgery.
• 1. Makaryus R
  2. Lee H
  3. Feng T
  4. Park JH
  5. Nedergaard M
  6. Jacob Z
  7. Enikolopov G
  8. Benveniste H
  (2015 Jul 16). Brain Maturation in Neonatal Rodents Is Impeded by Sevoflurane Anesthesia. Anesthesiology.
• 1. Liu X
  2. Wang C
  3. Fujita T
  4. Malmstrom HS
  5. Nedergaard M
  6. Ren YF
  7. Dirksen RT
  (2015 Jun 30). External Dentin Stimulation Induces ATP Release in Human Teeth. Journal of dental research.
• 1. Staberg M
  2. Michaelsen SR
  3. Olsen LS
  4. Nedergaard MK
  5. Villingshøj M
  6. Stockhausen MT
  7. Hamerlik P
  8. Poulsen HS
  (2016). Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro. Cancer cell international.
• 1. Goldman SA
  2. Nedergaard M
  3. Windrem MS
  (2015 May 24). Modeling cognition and disease using human glial chimeric mice. Glia.
• 1. Thrane AS
  2. Rangroo Thrane V
  3. Plog BA
  4. Nedergaard M
  (2015 May 22). Filtering the muddied waters of brain edema. Trends in neurosciences.
• 1. Jessen NA
  2. Munk AS
  3. Lundgaard I
  4. Nedergaard M
  (2015 May 7). The Glymphatic System: A Beginner's Guide. Neurochemical research.
• 1. Plog BA
  2. Nedergaard M
  (2015 Mar 30). Why have we not yet developed a simple blood test for TBI? Expert review of neurotherapeutics.
• 1. O'Donnell J
  2. Ding F
  3. Nedergaard M
  (2015 Mar). Distinct functional states of astrocytes during sleep and wakefulness: Is norepinephrine the master regulator? Current sleep medicine reports.
• 1. Ratner V
  2. Zhu L
  3. Kolesov I
  4. Nedergaard M
  5. Benveniste H
  6. Tannenbaum A
  (2015 Feb 21). Optimal-mass-transfer-based estimation of glymphatic transport in living brain. Proceedings of SPIE--the International Society for Optical Engineering.
• 1. Benveniste H
  2. Hof PR
  3. Nedergaard M
  4. Bechter K
  (2015 Feb 16). Modern Cerebrospinal Fluid Flow Research and Heinrich Quincke's Seminal 1872 Paper on the Distribution of Cinnabar in Freely Moving Animals. The Journal of comparative neurology.
• 1. Plog BA
  2. Dashnaw ML
  3. Hitomi E
  4. Peng W
  5. Liao Y
  6. Lou N
  7. Deane R
  8. Nedergaard M
  (2015 Jan 14). Biomarkers of Traumatic Injury Are Transported from Brain to Blood via the Glymphatic System. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Snyder HM
  2. Corriveau RA
  3. Craft S
  4. Faber JE
  5. Greenberg SM
  6. Knopman D
  7. Lamb BT
  8. Montine TJ
  9. Nedergaard M
  10. Schaffer CB
  11. Schneider JA
  12. Wellington C
  13. Wilcock DM
  14. Zipfel GJ
  15. Zlokovic B
  16. Bain LJ
  17. Bosetti F
  18. Galis ZS
  19. Koroshetz W
  20. Carrillo MC
  (2014 Dec 12). Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association.
• 1. Haydon PG
  2. Nedergaard M
  (2014 Dec 11). How Do Astrocytes Participate in Neural Plasticity? Cold Spring Harbor perspectives in biology.
• 1. Fujita T
  2. Chen MJ
  3. Li B
  4. Smith NA
  5. Peng W
  6. Sun W
  7. Toner MJ
  8. Kress BT
  9. Wang L
  10. Benraiss A
  11. Takano T
  12. Wang S
  13. Nedergaard M
  (2014 Dec 10). Neuronal transgene expression in dominant-negative SNARE mice. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Iliff JJ
  2. Chen MJ
  3. Plog BA
  4. Zeppenfeld DM
  5. Soltero M
  6. Yang L
  7. Singh I
  8. Deane R
  9. Nedergaard M
  (2014 Dec 03). Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience.
• 1. Kress BT
  2. Iliff JJ
  3. Xia M
  4. Wang M
  5. Wei HS
  6. Zeppenfeld D
  7. Xie L
  8. Kang H
  9. Xu Q
  10. Liew JA
  11. Plog BA
  12. Ding F
  13. Deane R
  14. Nedergaard M
  (2014 Dec). Impairment of paravascular clearance pathways in the aging brain. Annals of neurology.
• 1. Cotrina ML
  2. Chen M
  3. Han X
  4. Iliff J
  5. Ren Z
  6. Sun W
  7. Hagemann T
  8. Goldman J
  9. Messing A
  10. Nedergaard M
  (2014 Sep 25). Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease. Brain research.
• 1. Xavier AL
  2. Menezes JR
  3. Goldman SA
  4. Nedergaard M
  (2014 Oct 19). Fine-tuning the central nervous system: microglial modelling of cells and synapses. Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
• 1. Verkhratsky A
  2. Nedergaard M
  (2014 Oct 19). Astroglial cradle in the life of the synapse. Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
• 1. Thrane AS
  2. Rangroo Thrane V
  3. Nedergaard M
  (2014 Sep 15). Drowning stars: reassessing the role of astrocytes in brain edema. Trends in neurosciences.
• 1. Verkhratsky A
  2. Nedergaard M
  3. Hertz L
  (2014 Aug 12). Why are Astrocytes Important? Neurochemical research.
• 1. Tong J
  2. Ren Y
  3. Wang X
  4. Dimopoulos VG
  5. Kesler HN
  6. Liu W
  7. He X
  8. Nedergaard M
  9. Huang JH
  (2014 Jul). Assessment of Nogo-66 receptor 1 function in vivo after spinal cord injury. Neurosurgery.