Dr. Sonal Munsiff is board-certified in Infectious Diseases. She manages many acute and chronic infections mostly in the outpatient clinic setting, with particular interest in bone and joint infections, orthopedic hardware, and device related infections, infections with drug resistant organism, HIV and AIDS, and mycobacterial infections. She is working with a multidisciplinary staff to manage Outpatient IV antibiotic patients for the institution. She will be teaching "Epidemiology of Infectious Disease" Course in the Epidemiology Division of the School of Medicine and Dentistry in Fall 2017.
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Previously she has worked in the field of TB control for 15 years with the NYC Bureau of Tuberculosis Control, and with CDC. She served as the Director of Epidemiology for the Program for several years, and then was Director and Assistant Commissioner of the program for 7 years. She has conducted research on various aspects of TB, particularly drug-resistant TB, complications and treatment of TB in HIV-infected persons, transmission and molecular epidemiology of TB, outbreak investigations, and program evaluation. She was co-investigator for the CDC TB clinical rails Unit on studying Moxifloxacin for TB treatment. She has authored over 60 medical publications, including the NYC "TB manual".

Faculty Appointments

Associate Professor - Department of Medicine, Infectious Diseases (SMD)

Credentials

Residency & Fellowship

Fellowship, Infectious Disease, Montefiore Medical Center-North Division/Wakefield. 1993 - 1995

Residency, Internal Medicine, Columbia University Irving Medical Center. 1990 - 1992

Internship, Internal Medicine, Beth Israel Deaconess Medical Center-Main Campus. 1989 - 1990

Education

MD | New York University School of Medicine. 1989

Research

Dr. Munsiff's current research interests include optimal diagnosis and management of osteomyelitis, usefulness of the Interferon gamma release assays for diagnosis of latent TB infection, and diagnosis and management of non tuberculous mycobacterial diseases.

Previously she has worked in the field of TB control for 15 years and has conducted research on various aspects of TB, particularly drug-resistant TB, complications and treatment of TB in HIV-infected persons, transmission and molecular epidemiology of TB, outbreak investigations, and program evaluation. She was co-investigator for the CDC TB clinical rails Unit on studying Moxifloxacin for TB treatment. She has authored over 60 medical publications, including the NYC "TB manual".

Clinical Trials

Safety, Tolerability, and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

Lead Researcher: Sonal Munsiff

This study will asses the safety of an oral medication, called Selgantolimod, which may help reduce the amount of hepatitis B virus in the blood. In this study, Selgantolimod will be given over a 6-month period to participants that are dually infecte...

Randomized, Controlled Trial to Evaluate the Anti-inflammatory Efficacy of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive ART and Its Effect on Chronic Inflammation, HIV Persistence, and Other Clinical Outcomes

Lead Researcher: Sonal Munsiff

This study will determine if the drug, letermovir, is an anti-inflammatory in adults with HIV and asymptomatic cytomegalovirus (CMV) who are on anti-HIV medications and whose HIV is suppressed. Participants will be randomly assigned to receive either...

Publications

Journal Articles

Daily fosfomycin versus levofloxacin for complicated urinary tract infections.

Rouphael N, Winokur P, Keefer MC, Traenkner J, Drobeniuc A, Doi Y, Munsiff S, Fowler VG, Evans S, Oler RE, Tuyishimire B, Lee M, Ghazaryan V, Chambers HF,

mBio.. 2023 September 12 :e0167723. Epub 09/12/2023.

Prosthetic Joint Infections and Rifampin.

Munsiff S, Louie T

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2022 March 16 Epub 03/16/2022.

Safety and immunogenicity of an AS03-adjuvanted SARS-CoV-2 recombinant protein vaccine (CoV2 preS dTM) in healthy adults: interim findings from a phase 2, randomised, dose-finding, multicentre study.

Sridhar S, Joaquin A, Bonaparte MI, Bueso A, Chabanon AL, Chen A, Chicz RM, Diemert D, Essink BJ, Fu B, Grunenberg NA, Janosczyk H, Keefer MC, Rivera M DM, Meng Y, Michael NL, Munsiff SS, Ogbuagu O, Raabe VN, Severance R, Rivas E, Romanyak N, Rouphael NG, Schuerman L, Sher LD, Walsh SR, White J, von Barbier D, de Bruyn G, Canter R, Grillet MH, Keshtkar-Jahromi M, Koutsoukos M, Lopez D, Masotti R, Mendoza S, Moreau C, Ceregido MA, Ramirez S, Said A, Tavares-Da-Silva F, Shi J, Tong T, Treanor J, Diazgranados CA, Savarino S

The Lancet. Infectious diseases.. 2022 January 25 Epub 01/25/2022.

cavitary lung disease progression over a three year period - A case report.

