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Ann Regina Falsey, M.D.

Ann Regina Falsey, M.D.

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About Me

Faculty Appointments

Professor - Department of Medicine, Infectious Diseases (SMD)

Credentials

Post-doctoral Training & Residency

Fellowship, Infectious Disease, University of Rochester Medical Center. 1988 - 1991

Fellowship, Infectious Disease, Yale New Haven Hospital Temple Medical Center. 1987 - 1988

Residency, Internal Medicine, University of Rochester Medical Center. 1984 - 1986

Internship, Internal Medicine, University of Rochester Medical Center. 1983 - 1984

Education

MD | Vanderbilt University School of Medicine. 1983

Research

Dr Falsey is a Professor of Medicine at the University Of Rochester School Of Medicine.
The focus of her research has been clinical and translational research in the field of respiratory viral infections in adults. Dr Falsey received her Bachelor of Science degree in Biology at Providence Colleg...
Dr Falsey is a Professor of Medicine at the University Of Rochester School Of Medicine.
The focus of her research has been clinical and translational research in the field of respiratory viral infections in adults. Dr Falsey received her Bachelor of Science degree in Biology at Providence College and Doctorate in Medicine at Vanderbilt University School of Medicine. She completed her residency in Internal Medicine at Strong Memorial Hospital at the University of Rochester and infectious disease fellowship at Yale University and the University of Rochester. Initially the focus of her research was defining the epidemiology and impact of respiratory syncytial virus in adult populations. More recently, Dr Falsey has broadened her research to include numerous viral respiratory pathogens including influenza, coronaviruses, parainfluenza viruses and human metapneumovirus. She has conducted numerous adult surveillance and vaccine studies in a variety of settings including ambulatory older adult clinics, nursing homes and senior daycare centers. She has extensive experience in the development and performance of diagnostic and serologic assays for influenza and other respiratory viruses including cell culture, RT-PCR, EIA and neutralization assays. Dr Falsey has been a standing member of the Clinical Studies and Field Research Study Section and has served as an ad hoc reviewer for numerous NIH study section reviews. She is a member of the steering committee for the Global Influenza Initiative, the Infectious Diseases Society of America and the American Virology Society. Dr Falsey has published over 200 peer reviewed articles, reviews, book chapters and abstracts.

Clinical Trials

A Phase 3 Study to Evaluate the Immunogenicity and Safety of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in High-Risk Adults

Lead Researcher: Ann Regina Falsey

RSV is a virus that causes respiratory tract infections, which affect the lungs. RSV symptoms include runny nose, stuffy nose, wheezing, cough, sore throat, fever, and shortness of breath. RSV is the most common cause of severe lung infections and ho...

COVID-19 Vaccine Studies

Lead Researcher: Ann Regina Falsey

URMC is studying several variations of a COVID-19 vaccine. Compensation: $500-$900. Participation Requirements: Age 18+; Have not been infected with COVID-19. To volunteer, take our survey to find out if you qualify: https://redcap.urmc.rochester.edu...

Publications

Journal Articles

Long-term efficacy and immunogenicity of Ad26.RSV.preF-RSV preF protein vaccine (CYPRESS): a randomised, double-blind, placebo-controlled, phase 2b study.

Falsey AR, Hosman T, Bastian AR, Vandenberghe S, Chan EKH, Douoguih M, Heijnen E, Comeaux CA, Callendret B,

The Lancet. Infectious diseases.. 2024 May 24 Epub 05/24/2024.

Assessment of Illness Severity in Adults Hospitalized With Acute Respiratory Tract Infection due to Influenza, Respiratory Syncytial Virus, or Human Metapneumovirus.

Falsey AR, Walsh EE, House SL, Vandendijck Y, Stevens M, Chan EKH, Ispas G

Influenza and other respiratory viruses.. 2024 May 18 (5):e13275. Epub 1900 01 01.

SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir.

Singh K, Rubenstein K, Callier V, Shaw-Saliba K, Rupert A, Dewar R, Laverdure S, Highbarger H, Lallemand P, Huang ML, Jerome KR, Sampoleo R, Mills MG, Greninger AL, Juneja K, Porter D, Benson CA, Dempsey W, El Sahly HM, Focht C, Jilg N, Paules CI, Rapaka RR, Uyeki TM, Lane HC, Beigel J, Dodd LE,

The Journal of infectious diseases.. 2024 April 24 Epub 04/24/2024.

Respiratory Syncytial Virus Prefusion F Vaccination: Antibody Persistence and Revaccination.

Walsh EE, Falsey AR, Zareba AM, Jiang Q, Gurtman A, Radley D, Gomme E, Cooper D, Jansen KU, Gruber WC, Swanson KA, Schmoele-Thoma B

The Journal of infectious diseases.. 2024 April 12 Epub 04/12/2024.

COVID-19 vaccine efficacy in participants with weakened immune systems from four randomized-controlled trials.

Sherman A, Tuan J, Cantos VD, Adeyiga O, Mahoney S, Ortega-Villa AM, Tillman A, Whitaker J, Woodward Davis AS, Leav B, Hirsch I, Sadoff J, Dunkle LM, Gilbert PB, Janes HE, Kublin JG, Goepfert PA, Kotloff K, Rouphael N, Falsey AR, El Sahly HM, Sobieszczyk ME, Huang Y, Neuzil KM, Corey L, Grinsztejn B, Gray G, Nason M, Baden LR, Gay CL

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2024 April 10 Epub 04/10/2024.

Podcast: Need for Quality Evidence for Decision-Making on Seasonal Influenza Vaccines.

Falsey AR, Maggi S, Biering-Sørensen T

Infectious diseases and therapy.. 2024 March 14 Epub 03/14/2024.

Immunomodulators for immunocompromised patients hospitalized for COVID-19: a meta-analysis of randomized controlled trials.

Siempos II, Kalil AC, Belhadi D, Veiga VC, Cavalcanti AB, Branch-Elliman W, Papoutsi E, Gkirgkiris K, Xixi NA, Kotanidou A, Hermine O, Porcher R, Mariette X, , , ,

EClinicalMedicine.. 2024 March 69 :102472. Epub 02/09/2024.

Seasonal human coronavirus humoral responses in AZD1222 (ChaAdOx1 nCoV-19) COVID-19 vaccinated adults reveal limited cross-immunity.

Stanley AM, Aksyuk AA, Wilkins D, Green JA, Lan D, Shoemaker K, Tieu HV, Sobieszczyk ME, Falsey AR, Kelly EJ

Frontiers in immunology.. 2024 15 :1401728. Epub 05/17/2024.

Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults.

Wilson E, Goswami J, Baqui AH, Doreski PA, Perez-Marc G, Zaman K, Monroy J, Duncan CJA, Ujiie M, Rämet M, Pérez-Breva L, Falsey AR, Walsh EE, Dhar R, Wilson L, Du J, Ghaswalla P, Kapoor A, Lan L, Mehta S, Mithani R, Panozzo CA, Simorellis AK, Kuter BJ, Schödel F, Huang W, Reuter C, Slobod K, Stoszek SK, Shaw CA, Miller JM, Das R, Chen GL,

The New England journal of medicine.. 2023 December 14389 (24):2233-2244. Epub 1900 01 01.

Risk of COVID-19 after natural infection or vaccination.

Rick AM, Laurens MB, Huang Y, Yu C, Martin TCS, Rodriguez CA, Rostad CA, Maboa RM, Baden LR, El Sahly HM, Grinsztejn B, Gray GE, Gay CL, Gilbert PB, Janes HE, Kublin JG, Huang Y, Leav B, Hirsch I, Struyf F, Dunkle LM, Neuzil KM, Corey L, Goepfert PA, Walsh SR, Follmann D, Kotloff KL,

EBioMedicine.. 2023 September 2096 :104799. Epub 09/20/2023.

Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial.

Branche AR, Rouphael NG, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Anderson EJ, Walter EB, Novak RM, Rupp R, Jackson LA, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Malkin E, Bethony JM, Walsh EE, Graciaa DS, Samaha H, Sherman AC, Walsh SR, Abate G, Oikonomopoulou Z, El Sahly HM, Martin TCS, Kamidani S, Smith MJ, Ladner BG, Porterfield L, Dunstan M, Wald A, Davis T, Atmar RL, Mulligan MJ, Lyke KE, Posavad CM, Meagher MA, Stephens DS, Neuzil KM, Abebe K, Hill H, Albert J, Telu K, Mu J, Lewis TC, Giebeig LA, Eaton A, Netzl A, Wilks SH, Türeli S, Makhene M, Crandon S, Montefiori DC, Makowski M, Smith DJ, Nayak SU, Roberts PC, Beigel JH,

Nature medicine.. 2023 August 28 Epub 08/28/2023.

Immunogenicity of a Two Dose Regimen of Moderna mRNA Beta/Omicron BA.1 Bivalent Variant Vaccine Boost in a Randomized Clinical Trial.

Rouphael NG, Branche AR, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, Jackson LA, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Netzl A, Smith DJ, Telu K, Mu J, McQuarrie LJ, Makowski M, Makhene MK, Crandon S, Montefiori DC, Roberts PC, Beigel JH

The Journal of infectious diseases.. 2023 August 10 Epub 08/10/2023.

Respiratory syncytial virus Prefusion F vaccine.

Falsey AR, Walsh EE

Cell.. 2023 July 20186 (15):3137-3137.e1. Epub 1900 01 01.

In-vivo and human evidence for potential efficacy of therapeutic polyclonal RSV neutralizing antibodies for palivizumab-resistant RSV infections.

Ramirez KA, Mond J, Papenburg J, Boivin G, Gilbert BE, Falsey AR, Bagga B, DeVincenzo JP

Virology.. 2023 July 18586 :115-121. Epub 07/18/2023.

Immunogenicity of NVX-CoV2373 heterologous boost against SARS-CoV-2 variants.

Lyke KE, Atmar RL, Dominguez Islas C, Posavad CM, Deming ME, Branche AR, Johnston C, El Sahly HM, Edupuganti S, Mulligan MJ, Jackson LA, Rupp RE, Rostad CA, Coler RN, Bäcker M, Kottkamp AC, Babu TM, Dobrzynski D, Martin JM, Brady RC, Frenck RW, Rajakumar K, Kotloff K, Rouphael N, Szydlo D, PaulChoudhury R, Archer JI, Crandon S, Ingersoll B, Eaton A, Brown ER, McElrath MJ, Neuzil KM, Stephens DS, Post DJ, Lin BC, Serebryannyy L, Beigel JH, Montefiori DC, Roberts PC,

NPJ vaccines.. 2023 July 118 (1):98. Epub 07/11/2023.

Clinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials.

Theodore DA, Branche AR, Zhang L, Graciaa DS, Choudhary M, Hatlen TJ, Osman R, Babu TM, Robinson ST, Gilbert PB, Follmann D, Janes H, Kublin JG, Baden LR, Goepfert P, Gray GE, Grinsztejn B, Kotloff KL, Gay CL, Leav B, Miller J, Hirsch I, Sadoff J, Dunkle LM, Neuzil KM, Corey L, Falsey AR, El Sahly HM, Sobieszczyk ME, Huang Y,

JAMA network open.. 2023 July 36 (7):e2323349. Epub 07/03/2023.

