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Jacob W. Nadler, M.D., Ph.D.

Jacob W. Nadler, M.D., Ph.D.

Anesthesiology and Perioperative Medicine

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
Accepting New Patients


Appointment (585) 275-2141

About Me

Certified Specialties

Anesthesiology - American Board of Anesthesiology

Faculty Appointments

Associate Professor - Department of Anesthesiology and Perioperative Medicine (SMD)


Residency & Fellowship

Fellowship, Duke University School of Medicine. 2013 - 2014

Residency, Anesthesiology, Duke University School of Medicine. 2010 - 2013

Internship, Anesthesiology, Duke University School of Medicine. 2009 - 2010


MD | Washington University School of Medicine. 2009

PHD | Washington University School of Medicine. 2009


Fellow of the American Society of Anesthesiologists. 2023

Meliora Award. 2021

Medical Center Board Quality of Care Committee Special Recognition. 2021

Ronald A. Gabel Award for Teaching Excellence. 2020

Unit-Based Performance Program Award: Greatest Outcome. 2020

ICARE Bronze Star. 2019

Academic Career Enrichment Scholar. 2009 - 2014

James L. O'Leary Prize for Research in Neuroscience. 2007

Chancellor's Undergraduate Research Award. 2001

Phi Beta Kappa. 2001

Barry M. Goldwater Scholarship. 2000

Golden Key National Honor Society. 1999


Journal Articles

Was COVID-19 Associated With Worsening Inequities in Stroke Treatment and Outcomes?

Glance LG, Benesch CG, Joynt Maddox KE, Bender MT, Shang J, Stone PW, Lustik SJ, Nadler JW, Galton C, Dick AW

Journal of the American Heart Association.. 2023 September 26 :e031221. Epub 09/26/2023.

Society of Anesthesia and Sleep Medicine and the Society for Obstetric Anesthesia and Perinatology Consensus Guideline on the Screening, Diagnosis, and Treatment of Obstructive Sleep Apnea in Pregnancy.

Dominguez JE, Cantrell S, Habib AS, Izci-Balserak B, Lockhart E, Louis JM, Miskovic A, Nadler JW, Nagappa M, O'Brien LM, Won C, Bourjeily G

Obstetrics and gynecology.. 2023 July 6 Epub 07/06/2023.

Differences in Perioperative Management of Patients Undergoing Complex Spine Surgery: A Global Perspective.

Blacker SN, Woody N, Abate Shiferaw A, Burbridge M, Bustillo MA, Hazard SW, Heller BJ, Lamperti M, Mejia-Mantilla J, Nadler JW, Rath GP, Robba C, Vincent A, Admasu AK, Awraris M, Lele AV

Journal of neurosurgical anesthesiology.. 2023 May 16 Epub 05/16/2023.

General Anesthetics in CAncer REsection Surgery (GA-CARES) randomized multicenter trial of propofol vs volatile inhalational anesthesia: protocol description.

Bennett-Guerrero E, Romeiser JL, DeMaria S, Nadler JW, Quinn TD, Ponnappan SK, Yang J, Sasson AR

Perioperative medicine.. 2023 January 1112 (1):2. Epub 01/11/2023.

Updates in Prevention of Surgical Site Infection: Comment.

Mundangepfupfu T, Nadler JW

Anesthesiology.. 2023 January 11 Epub 01/11/2023.

"Association of Time Elapsed Since Ischemic Stroke With Risk of Recurrent Stroke in Older Patients Undergoing Elective Nonneurologic, Noncardiac Surgery"

Glance ,L.G.; Benesch, C.G.; Holloway, R.G.; Thirukumaran, C.P.; Nadler, J.W.; Eaton, M.P.; Fleming, F.J.; Dick, A.W.

JAMA. 2022; .

"Perioperative Care of Patients Undergoing Major Complex Spinal Instrumentation Surgery: Clinical Practice Guidelines from the Society for Neuroscience in Anesthesiology and Critical Care."

Blacker, S.N.; Vincent, A.; Burbridge, M.; Bustillo, M.; Hazard, S.W.; Heller, B.; Nadler, J.W.; Sullo, E.; Lele, A.V.

J. Neurosurg. Anes. 2022; 34(3): 257-276.

Sleep Apnea and Fetal Growth Restriction (SAFER) study: protocol for a pragmatic randomised clinical trial of positive airway pressure as an antenatal therapy for fetal growth restriction in maternal obstructive sleep apnoea

Hincker, A; Nadler, J; Karan, S; et al.

BMJ Open. 2021; 11(6): e049120.

Preoperative Screening for Obstructive Sleep Apnea to Improve Long-term Outcomes.