Croix MC, Munsiff SS

IDCases.. 2022 27 :e01379. Epub 01/05/2022.

Locally recurrent primary cutaneous coccidioidomycosis.

Lee G, Scott GA, Munsiff SS, Richardson CT

JAAD case reports.. 2021 October 16 :161-163. Epub 09/08/2021.

Simplifying outpatient antibiotic stewardship.

Frost HM, Munsiff SS, Lou Y, Jenkins TC

Infection control and hospital epidemiology.. 2021 February 1 :1-2. Epub 02/01/2021.

Long-term Mortality of Patients With Tuberculous Meningitis in New York City: A Cohort Study.

Vinnard C, King L, Munsiff S, Crossa A, Iwata K, Pasipanodya J, Proops D, Ahuja S

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2017 February 1564 (4):401-407. Epub 1900 01 01.

Chronic tenosynovitis of the hand caused by Mycobacterium heraklionense.

Aburjania N, Hammert WC, Bansal M, Boyce BF, Munsiff SS

International journal of mycobacteriology.. 2016 September 5 (3):273-275. Epub 06/16/2016.

Mycobacterium tuberculosis cluster with developing drug resistance, New York, New York, USA, 2003-2009.

Perri BR, Proops D, Moonan PK, Munsiff SS, Kreiswirth BN, Goranson C, Ahuja SD

Emerging infectious diseases.. 2011 March 17 (3):372-378. Epub 1900 01 01.

Street-outreach improves detection but not referral for drug users with latent tuberculosis, New York City.

Factor SH, Sackoff JE, Raj-Singh S, Wu Y, Monserrate J, Munsiff S, Vlahov D

Substance use & misuse.. 2011 46 (14):1711-5. Epub 09/26/2011.

Prevalence of tuberculin skin test positivity in clinical population in New York City.

Li J, Munsiff SS, Agerton TB

Journal of immigrant and minority health. 2010 December 12 (6):816-22. Epub 11/05/2008.

Hospitalizations for tuberculosis in New York City: how many could be avoided?

Thomas JA, Laraque F, Munsiff S, Piatek A, Harris TG

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2010 December 14 (12):1603-12. Epub 1900 01 01.

Achieving international targets for tuberculosis treatment success among HIV-positive patients in New York City.

King L, Munsiff SS, Ahuja SD

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2010 December 14 (12):1613-20. Epub 1900 01 01.

Congenital tuberculosis and management of exposure in three neonatal intensive care units.

Winters A, Agerton TB, Driver CR, Trieu L, O'Flaherty T, Munsiff SS

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2010 December 14 (12):1641-3. Epub 1900 01 01.

Changing sociodemographic and clinical characteristics of tuberculosis among HIV-infected patients, New York City, 1992-2005.

Harris TG, Li J, Hanna DB, Munsiff SS

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2010 June 150 (11):1524-31. Epub 1900 01 01.

Adherence to treatment of latent tuberculosis infection in a clinical population in New York City.

Li J, Munsiff SS, Tarantino T, Dorsinville M

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.. 2010 April 14 (4):e292-7. Epub 08/04/2009.

Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000-06.

Anger HA, Dworkin F, Sharma S, Munsiff SS, Nilsen DM, Ahuja SD

The Journal of antimicrobial chemotherapy.. 2010 April 65 (4):775-83. Epub 02/11/2010.

Treatment outcomes among patients with multidrug-resistant tuberculosis.

Munsiff SS

The Lancet. Infectious diseases.. 2010 April 10 (4):215; author reply 215-6. Epub 1900 01 01.

The impact of monitoring tuberculosis reporting delays in New York City.

Silin M, Laraque F, Munsiff SS, Crossa A, Harris TG

Journal of public health management and practice : JPHMP.. 2010 16 (5):E09-17. Epub 1900 01 01.

Performance of nucleic acid amplification tests for diagnosis of tuberculosis in a large urban setting.