Real-Life Assessment of BioFire FilmArray® Pneumonia Panel in Adults Hospitalized with Respiratory Illness.

Falsey AR, Branche AR, Croft DP, Formica MA, Peasley MR, Walsh EE

The Journal of infectious diseases.. 2023 June 27 Epub 06/27/2023.

Modifiers of COVID-19 vaccine efficacy: Results from four COVID-19 prevention network efficacy trials.

Turley CB, Tables L, Fuller T, Sanders LJ, Scott H, Moodley A, Woodward Davis A, Leav B, Miller J, Schoemaker K, Vandebosch A, Sadoff J, Woo W, Cho I, Dunkle LM, Li S, van der Laan L, Gilbert PB, Follmann D, Jaynes H, Kublin JG, Baden LR, Goepfert P, Kotloff K, Gay CL, Falsey AR, El Sahly HM, Sobieszczyk ME, Huang Y, Neuzil KM, Corey L, Grinsztejn B, Gray G, Rouphael N, Luedtke A,

Vaccine.. 2023 June 23 Epub 06/23/2023.

Immunogenicity of a Two Dose Regimen of Moderna mRNA Beta/Omicron BA.1 Bivalent Variant Vaccine Boost in a Randomized Clinical Trial.

Rouphael NG, Branche AR, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, Jackson LA, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Netzl A, Smith DJ, Telu K, Mu J, Makowski M, Makhene MK, Crandon S, Montefiori DC, Roberts PC, Beigel JH

medRxiv : the preprint server for health sciences.. 2023 June 10 Epub 06/10/2023.

Diagnosis of Respiratory Syncytial Virus in Adults Substantially Increases When Adding Sputum, Saliva, and Serology Testing to Nasopharyngeal Swab RT-PCR.

Ramirez J, Carrico R, Wilde A, Junkins A, Furmanek S, Chandler T, Schulz P, Hubler R, Peyrani P, Liu Q, Trivedi S, Uppal S, Kalina WV, Falsey AR, Walsh EE, Yacisin K, Jodar L, Gessner BD, Begier E

Infectious diseases and therapy.. 2023 May 6 Epub 05/06/2023.

Bivalent and Monovalent SARS-CoV-2 Variant Vaccine Boosters Improve coverage of the known Antigenic Landscape: Results of the COVID-19 Variant Immunologic Landscape (COVAIL) Trial.

Branche A, Rouphael N, Diemert D, Falsey A, Losada C, Baden LR, Frey S, Whitaker J, Little S, Anderson E, Walter E, Novak R, Rupp R, Jackson L, Babu T, Kottkamp A, Luetkemeyer A, Immergluck L, Presti R, Backer M, Winokur P, Mahgoub S, Goepfert P, Fusco D, Malkin E, Bethony J, Walsh E, Graciaa D, Samaha H, Sherman A, Walsh S, Abate G, Oikonomopoulou Z, Sahly HE, Martin T, Kamidani S, Smith M, Ladner B, Porterfield L, Dunstan M, Wald A, Davis T, Atmar R, Mulligan M, Lyke K, Posavad C, Meagher M, Stephens D, Neuzil K, Abebe K, Hill H, Albert J, Telu K, Mu J, Lewis T, Giebeig L, Eaton A, Netzl A, Wilks S, Tureli S, Makhene M, Crandon S, Montefiori D, Makowski M, Smith D, Nayak S, Roberts P, Beigel J

Research square.. 2023 May 5 Epub 05/05/2023.

Immunogenicity of the BA.1 and BA.4/BA.5 SARS-CoV-2 Bivalent Boosts: Preliminary Results from the COVAIL Randomized Clinical Trial.

Branche AR, Rouphael NG, Losada C, Baden LR, Anderson EJ, Luetkemeyer AF, Diemert DJ, Winokur PL, Presti RM, Kottkamp AC, Falsey AR, Frey SE, Rupp R, Bäcker M, Novak RM, Walter EB, Jackson LA, Little SJ, Immergluck LC, Mahgoub SM, Whitaker JA, Babu TM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Netzl A, Smith DJ, Telu K, Mu J, Makowski M, Makhene MK, Crandon S, Montefiori DC, Roberts PC, Beigel JH

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2023 April 10 Epub 04/10/2023.

Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults.

Walsh EE, Pérez Marc G, Zareba AM, Falsey AR, Jiang Q, Patton M, Polack FP, Llapur C, Doreski PA, Ilangovan K, Rämet M, Fukushima Y, Hussen N, Bont LJ, Cardona J, DeHaan E, Castillo Villa G, Ingilizova M, Eiras D, Mikati T, Shah RN, Schneider K, Cooper D, Koury K, Lino MM, Anderson AS, Jansen KU, Swanson KA, Gurtman A, Gruber WC, Schmoele-Thoma B,

The New England journal of medicine.. 2023 April 5 Epub 04/05/2023.

Immunogenicity of the BA.1 and BA.4/BA.5 SARS-CoV-2 Bivalent Boosts: Preliminary Results from the COVAIL Randomized Clinical Trial.

Branche AR, Rouphael NG, Losada C, Baden LR, Anderson EJ, Luetkemeyer AF, Diemert DJ, Winokur PL, Presti RM, Kottkamp AC, Falsey AR, Frey SE, Rupp R, Bäcker M, Novak RM, Walter EB, Jackson LA, Little SJ, Immergluck LC, Mahgoub SM, Whitaker JA, Babu TM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Netzl A, Smith DJ, Telu K, Mu J, Makowski M, Makhene MK, Crandon S, Montefiori DC, Roberts PC, Beigel JH

medRxiv : the preprint server for health sciences.. 2023 March 31 Epub 03/31/2023.

Immune correlates analysis of a phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine.

Benkeser D, Fong Y, Janes HE, Kelly EJ, Hirsch I, Sproule S, Stanley AM, Maaske J, Villafana T, Houchens CR, Martins K, Jayashankar L, Castellino F, Ayala V, Petropoulos CJ, Leith A, Haugaard D, Webb B, Lu Y, Yu C, Borate B, van der Laan LWP, Hejazi NS, Carpp LN, Randhawa AK, Andrasik MP, Kublin JG, Isaacs MB, Makhene M, Tong T, Robb ML, Corey L, Neuzil KM, Follmann D, Hoffman C, Falsey AR, Sobieszczyk M, Koup RA, Donis RO, Gilbert PB, , ,

NPJ vaccines.. 2023 March 118 (1):36. Epub 03/11/2023.

Efficacy and Safety of an Ad26.RSV.preF-RSV preF Protein Vaccine in Older Adults.

Falsey AR, Williams K, Gymnopoulou E, Bart S, Ervin J, Bastian AR, Menten J, De Paepe E, Vandenberghe S, Chan EKH, Sadoff J, Douoguih M, Callendret B, Comeaux CA, Heijnen E,

The New England journal of medicine.. 2023 February 16388 (7):609-620. Epub 1900 01 01.

Rapid Development of an Integrated Network Infrastructure to Conduct Phase 3 COVID-19 Vaccine Trials.

Mena Lora AJ, Long JE, Huang Y, Baden LR, El Sahly HM, Follmann D, Goepfert P, Gray G, Grinsztejn B, Kotloff K, Rouphael N, Sobieszczyk M, Walsh SR, Andriesen J, Shah KA, Zhang Y, Gilbert P, Janes H, Gay CL, Falsey AR, Tripp RL, Gorman RL, Tong T, Marovich M, Neuzil K, Corey L, Kublin JG,

JAMA network open.. 2023 January 36 (1):e2251974. Epub 01/03/2023.

AZD1222-induced nasal antibody responses are shaped by prior SARS-CoV-2 infection and correlate with virologic outcomes in breakthrough infection.

Aksyuk AA, Bansal H, Wilkins D, Stanley AM, Sproule S, Maaske J, Sanikommui S, Hartman WR, Sobieszczyk ME, Falsey AR, Kelly EJ

Cell reports. Medicine.. 2022 December 15 :100882. Epub 12/15/2022.

Clinical impact of healthcare-associated respiratory syncytial virus in hospitalized adults.

Hill-Ricciuti A, Walsh EE, Greendyke WG, Choi Y, Barrett A, Alba L, Branche AR, Falsey AR, Phillips M, Finelli L, Saiman L

Infection control and hospital epidemiology.. 2022 November 14 :1-7. Epub 11/14/2022.

Perturbations in Respiratory Syncytial Virus (RSV) Activity During the SARS-CoV-2 Pandemic.

Falsey AR, Cameron A, Branche AR, Walsh EE

The Journal of infectious diseases.. 2022 November 1 Epub 11/01/2022.

Use of Host Response to Refine the Diagnosis of Group A Streptococcal Pharyngitis.

Yu J, Tycksen E, Yang W, Mariani TJ, Bhattacharya S, Falsey AR, Topham DJ, Storch GA

Journal of the Pediatric Infectious Diseases Society.. 2022 September 25 Epub 09/25/2022.

Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months.

Sobieszczyk ME, Maaske J, Falsey AR, Sproule S, Robb ML, Frenck RW, Tieu HV, Mayer KH, Corey L, Neuzil KM, Tong T, Brewinski Isaacs M, Janes H, Bansal H, Edwards LM, Green JA, Kelly EJ, Shoemaker K, Takas T, White T, Bhuyan P, Villafana T, Hirsch AI,

The Journal of clinical investigation.. 2022 September 15132 (18)Epub 09/15/2022.

Change in functional status associated with respiratory syncytial virus infection in hospitalized older adults.

Branche AR, Saiman L, Walsh EE, Falsey AR, Jia H, Barrett A, Alba L, Phillips M, Finelli L

Influenza and other respiratory viruses.. 2022 September 7 Epub 09/07/2022.

SARS-CoV-2 Variant Vaccine Boosters Trial: Preliminary Analyses.

Branche AR, Rouphael NG, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Anderson EJ, Walter EB, Novak RM, Rupp R, Jackson LA, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Malkin E, Bethony JM, Walsh EE, Graciaa DS, Samaha H, Sherman AC, Walsh SR, Abate G, Oikonomopoulou Z, El Sahly HM, Martin TCS, Rostad CA, Smith MJ, Ladner BG, Porterfield L, Dunstan M, Wald A, Davis T, Atmar RL, Mulligan MJ, Lyke KE, Posavad CM, Meagher MA, Stephens DS, Neuzil KM, Abebe K, Hill H, Albert J, Lewis TC, Giebeig LA, Eaton A, Netzl A, Wilks SH, Türeli S, Makhene M, Crandon S, Lee M, Nayak SU, Montefiori DC, Makowski M, Smith DJ, Roberts PC, Beigel JH,

medRxiv : the preprint server for health sciences.. 2022 July 15 Epub 07/15/2022.

Rates of Medically Attended RSV Among US Adults: A Systematic Review and Meta-analysis.

McLaughlin JM, Khan F, Begier E, Swerdlow DL, Jodar L, Falsey AR

Open forum infectious diseases.. 2022 July 9 (7):ofac300. Epub 06/17/2022.

Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant.

