URMC / Labs / Sarelius Lab / Publications Recent Publications Sarelius IHTitus PAMaimon NOkech WWilke-Mounts SJBrennan JRHocking DC (2016 Feb 1). Extracellular matrix fibronectin initiates endothelium-dependent arteriolar dilatation via the heparin-binding, matricryptic RWRPK sequence of the first type III repeat of fibrillar fibronectin. The Journal of physiology. Murrant CLSarelius IH (2015 Nov 1). Local control of blood flow during active hyperaemia: what kinds of integration are important? The Journal of physiology. Sarelius IHGlading AJ (2015). Control of vascular permeability by adhesion molecules. Tissue barriers. Rocheleau ADSumagin RSarelius IHKing MR (2015). Simulation and Analysis of Tethering Behavior of Neutrophils with Pseudopods. PloS one. DiStefano PVKuebel JMSarelius IHGlading AJ (2014 Nov 21). KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling. The Journal of biological chemistry. Maimon NTitus PASarelius IH (2014 Jun 15). Pre-exposure to adenosine, acting via A(2A) receptors on endothelial cells, alters the protein kinase A dependence of adenosine-induced dilation in skeletal muscle resistance arterioles. The Journal of physiology. Sumagin RSarelius IH (2013 Nov). Emerging understanding of roles for arterioles in inflammation. Microcirculation (New York, N.Y. : 1994). Corr MLerman IKeubel JMRonacher LMisra RLund FSarelius IHGlading AJ (2012 Nov). Decreased Krev interaction-trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo. Arteriosclerosis, thrombosis, and vascular biology. Hyun YMSumagin RSarangi PPLomakina EOverstreet MGBaker CMFowell DJWaugh RESarelius IHKim M (2012 Jul 2). Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels. The Journal of experimental medicine. Sumagin RKuebel JMSarelius IH (2011 Oct). Leukocyte rolling and adhesion both contribute to regulation of microvascular permeability to albumin via ligation of ICAM-1. American journal of physiology. Cell physiology. Sumagin RPrizant HLomakina EWaugh RESarelius IH (2010 Dec 1). LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ. Journal of immunology (Baltimore, Md. : 1950). Sarelius IPohl U (2010 Aug). Control of muscle blood flow during exercise: local factors and integrative mechanisms. Acta physiologica (Oxford, England). Sumagin RSarelius IH (2010 May 1). Intercellular adhesion molecule-1 enrichment near tricellular endothelial junctions is preferentially associated with leukocyte transmigration and signals for reorganization of these junctions to accommodate leukocyte passage. Journal of immunology (Baltimore, Md. : 1950). Sumagin RLamkin-Kennard KASarelius IH (2009 Aug). A separate role for ICAM-1 and fluid shear in regulating leukocyte interactions with straight regions of venular wall and venular convergences. Microcirculation (New York, N.Y. : 1994). Lee JJirapatnakul ACReeves APCrowe WESarelius IH (2009 May). Vessel diameter measurement from intravital microscopy. Annals of biomedical engineering. Sumagin RLomakina ESarelius IH (2008 Sep). Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling. American journal of physiology. Heart and circulatory physiology. Sumagin RBrown CWSarelius IHKing MR (2008 Apr). Microvascular endothelial cells exhibit optimal aspect ratio for minimizing flow resistance. Annals of biomedical engineering. Hocking DCTitus PASumagin RSarelius IH (2008 Feb 15). Extracellular matrix fibronectin mechanically couples skeletal muscle contraction with local vasodilation. Circulation research. Sumagin RSarelius IH (2007 Nov). A role for ICAM-1 in maintenance of leukocyte-endothelial cell rolling interactions in inflamed arterioles. American journal of physiology. Heart and circulatory physiology. Huxley VHWang JJSarelius IH (2007 Aug). Adaptation of coronary microvascular exchange in arterioles and venules to exercise training and a role for sex in determining permeability responses. American journal of physiology. Heart and circulatory physiology. Sarelius IHKuebel JMWang JHuxley VH (2006 Jan). Macromolecule permeability of in situ and excised rodent skeletal muscle arterioles and venules. American journal of physiology. Heart and circulatory physiology. Wojciechowski JCSarelius IH (2005 Jun). Preferential binding of leukocytes to the endothelial junction region in venules in situ. Microcirculation (New York, N.Y. : 1994). Lamkin-Kennard KAChuang JYKim MBSarelius IHKing MR (2005). The distribution of rolling neutrophils in venular convergences. Biorheology. Kim MBSarelius IH (2004 Dec). Role of shear forces and adhesion molecule distribution on