Laraque F, Griggs A, Slopen M, Munsiff SS

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2009 July 149 (1):46-54. Epub 1900 01 01.

Communicable disease and immigration fears.

Munsiff SS

The virtual mentor : VM.. 2007 December 19 (12):799-805. Epub 12/01/2007.

Evaluation of case management in tuberculosis control: a three-year effort to improve case management practices in New York City.

Udeagu CC, Dorsinville MS, Munsiff SS, Vilnyanskaya Y, Wang I

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2007 October 11 (10):1094-100. Epub 1900 01 01.

Molecular epidemiology of tuberculosis after declining incidence, New York City, 2001-2003.

Driver CR, Kreiswirth B, Macaraig M, Clark C, Munsiff SS, Driscoll J, Zhao B

Epidemiology and infection.. 2007 May 135 (4):634-43. Epub 10/26/2006.

Outcomes of multidrug-resistant tuberculosis treatment in HIV-positive patients in New York City, 1990-1997.

Frieden TR, Munsiff SS, Ahuja SD

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2007 January 11 (1):116. Epub 1900 01 01.

Human immunodeficiency virus counseling, testing, and referral of close contacts to patients with pulmonary tuberculosis: feasibility and costs.

Li J, Marks SM, Driver CR, Diaz FA, Castro AF, de Regner AF, Gibson AE, Dokubo-Okereke K, Munsiff SS,

Journal of public health management and practice : JPHMP.. 2007 13 (3):252-62. Epub 1900 01 01.

Rifapentine for the treatment of pulmonary tuberculosis.

Munsiff SS, Kambili C, Ahuja SD

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2006 December 143 (11):1468-75. Epub 10/24/2006.

Ensuring accountability: the contribution of the cohort review method to tuberculosis control in New York City.

Munsiff SS, Ahuja SD, King L, Udeagu CC, Dorsinville M, Frieden TR, Fujiwara PI

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2006 October 10 (10):1133-9. Epub 1900 01 01.

Moxifloxacin versus ethambutol in the first 2 months of treatment for pulmonary tuberculosis.

Burman WJ, Goldberg S, Johnson JL, Muzanye G, Engle M, Mosher AW, Choudhri S, Daley CL, Munsiff SS, Zhao Z, Vernon A, Chaisson RE

American journal of respiratory and critical care medicine.. 2006 August 1174 (3):331-8. Epub 05/04/2006.

Strain-specific differences in two large Mycobacterium tuberculosis genotype clusters in isolates collected from homeless patients in New York City from 2001 to 2004.

Macaraig M, Agerton T, Driver CR, Munsiff SS, Abdelwahab J, Park J, Kreiswirth B, Driscoll J, Zhao B

Journal of clinical microbiology.. 2006 August 44 (8):2890-6. Epub 1900 01 01.

Which patients' factors predict the rate of growth of Mycobacterium tuberculosis clusters in an urban community?

Driver CR, Macaraig M, McElroy PD, Clark C, Munsiff SS, Kreiswirth B, Driscoll J, Zhao B

American journal of epidemiology.. 2006 July 1164 (1):21-31. Epub 04/26/2006.

Trends in drug-resistant Mycobacterium tuberculosis in New York City, 1991-2003.

Munsiff SS, Li J, Cook SV, Piatek A, Laraque F, Ebrahimzadeh A, Fujiwara PI

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2006 June 1542 (12):1702-10. Epub 05/12/2006.

Public-private collaboration for multidrug-resistant tuberculosis control in New York City.

Munsiff SS, Ahuja SD, Li J, Driver CR

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2006 June 10 (6):639-48. Epub 1900 01 01.

Universal genotyping in tuberculosis control program, New York City, 2001-2003.

Clark CM, Driver CR, Munsiff SS, Driscoll JR, Kreiswirth BN, Zhao B, Ebrahimzadeh A, Salfinger M, Piatek AS, Abdelwahab J

Emerging infectious diseases.. 2006 May 12 (5):719-24. Epub 1900 01 01.

Tuberculosis prevention for non-US-born pregnant women.

Sackoff JE, Pfeiffer MR, Driver CR, Streett LS, Munsiff SS, DeHovitz JA

American journal of obstetrics and gynecology.. 2006 February 194 (2):451-6. Epub 1900 01 01.

Tuberculosis in health care workers during declining tuberculosis incidence in New York State.