Nadler JW, Karan SB, Glance LG

Anesthesiology.. 2020 August 10 Epub 08/10/2020.

Postoperative "Rescue" Use of Erector Spinae Plane Block After Lumbar Spine Fusion: A Report of 2 Cases

Kianpour, DN; Gundy, JT; Nadler, JW; Lindenmuth, DM.

Local Reg Anesth. 2020; 13: 95-98.

Postoperative "Rescue" Use of Erector Spinae Plane Block After Lumbar Spine Fusion: A Report of 2 Cases.

Kianpour DN, Gundy JT, Nadler JW, Lindenmuth DM

Local and regional anesthesia.. 2020 13 :95-98. Epub 08/13/2020.

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping.

Mahon BZ, Mead JA, Chernoff BL, Sims MH, Garcea FE, Prentiss E, Belkhir R, Haber SJ, Gannon SB, Erickson S, Wright KA, Schmidt MZ, Paulzak A, Milano VC, Paul DA, Foxx K, Tivarus M, Nadler JW, Behr JM, Smith SO, Li YM, Walter K, Pilcher WH

Journal of visualized experiments : JoVE.. 2019 August 12 (150)Epub 08/12/2019.

Can anesthesiologists affect cancer outcomes?

Nadler JW, Quinn TD, Bennett-Guerrero E

Canadian journal of anaesthesia = Journal canadien d'anesthe?sie.. 2019 February 25 Epub 02/25/2019.

Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.

Nadtochiy, SM; Wang, YT; Nehrke, K; Munger, J; Brookes, PS.

Journal of molecular and cellular cardiology. 2018; 121: 155-162.

Pilot prospective study of post-surgery sleep and EEG predictors of post-operative delirium.

Evans JL, Nadler JW, Preud'homme XA, Fang E, Daughtry RL, Chapman JB, Attarian D, Wellman S, Krystal AD

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.. 2017 August 128 (8):1421-1425. Epub 05/17/2017.

A randomised trial of peri-operative positive airway pressure for postoperative delirium in patients at risk for obstructive sleep apnoea after regional anaesthesia with sedation or general anaesthesia for joint arthroplasty.

Nadler JW, Evans JL, Fang E, Preud'Homme XA, Daughtry RL, Chapman JB, Bolognesi MP, Attarian DE, Wellman SS, Krystal AD

Anaesthesia.. 2017 June 72 (6):729-736. Epub 03/02/2017.

The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial.

Berger M, Nadler JW, Friedman A, McDonagh DL, Bennett ER, Cooter M, Qi W, Laskowitz DT, Ponnusamy V, Newman MF, Shaw LM, Warner DS, Mathew JP, James ML,

Journal of Alzheimer's disease : JAD.. 2016 April 1552 (4):1299-310. Epub 1900 01 01.

Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly.

Berger M, Nadler JW, Browndyke J, Terrando N, Ponnusamy V, Cohen HJ, Whitson HE, Mathew JP

Anesthesiology clinics.. 2015 September 33 (3):517-50. Epub 07/16/2015.

Intravenous Acetaminophen Administration in Patients Undergoing Craniotomy- A Retrospective Institutional Study

Hoefnagel, AL.; Lopez, M.; Mitchell, K.; Smith, DI.; Feng, C.; Nadler, JW.

J Anesth Clin Res. 2015; 6(568).

Preventing delirium after cardiothoracic surgery: provocative but preliminary evidence for bispectral index monitoring.

Berger M, Nadler J, Mathew JP

Anesthesia and analgesia.. 2014 April 118 (4):706-7. Epub 1900 01 01.

Anesthetic neuroprotection: antecedents and an appraisal of preclinical and clinical data quality.

Ishida K, Berger M, Nadler J, Warner DS

Current pharmaceutical design.. 2014 20 (36):5751-65. Epub 1900 01 01.

Joint representation of depth from motion parallax and binocular disparity cues in macaque area MT.

Nadler JW, Barbash D, Kim HR, Shimpi S, Angelaki DE, DeAngelis GC

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2013 August 2833 (35):14061-74, 14074a. Epub 1900 01 01.

MT neurons combine visual motion with a smooth eye movement signal to code depth-sign from motion parallax.

Nadler JW, Nawrot M, Angelaki DE, DeAngelis GC

Neuron.. 2009 August 2763 (4):523-32. Epub 1900 01 01.

A neural representation of depth from motion parallax in macaque visual cortex.

Nadler JW, Angelaki DE, DeAngelis GC

Nature.. 2008 April 3452 (7187):642-5. Epub 03/16/2008.

Precision pooling predicts primate perceptual performance.

Nadler JW, Deangelis GC

Nature neuroscience.. 2005 January 8 (1):12-3. Epub 1900 01 01.