Lyke KE, Atmar RL, Islas CD, Posavad CM, Szydlo D, Paul Chourdhury R, Deming ME, Eaton A, Jackson LA, Branche AR, El Sahly HM, Rostad CA, Martin JM, Johnston C, Rupp RE, Mulligan MJ, Brady RC, Frenck RW, Bäcker M, Kottkamp AC, Babu TM, Rajakumar K, Edupuganti S, Dobrzynski D, Coler RN, Archer JI, Crandon S, Zemanek JA, Brown ER, Neuzil KM, Stephens DS, Post DJ, Nayak SU, Suthar MS, Roberts PC, Beigel JH, Montefiori DC,

Cell reports. Medicine.. 2022 June 20 :100679. Epub 06/20/2022.

Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial.

Wolfe CR, Tomashek KM, Patterson TF, Gomez CA, Marconi VC, Jain MK, Yang OO, Paules CI, Palacios GMR, Grossberg R, Harkins MS, Mularski RA, Erdmann N, Sandkovsky U, Almasri E, Pineda JR, Dretler AW, de Castilla DL, Branche AR, Park PK, Mehta AK, Short WR, McLellan SLF, Kline S, Iovine NM, El Sahly HM, Doernberg SB, Oh MD, Huprikar N, Hohmann E, Kelley CF, Holodniy M, Kim ES, Sweeney DA, Finberg RW, Grimes KA, Maves RC, Ko ER, Engemann JJ, Taylor BS, Ponce PO, Larson L, Melendez DP, Seibert AM, Rouphael NG, Strebe J, Clark JL, Julian KG, de Leon AP, Cardoso A, de Bono S, Atmar RL, Ganesan A, Ferreira JL, Green M, Makowski M, Bonnett T, Beresnev T, Ghazaryan V, Dempsey W, Nayak SU, Dodd LE, Beigel JH, Kalil AC,

The Lancet. Respiratory medicine.. 2022 May 23 Epub 05/23/2022.

Serum levels of anti-PF4 IgG after AZD1222 (ChAdOx1 nCoV-19) vaccination.

Cohen TS, Kelly EJ, Nylander S, Bansal H, Jepson BM, Bhuyan P, Sobieszczyk ME, Falsey AR

Scientific reports.. 2022 May 1312 (1):7961. Epub 05/13/2022.

Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy.

McDavid A, Laniewski N, Grier A, Gill AL, Kessler HA, Huyck H, Carbonell E, Holden-Wiltse J, Bandyopadhyay S, Carnahan J, Dylag AM, Topham DJ, Falsey AR, Caserta MT, Pryhuber GS, Gill SR, Scheible KM

iScience.. 2022 April 1525 (4):104007. Epub 03/01/2022.

A Systematic Review of European Clinical Practice Guidelines for Respiratory Syncytial Virus Prophylaxis.

Reeves RM, van Wijhe M, Lehtonen T, Stona L, Teirlinck AC, Vazquez Fernandez L, Li Y, Osei-Yeboah R, Fischer TK, Heikkinen T, van Boven M, Bøås H, Donà D, Barbieri E, Campbell H,

The Journal of infectious diseases.. 2022 March 25 Epub 03/25/2022.

Homologous and Heterologous Covid-19 Booster Vaccinations.

Atmar RL, Lyke KE, Deming ME, Jackson LA, Branche AR, El Sahly HM, Rostad CA, Martin JM, Johnston C, Rupp RE, Mulligan MJ, Brady RC, Frenck RW, Bäcker M, Kottkamp AC, Babu TM, Rajakumar K, Edupuganti S, Dobrzynski D, Coler RN, Posavad CM, Archer JI, Crandon S, Nayak SU, Szydlo D, Zemanek JA, Dominguez Islas CP, Brown ER, Suthar MS, McElrath MJ, McDermott AB, O'Connell SE, Montefiori DC, Eaton A, Neuzil KM, Stephens DS, Roberts PC, Beigel JH,

The New England journal of medicine.. 2022 January 26 Epub 01/26/2022.

Featured Cover.

Falsey AR, Walsh EE, Osborne RH, Vandendijck Y, Ren X, Witek J, Kang D, Chan E, Scott J, Ispas G

Influenza and other respiratory viruses.. 2022 January 16 (1):i. Epub 12/21/2021.

Robust humoral and cellular recall responses to AZD1222 attenuate breakthrough SARS-CoV-2 infection compared to unvaccinated.

Maaske J, Sproule S, Falsey AR, Sobieszczyk ME, Luetkemeyer AF, Paulsen GC, Riddler SA, Robb ML, Rolle CP, Sha BE, Tong T, Ahani B, Aksyuk AA, Bansal H, Egan T, Jepson B, Padilla M, Patel N, Shoemaker K, Stanley AM, Swanson PA, Wilkins D, Villafana T, Green JA, Kelly EJ

Frontiers in immunology.. 2022 13 :1062067. Epub 01/13/2023.

A systems genomics approach uncovers molecular associates of RSV severity.

McCall MN, Chu CY, Wang L, Benoodt L, Thakar J, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Qiu X, Mariani TJ

PLoS computational biology.. 2021 December 2817 (12):e1009617. Epub 12/28/2021.

Phase 1/2 Randomized Study of the Immunogenicity, Safety and Tolerability of an RSV Prefusion F Vaccine in Adults With Concomitant Inactivated Influenza Vaccine.

Falsey AR, Walsh EE, Scott DA, Gurtman A, Zareba A, Jansen KU, Gruber WC, Dormitzer PR, Swanson KA, Jiang Q, Gomme E, Cooper D, Schmoele-Thoma B,

The Journal of infectious diseases.. 2021 December 21 Epub 12/21/2021.

A Randomized Phase 1/2 Study of a Respiratory Syncytial Virus Prefusion F Vaccine.

Walsh EE, Falsey AR, Scott DA, Gurtman A, Zareba AM, Jansen KU, Gruber WC, Dormitzer PR, Swanson KA, Radley D, Gomme E, Cooper D, Schmoele-Thoma B,

The Journal of infectious diseases.. 2021 December 21 Epub 12/21/2021.

World Health Organization Influenza-Like Illness Underestimates the Burden of Respiratory Syncytial Virus Infection in Community-Dwelling Older Adults.

Korsten K, Adriaenssens N, Coenen S, Butler CC, Verheij TJM, Bont LJ, Wildenbeest JG,

The Journal of infectious diseases.. 2021 December 14 Epub 12/14/2021.

Gene Expression Risk Scores for COVID-19 Illness Severity.

Peterson DR, Baran AM, Bhattacharya S, Branche AR, Croft DP, Corbett AM, Walsh EE, Falsey AR, Mariani TJ

The Journal of infectious diseases.. 2021 November 30 Epub 11/30/2021.

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months.

Thomas SJ, Moreira ED, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez JL, Pérez Marc G, Polack FP, Zerbini C, Bailey R, Swanson KA, Xu X, Roychoudhury S, Koury K, Bouguermouh S, Kalina WV, Cooper D, Frenck RW, Hammitt LL, Türeci Ö, Nell H, Schaefer A, Ünal S, Yang Q, Liberator P, Tresnan DB, Mather S, Dormitzer PR, ?ahin U, Gruber WC, Jansen KU,

The New England journal of medicine.. 2021 November 4385 (19):1761-1773. Epub 09/15/2021.

Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial.

Kalil AC, Mehta AK, Patterson TF, Erdmann N, Gomez CA, Jain MK, Wolfe CR, Ruiz-Palacios GM, Kline S, Regalado Pineda J, Luetkemeyer AF, Harkins MS, Jackson PEH, Iovine NM, Tapson VF, Oh MD, Whitaker JA, Mularski RA, Paules CI, Ince D, Takasaki J, Sweeney DA, Sandkovsky U, Wyles DL, Hohmann E, Grimes KA, Grossberg R, Laguio-Vila M, Lambert AA, Lopez de Castilla D, Kim E, Larson L, Wan CR, Traenkner JJ, Ponce PO, Patterson JE, Goepfert PA, Sofarelli TA, Mocherla S, Ko ER, Ponce de Leon A, Doernberg SB, Atmar RL, Maves RC, Dangond F, Ferreira J, Green M, Makowski M, Bonnett T, Beresnev T, Ghazaryan V, Dempsey W, Nayak SU, Dodd L, Tomashek KM, Beigel JH,

The Lancet. Respiratory medicine.. 2021 October 18 Epub 10/18/2021.

Cost determinants among adults hospitalized with respiratory syncytial virus in the United States, 2017-2019.

Choi Y, Hill-Ricciuti A, Branche AR, Sieling WD, Saiman L, Walsh EE, Phillips M, Falsey AR, Finelli L

Influenza and other respiratory viruses.. 2021 October 3 Epub 10/03/2021.

The effect of air pollution on the transcriptomics of the immune response to respiratory infection.

Croft DP, Burton DS, Nagel DJ, Bhattacharya S, Falsey AR, Georas SN, Hopke PK, Johnston CJ, Kottmann RM, Litonjua AA, Mariani TJ, Rich DQ, Thevenet-Morrison K, Thurston SW, Utell MJ, McCall MN

Scientific reports.. 2021 September 3011 (1):19436. Epub 09/30/2021.

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine.

Falsey AR, Sobieszczyk ME, Hirsch I, Sproule S, Robb ML, Corey L, Neuzil KM, Hahn W, Hunt J, Mulligan MJ, McEvoy C, DeJesus E, Hassman M, Little SJ, Pahud BA, Durbin A, Pickrell P, Daar ES, Bush L, Solis J, Carr QO, Oyedele T, Buchbinder S, Cowden J, Vargas SL, Benavides AG, Call R, Keefer MC, Kirkpatrick BD, Pullman J, Tong T, Isaacs MB, Benkeser D, Janes HE, Nason MC, Green JA, Kelly EJ, Maaske J, Mueller N, Shoemaker K, Takas T, Marshall RP, Pangalos MN, Villafana T, Gonzalez-Lopez A,

The New England journal of medicine.. 2021 September 29 Epub 09/29/2021.

Disease Burden Estimates of Respiratory Syncytial Virus related Acute Respiratory Infections in Adults With Comorbidity: A Systematic Review and Meta-Analysis.

Shi T, Vennard S, Jasiewicz F, Brogden R, Nair H,

The Journal of infectious diseases.. 2021 September 15 Epub 09/15/2021.

SARS-CoV-2 Neutralization with BNT162b2 Vaccine Dose 3.

Falsey AR, Frenck RW, Walsh EE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Bailey R, Swanson KA, Xu X, Koury K, Kalina W, Cooper D, Zou J, Xie X, Xia H, Türeci Ö, Lagkadinou E, Tompkins KR, Shi PY, Jansen KU, ?ahin U, Dormitzer PR, Gruber WC

The New England journal of medicine.. 2021 September 15 Epub 09/15/2021.

Comparative assessment of reported symptoms of influenza, respiratory syncytial virus, and human metapneumovirus infection during hospitalization and post-discharge assessed by Respiratory Intensity and Impact Questionnaire.

Falsey AR, Walsh EE, Osborne RH, Vandendijck Y, Ren X, Witek J, Kang D, Chan E, Scott J, Ispas G

Influenza and other respiratory viruses.. 2021 September 2 Epub 09/02/2021.

Gene Expression Risk Scores for COVID-19 Illness Severity.

Peterson DR, Baran AM, Bhattacharya S, Branche AR, Croft DP, Corbett AM, Walsh EE, Falsey AR, Mariani TJ

bioRxiv : the preprint server for biology.. 2021 August 24 Epub 08/24/2021.

