URMC / Labs / Sarelius Lab / Publications Recent Publications Sarelius IHTitus PAMaimon NOkech WWilke-Mounts SJBrennan JRHocking DC Extracellular matrix fibronectin initiates endothelium-dependent arteriolar dilatation via the heparin-binding, matricryptic RWRPK sequence of the first type III repeat of fibrillar fibronectin.; The Journal of physiology; Vol 594(3). 2016 Feb 1. Murrant CLSarelius IH Local control of blood flow during active hyperaemia: what kinds of integration are important?; The Journal of physiology; Vol 593(21). 2015 Nov 1. Sarelius IHGlading AJ Control of vascular permeability by adhesion molecules.; Tissue barriers; Vol 3(1-2). 2015. Rocheleau ADSumagin RSarelius IHKing MR Simulation and Analysis of Tethering Behavior of Neutrophils with Pseudopods.; PloS one; Vol 10(6). 2015. DiStefano PVKuebel JMSarelius IHGlading AJ KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling.; The Journal of biological chemistry; Vol 289(47). 2014 Nov 21. Maimon NTitus PASarelius IH Pre-exposure to adenosine, acting via A(2A) receptors on endothelial cells, alters the protein kinase A dependence of adenosine-induced dilation in skeletal muscle resistance arterioles.; The Journal of physiology; Vol 592(12). 2014 Jun 15. Sumagin RSarelius IH Emerging understanding of roles for arterioles in inflammation.; Microcirculation (New York, N.Y. : 1994); Vol 20(8). 2013 Nov. Corr MLerman IKeubel JMRonacher LMisra RLund FSarelius IHGlading AJ Decreased Krev interaction-trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo.; Arteriosclerosis, thrombosis, and vascular biology; Vol 32(11). 2012 Nov. Hyun YMSumagin RSarangi PPLomakina EOverstreet MGBaker CMFowell DJWaugh RESarelius IHKim M Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels.; The Journal of experimental medicine; Vol 209(7). 2012 Jul 2. Sumagin RKuebel JMSarelius IH Leukocyte rolling and adhesion both contribute to regulation of microvascular permeability to albumin via ligation of ICAM-1.; American journal of physiology. Cell physiology; Vol 301(4). 2011 Oct. Sumagin RPrizant HLomakina EWaugh RESarelius IH LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ.; Journal of immunology (Baltimore, Md. : 1950); Vol 185(11). 2010 Dec 1. Sarelius IPohl U Control of muscle blood flow during exercise: local factors and integrative mechanisms.; Acta physiologica (Oxford, England); Vol 199(4). 2010 Aug. Sumagin RSarelius IH Intercellular adhesion molecule-1 enrichment near tricellular endothelial junctions is preferentially associated with leukocyte transmigration and signals for reorganization of these junctions to accommodate leukocyte passage.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(9). 2010 May 1. Sumagin RLamkin-Kennard KASarelius IH A separate role for ICAM-1 and fluid shear in regulating leukocyte interactions with straight regions of venular wall and venular convergences.; Microcirculation (New York, N.Y. : 1994); Vol 16(6). 2009 Aug. Lee JJirapatnakul ACReeves APCrowe WESarelius IH Vessel diameter measurement from intravital microscopy.; Annals of biomedical engineering; Vol 37(5). 2009 May. Sumagin RLomakina ESarelius IH Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling.; American journal of physiology. Heart and circulatory physiology; Vol 295(3). 2008 Sep. Sumagin RBrown CWSarelius IHKing MR Microvascular endothelial cells exhibit optimal aspect ratio for minimizing flow resistance.; Annals of biomedical engineering; Vol 36(4). 2008 Apr. Hocking DCTitus PASumagin RSarelius IH Extracellular matrix fibronectin mechanically couples skeletal muscle contraction with local vasodilation.; Circulation research; Vol 102(3). 2008 Feb 15. Sumagin RSarelius IH A role for ICAM-1 in maintenance of leukocyte-endothelial cell rolling interactions in inflamed arterioles.; American journal of physiology. Heart and circulatory physiology; Vol 293(5). 2007 Nov. Huxley VHWang JJSarelius IH Adaptation of coronary microvascular exchange in arterioles and venules to exercise training and a role for sex in determining permeability responses.; American journal of physiology. Heart and circulatory physiology; Vol 293(2). 2007 Aug. Sumagin RSarelius IH TNF-alpha activation of arterioles and venules alters distribution and levels of ICAM-1 and affects leukocyte-endothelial cell interactions.; American journal of physiology. Heart and circulatory physiology; Vol 291(5). 2006 Nov. Sarelius IHKuebel JMWang JHuxley VH Macromolecule permeability of in situ and excised rodent skeletal muscle arterioles and venules.; American journal of physiology. Heart and circulatory physiology; Vol 290(1). 2006 Jan. Wojciechowski JCSarelius IH Preferential binding of leukocytes to the endothelial junction region in venules in situ.; Microcirculation (New York, N.Y. : 1994); Vol 12(4). 