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Illustration of neurons

The Science of Neuro-Glia Interaction

Welcome to the Science of Neuro-Glia Interaction Lab

My research program focuses on neuroglia interactions. Specifically, my lab studies how neuromodulators mediate the unique interactions between neurons, astrocytes, and microglia in healthy brains and how disruptions in neuronal-glial crosstalk contribute to ADHD, epilepsy, and insulin resistance. My research program is supported by the NIH, NSF, and DOD. 

Lab Members

Nathan A. Smith, M.S., Ph.D.

Nathan A. Smith, M.S., Ph.D.
Principal Investigator


graph of sodium channel data

Astrocytes modulate synaptic plasticity via Norepinephrine

image of nodes of ranvier

NCS-FR: Protecting the Aging Brain: Self-Organizing Networks and Multi-Scale Dynamics Under Energy Constraints

image of spinal motor neuron

Role of astrocytes in Ca2+-dependent microglia modulation of synaptic plasticity 

Florescent image of Optic Nerve

Identification of biomarkers for biochemical pathophysiological and neurological effects of high ammonia

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  Nathan Smith Lab
The Science of Neuro-Glia Interaction