Incidence of Respiratory Syncytial Virus Infection among Hospitalized Adults, 2017-2020.

Branche AR, Saiman L, Walsh EE, Falsey AR, Sieling WD, Greendyke W, Peterson DR, Vargas CY, Phillips M, Finelli L

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2021 July 9 Epub 07/09/2021.

A Glimmer of Hope for the Most Vulnerable.

Falsey AR

Journal of the American Geriatrics Society.. 2021 April 19 Epub 04/19/2021.

Airway gene-expression classifiers for respiratory syncytial virus (RSV) disease severity in infants.

Wang L, Chu CY, McCall MN, Slaunwhite C, Holden-Wiltse J, Corbett A, Falsey AR, Topham DJ, Caserta MT, Mariani TJ, Walsh EE, Qiu X

BMC medical genomics.. 2021 February 2514 (1):57. Epub 02/25/2021.

Publisher Correction: Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults.

Mulligan MJ, Lyke KE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Raabe V, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Walsh EE, Frenck R, Falsey AR, Dormitzer PR, Gruber WC, ?ahin U, Jansen KU

Nature.. 2021 January 19 Epub 01/19/2021.

Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells.

Kyu S, Ramonell RP, Kuruvilla M, Kraft CS, Wang YF, Falsey AR, Walsh EE, Daiss JL, Paulos S, Rajam G, Wu H, Velusamy S, Lee FE

PloS one.. 2021 16 (11):e0259644. Epub 11/12/2021.

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.

Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez JL, Pérez Marc G, Moreira ED, Zerbini C, Bailey R, Swanson KA, Roychoudhury S, Koury K, Li P, Kalina WV, Cooper D, Frenck RW, Hammitt LL, Türeci Ö, Nell H, Schaefer A, Ünal S, Tresnan DB, Mather S, Dormitzer PR, ?ahin U, Jansen KU, Gruber WC,

The New England journal of medicine.. 2020 December 31383 (27):2603-2615. Epub 12/10/2020.

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.

Kalil AC, Patterson TF, Mehta AK, Tomashek KM, Wolfe CR, Ghazaryan V, Marconi VC, Ruiz-Palacios GM, Hsieh L, Kline S, Tapson V, Iovine NM, Jain MK, Sweeney DA, El Sahly HM, Branche AR, Regalado Pineda J, Lye DC, Sandkovsky U, Luetkemeyer AF, Cohen SH, Finberg RW, Jackson PEH, Taiwo B, Paules CI, Arguinchona H, Goepfert P, Ahuja N, Frank M, Oh MD, Kim ES, Tan SY, Mularski RA, Nielsen H, Ponce PO, Taylor BS, Larson L, Rouphael NG, Saklawi Y, Cantos VD, Ko ER, Engemann JJ, Amin AN, Watanabe M, Billings J, Elie MC, Davey RT, Burgess TH, Ferreira J, Green M, Makowski M, Cardoso A, de Bono S, Bonnett T, Proschan M, Deye GA, Dempsey W, Nayak SU, Dodd LE, Beigel JH

The New England journal of medicine.. 2020 December 11 Epub 12/11/2020.

Burden of respiratory syncytial virus infection in community-dwelling older adults in Europe (RESCEU): an international prospective cohort study.

Korsten K, Adriaenssens N, Coenen S, Butler C, Ravanfar B, Rutter H, Allen J, Falsey A, Pirçon JY, Gruselle O, Pavot V, Vernhes C, Balla-Jhagjhoorsingh S, Öner D, Ispas G, Aerssens J, Shinde V, Verheij T, Bont L, Wildenbeest J,

The European respiratory journal.. 2020 October 15 Epub 10/15/2020.

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates.

Walsh EE, Frenck RW, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Lyke KE, Raabe V, Dormitzer PR, Jansen KU, ?ahin U, Gruber WC

The New England journal of medicine.. 2020 October 14 Epub 10/14/2020.

Remdesivir for the Treatment of Covid-19 - Final Report.

Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, Hohmann E, Chu HY, Luetkemeyer A, Kline S, Lopez de Castilla D, Finberg RW, Dierberg K, Tapson V, Hsieh L, Patterson TF, Paredes R, Sweeney DA, Short WR, Touloumi G, Lye DC, Ohmagari N, Oh MD, Ruiz-Palacios GM, Benfield T, Fätkenheuer G, Kortepeter MG, Atmar RL, Creech CB, Lundgren J, Babiker AG, Pett S, Neaton JD, Burgess TH, Bonnett T, Green M, Makowski M, Osinusi A, Nayak S, Lane HC

The New England journal of medicine.. 2020 October 8 Epub 10/08/2020.

Acute Lower Respiratory Infections Associated With Respiratory Syncytial Virus in Children With Underlying Congenital Heart Disease: Systematic Review and Meta-analysis.

Chaw PS, Wong SWL, Cunningham S, Campbell H, Mikolajczyk R, Nair H,

The Journal of infectious diseases.. 2020 October 7222 (Supplement_7):S613-S619. Epub 1900 01 01.

Temporal Dysbiosis of Infant Nasal Microbiota Relative to Respiratory Syncytial Virus Infection.

Grier A, Gill AL, Kessler HA, Corbett A, Bandyopadhyay S, Java J, Holden-Wiltse J, Falsey AR, Topham DJ, Mariani TJ, Caserta MT, Walsh EE, Gill SR

The Journal of infectious diseases.. 2020 September 14 Epub 09/14/2020.

Airway gene expression correlates of RSV disease severity and microbiome composition in infants.

Chu CY, Qiu X, McCall MN, Wang L, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Pryhuber GS, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Mariani TJ

The Journal of infectious diseases.. 2020 September 14 Epub 09/14/2020.

RNA-Based COVID-19 Vaccine BNT162b2 Selected for a Pivotal Efficacy Study.

Walsh EE, Frenck R, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Thompkins KR, Lyke KE, Raabe V, Dormitzer PR, Jansen KU, Sahin U, Gruber WC

medRxiv : the preprint server for health sciences.. 2020 August 20 Epub 08/20/2020.

The impact of influenza vaccination on the COVID-19 pandemic? Evidence and lessons for public health policies.

Paget J, Caini S, Cowling B, Esposito S, Falsey AR, Gentile A, Kyncl J, McIntyre C, Pitman R, Lina B

Vaccine.. 2020 August 19 Epub 08/19/2020.

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults.

Mulligan MJ, Lyke KE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Raabe V, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Walsh EE, Frenck R, Falsey AR, Dormitzer PR, Gruber WC, ?ahin U, Jansen KU

Nature.. 2020 August 12 Epub 08/12/2020.

Unbiased analysis of peripheral blood mononuclear cells reveals CD4 T cell response to RSV matrix protein.

Thakar J, Qian Y, Benoodt L, Roumanes D, Qiu X, Laniewski N, Chu C, Slaunwhite C, Wang L, Mandava A, Chang I, Falsey AR, Caserta MT, Mariani TJ, Scheuermann RH, Walsh EE, Topham DJ

Vaccine: X.. 2020 August 75 :100065. Epub 04/21/2020.

Syncope, Near Syncope, or Nonmechanical Falls as a Presenting Feature of COVID-19.

Chen T, Hanna J, Walsh EE, Falsey AR, Laguio-Vila M, Lesho E

Annals of emergency medicine.. 2020 July 76 (1):115-117. Epub 05/08/2020.

Respiratory Syncytial Virus: An Old Foe in a New Era.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 2020 June 27 Epub 06/27/2020.

Evaluation of the protective potential of antibody and T cell responses elicited by a novel preventative vaccine towards respiratory syncytial virus small hydrophobic protein.

Torrey HL, Kaliaperumal V, Bramhecha Y, Weir GM, Falsey AR, Walsh EE, Langley JM, Schepens B, Saelens X, Stanford MM

Human vaccines & immunotherapeutics.. 2020 June 12 :1-11. Epub 06/12/2020.

Immunological and Inflammatory Biomarkers of Susceptibility and Severity in Adult Respiratory Syncytial Virus Infections.

Wiseman DJ, Thwaites RS, Drysdale SB, Janet S, Donaldson GC, Wedzicha JA, Openshaw PJ,

The Journal of infectious diseases.. 2020 March 30 Epub 03/30/2020.

More is better: influenza vaccines in patients with rheumatoid arthritis.

Falsey AR

The Lancet. Rheumatology.. 2020 January 2 (1):e2-e3. Epub 11/20/2019.

Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infections in Children With Bronchopulmonary Dysplasia: Systematic Review and Meta-Analysis.

Chaw PS, Hua L, Cunningham S, Campbell H, Mikolajczyk R, Nair H,

The Journal of infectious diseases.. 2019 December 11 Epub 12/11/2019.

Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus Infection.

Sonawane AR, Tian L, Chu CY, Qiu X, Wang L, Holden-Wiltse J, Grier A, Gill SR, Caserta MT, Falsey AR, Topham DJ, Walsh EE, Mariani TJ, Weiss ST, Silverman EK, Glass K, Liu YY

Scientific reports.. 2019 September 259 (1):13824. Epub 09/25/2019.

Association Between Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infection in Early Life and Recurrent Wheeze and Asthma in Later Childhood.

Shi T, Ooi Y, Zaw EM, Utjesanovic N, Campbell H, Cunningham S, Bont L, Nair H,

The Journal of infectious diseases.. 2019 August 1 Epub 08/01/2019.

Measuring the Severity of Respiratory Illness in the First 2 Years of Life in Preterm and Term Infants.

Caserta MT, Yang H, Bandyopadhyay S, Qiu X, Gill SR, Java J, McDavid A, Falsey AR, Topham DJ, Holden-Wiltse J, Scheible K, Pryhuber G

The Journal of pediatrics.. 2019 July 31 Epub 07/31/2019.

Viral pathogens associated with acute respiratory illness in hospitalized adults and elderly from Zagreb, Croatia, 2016 to 2018.

Civljak R, Tot T, Falsey AR, Huljev E, Vranes J, Ljubin-Sternak S

Journal of medical virology.. 2019 July 91 (7):1202-1209. Epub 03/04/2019.

Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study.

Walsh EE, Mariani TJ, Chu C, Grier A, Gill SR, Qiu X, Wang L, Holden-Wiltse J, Corbett A, Thakar J, Benoodt L, McCall MN, Topham DJ, Falsey AR, Caserta MT

JMIR research protocols.. 2019 June 68 (6):e12907. Epub 06/06/2019.

What is the role of rapid molecular testing for seniors and other at-risk adults with respiratory syncytial virus infections?

Drews SJ, Branche AR, Falsey AR, Lee N

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2019 May 25117 :27-32. Epub 05/25/2019.

Highly efficient hypothesis testing methods for regression-type tests with correlated observations and heterogeneous variance structure.

Zhang Y, Bandyopadhyay G, Topham DJ, Falsey AR, Qiu X

BMC bioinformatics.. 2019 April 1520 (1):185. Epub 04/15/2019.

Host Gene Expression in Nose and Blood for the Diagnosis of Viral Respiratory Infection.

Yu J, Peterson DR, Baran AM, Bhattacharya S, Wylie TN, Falsey AR, Mariani TJ, Storch GA

The Journal of infectious diseases.. 2019 April 1219 (7):1151-1161. Epub 1900 01 01.