Driver CR, Stricof RL, Granville K, Munsiff SS, Savranskaya G, Kearns C, Christie A, Oxtoby M

American journal of infection control.. 2005 November 33 (9):519-26. Epub 1900 01 01.

Risk factors for drug-resistant tuberculosis among non-US-born persons in New York City.

Clark CM, Li J, Driver CR, Munsiff SS

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2005 September 9 (9):964-9. Epub 1900 01 01.

How late after injection can a tuberculin skin test be interpreted?

Munsiff SS

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2005 July 1541 (2):271; author reply 271. Epub 1900 01 01.

Relapse and acquired rifampin resistance in HIV-infected patients with tuberculosis treated with rifampin- or rifabutin-based regimens in New York City, 1997-2000.

Li J, Munsiff SS, Driver CR, Sackoff J

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2005 July 141 (1):83-91. Epub 05/26/2005.

The DOTS strategy for controlling the global tuberculosis epidemic.

Frieden TR, Munsiff SS

Clinics in chest medicine.. 2005 June 26 (2):197-205, v. Epub 1900 01 01.

Patients with drug-resistant tuberculosis who were treated with standardized short-course chemotherapy.

Munsiff SS, Ahuja SD

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2005 May 1540 (10):1549-50. Epub 1900 01 01.

Factors associated with tuberculosis treatment interruption in New York City.

Driver CR, Matus SP, Bayuga S, Winters AI, Munsiff SS

Journal of public health management and practice : JPHMP.. 2005 11 (4):361-8. Epub 1900 01 01.

Use of therapeutic drug monitoring for multidrug-resistant tuberculosis patients.

Li J, Burzynski JN, Lee YA, Berg D, Driver CR, Ridzon R, Munsiff SS

Chest.. 2004 December 126 (6):1770-6. Epub 1900 01 01.

Effectiveness of isoniazid treatment for latent tuberculosis infection among human immunodeficiency virus (HIV)-infected and HIV-uninfected injection drug users in methadone programs.

Scholten JN, Driver CR, Munsiff SS, Kaye K, Rubino MA, Gourevitch MN, Trim C, Amofa J, Seewald R, Highley E, Fujiwara PI

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2003 December 1537 (12):1686-92. Epub 11/17/2003.

Finding contacts of homeless tuberculosis patients in New York City.

Li J, Driver CR, Munsiff SS, Fujiwara PI

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2003 December 17 (12):397-404. Epub 1900 01 01.

Contact investigations in congregate settings, New York City.

Driver CR, Balcewicz-Sablinska MK, Kim Z, Scholten J, Munsiff SS

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2003 December 17 (12):432-438. Epub 1900 01 01.

Finding contacts of homeless tuberculosis patients in New York City.

Li J, Driver CR, Munsiff SS, Fujiwara PI

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2003 December 7 (12 Suppl 3):S397-404. Epub 1900 01 01.

Contact investigations in congregate settings, New York City.

Driver CR, Balcewicz-Sablinska MK, Kim Z, Scholten J, Munsiff SS

Prevalence of tuberculin skin test positivity and conversions among healthcare workers in New York City during 1994 to 2001.

Cook S, Maw KL, Munsiff SS, Fujiwara PI, Frieden TR

Infection control and hospital epidemiology.. 2003 November 24 (11):807-13. Epub 1900 01 01.

Tuberculosis.

Frieden TR, Sterling TR, Munsiff SS, Watt CJ, Dye C

Lancet.. 2003 September 13362 (9387):887-99. Epub 1900 01 01.

Persistence of a highly resistant strain of tuberculosis in New York City during 1990-1999.

Munsiff SS, Nivin B, Sacajiu G, Mathema B, Bifani P, Kreiswirth BN

The Journal of infectious diseases.. 2003 August 1188 (3):356-63. Epub 07/18/2003.

Differential decline in tuberculosis incidence among US- and non-US-born persons in New York City.

Li JH, Driver CR, Munsiff SS, Yip R, Fujiwara PI

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2003 May 7 (5):451-7. Epub 1900 01 01.

Tuberculin testing and risk of tuberculosis infection among New York City schoolchildren.

Gounder CR, Driver CR, Scholten JN, Shen H, Munsiff SS

Pediatrics.. 2003 April 111 (4 Pt 1):e309-15. Epub 1900 01 01.

Management of latent tuberculosis infection in immigrants.