2005 Jun. Lamkin-Kennard KAChuang JYKim MBSarelius IHKing MR The distribution of rolling neutrophils in venular convergences.; Biorheology; Vol 42(5). 2005. Sarelius IHKuebel JMHuxley VH Solute permeability of in situ skeletal muscle microvessels (Abstract); Faseb Journal; Vol 19. 2005 Jan 01. Kim MBSarelius IH Role of shear forces and adhesion molecule distribution on P-selectin-mediated leukocyte rolling in postcapillary venules.; American journal of physiology. Heart and circulatory physiology; Vol 287(6). 2004 Dec. Duza TSarelius IH Localized transient increases in endothelial cell Ca2+ in arterioles in situ: implications for coordination of vascular function.; American journal of physiology. Heart and circulatory physiology; Vol 286(6). 2004 Jun. King MRBansal DKim MBSarelius IH The effect of hematocrit and leukocyte adherence on flow direction in the microcirculation.; Annals of biomedical engineering; Vol 32(6). 2004 Jun. Duza TSarelius IH Increase in endothelial cell Ca(2+) in response to mouse cremaster muscle contraction.; The Journal of physiology; Vol 555(Pt 2). 2004 Mar 1. Murrant CLDuza TKim MBCohen KDSarelius IH Arteriolar dilations induced by contraction of hamster cremaster muscle are dependent on changes in endothelial cell calcium.; Acta physiologica Scandinavica; Vol 180(3). 2004 Mar. Kim MBSarelius IH Regulation of leukocyte recruitment by local wall shear rate and leukocyte delivery.; Microcirculation (New York, N.Y. : 1994); Vol 11(1). 2004 Jan. King MRKim MBSarelius IHHammer DA Hydrodynamic interactions between rolling leukocytes in vivo.; Microcirculation (New York, N.Y. : 1994); Vol 10(5). 2003 Oct. Duza TSarelius IH Conducted dilations initiated by purines in arterioles are endothelium dependent and require endothelial Ca2+.; American journal of physiology. Heart and circulatory physiology; Vol 285(1). 2003 Jul. Kim MBSarelius IH Distributions of wall shear stress in venular convergences of mouse cremaster muscle.; Microcirculation (New York, N.Y. : 1994); Vol 10(2). 2003 Apr. Murrant CLSarelius IH Multiple dilator pathways in skeletal muscle contraction-induced arteriolar dilations.; American journal of physiology. Regulatory, integrative and comparative physiology; Vol 282(4). 2002 Apr. Cohen KDSarelius IH Muscle contraction under capillaries in hamster muscle induces arteriolar dilatation via K(ATP) channels and nitric oxide.; The Journal of physiology; Vol 539(Pt 2). 2002 Mar 1. Frame MDSarelius IH Flow-induced cytoskeletal changes in endothelial cells growing on curved surfaces.; Microcirculation (New York, N.Y. : 1994); Vol 7(6 Pt 1). 2000 Dec. Murrant CLSarelius IH Local and remote arteriolar dilations initiated by skeletal muscle contraction.; American journal of physiology. Heart and circulatory physiology; Vol 279(5). 2000 Nov. Murdock RCReynolds CSarelius IHWaugh RE Adaptation and survival of surface-deprived red blood cells in mice.; American journal of physiology. Cell physiology; Vol 279(4). 2000 Oct. Sarelius IHCohen KDMurrant CL Role for capillaries in coupling blood flow with metabolism.; Clinical and experimental pharmacology & physiology; Vol 27(10). 2000 Oct. Cohen KDBerg BRSarelius IH Remote arteriolar dilations in response to muscle contraction under capillaries.; American journal of physiology. Heart and circulatory physiology; Vol 278(6). 2000 Jun. Murrant CLSarelius IH Coupling of muscle metabolism and muscle blood flow in capillary units during contraction.; Acta physiologica Scandinavica; Vol 168(4). 2000 Apr. Lau KSGrange RWIsotani ESarelius IHKamm KEHuang PLStull JT nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle.; Physiological genomics; Vol 2(1). 2000 Jan 24. Lau KSGrange RWChang WJKamm KESarelius IStull JT Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide.; FEBS letters; Vol 431(1). 1998 Jul 10. Frame MDChapman GBMakino YSarelius IH Shear stress gradient over endothelial cells in a curved microchannel system.; Biorheology; Vol 35(4-5). 1998 Jul. Berg BRCohen KDSarelius IH Direct coupling between blood flow and metabolism at the capillary level in striated muscle.; The American journal of physiology; Vol 272(6 Pt 2). 1997 Jun. Berg BRSarelius IH Erythrocyte flux in capillary networks during maturation: implications for oxygen delivery.; The American journal of physiology; Vol 271(6 Pt 2). 1996 Dec. Waugh RESarelius IH Effects of lost surface area on red blood cells and red blood cell survival in mice.; The American journal of physiology; Vol 271(6 Pt 1). 1996 Dec. Frame MDSarelius IH Endothelial cell dilatory pathways link flow and wall shear stress in an intact arteriolar network.; Journal of applied physiology (Bethesda, Md. : 1985); Vol 81(5). 1996 Nov. Frame MDSarelius IH Vascular communication and endothelial cell function in the control of arteriolar flow distribution.; Microcirculation (New York, N.Y. : 1994); Vol 3(2). 1996 Jun.