Global Disease Burden Estimates of Respiratory Syncytial Virus-Associated Acute Respiratory Infection in Older Adults in 2015: A Systematic Review and Meta-Analysis.

Shi T, Denouel A, Tietjen AK, Campbell I, Moran E, Li X, Campbell H, Demont C, Nyawanda BO, Chu HY, Stoszek SK, Krishnan A, Openshaw P, Falsey AR, Nair H,

The Journal of infectious diseases.. 2019 March 18 Epub 03/18/2019.

Global and Regional Burden of Hospital Admissions for Pneumonia in Older Adults: A Systematic Review and Meta-Analysis.

Shi T, Denouel A, Tietjen AK, Lee JW, Falsey AR, Demont C, Nyawanda BO, Cai B, Fuentes R, Stoszek SK, Openshaw P, Campbell H, Nair H,

The Journal of infectious diseases.. 2019 March 8 Epub 03/08/2019.

The Etiological Role of Common Respiratory Viruses in Acute Respiratory Infections in Older Adults: A Systematic Review and Meta-analysis.

Shi T, Arnott A, Semogas I, Falsey AR, Openshaw P, Wedzicha JA, Campbell H, Nair H,

The Journal of infectious diseases.. 2019 March 8 Epub 03/08/2019.

Respiratory syncytial virus-associated illness in adults with advanced chronic obstructive pulmonary disease and/or congestive heart failure.

Falsey AR, Walsh EE, Esser MT, Shoemaker K, Yu L, Griffin MP

Journal of medical virology.. 2019 January 91 (1):65-71. Epub 09/24/2018.

Procalcitonin in patients with fever: one approach does not fit all.

Schuetz P, Falsey AR

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.. 2018 December 24 (12):1229-1230. Epub 08/01/2018.

Neonatal gut and respiratory microbiota: coordinated development through time and space.

Grier A, McDavid A, Wang B, Qiu X, Java J, Bandyopadhyay S, Yang H, Holden-Wiltse J, Kessler HA, Gill AL, Huyck H, Falsey AR, Topham DJ, Scheible KM, Caserta MT, Pryhuber GS, Gill SR

Microbiome.. 2018 October 266 (1):193. Epub 10/26/2018.

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ,

The Lancet. Infectious diseases.. 2018 October 18 (10):e295-e311. Epub 06/18/2018.

Improving ability of RSV microneutralization assay to detect G-specific and cross-reactive neutralizing antibodies through immortalized cell line selection.

Boukhvalova MS, Mbaye A, Kovtun S, Yim KC, Konstantinova T, Getachew T, Khurana S, Falsey AR, Blanco JCG

Vaccine.. 2018 July 2536 (31):4657-4662. Epub 06/28/2018.

Effect of prior vaccination on carriage rates of Streptococcus pneumoniae in older adults: A longitudinal surveillance study.

Branche AR, Yang H, Java J, Wiltse-Holden J, Topham DJ, Peasley M, Frost MR, Nahm MH, Falsey AR

Vaccine.. 2018 July 536 (29):4304-4310. Epub 06/02/2018.

T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection.

Roumanes D, Falsey AR, Quataert S, Secor-Socha S, Lee FE, Yang H, Bandyopadhyay S, Holden-Wiltse J, Topham DJ, Walsh EE

The Journal of infectious diseases.. 2018 July 2218 (3):418-428. Epub 1900 01 01.

Virus-Specific Antibody, Viral Load, and Disease Severity in Respiratory Syncytial Virus Infection.

Walsh EE, Wang L, Falsey AR, Qiu X, Corbett A, Holden-Wiltse J, Mariani TJ, Topham DJ, Caserta MT

The Journal of infectious diseases.. 2018 June 20218 (2):208-217. Epub 1900 01 01.

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis.

Schuetz P, Wirz Y, Sager R, Christ-Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, Chastre J, Tubach F, Kristoffersen KB, Burkhardt O, Welte T, Schroeder S, Nobre V, Wei L, Bucher HC, Annane D, Reinhart K, Falsey AR, Branche A, Damas P, Nijsten M, de Lange DW, Deliberato RO, Oliveira CF, Maravi?-Stojkovi? V, Verduri A, Beghé B, Cao B, Shehabi Y, Jensen JS, Corti C, van Oers JAH, Beishuizen A, Girbes ARJ, de Jong E, Briel M, Mueller B

The Lancet. Infectious diseases.. 2018 January 18 (1):95-107. Epub 10/13/2017.

Influenza burden in frail elderly.

Falsey AR, McElhaney JE

The Lancet. Respiratory medicine.. 2018 January 6 (1):e2. Epub 1900 01 01.

An Adjuvanted, Postfusion F Protein-Based Vaccine Did Not Prevent Respiratory Syncytial Virus Illness in Older Adults.

Falloon J, Yu J, Esser MT, Villafana T, Yu L, Dubovsky F, Takas T, Levin MJ, Falsey AR

The Journal of infectious diseases.. 2017 December 12216 (11):1362-1370. Epub 1900 01 01.

Management of Respiratory Infections with Use of Procalcitonin: Moving toward More Personalized Antibiotic Treatment Decisions.

Wirz Y, Branche A, Wolff M, Welte T, Nobre V, Reinhart K, Falsey AR, Damas P, Beishuizen A, Deliberato RO, Shehabi Y, Jensen JS, Mueller B, Schuetz P

ACS infectious diseases.. 2017 December 83 (12):875-879. Epub 11/09/2017.

Viral Diagnostics: Only Half the Battle.

Branche AR, Falsey AR

The Journal of infectious diseases.. 2017 November 15216 (8):923-925. Epub 1900 01 01.

Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young Infants.

Mariani TJ, Qiu X, Chu CY, Wang L, Thakar J, Holden-Wiltse J, Corbett A, Topham DJ, Falsey AR, Caserta MT, Walsh EE

The Journal of infectious diseases.. 2017 November 15216 (8):1027-1037. Epub 1900 01 01.

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.

Schuetz P, Wirz Y, Sager R, Christ-Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, Chastre J, Tubach F, Kristoffersen KB, Burkhardt O, Welte T, Schroeder S, Nobre V, Wei L, Bucher HC, Bhatnagar N, Annane D, Reinhart K, Branche A, Damas P, Nijsten M, de Lange DW, Deliberato RO, Lima SS, Maravi?-Stojkovi? V, Verduri A, Cao B, Shehabi Y, Beishuizen A, Jensen JS, Corti C, Van Oers JA, Falsey AR, de Jong E, Oliveira CF, Beghe B, Briel M, Mueller B

The Cochrane database of systematic reviews.. 2017 October 1210 (10):CD007498. Epub 10/12/2017.

Identifying Gaps in Respiratory Syncytial Virus Disease Epidemiology in the United States Prior to the Introduction of Vaccines.

Kim L, Rha B, Abramson JS, Anderson LJ, Byington CL, Chen GL, DeVincenzo J, Edwards KM, Englund JA, Falsey AR, Griffin MR, Karron RA, Martin KG, Meissner HC, Munoz FM, Pavia AT, Piedra PA, Schaffner W, Simões EAF, Singleton R, Talbot HK, Walsh EE, Zucker JR, Gerber SI

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2017 September 1565 (6):1020-1025. Epub 1900 01 01.

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.

Bhattacharya S, Rosenberg AF, Peterson DR, Grzesik K, Baran AM, Ashton JM, Gill SR, Corbett AM, Holden-Wiltse J, Topham DJ, Walsh EE, Mariani TJ, Falsey AR

Scientific reports.. 2017 July 267 (1):6548. Epub 07/26/2017.

Can Analysis of Routine Viral Testing Provide Accurate Estimates of Respiratory Syncytial Virus Disease Burden in Adults?

Datta S, Walsh EE, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2017 June 1215 (11):1706-1710. Epub 1900 01 01.

Compassionate use experience with high-titer respiratory syncytical virus (RSV) immunoglobulin in RSV-infected immunocompromised persons.

Falsey AR, Koval C, DeVincenzo JP, Walsh EE

Transplant infectious disease : an official journal of the Transplantation Society.. 2017 April 19 (2)Epub 03/06/2017.

Development of a Global Respiratory Severity Score for Respiratory Syncytial Virus Infection in Infants.

Caserta MT, Qiu X, Tesini B, Wang L, Murphy A, Corbett A, Falsey AR, Holden-Wiltse J, Walsh EE

The Journal of infectious diseases.. 2017 March 1215 (5):750-756. Epub 1900 01 01.

Acute Disseminated Histoplasmosis with Atypical Lymphocytosis in an Immunocompetent Host.

Elbadawi A, Ahmed HM, Adly H, Elkhouly MA, Abohamed S, Falsey AR

IDCases.. 2017 7 :23-24. Epub 11/25/2016.

s Endocarditis with an unstable phenotype: the challenges of isolate characterization and Carbapenem stewardship with a partial review of the literature.

Lesho E, Snesrud E, Kwak Y, Ong A, Maybank R, Laguio-Vila M, Falsey AR, Hinkle M

Antimicrobial resistance and infection control.. 2017 6 :87. Epub 08/29/2017.

Immunogenicity of AS03-adjuvanted and non-adjuvanted trivalent inactivated influenza vaccines in elderly adults: A Phase 3, randomized trial and post-hoc correlate of protection analysis.

Ruiz-Palacios GM, Leroux-Roels G, Beran J, Devaster JM, Esen M, Launay O, McElhaney JE, van Essen GA, Benoit A, Claeys C, Dewé W, Durand C, Duval X, Falsey AR, Feldman G, Galtier F, Gervais P, Hwang SJ, McNeil S, Richardus JH, Trofa A, Oostvogels L,

Human vaccines & immunotherapeutics.. 2016 December 12 (12):3043-3055. Epub 1900 01 01.

The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ

Scientific reports.. 2016 September 236 :33994. Epub 09/23/2016.

Challenges and opportunities in RSV vaccine development: Meeting report from FDA/NIH workshop.

Roberts JN, Graham BS, Karron RA, Munoz FM, Falsey AR, Anderson LJ, Marshall V, Kim S, Beeler JA

Vaccine.. 2016 September 2234 (41):4843-4849. Epub 08/25/2016.

Parainfluenza Virus Infection.

Branche AR, Falsey AR

Seminars in respiratory and critical care medicine.. 2016 August 37 (4):538-54. Epub 08/03/2016.

Treatment with novel RSV Ig RI-002 controls viral replication and reduces pulmonary damage in immunocompromised Sigmodon hispidus.

Boukhvalova M, Blanco JC, Falsey AR, Mond J

Bone marrow transplantation.. 2016 January 51 (1):119-26. Epub 09/14/2015.

Provider Decisions to Treat Respiratory Illnesses with Antibiotics: Insights from a Randomized Controlled Trial.

Branche AR, Walsh EE, Jadhav N, Karmally R, Baran A, Peterson DR, Falsey AR

PloS one.. 2016 11 (4):e0152986. Epub 04/04/2016.

Development of Electrochemiluminescent Serology Assays to Measure the Humoral Response to Antigens of Respiratory Syncytial Virus.

Maifeld SV, Ro B, Mok H, Chu M, Yu L, Yamagata R, Leonardson T, Chio V, Parhy B, Park S, Carlson M, Machhi S, Ulbrandt N, Falsey AR, Walsh EE, Wang CK, Esser MT, Zuo F

PloS one.. 2016 11 (4):e0153019. Epub 04/12/2016.

