Recent Publications

• 1. Lazaro-Pena MI
  2. Ward ZC
  3. Yang S
  4. Strohm A
  5. Merrill AK
  6. Soto CA
  7. Samuelson AV
  HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network.; Frontiers in aging; Vol 3, pp. 861686. 2022 Jul 08.
• 1. Cornwell A
  2. Llop JR
  3. Salzman P
  4. Rasmussen N
  5. Thakar J
  6. Samuelson AV
  The Replica Set Method is a Robust, Accurate, and High-Throughput Approach for Assessing and Comparing Lifespan in C. elegans Experiments.; Frontiers in aging; Vol 3, pp. 861701. 2022 Apr 28.
• 1. Lazaro-Pena MI
  2. Cornwell AB
  3. Samuelson AV
  Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans.; Journal of visualized experiments : JoVE. 2021 Sep 07.
• 1. Cornwell AB
  2. Samuelson AV
  Analysis of Lifespan in C. elegans: Low- and High-Throughput Approaches.; Aging: Methods and Protocols. 2020 Jan 01.
• 1. Lazaro-Pena MI
  2. Merrill AK
  3. Strohm A
  4. Soto CA
  5. Samuelson AV
  At a Therapeutic Crossroad: Targeting HSF1 and Proteostasis in the Treatment of Cancer and Neurodegenerative Diseases; Heat Shock Factors. 2020 Jan 01.
• 1. Lazaro-Pena MI
  2. Cornwell AB
  3. Samuelson AV
  Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans; J Vis Exp. 2020 Jan 01.
• 1. Cornwell AB
  2. Llop JR
  3. Salzman P
  4. Thakar J
  5. Samuelson AV
  The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan.; Journal of visualized experiments : JoVE. 2018 Jun 29.
• 1. Das R
  2. Melo JA
  3. Thondamal M
  4. Morton EA
  5. Cornwell AB
  6. Crick B
  7. Kim JH
  8. Swartz EW
  9. Lamitina T
  10. Douglas PM
  11. Samuelson AV
  The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.; PLoS genetics; Vol 13(10). 2017 Oct.
• 1. Sasaki T
  2. Lian S
  3. Khan A
  4. Llop JR
  5. Samuelson AV
  6. Chen W
  7. Klionsky DJ
  8. Kishi S
  Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase.; Autophagy; Vol 13(2). 2017 Feb.
• 1. Johnson DW
  2. Llop JR
  3. Farrell SF
  4. Yuan J
  5. Stolzenburg LR
  6. Samuelson AV
  The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals.; PLoS genetics; Vol 10(4). 2014 Apr.
• 1. Sykiotis GP
  2. Habeos IG
  3. Samuelson AV
  4. Bohmann D
  The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation.; Current opinion in clinical nutrition and metabolic care; Vol 14(1). 2011 Jan.
• 1. Ruvkun G
  2. Samuelson AV
  3. Carr CE
  4. Curran SP
  5. Shore DE
  Signaling Pathways that Regulate C. elegans Life Span; Research and Perspectives in Endocrine Interactions. 2009 Jan 01.
• 1. Tworkowski KA
  2. Chakraborty AA
  3. Samuelson AV
  4. Seger YR
  5. Narita M
  6. Hannon GJ
  7. Lowe SW
  8. Tansey WP
  Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc.; Proceedings of the National Academy of Sciences of the United States of America; Vol 105(16). 2008 Apr 22.
• 1. Chakraborty AA
  2. Tworkowski KA
  3. Samuelson AV
  4. Seger YR
  5. Narita M
  6. Hannon GJ
  7. Lowe SW
  8. Tansey WP
  Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc; Proc. Natl. Acad. Sci.; Vol 105, pp. 6103-8. 2008 Jan 01.
• 1. Samuelson AV
  2. Carr CE
  3. Ruvkun G
  Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants.; Genes & development; Vol 21(22). 2007 Nov 15.
• 1. Samuelson AV
  2. Carr CE
  3. Ruvkun G
  Gene activities that mediate increased lifespan of C. elegans insulin-like signaling mutants; Genes and Development; Vol 21, pp. 2976-94. 2007 Jan 01.
• 1. Samuelson AV
  2. Klimczak RR
  3. Thompson DB
  4. Carr CE
  5. Ruvkun G
  Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.; Cold Spring Harbor symposia on quantitative biology; Vol 72. 2007.
• 1. Samuelson AV
  2. Narita M
  3. Chan HM
  4. Jin J
  5. de Stanchina E
  6. McCurrach ME
  7. Narita M
  8. Fuchs M
  9. Livingston DM
  10. Lowe SW
  p400 is required for E1A to promote apoptosis.; The Journal of biological chemistry; Vol 280(23). 2005 Jun 10.
• 1. Samuelson AV
  2. Narita M
  3. Chan HM
  4. Jin J
  5. de Stanchina E
  6. McCurrach ME
  7. Narita M
  8. Fuchs M
  9. Livingston DM
  10. Lowe SW
  p400 is required for E1A to promote apoptosis; J. Biol. Chem.; Vol 280, pp. 21915-23. 2005 Jan 01.
• 1. de Stanchina E
  2. McCurrach ME
  3. Zindy F
  4. Shieh SY
  5. Ferbeyre G
  6. Samuelson AV
  7. Prives C
  8. Roussel MF
  9. Sherr CJ
  10. Lowe SW
  E1A signaling to p53 involves the p19(ARF) tumor suppressor.; Genes & development; Vol 12(15). 1998 Aug 01.
• 1. de Stanchina E
  2. McCurrach ME
  3. Zindy F
  4. Shieh SY
  5. Ferbeyre G
  6. Samuelson AV
  7. Prives C
  8. Roussel MF
  9. Sherr CJ
  10. Lowe SW
  E1A signaling to p53 involves the p19(ARF) tumor suppressor; Genes and Development; Vol 12, pp. 2434-42. 1998 Jan 01.
• 1. Samuelson AV
  2. Lowe SW
  Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins.; Proceedings of the National Academy of Sciences of the United States of America; Vol 94(22). 1997 Oct 28.
• 1. Samuelson AA
  2. Lowe SW
  Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins; Proc. Natl. Acad. Sci.; Vol 94, pp. 12094-9. 1997 Jan 01.