URMC / Labs / Schwarz Lab / Publications Publications Bouta EMBell RDRahimi HXing LWood RWBingham CORitchlin CTSchwarz EM (2018 Jan 11). Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis. Nature reviews. Rheumatology. Bell RDRudmann CWood RWSchwarz EMRahimi H (2018). Longitudinal micro-CT as an outcome measure of interstitial lung disease in TNF-transgenic mice. PloS one. Farnsworth CWSchott EMBenvie AMZukoski JKates SLSchwarz EMGill SRZuscik MJMooney RA (2017 Dec 11). Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation and osteolysis during Staphylococcus aureus implant-associated bone infection. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Ishikawa Mde Mesy Bentley KLMcEntire BJBal BSSchwarz EMXie C (2017 Sep 02). Surface Topography of Silicon Nitride Affects Antimicrobial and Osseosintegrative Properties of Tibial Implants in a Murine Model. Journal of biomedical materials research. Part A. Zhang LWang TChang MKaiser CKim JDWu TCao XZhang XSchwarz EM (2017 May 30). Teriparatide treatment improves bone defect healing via anabolic effects on new bone formation and non-anabolic effects on inhibition of mast cells in a murine cranial window model. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Schwarz EM (2017 Apr 19). Confirmation of Sexual Dimorphisms in Metal Hypersensitivity and Joint Pain Following Total Joint Arthroplasty: Commentary on an article by Marco S. Caicedo, PhD, et al.: "Females with Unexplained Joint Pain Following Total Joint Arthroplasty Exhibit a Higher Rate and Severity of Hypersensitivity to Implant Metals Compared with Males. Implications of Sex-Based Bioreactivity Differences". The Journal of bone and joint surgery. American volume. Farnsworth CWSchott EMJensen SEZukoski JBenvie AMRefaai MAKates SLSchwarz EMZuscik MJGill SRMooney RA (2017 Mar 20). Adaptive upregulation of Clumping Factor A (ClfA) by S. aureus in the obese, type 2 diabetic host mediates increased virulence. Infection and immunity. Chen XWang ZDuan NZhu GSchwarz EMXie C (2017 Feb 08). Osteoblast-osteoclast interactions. Connective tissue research. Bouta EMKuzin Ide Mesy Bentley KWood RWRahimi HJi RCRitchlin CTBottaro AXing LSchwarz EM (2017 Jan 24). Treatment of Tumor Necrosis Factor-Transgenic Mice With Anti-Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress. Arthritis & rheumatology (Hoboken, N.J.). Peng JRen YHe WLi ZYang JLiu YZheng ZKates SLSchwarz EMXie CXu Y (2017). Epidemiological, Clinical and Microbiological Characteristics of Patients with Post-Traumatic Osteomyelitis of Limb Fractures in Southwest China: A Hospital-Based Study. Journal of bone and joint infection. Xu HBouta EMWood RWSchwarz EMWang YXing L (2017). Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis. Bone research. Nishitani KMietus ZBeck CAIto HMatsuda SAwad HAEhrhart NSchwarz EM (2017). High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model. PloS one. de Mesy Bentley KLTrombetta RNishitani KBello-Irizarry SNNinomiya MZhang LChung HLMcGrath JLDaiss JLAwad HAKates SLSchwarz EM (2016 Dec 08). Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Trombetta RInzana JASchwarz EMKates SLAwad HA (2016 Jun 20). 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery. Annals of biomedical engineering. Chen YHallab NJLiao YSNarayan VSchwarz EMXie C (2016 May). Antioxidant impregnated ultra-high molecular weight polyethylene wear debris particles display increased bone remodeling and a superior osteogenic:osteolytic profile vs. conventional UHMWPE particles in a murine calvaria model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Kuzin IIKates SLJu YZhang LRahimi HWojciechowski WBernstein SHBurack RSchwarz EMBottaro A (2016 Apr 23). Increased numbers of CD23(+) CD21(hi) Bin-like B cells in human reactive and rheumatoid arthritis lymph nodes. European journal of immunology. Moriarty TFKuehl RCoenye TMetsemakers WJMorgenstern MSchwarz EMRiool MZaat SAJKhana NKates SLRichards RG (2016 Apr). Orthopaedic device-related infection: current and future interventions for improved prevention and treatment. EFORT open reviews. Liang QJu YChen YWang WLi JZhang LXu HWood RWSchwarz EMBoyce BFWang YXing L (2016 Mar 12). Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice. Arthritis research & therapy. Inzana JASchwarz EMKates SLAwad HA (2016 Mar). Biomaterials approaches to treating implant-associated osteomyelitis. Biomaterials. Antebi BZhang LSheyn DPelled GZhang XGazit ZSchwarz EMGazit D (2016 Mar). Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts. Bioengineering. Sheyn DShapiro GTawackoli WJun DSKoh YKang KBSu SDa XBen-David SBez MYalon EAntebi BAvalos PStern TZelzer ESchwarz EMGazit ZPelled GBae HMGazit D (2016 Feb). PTH Induces Systemically Administered Mesenchymal Stem Cells to Migrate to and Regenerate Spine Injuries. Molecular therapy : the journal of the American Society of Gene Therapy. Sheyn DShapiro GTawackoli WJun DSKoh YKang KBSu SDa XBen-David SBez MYalon EAntebi BAvalos PStern TZelzer ESchwarz EMGazit ZPelled GBae HMGazit D (2016 Feb). PTH Induces Systemically Administered Mesenchymal Stem Cells to Migrate to and Regenerate Spine Injuries. Molecular therapy : the journal of the American Society of Gene Therapy. Antebi BZhang LSheyn DPelled GZhang XGazit ZSchwarz EMGazit D (2016 Jan 11). Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts. Bioengineering (Basel, Switzerland). Zhang LChang MBeck CASchwarz EMBoyce BF (2016). Analysis of new bone, cartilage, and fibrosis tissue in healing murine allografts using whole slide imaging and a new automated histomorphometric algorithm. Bone research. Rahimi HBell RBouta EMWood RWXing LRitchlin CTSchwarz EM (2016). Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential. Arthritis research & therapy. Rahimi HDieudonne GKheyfits VBouta EMWood RWBarrett RMoorehead SSchwarz EMRitchlin CT (2016). Relationship Between Lymph Node Volume and Pain Following Certolizumab Therapy for Rheumatoid Arthritis Flare: A Pilot Study. Clinical medicine insights. Arthritis and musculoskeletal disorders. Nishitani KSutipornpalangkul Wde Mesy Bentley KLVarrone JJBello-Irizarry SNIto HMatsuda SKates SLDaiss JLSchwarz EM (2015 Sep). Quantifying the natural history of biofilm formation in vivo during the establishment of chronic implant-associated Staphylococcus aureus osteomyelitis in mice to identify critical pathogen and host factors. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Nishitani KBeck CARosenberg AFKates SLSchwarz EMDaiss JL (2015 Sep). A Diagnostic Serum Antibody Test for Patients With Staphylococcus aureus Osteomyelitis. Clinical orthopaedics and related research. Xie CLi YLi QChen YYao JYin GBi QO'Keefe RJSchwarz EMTyler W (2015 Sep). Increased Insulin mRNA Binding Protein-3 Expression Correlates with Vascular Enhancement of Renal Cell Carcinoma by Intravenous Contrast-CT and is Associated with Bone Metastasis. Journal of bone oncology. Kuzin IIBouta EMSchwarz EMBottaro A (2015 Aug). TNF signals are dispensable for the generation of CD23+ CD21/35-high CD1d-high B cells in inflamed lymph nodes. Cellular immunology. Farnsworth CWShehatou CTMaynard RNishitani KKates SLZuscik MJSchwarz EMDaiss JLMooney RA (2015 Jun). A humoral immune defect distinguishes the response to Staphylococcus aureus infections in mice with obesity and type 2 diabetes from that in mice with type 1 diabetes. Infection and immunity. Zhang MFeigenson MSheu TJAwad HASchwarz EMJonason JHLoiselle AEO'Keefe RJ (2015 Mar). Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength. Bone. Inzana JASchwarz EMKates SLAwad HA (2015 Mar). A novel murine model of established Staphylococcal bone infection in the presence of a fracture fixation plate to study therapies utilizing antibiotic-laden spacers after revision surgery. Bone. Farhat YMAl-Maliki AAEasa AO'Keefe RJSchwarz EMAwad HA (2015 Feb). TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair. Journal of cellular physiology. Bouta EMLi JJu YBrown EBRitchlin CTXing LSchwarz EM (2015 Jan 15). The Role of the Lymphatic System in Inflammatory-Erosive Arthritis. Seminars in cell & developmental biology. Inzana JATrombetta RPSchwarz EMKates SLAwad HA (2015). 3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection. European cells & materials. Bouta EMBanik PDWood RWRahimi HRitchlin CTThiele RGSchwarz EM (2014 Oct 31). Validation of Power Doppler Versus Contrast Enhanced Magnetic Resonance Imaging Quantification of Joint Inflammation in Murine Inflammatory Arthritis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Varrone JJde Mesy Bentley KLBello-Irizarry SNNishitani KMack SHunter JGKates SLDaiss JLSchwarz EM (2014 Oct). Passive immunization with anti-glucosaminidase monoclonal antibodies protects mice from implant-associated osteomyelitis by mediating opsonophagocytosis of Staphylococcus aureus megaclusters. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Papuga MOBeck CAKates SLSchwarz EMMaloney MD (2014 Jun). Validation of GAITRite and PROMIS as high-throughput physical function outcome measures following ACL reconstruction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Yukata KXie CLi TFTakahata MHoak DKondabolu SZhang XAwad HASchwarz EMBeck CAJonason JHO'Keefe RJ (2014 May). Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment. Bone. Inzana JAOlvera DFuller SMKelly JPGraeve OASchwarz EMKates SLAwad HA (2014 Apr). 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. Biomaterials. Bouta EMWood RWBrown EBRahimi HRitchlin CTSchwarz EM (2014 Mar 15). In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. The Journal of physiology. Long TZhu ZAwad HASchwarz EMHilton MJDong Y (2014 Mar). The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice. Biomaterials. Nishitani KSchwarz EM (2014 Mar). Regenerative medicine: Cartilage transplants hold promise for challenging bone defects. Nature reviews. Rheumatology. Dhillon RSZhang LSchwarz EMBoyce BFXie C (2014). The murine femoral bone graft model and a semiautomated histomorphometric analysis tool. Methods in molecular biology (Clifton, N.J.). Hasslund SDadali TUlrich-Vinther MSøballe KSchwarz EMAwad HA (2014). Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions. Journal of tissue engineering. Schwarz EMKates SLAlt V (2014 Jan). The 1st International Consensus Meeting on Periprosthetic Joint Infection. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Rosenberg AFan HChiu YGBolce RTabechian DBarrett RMoorehead SBaribaud FLiu HPeffer NShealy DSchwarz EMRitchlin CT (2014). Divergent gene activation in peripheral blood and tissues of patients with rheumatoid arthritis, psoriatic arthritis and psoriasis following infliximab therapy. PloS one. Gao LSheu TJDong YHoak DMZuscik MJSchwarz EMHilton MJO'Keefe RJJonason JH (2013 Dec 15). TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. Journal of cell science. Gedbjerg NLaRosa RHunter JGVarrone JJKates SLSchwarz EMDaiss JL (2013 Nov 20). Anti-glucosaminidase IgG in sera as a biomarker of host immunity against Staphylococcus aureus in orthopaedic surgery patients. The Journal of bone and joint surgery. American volume.