Serum Procalcitonin Measurement and Viral Testing to Guide Antibiotic Use for Respiratory Infections in Hospitalized Adults: A Randomized Controlled Trial.

Branche AR, Walsh EE, Vargas R, Hulbert B, Formica MA, Baran A, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2015 December 1212 (11):1692-700. Epub 04/24/2015.

Should clinical case definitions of influenza in hospitalized older adults include fever?

Falsey AR, Baran A, Walsh EE

Influenza and other respiratory viruses.. 2015 August 9 Suppl 1 (Suppl 1):23-9. Epub 1900 01 01.

The Global Influenza Initiative recommendations for the vaccination of pregnant women against seasonal influenza.

Macias AE, Precioso AR, Falsey AR,

Influenza and other respiratory viruses.. 2015 August 9 Suppl 1 (Suppl 1):31-7. Epub 1900 01 01.

Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.

Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, Gregoretti IV, Popova L, Kaminiski D, Fucile CF, Albizua I, Kyu S, Chiang KY, Bradley KT, Burack R, Slifka M, Hammarlund E, Wu H, Zhao L, Walsh EE, Falsey AR, Randall TD, Cheung WC, Sanz I, Lee FE

Immunity.. 2015 July 2143 (1):132-45. Epub 07/14/2015.

Superiority of transcriptional profiling over procalcitonin for distinguishing bacterial from viral lower respiratory tract infections in hospitalized adults.

Suarez NM, Bunsow E, Falsey AR, Walsh EE, Mejias A, Ramilo O

The Journal of infectious diseases.. 2015 July 15212 (2):213-22. Epub 01/29/2015.

Addressing a challenge with a challenge. Investigating respiratory syncytial virus immunity with the human challenge model.

Falsey AR

American journal of respiratory and critical care medicine.. 2015 May 1191 (9):975-7. Epub 1900 01 01.

Diversifying Selection Analysis Predicts Antigenic Evolution of 2009 Pandemic H1N1 Influenza A Virus in Humans.

Lee AJ, Das SR, Wang W, Fitzgerald T, Pickett BE, Aevermann BD, Topham DJ, Falsey AR, Scheuermann RH

Journal of virology.. 2015 May 89 (10):5427-40. Epub 03/04/2015.

Respiratory syncytial virus infection in older adults: an under-recognized problem.

Branche AR, Falsey AR

Drugs & aging.. 2015 April 32 (4):261-9. Epub 1900 01 01.

Safety and immunogenicity of a quadrivalent intradermal influenza vaccine in adults.

Gorse GJ, Falsey AR, Ozol-Godfrey A, Landolfi V, Tsang PH

Vaccine.. 2015 February 2533 (9):1151-9. Epub 01/19/2015.

Detection of respiratory viruses in sputum from adults by use of automated multiplex PCR.

Branche AR, Walsh EE, Formica MA, Falsey AR

Journal of clinical microbiology.. 2014 October 52 (10):3590-6. Epub 07/23/2014.

Influenza symptoms and their impact on elderly adults: randomised trial of AS03-adjuvanted or non-adjuvanted inactivated trivalent seasonal influenza vaccines.

van Essen GA, Beran J, Devaster JM, Durand C, Duval X, Esen M, Falsey AR, Feldman G, Gervais P, Innis BL, Kovac M, Launay O, Leroux-Roels G, McElhaney JE, McNeil S, Oujaa M, Richardus JH, Ruiz-Palacios G, Osborne RH, Oostvogels L

Influenza and other respiratory viruses.. 2014 July 8 (4):452-62. Epub 04/04/2014.

Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness.

Falsey AR, McElhaney JE, Beran J, van Essen GA, Duval X, Esen M, Galtier F, Gervais P, Hwang SJ, Kremsner P, Launay O, Leroux-Roels G, McNeil SA, Nowakowski A, Richardus JH, Ruiz-Palacios G, St Rose S, Devaster JM, Oostvogels L, Durviaux S, Taylor S

The Journal of infectious diseases.. 2014 June 15209 (12):1873-81. Epub 01/29/2014.

Priming for pandemic influenza: thanks for the memories.

Falsey AR

The Journal of infectious diseases.. 2014 June 15209 (12):1857-9. Epub 03/05/2014.

Respiratory syncytial virus in hematopoietic cell transplant recipients: factors determining progression to lower respiratory tract disease.

Kim YJ, Guthrie KA, Waghmare A, Walsh EE, Falsey AR, Kuypers J, Cent A, Englund JA, Boeckh M

The Journal of infectious diseases.. 2014 April 15209 (8):1195-204. Epub 12/23/2013.

Reply to Musher et al.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 2014 February 15209 (4):633-5. Epub 11/11/2013.

Blood collection tubes influence serum ficolin-1 and ficolin-2 levels.

Brady AM, Spencer BL, Falsey AR, Nahm MH

Clinical and vaccine immunology : CVI.. 2014 January 21 (1):51-5. Epub 10/30/2013.

Safety and immunogenicity of revaccination with reduced dose intradermal and standard dose intramuscular influenza vaccines in adults 18-64 years of age.

Gorse GJ, Falsey AR, Johnson CM, Morrison D, Fried DL, Ervin JE, Greenberg DP, Ozol-Godfrey A, Landolfi V, Tsang PH

Vaccine.. 2013 December 531 (50):6034-40. Epub 09/20/2013.

Clinical impact of human coronaviruses 229E and OC43 infection in diverse adult populations.

Walsh EE, Shin JH, Falsey AR

The Journal of infectious diseases.. 2013 November 15208 (10):1634-42. Epub 08/06/2013.

Editorial commentary: respiratory syncytial virus: a global pathogen in an aging world.

Falsey AR

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2013 October 57 (8):1078-80. Epub 07/21/2013.

Bacterial complications of respiratory tract viral illness: a comprehensive evaluation.

Falsey AR, Becker KL, Swinburne AJ, Nylen ES, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Baran A, Walsh EE

The Journal of infectious diseases.. 2013 August 1208 (3):432-41. Epub 05/09/2013.

AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial.

McElhaney JE, Beran J, Devaster JM, Esen M, Launay O, Leroux-Roels G, Ruiz-Palacios GM, van Essen GA, Caplanusi A, Claeys C, Durand C, Duval X, El Idrissi M, Falsey AR, Feldman G, Frey SE, Galtier F, Hwang SJ, Innis BL, Kovac M, Kremsner P, McNeil S, Nowakowski A, Richardus JH, Trofa A, Oostvogels L,

The Lancet. Infectious diseases.. 2013 June 13 (6):485-96. Epub 03/19/2013.

Risk factors for respiratory syncytial virus illness among patients with chronic obstructive pulmonary disease.

Mehta J, Walsh EE, Mahadevia PJ, Falsey AR

COPD.. 2013 June 10 (3):293-9. Epub 03/28/2013.

Viral shedding and immune responses to respiratory syncytial virus infection in older adults.

Walsh EE, Peterson D, Kalkanoglu A, Lee FE, Falsey AR

The Journal of infectious diseases.. 2013 May 1207 (9):1424-32. Epub 02/04/2013.

Intradermally-administered influenza virus vaccine is safe and immunogenic in healthy adults 18-64 years of age.

Gorse GJ, Falsey AR, Fling JA, Poling TL, Strout CB, Tsang PH

Vaccine.. 2013 May 131 (19):2358-65. Epub 03/13/2013.

Can serum procalcitonin levels help interpret indeterminate chest radiographs in patients hospitalized with acute respiratory illness?

Walsh EE, Swinburne AJ, Becker KL, Nylen ES, Snider RH, Baran A, Peterson DR, Falsey AR

Journal of hospital medicine.. 2013 February 8 (2):61-7. Epub 10/19/2012.

Consequences of immature and senescent immune responses for infection with respiratory syncytial virus.

Malloy AM, Falsey AR, Ruckwardt TJ

Current topics in microbiology and immunology.. 2013 372 :211-31. Epub 1900 01 01.

Factors associated with symptomatic rhinovirus infection in patients with COPD.

Gandhi A, Walsh EE, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Baran A, Falsey AR

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2012 December 55 (4):343-7. Epub 09/19/2012.

Simple method for combining sputum and nasal samples for virus detection by reverse transcriptase PCR.

Falsey AR, Formica MA, Walsh EE

Journal of clinical microbiology.. 2012 August 50 (8):2835. Epub 06/12/2012.

Respiratory syncytial virus infection in adult populations.

Walsh EE, Falsey AR

Infectious disorders drug targets.. 2012 April 12 (2):98-102. Epub 1900 01 01.

Yield of sputum for viral detection by reverse transcriptase PCR in adults hospitalized with respiratory illness.

Falsey AR, Formica MA, Walsh EE

Journal of clinical microbiology.. 2012 January 50 (1):21-4. Epub 11/16/2011.

A randomized, controlled trial of Panax quinquefolius extract (CVT-E002) to reduce respiratory infection in patients with chronic lymphocytic leukemia.

High KP, Case D, Hurd D, Powell B, Lesser G, Falsey AR, Siegel R, Metzner-Sadurski J, Krauss JC, Chinnasami B, Sanders G, Rousey S, Shaw EG

The journal of supportive oncology.. 2012 10 (5):195-201. Epub 01/23/2012.

Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note.

Falsey AR, Becker KL, Swinburne AJ, Nylen ES, Snider RH, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Walsh EE

International journal of chronic obstructive pulmonary disease.. 2012 7 :127-35. Epub 02/23/2012.

Current management of parainfluenza pneumonitis in immunocompromised patients: a review.

Falsey AR

Infection and drug resistance.. 2012 5 :121-7. Epub 08/08/2012.

The effect of steroid use in hospitalized adults with respiratory syncytial virus-related illness.

Lee FE, Walsh EE, Falsey AR

Chest.. 2011 November 140 (5):1155-1161. Epub 05/12/2011.

Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop.

Hanania NA, King MJ, Braman SS, Saltoun C, Wise RA, Enright P, Falsey AR, Mathur SK, Ramsdell JW, Rogers L, Stempel DA, Lima JJ, Fish JE, Wilson SR, Boyd C, Patel KV, Irvin CG, Yawn BP, Halm EA, Wasserman SI, Sands MF, Ershler WB, Ledford DK,

The Journal of allergy and clinical immunology.. 2011 September 128 (3 Suppl):S4-24. Epub 1900 01 01.

Prevalence of specific neutralizing antibodies against Sendai virus in populations from different geographic areas: implications for AIDS vaccine development using Sendai virus vectors.

Hara H, Hara H, Hironaka T, Inoue M, Iida A, Shu T, Hasegawa M, Nagai Y, Falsey AR, Kamali A, Anzala O, Sanders EJ, Karita E, Mwananyanda L, Vasan S, Lombardo A, Parks CL, Sayeed E, Krebs M, Cormier E, Ackland J, Price MA, Excler JL

Human vaccines. 2011 June 7 (6):639-45. Epub 06/01/2011.

Circulating human antibody-secreting cells during vaccinations and respiratory viral infections are characterized by high specificity and lack of bystander effect.

Lee FE, Halliley JL, Walsh EE, Moscatiello AP, Kmush BL, Falsey AR, Randall TD, Kaminiski DA, Miller RK, Sanz I

The Journal of immunology : official journal of the American Association of Immunologists.. 2011 May 1186 (9):5514-21. Epub 03/25/2011.

Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults.

Lee FE, Falsey AR, Halliley JL, Sanz I, Walsh EE

The Journal of infectious diseases.. 2010 December 1202 (11):1659-66. Epub 10/27/2010.

New emerging technologies and the intradermal route: the novel way to immunize against influenza.

Falsey AR

Vaccine.. 2010 September 728 Suppl 4 :D24-32. Epub 1900 01 01.

Clinical and immunologic predictors of influenza illness among vaccinated older adults.

Shahid Z, Kleppinger A, Gentleman B, Falsey AR, McElhaney JE

Vaccine.. 2010 August 3128 (38):6145-51. Epub 07/31/2010.

Humoral response to the central unglycosylated region of the respiratory syncytial virus attachment protein.

Murata Y, Lightfoote PM, Biear JN, Falsey AR, Walsh EE

Vaccine.. 2010 August 3128 (38):6242-6. Epub 07/23/2010.

Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization.

Halliley JL, Kyu S, Kobie JJ, Walsh EE, Falsey AR, Randall TD, Treanor J, Feng C, Sanz I, Lee FE

Vaccine.. 2010 April 3028 (20):3582-7. Epub 03/16/2010.

Identification of and human serum reactogenicity to neutralizing epitopes within the central unglycosylated region of the respiratory syncytial virus attachment protein.

Murata Y, Lightfoote PM, Falsey AR, Walsh EE

Clinical and vaccine immunology : CVI.. 2010 April 17 (4):695-7. Epub 02/17/2010.

The diagnosis of viral respiratory disease in older adults.

Talbot HK, Falsey AR

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2010 March 150 (5):747-51. Epub 1900 01 01.

Humoral immunity to human metapneumovirus infection in adults.

Falsey AR, Hennessey PA, Formica MA, Criddle MM, Biear JM, Walsh EE

Vaccine.. 2010 February 1028 (6):1477-80. Epub 12/08/2009.

Microneutralization assay for the measurement of neutralizing antibodies to human metapneumovirus.

Falsey AR, Formica MA, Walsh EE

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2009 December 46 (4):314-7. Epub 10/08/2009.

Risk factors for respiratory failure associated with respiratory syncytial virus infection in adults.

Duncan CB, Walsh EE, Peterson DR, Lee FE, Falsey AR

The Journal of infectious diseases.. 2009 October 15200 (8):1242-6. Epub 1900 01 01.

Randomized, double-blind controlled phase 3 trial comparing the immunogenicity of high-dose and standard-dose influenza vaccine in adults 65 years of age and older.

Falsey AR, Treanor JJ, Tornieporth N, Capellan J, Gorse GJ

The Journal of infectious diseases.. 2009 July 15200 (2):172-80. Epub 1900 01 01.

Half-dose influenza vaccine: stretching the supply or wasting it?

Falsey AR

Archives of internal medicine.. 2008 December 8168 (22):2402-3. Epub 1900 01 01.

Human metapneumovirus infections in adults: another piece of the puzzle.

Walsh EE, Peterson DR, Falsey AR

Archives of internal medicine.. 2008 December 8168 (22):2489-96. Epub 1900 01 01.

Viral pathogens in acute exacerbations of chronic obstructive pulmonary disease.

Camargo CA, Ginde AA, Clark S, Cartwright CP, Falsey AR, Niewoehner DE

Internal and emergency medicine.. 2008 December 3 (4):355-9. Epub 09/30/2008.

Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals.

Falsey AR, Walsh EE, Capellan J, Gravenstein S, Zambon M, Yau E, Gorse GJ, Edelman R, Hayden FG, McElhaney JE, Neuzil KM, Nichol KL, Simões EA, Wright PF, Sales VM

The Journal of infectious diseases.. 2008 November 1198 (9):1317-26. Epub 1900 01 01.

Human metapneumovirus infection in adults.

Falsey AR

The Pediatric infectious disease journal.. 2008 October 27 (10 Suppl):S80-3. Epub 1900 01 01.

Detection of genetic lineages of human metapneumovirus in Croatia during the winter season 2005/2006.

Ljubin-Sternak S, Santak M, Cepin-Bogovi? J, Ba?e A, Vojnovi? G, Mlinari?-Galinovi? G, Forci? D, Drazenovi? V, Falsey AR

Journal of medical virology.. 2008 July 80 (7):1282-7. Epub 1900 01 01.

Long-term care facilities: a cornucopia of viral pathogens.

Falsey AR, Dallal GE, Formica MA, Andolina GG, Hamer DH, Leka LL, Meydani SN

Journal of the American Geriatrics Society.. 2008 July 56 (7):1281-5. Epub 06/28/2008.

RSV 2007: recent advances in respiratory syncytial virus research.

Stevens WW, Falsey AR, Braciale TJ

Viral immunology.. 2008 June 21 (2):133-40. Epub 1900 01 01.

Genetic analysis of p53 nuclear importation.

Li Q, Falsey RR, Gaitonde S, Sotello V, Kislin K, Martinez JD

Oncogene.. 2007 December 1326 (57):7885-93. Epub 06/18/2007.

Community-acquired viral pneumonia.

Falsey AR

Clinics in geriatric medicine.. 2007 August 23 (3):535-52, vi. Epub 1900 01 01.

Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection.

Lee FE, Walsh EE, Falsey AR, Lumb ME, Okam NV, Liu N, Divekar AA, Hall CB, Mosmann TR

The Journal of infectious diseases.. 2007 June 15195 (12):1779-88. Epub 05/09/2007.

Pulmonary complications of interpandemic influenza A in hospitalized adults.

Murata Y, Walsh EE, Falsey AR

The Journal of infectious diseases.. 2007 April 1195 (7):1029-37. Epub 02/15/2007.

Is clinical recognition of respiratory syncytial virus infection in hospitalized elderly and high-risk adults possible?

Walsh EE, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2007 April 1195 (7):1046-51. Epub 02/15/2007.

Respiratory syncytial virus infection in adults.

Falsey AR

Seminars in respiratory and critical care medicine.. 2007 April 28 (2):171-81. Epub 1900 01 01.

Impact of rapid diagnosis on management of adults hospitalized with influenza.

Falsey AR, Murata Y, Walsh EE

Archives of internal medicine.. 2007 February 26167 (4):354-60. Epub 01/22/2007.

Respiratory syncytial virus infection in adults.

Murata Y, Falsey AR

Antiviral therapy.. 2007 12 (4 Pt B):659-70. Epub 1900 01 01.

Serosurvey of human metapneumovirus infection in Croatia.

Ljubin Sternak S, Vilibi? Cavlek T, Falsey AR, Walsh EE, Mlinari? Galinovi? G

Croatian medical journal.. 2006 December 47 (6):878-81. Epub 1900 01 01.

Serum antibody decay in adults following natural respiratory syncytial virus infection.

Falsey AR, Singh HK, Walsh EE

Journal of medical virology.. 2006 November 78 (11):1493-7. Epub 1900 01 01.

Detection of respiratory syncytial virus in adults with chronic obstructive pulmonary disease.

Falsey AR, Formica MA, Hennessey PA, Criddle MM, Sullender WM, Walsh EE

American journal of respiratory and critical care medicine.. 2006 March 15173 (6):639-43. Epub 12/30/2005.

Viral pneumonia in older adults.

Falsey AR, Walsh EE

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2006 February 1542 (4):518-24. Epub 01/06/2006.

Detection of respiratory syncytial virus and human metapneumovirus by reverse transcription polymerase chain reaction in adults with and without respiratory illness.

Falsey AR, Criddle MC, Walsh EE

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2006 January 35 (1):46-50. Epub 1900 01 01.

The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects.

Lee FE, Walsh EE, Falsey AR, Liu N, Liu D, Divekar A, Snyder-Cappione JE, Mosmann TR

Mechanisms of ageing and development.. 2005 November 126 (11):1223-9. Epub 1900 01 01.

Respiratory syncytial virus infection in elderly and high-risk adults.

Falsey AR

Experimental lung research.. 2005 September 31 Suppl 1 :77. Epub 1900 01 01.

Respiratory syncytial virus infection in elderly and high-risk adults.

Falsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE

The New England journal of medicine.. 2005 April 28352 (17):1749-59. Epub 1900 01 01.

Respiratory syncytial virus infection in elderly adults.

Falsey AR, Walsh EE

Drugs & aging.. 2005 22 (7):577-87. Epub 1900 01 01.

Respiratory syncytial virus and other pneumoviruses: a review of the international symposium--RSV 2003.

Schmidt AC, Johnson TR, Openshaw PJ, Braciale TJ, Falsey AR, Anderson LJ, Wertz GW, Groothuis JR, Prince GA, Melero JA, Graham BS

Virus research.. 2004 November 106 (1):1-13. Epub 1900 01 01.

Experimental infection of humans with A2 respiratory syncytial virus.

Lee FE, Walsh EE, Falsey AR, Betts RF, Treanor JJ

Antiviral research.. 2004 September 63 (3):191-6. Epub 1900 01 01.

Humoral and mucosal immunity in protection from natural respiratory syncytial virus infection in adults.

Walsh EE, Falsey AR

The Journal of infectious diseases.. 2004 July 15190 (2):373-8. Epub 06/18/2004.

Age related differences in humoral immune response to respiratory syncytial virus infection in adults.

Walsh EE, Falsey AR

Journal of medical virology.. 2004 June 73 (2):295-9. Epub 1900 01 01.

Risk factors for severe respiratory syncytial virus infection in elderly persons.

Walsh EE, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2004 January 15189 (2):233-8. Epub 01/09/2004.

Lack of sensitivity of rapid antigen tests for the diagnosis of respiratory syncytial virus infection in adults.

Casiano-Colón AE, Hulbert BB, Mayer TK, Walsh EE, Falsey AR

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2003 October 28 (2):169-74. Epub 1900 01 01.

The stress response: implications for the clinical development of hsp90 inhibitors.

Whitesell L, Bagatell R, Falsey R

Current cancer drug targets.. 2003 October 3 (5):349-58. Epub 1900 01 01.

Comparison of quantitative reverse transcription-PCR to viral culture for assessment of respiratory syncytial virus shedding.

Falsey AR, Formica MA, Treanor JJ, Walsh EE

Journal of clinical microbiology.. 2003 September 41 (9):4160-5. Epub 1900 01 01.

Novel coronavirus and severe acute respiratory syndrome.

Falsey AR, Walsh EE

Lancet.. 2003 April 19361 (9366):1312-3. Epub 1900 01 01.

Protein S declines during winter respiratory infections.

Kaba NK, Francis CW, Hall WJ, Falsey AR, Smith BH

Journal of thrombosis and haemostasis : JTH.. 2003 April 1 (4):729-34. Epub 1900 01 01.

Human metapneumovirus infections in young and elderly adults.

Falsey AR, Erdman D, Anderson LJ, Walsh EE

The Journal of infectious diseases.. 2003 March 1187 (5):785-90. Epub 02/24/2003.

Clinical features of influenza A virus infection in older hospitalized persons.

Walsh EE, Cox C, Falsey AR

Journal of the American Geriatrics Society.. 2002 September 50 (9):1498-503. Epub 1900 01 01.

Rhinovirus and coronavirus infection-associated hospitalizations among older adults.