Sterling T, Munsiff SS, Frieden TR

The New England journal of medicine.. 2003 March 27348 (13):1289-92; author reply 1289-92. Epub 1900 01 01.

Molecular epidemiology of multidrug-resistant tuberculosis, New York City, 1995-1997.

Munsiff SS, Bassoff T, Nivin B, Li J, Sharma A, Bifani P, Mathema B, Driscoll J, Kreiswirth BN

Emerging infectious diseases.. 2002 November 8 (11):1230-8. Epub 1900 01 01.

Yield of continued monthly sputum evaluation among tuberculosis patients after culture conversion.

Sundaram V, Fujiwara PI, Driver CR, Osahan SS, Munsiff SS

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.. 2002 March 6 (3):238-45. Epub 1900 01 01.

Targeting tuberculosis testing: the yield of source case investigations for young children with reactive tuberculin skin tests.

Driver CR, Cordova IM, Munsiff SS

Public health reports.. 2002 117 (4):366-72. Epub 1900 01 01.

Relapse in persons treated for drug-susceptible tuberculosis in a population with high coinfection with human immunodeficiency virus in New York City.

Driver CR, Munsiff SS, Li J, Kundamal N, Osahan SS

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2001 November 1533 (10):1762-9. Epub 10/10/2001.

Rising number of tuberculosis cases among Tibetans in New York City.

Lee YA, Munsiff SS, Li J, Driver CR, Mathema B, Kreiswirth BN

Journal of immigrant health. 2001 October 3 (4):173-80. Epub 1900 01 01.

Molecular identification of streptomycin monoresistant Mycobacterium tuberculosis related to multidrug-resistant W strain.

Bifani P, Mathema B, Campo M, Moghazeh S, Nivin B, Shashkina E, Driscoll J, Munsiff SS, Frothingham R, Kreiswirth BN

Emerging infectious diseases.. 2001 7 (5):842-8. Epub 1900 01 01.

Use of spoligotype analysis to detect laboratory cross-contamination.

Nivin B, Driscoll J, Glaser T, Bifani P, Munsiff S

Infection control and hospital epidemiology.. 2000 August 21 (8):525-7. Epub 1900 01 01.

Tuberculosis treatment practices in the era of protease inhibitors: a provider survey.

Sundaram V, Driver CR, Munsiff SS

AIDS.. 1999 January 1413 (1):149-50. Epub 1900 01 01.

A prospective study of tuberculosis and HIV disease progression.

Munsiff SS, Alpert PL, Gourevitch MN, Chang CJ, Klein RS

Journal of acquired immune deficiency syndromes and human

Drug-susceptible tuberculosis.

Munsiff SS, Driver C

The Journal of infectious diseases.. 1998 April 177 (4):1138-9. Epub 1900 01 01.

Rifampin-monoresistant tuberculosis in New York City, 1993-1994.

Munsiff SS, Joseph S, Ebrahimzadeh A, Frieden TR

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1997 December 25 (6):1465-7. Epub 1900 01 01.

Detection of laboratory cross-contamination of Mycobacterium Mycobacteriu cultures.

Nivin B, Kaye K, Munsiff SS

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1997 October 25 (4):943. Epub 1900 01 01.

A prospective study of tuberculosis and human immunodeficiency virus infection: clinical manifestations and factors associated with survival.

Alpert PL, Munsiff SS, Gourevitch MN, Greenberg B, Klein RS

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1997 April 24 (4):661-8. Epub 1900 01 01.

Laboratory errors and the misdiagnosis of tuberculosis.

Kaye K, Nivin B, Munsiff S, Fujiwara PI

JAMA.. 1997 March 19277 (11):882-3. Epub 1900 01 01.

Effect of Mycobacterium tuberculosis on HIV replication. Role of immune activation.

Goletti D, Weissman D, Jackson RW, Graham NM, Vlahov D, Klein RS, Munsiff SS, Ortona L, Cauda R, Fauci AS

The Journal of immunology : official journal of the American Association of Immunologists.. 1996 August 1157 (3):1271-8. Epub 1900 01 01.

Emergence of vancomycin-resistant enterococci in New York City.

Frieden TR, Munsiff SS, Low DE, Willey BM, Williams G, Faur Y, Eisner W, Warren S, Kreiswirth B

Lancet.. 1993 July 10342 (8863):76-9. Epub 1900 01 01.