URMC / Labs / Rand Lab / Publications Publications Caito SWJackson BPPunshon TScrimale TGrier AGill SRLove TMWatson GEvan Wijngaarden ERand MD (2017 Nov 14). Variation in Methylmercury Metabolism and Elimination Status (MerMES) in Humans Following Fish Consumption. Toxicological sciences : an official journal of the Society of Toxicology. Prince LMRand MD (2017 Nov 02). Methylmercury exposure causes a persistent inhibition of myogenin expression and C2C12 myoblast differentiation. Toxicology. Llop STran VBallester FBarbone FSofianou-Katsoulis ASunyer JEngström KAlhamdow ALove TMWatson GEBustamante MMurcia MIñiguez CShamlaye CFRosolen VMariuz MHorvat MTratnik JSMazej Dvan Wijngaarden EDavidson PWMyers GJRand MDBroberg K (2017 May 09). CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment. Environment international. Vorojeikina DBroberg KLove TMDavidson PWvan Wijngaarden ERand MD (2017 Feb 10). Glutathione S-Transferase Activity Moderates Methylmercury Toxicity During Development in Drosophila. Toxicological sciences : an official journal of the Society of Toxicology. Engström KLove TMWatson GEZareba GYeates AWahlberg KAlhamdow AThurston SWMulhern MMcSorley EMStrain JJDavidson PWShamlaye CFMyers GJRand MDvan Wijngaarden EBroberg K (2016 Jun 2). Polymorphisms in ATP-binding cassette transporters associated with maternal methylmercury disposition and infant neurodevelopment in mother-infant pairs in the Seychelles Child Development Study. Environment international. Rand MDVorojeikina Dvan Wijngaarden EJackson BPScrimale TZareba GLove TMMyers GJWatson G (2015 Nov 15). Methods for individualized determination of methylmercury elimination rate and de-methylation status in humans following fish consumption. Toxicological sciences : an official journal of the Society of Toxicology. Prince LKorbas MDavidson PBroberg KRand MD (2014 Aug 1). Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury. Toxicological sciences : an official journal of the Society of Toxicology. Engel GLRand MD (2014 May). The Notch target E(spl)mδ is a muscle-specific gene involved in methylmercury toxicity in motor neuron development. Neurotoxicology and teratology. Rand MDMontgomery SLPrince LVorojeikina D (2014). Developmental toxicity assays using the Drosophila model. Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.]. Rand MD (2014). A method of permeabilization of Drosophila embryos for assays of small molecule activity. Journal of visualized experiments : JoVE. Montgomery SLVorojeikina DHuang WMackay TFAnholt RRRand MD (2014). Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myogenic and neuromuscular developmental pathways. PloS one. Jebbett NJHamilton JWRand MDEckenstein F (2013 Sep). Low level methylmercury enhances CNTF-evoked STAT3 signaling and glial differentiation in cultured cortical progenitor cells. Neurotoxicology. Rand MDLowe JAMahapatra CT (2012 Oct 9). Drosophila CYP6g1 and its human homolog CYP3A4 confer tolerance to methylmercury during development. Toxicology. Mahapatra CTRand MD (2012 Jul). Methylmercury tolerance is associated with the humoral stress factor gene Turandot A. Neurotoxicology and teratology. Engel GLDelwig ARand MD (2012 Apr). The effects of methylmercury on Notch signaling during embryonic neural development in Drosophila melanogaster. Toxicology in vitro : an international journal published in association with BIBRA. Rand MDKearney ALDao JClason T (2010 Nov). Permeabilization of Drosophila embryos for introduction of small molecules. Insect biochemistry and molecular biology. Mahapatra CTBond JRand DMRand MD (2010 Jul). Identification of methylmercury tolerance gene candidates in Drosophila. Toxicological sciences : an official journal of the Society of Toxicology. Rand MD (2010 Jan). Drosophotoxicology: the growing potential for Drosophila in neurotoxicology. Neurotoxicology and teratology. Rand MDDao JCClason TA (2009 Sep). Methylmercury disruption of embryonic neural development in Drosophila. Neurotoxicology. Rand MDBland CEBond J (2008 Jul). Methylmercury activates enhancer-of-split and bearded complex genes independent of the notch receptor. Toxicological sciences : an official journal of the Society of Toxicology. Delwig ARand MD (2008 Jul). Kuz and TACE can activate Notch independent of ligand. Cellular and molecular life sciences : CMLS. Cornbrooks CBland CWilliams DWTruman JWRand MD (2007 Jan). Delta expression in post-mitotic neurons identifies distinct subsets of adult-specific lineages in Drosophila. Developmental neurobiology. Bland CRand MD (2006 Dec). Methylmercury induces activation of Notch signaling. Neurotoxicology. Delwig ABland CBeem-Miller MKimberly PRand MD (2006 May 1). Endocytosis-independent mechanisms of Delta ligand proteolysis. Experimental cell research. Bland CEKimberly PRand MD (2003 Apr 18). Notch-induced proteolysis and nuclear localization of the Delta ligand. The Journal of biological chemistry. Mishra-Gorur KRand MDPerez-Villamil BArtavanis-Tsakonas S (2002 Oct 28). Down-regulation of Delta by proteolytic processing. The Journal of cell biology. Rand MDGrimm LMArtavanis-Tsakonas SPatriub VBlacklow SCSklar JAster JC (2000 Mar). Calcium depletion dissociates and activates heterodimeric notch receptors. Molecular and cellular biology. Artavanis-Tsakonas SRand MDLake RJ (1999 Apr 30). Notch signaling: cell fate control and signal integration in development. Science (New York, N.Y.). Qi HRand MDWu XSestan NWang WRakic PXu TArtavanis-Tsakonas S (1999 Jan 1). Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (New York, N.Y.). Rand MDLindblom ACarlson JVilloutreix BOStenflo J (1997 Oct). Calcium binding to tandem repeats of EGF-like modules. Expression and characterization of the EGF-like modules of human Notch-1 implicated in receptor-ligand interactions. Protein science : a publication of the Protein Society. Rand MDLock JBvan't Veer CGaffney DPMann KG (1996 Nov 1). Blood clotting in minimally altered whole blood. Blood. Rand MDHanson SRMann KG (1995 Oct 1). Factor V turnover in a primate model. Blood. Murray JMRand MDEgan JOMurphy SKim HCMann KG (1995 Sep 1). Factor VNew Brunswick: Ala221-to-Val substitution results in reduced cofactor activity. Blood. Kalafatis MBertina RMRand MDMann KG (1995 Feb 24). Characterization of the molecular defect in factor VR506Q. The Journal of biological chemistry. Kalafatis MRand MDMann KG (1994 Dec 16). The mechanism of inactivation of human factor V and human factor Va by activated protein C. The Journal of biological chemistry. Kalafatis MSwords NARand MDMann KG (1994 Nov 29). Membrane-dependent reactions in blood coagulation: role of the vitamin K-dependent enzyme complexes. Biochimica et biophysica acta. Rand MDKalafatis MMann KG (1994 Apr 15). Platelet coagulation factor Va: the major secretory platelet phosphoprotein. Blood. Kalafatis MRand MDMann KG (1994 Jan 18). Factor Va-membrane interaction is mediated by two regions located on the light chain of the cofactor. Biochemistry. Kalafatis MRand MDJenny RJEhrlich YHMann KG (1993 Feb 1). Phosphorylation of factor Va and factor VIIIa by activated platelets. Blood. Kalafatis MKrishnaswamy SRand MDMann KG (1993). Factor V. Methods in enzymology.