URMC / Labs / Samuelson Lab / Publications Recent Publications Zhang YSamuelson AV Antiviral defense in aged Caenorhabditis elegans declines due to loss of DRH-1/RIG-I deSUMOylation via ULP-4/SENP7.; bioRxiv : the preprint server for biology. 2024 Nov 15. Lazaro-Pena MIWard ZCYang SStrohm AMerrill AKSoto CASamuelson AV HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network.; Frontiers in aging; Vol 3, pp. 861686. 2022 Jul 08. Cornwell ALlop JRSalzman PRasmussen NThakar JSamuelson AV The Replica Set Method is a Robust, Accurate, and High-Throughput Approach for Assessing and Comparing Lifespan in C. elegans Experiments.; Frontiers in aging; Vol 3, pp. 861701. 2022 Apr 28. Lazaro-Pena MICornwell ABSamuelson AV Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans.; Journal of visualized experiments : JoVE. 2021 Sep 07. Cornwell ABSamuelson AV Analysis of Lifespan in C. elegans: Low- and High-Throughput Approaches.; Aging: Methods and Protocols. 2020 Jan 01. Lazaro-Pena MIMerrill AKStrohm ASoto CASamuelson AV At a Therapeutic Crossroad: Targeting HSF1 and Proteostasis in the Treatment of Cancer and Neurodegenerative Diseases; Heat Shock Factors. 2020 Jan 01. Lazaro-Pena MICornwell ABSamuelson AV Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans; J Vis Exp. 2020 Jan 01. Cornwell ABLlop JRSalzman PThakar JSamuelson AV The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan.; Journal of visualized experiments : JoVE. 2018 Jun 29. Das RMelo JAThondamal MMorton EACornwell ABCrick BKim JHSwartz EWLamitina TDouglas PMSamuelson AV The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.; PLoS genetics; Vol 13(10). 2017 Oct. Sasaki TLian SKhan ALlop JRSamuelson AVChen WKlionsky DJKishi S Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase.; Autophagy; Vol 13(2). 2017 Feb. Johnson DWLlop JRFarrell SFYuan JStolzenburg LRSamuelson AV The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals.; PLoS genetics; Vol 10(4). 2014 Apr. Sykiotis GPHabeos IGSamuelson AVBohmann D The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation.; Current opinion in clinical nutrition and metabolic care; Vol 14(1). 2011 Jan. Ruvkun GSamuelson AVCarr CECurran SPShore DE Signaling Pathways that Regulate C. elegans Life Span; Research and Perspectives in Endocrine Interactions. 2009 Jan 01. Tworkowski KAChakraborty AASamuelson AVSeger YRNarita MHannon GJLowe SWTansey WP Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc.; Proceedings of the National Academy of Sciences of the United States of America; Vol 105(16). 2008 Apr 22. Chakraborty AATworkowski KASamuelson AVSeger YRNarita MHannon GJLowe SWTansey WP Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc; Proc. Natl. Acad. Sci.; Vol 105, pp. 6103-8. 2008 Jan 01. Samuelson AVCarr CERuvkun G Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants.; Genes & development; Vol 21(22). 2007 Nov 15. Samuelson AVCarr CERuvkun G Gene activities that mediate increased lifespan of C. elegans insulin-like signaling mutants; Genes and Development; Vol 21, pp. 2976-94. 2007 Jan 01. Samuelson AVKlimczak RRThompson DBCarr CERuvkun G Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.; Cold Spring Harbor symposia on quantitative biology; Vol 72. 2007. Samuelson AVNarita MChan HMJin Jde Stanchina EMcCurrach MENarita MFuchs MLivingston DMLowe SW p400 is required for E1A to promote apoptosis.; The Journal of biological chemistry; Vol 280(23). 2005 Jun 10. Samuelson AVNarita MChan HMJin Jde Stanchina EMcCurrach MENarita MFuchs MLivingston DMLowe SW p400 is required for E1A to promote apoptosis; J. Biol. Chem.; Vol 280, pp. 21915-23. 2005 Jan 01. de Stanchina EMcCurrach MEZindy FShieh SYFerbeyre GSamuelson AVPrives CRoussel MFSherr CJLowe SW E1A signaling to p53 involves the p19(ARF) tumor suppressor.; Genes & development; Vol 12(15). 1998 Aug 01. de Stanchina EMcCurrach MEZindy FShieh SYFerbeyre GSamuelson AVPrives CRoussel MFSherr CJLowe SW E1A signaling to p53 involves the p19(ARF) tumor suppressor; Genes and Development; Vol 12, pp. 2434-42. 1998 Jan 01. Samuelson AVLowe SW Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins.; Proceedings of the National Academy of Sciences of the United States of America; Vol 94(22). 1997 Oct 28. Samuelson AALowe SW Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins; Proc. Natl. Acad. Sci.; Vol 94, pp. 12094-9. 1997 Jan 01.