P-selectin-mediated leukocyte rolling in postcapillary venules. American journal of physiology. Heart and circulatory physiology. Duza TSarelius IH (2004 Jun). Localized transient increases in endothelial cell Ca2+ in arterioles in situ: implications for coordination of vascular function. American journal of physiology. Heart and circulatory physiology. King MRBansal DKim MBSarelius IH (2004 Jun). The effect of hematocrit and leukocyte adherence on flow direction in the microcirculation. Annals of biomedical engineering. Duza TSarelius IH (2004 Mar 1). Increase in endothelial cell Ca(2+) in response to mouse cremaster muscle contraction. The Journal of physiology. Murrant CLDuza TKim MBCohen KDSarelius IH (2004 Mar). Arteriolar dilations induced by contraction of hamster cremaster muscle are dependent on changes in endothelial cell calcium. Acta physiologica Scandinavica. Kim MBSarelius IH (2004 Jan). Regulation of leukocyte recruitment by local wall shear rate and leukocyte delivery. Microcirculation (New York, N.Y. : 1994). King MRKim MBSarelius IHHammer DA (2003 Oct). Hydrodynamic interactions between rolling leukocytes in vivo. Microcirculation (New York, N.Y. : 1994). Duza TSarelius IH (2003 Jul). Conducted dilations initiated by purines in arterioles are endothelium dependent and require endothelial Ca2+. American journal of physiology. Heart and circulatory physiology. Kim MBSarelius IH (2003 Apr). Distributions of wall shear stress in venular convergences of mouse cremaster muscle. Microcirculation (New York, N.Y. : 1994). Murrant CLSarelius IH (2002 Apr). Multiple dilator pathways in skeletal muscle contraction-induced arteriolar dilations. American journal of physiology. Regulatory, integrative and comparative physiology. Cohen KDSarelius IH (2002 Mar 1). Muscle contraction under capillaries in hamster muscle induces arteriolar dilatation via K(ATP) channels and nitric oxide. The Journal of physiology. Frame MDSarelius IH (2000 Dec). Flow-induced cytoskeletal changes in endothelial cells growing on curved surfaces. Microcirculation (New York, N.Y. : 1994). Murrant CLSarelius IH (2000 Nov). Local and remote arteriolar dilations initiated by skeletal muscle contraction. American journal of physiology. Heart and circulatory physiology. Murdock RCReynolds CSarelius IHWaugh RE (2000 Oct). Adaptation and survival of surface-deprived red blood cells in mice. American journal of physiology. Cell physiology. Sarelius IHCohen KDMurrant CL (2000 Oct). Role for capillaries in coupling blood flow with metabolism. Clinical and experimental pharmacology & physiology. Cohen KDBerg BRSarelius IH (2000 Jun). Remote arteriolar dilations in response to muscle contraction under capillaries. American journal of physiology. Heart and circulatory physiology. Murrant CLSarelius IH (2000 Apr). Coupling of muscle metabolism and muscle blood flow in capillary units during contraction. Acta physiologica Scandinavica. Lau KSGrange RWIsotani ESarelius IHKamm KEHuang PLStull JT (2000 Jan 24). nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle. Physiological genomics. Lau KSGrange RWChang WJKamm KESarelius IStull JT (1998 Jul 10). Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide. FEBS letters. Frame MDChapman GBMakino YSarelius IH (1998 Jul). Shear stress gradient over endothelial cells in a curved microchannel system. Biorheology. Berg BRCohen KDSarelius IH (1997 Jun). Direct coupling between blood flow and metabolism at the capillary level in striated muscle. The American journal of physiology. Waugh RESarelius IH (1996 Dec). Effects of lost surface area on red blood cells and red blood cell survival in mice. The American journal of physiology. Berg BRSarelius IH (1996 Dec). Erythrocyte flux in capillary networks during maturation: implications for oxygen delivery. The American journal of physiology. Frame MDSarelius IH (1996 Nov). Endothelial cell dilatory pathways link flow and wall shear stress in an intact arteriolar network. Journal of applied physiology (Bethesda, Md. : 1985). Frame MDSarelius IH (1996 Jun). Vascular communication and endothelial cell function in the control of arteriolar flow distribution. Microcirculation (New York, N.Y. : 1994). Waugh REHwang WCSarelius IH (1996). Combined use of fluorescence microscopy and micromechanical measurement to assess cell and membrane properties. Pflügers Archiv : European journal of physiology. Frame MDSarelius IH (1995 Dec). A system for culture of endothelial cells in 20-50-microns branching tubes. Microcirculation (New York, N.Y. : 1994).