Falsey AR, Walsh EE, Hayden FG

The Journal of infectious diseases.. 2002 May 1185 (9):1338-41. Epub 04/16/2002.

Effect of aging on cytokine production in response to respiratory syncytial virus infection.

Looney RJ, Falsey AR, Walsh E, Campbell D

The Journal of infectious diseases.. 2002 March 1185 (5):682-5. Epub 02/14/2002.

Diagnosis of respiratory syncytial virus infection: comparison of reverse transcription-PCR to viral culture and serology in adults with respiratory illness.

Falsey AR, Formica MA, Walsh EE

Journal of clinical microbiology.. 2002 March 40 (3):817-20. Epub 1900 01 01.

Antivirals for influenza: what is their role in the older patient?

Dumyati G, Falsey AR

Drugs & aging.. 2002 19 (10):777-86. Epub 1900 01 01.

Staphylococcus aureus cholecystitis: a report of three cases with review of the literature.

Merchant SS, Falsey AR

The Yale journal of biology and medicine.. 2002 75 (5-6):285-91. Epub 1900 01 01.

Response of C-reactive protein and serum amyloid A to influenza A infection in older adults.

Falsey AR, Walsh EE, Francis CW, Looney RJ, Kolassa JE, Hall WJ, Abraham GN

The Journal of infectious diseases.. 2001 April 1183 (7):995-9. Epub 02/23/2001.

Prothrombotic changes in hemostatic parameters and C-reactive protein in the elderly with winter acute respiratory tract infections.

Horan JT, Francis CW, Falsey AR, Kolassa J, Smith BH, Hall WJ

Thrombosis and haemostasis.. 2001 February 85 (2):245-9. Epub 1900 01 01.

Hepatitis B immunization of healthy elderly adults: relationship between naïve CD4+ T cells and primary immune response and evaluation of GM-CSF as an adjuvant.

Looney RJ, Hasan MS, Coffin D, Campbell D, Falsey AR, Kolassa J, Agosti JM, Abraham GN, Evans TG

Journal of clinical immunology.. 2001 January 21 (1):30-6. Epub 1900 01 01.

Respiratory syncytial virus infection in adults.

Falsey AR, Walsh EE

Clinical microbiology reviews.. 2000 July 13 (3):371-84. Epub 1900 01 01.

Evaluation of the live attenuated cpts 248/404 RSV vaccine in combination with a subunit RSV vaccine (PFP-2) in healthy young and older adults.

Gonzalez IM, Karron RA, Eichelberger M, Walsh EE, Delagarza VW, Bennett R, Chanock RM, Murphy BR, Clements-Mann ML, Falsey AR

Vaccine.. 2000 March 618 (17):1763-72. Epub 1900 01 01.

Respiratory viral infections in the elderly.

Treanor J, Falsey A

Antiviral research.. 1999 December 1544 (2):79-102. Epub 1900 01 01.

Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults.

Falsey AR, Walsh EE, Looney RJ, Kolassa JE, Formica MA, Criddle MC, Hall WJ

Journal of medical virology.. 1999 October 59 (2):221-6. Epub 1900 01 01.

Respiratory syncytial and other virus infections in persons with chronic cardiopulmonary disease.

Walsh EE, Falsey AR, Hennessey PA

American journal of respiratory and critical care medicine.. 1999 September 160 (3):791-5. Epub 1900 01 01.

A simple and reproducible method for collecting nasal secretions in frail elderly adults, for measurement of virus-specific IgA.

Walsh EE, Falsey AR

The Journal of infectious diseases.. 1999 May 179 (5):1268-73. Epub 1900 01 01.

Evaluation of a handwashing intervention to reduce respiratory illness rates in senior day-care centers.

Falsey AR, Criddle MM, Kolassa JE, McCann RM, Brower CA, Hall WJ

Infection control and hospital epidemiology.. 1999 March 20 (3):200-2. Epub 1900 01 01.

Role of cytomegalovirus in the T cell changes seen in elderly individuals.

Looney RJ, Falsey A, Campbell D, Torres A, Kolassa J, Brower C, McCann R, Menegus M, McCormick K, Frampton M, Hall W, Abraham GN

Clinical immunology : the official journal of the Clinical Immunology Society.. 1999 February 90 (2):213-9. Epub 1900 01 01.

Respiratory syncytial virus infection in older persons.

Falsey AR

Vaccine.. 1998 November 16 (18):1775-8. Epub 1900 01 01.

Monoclonal antibody neutralization escape mutants of respiratory syncytial virus with unique alterations in the attachment (G) protein.

Walsh EE, Falsey AR, Sullender WM

The Journal of general virology.. 1998 March 79 ( Pt 3) :479-87. Epub 1900 01 01.

Relationship of serum antibody to risk of respiratory syncytial virus infection in elderly adults.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 1998 February 177 (2):463-6. Epub 1900 01 01.

The "common cold" in frail older persons: impact of rhinovirus and coronavirus in a senior daycare center.

Falsey AR, McCann RM, Hall WJ, Criddle MM, Formica MA, Wycoff D, Kolassa JE

Journal of the American Geriatrics Society.. 1997 June 45 (6):706-11. Epub 1900 01 01.

Respiratory syncytial virus infection in the elderly.

Mlinaric-Galinovic G, Falsey AR, Walsh EE

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.. 1996 October 15 (10):777-81. Epub 1900 01 01.

Evaluation of four methods for the diagnosis of respiratory syncytial virus infection in older adults.

Falsey AR, McCann RM, Hall WJ, Criddle MM

Journal of the American Geriatrics Society.. 1996 January 44 (1):71-3. Epub 1900 01 01.

Respiratory syncytial virus and influenza A infections in the hospitalized elderly.

Falsey AR, Cunningham CK, Barker WH, Kouides RW, Yuen JB, Menegus M, Weiner LB, Bonville CA, Betts RF

The Journal of infectious diseases.. 1995 August 172 (2):389-94. Epub 1900 01 01.

Acute respiratory tract infection in daycare centers for older persons.

Falsey AR, McCann RM, Hall WJ, Tanner MA, Criddle MM, Formica MA, Irvine CS, Kolassa JE, Barker WH, Treanor JJ

Journal of the American Geriatrics Society.. 1995 January 43 (1):30-6. Epub 1900 01 01.

Transmission of Chlamydia pneumoniae.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 1993 August 168 (2):493-6. Epub 1900 01 01.

Viral respiratory infections in the institutionalized elderly: clinical and epidemiologic findings.

Falsey AR, Treanor JJ, Betts RF, Walsh EE

Journal of the American Geriatrics Society.. 1992 February 40 (2):115-9. Epub 1900 01 01.

Humoral immunity to respiratory syncytial virus infection in the elderly.

Falsey AR, Walsh EE

Journal of medical virology.. 1992 January 36 (1):39-43. Epub 1900 01 01.

Noninfluenza respiratory virus infection in long-term care facilities.

Falsey AR

Infection control and hospital epidemiology.. 1991 October 12 (10):602-8. Epub 1900 01 01.

Serologic evidence of respiratory syncytial virus infection in nursing home patients.

Falsey AR, Walsh EE, Betts RF

The Journal of infectious diseases.. 1990 August 162 (2):568-9. Epub 1900 01 01.

Fatal subcutaneous aspergillosis following necrotizing fasciitis: a case report.

Falsey AR, Goldsticker RD, Ahern MJ

The Yale journal of biology and medicine.. 1990 63 (1):9-13. Epub 1900 01 01.

Books

Genomic and Precision Medicine - Infectious and Inflammatory Disease. (2019)

Chapter: Respiratory Viral Infections

Authors: Falsey AR

Publisher: Elsevier 2019

International Encyclopedia of Public Health and Infectious Diseases (2018)

Chapter: Rhinoviruses

Authors: Branche AR, Falsey AR

Publisher: Elsevier 2018

Principles and Practice of Infectious Diseases, 8th ed (2014)

Chapter: Human Metapneumovirus

Authors: Falsey AR

Publisher: University of Chicago Press 2014

Current Topics in Microbiology and Immunology (2013)

Chapter: Consequences of Immature and Senescent Immune Responses for Infection with RSV

Authors: 21. Malloy AM, Falsey AR, Ruckwardt t

Publisher: Springer Publishing 2013

Infectious Disorders-Drug Targets (2011)

Chapter: Respiratory Syncytial Virus in Adults

Authors: Walsh EE, Falsey AR

Publisher: Bentham 2011

Infectious Disease in the Aging (2009)

Chapter: Viral Infections

Authors: Duncan CB, Falsey AR

Publisher: Humana 2009

Perspectives in Medical Virology:Respiratory Syncytial Virus (2007)

Chapter: RSV infection in Eldery Adults

Authors: Murata Y and falsey AR

Publisher: Elsevier Life Sciences, London 2007

Antibiotic Therapy for Geriatric Patients (2005)

Chapter: Common Viral Infections

Authors: Falsey AR

Publisher: Marcel Dekker Inc. 2005

Principles and Practice of Geriatric Medicine (2005)

Chapter: Infectious Disease

Authors: Falsey AR

Publisher: John Wiley & Sons Ltd. 2005

Principles and Practice of Infectious Diseases (2004)

Chapter: Human Metapneumovirus

Authors: Falsey AR

Publisher: University of Chicago Press 2004

Antimicrobial Therapy and Vaccines (2003)

Chapter: Respiratory Syncytial Virus

Authors: Walsh EE and Falsey AR

Publisher: Apple Tree Production 2003

Community Acquired Pneumonia (2001)

Chapter: Respiratory Syncytial Virus Pneumonia

Authors: Falsey AR

Publisher: Plenum Press 2001

Infections and Infection Control in Long Term Care Facilities (2001)

Chapter: Influenza and other Respiratory Viruses

Authors: Dumyati G, Falsey AR

Publisher: Marcel Dekker Inc 2001

Infectious Disease in Aging (2000)

Chapter: Viral Infections

Authors: Falsey AR

Publisher: Humana Press 2000

Viral Infection of the lung (1999)

Chapter: Viral Pulmonary Infections in Older Persons

Authors: Falsey AR

Publisher: Marcel Dekker Inc 1999

Principles and Practice of Geriatric Medicine (1998)

Chapter: Aging and Infectious Disease

Authors: Falsey AR

Publisher: John Wiley & Sons Ltd 1998

Oxford Textbook of Geriatric Medicine. (1998)

Chapter: Epidemiology of Infections in Older Persons

Authors: Falsey AR

Publisher: Oxford University Press 1998

Primary Care for Women (1997)

Chapter: Cardiovascular Antibiotic Prophylaxis

Authors: Falsey AR

Publisher: Lippincott-Raven 1997

Infectious Disease and Antimicrobial Therapy of the Ears, Nose and Throat (1997)

Chapter: Viruses

Authors: Falsey AR, Hall CB

Publisher: WB Saunders 1997

Atlas of Internal Medicine (1996)

Chapter: Viral Pneumonias

Authors: Betts RF, Falsey AR

Publisher: Current Medicine 1996

Oxford Textbook of Geriatric Medicine (1992)

Chapter: Contol of Infections

Authors: Falsey AR, Bentley DW

Publisher: Oxford University Press 1992

Respiratory Infections in the Elderly (1991)

Chapter: The Common Cold

Authors: Falsey AR, Betts RF

Publisher: Raven Press 1991