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Brenda L. Tesini, M.D.

Brenda L. Tesini, M.D.

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About Me

Brenda L. Tesini, M.D. is an assistant professor of medicine and pediatrics in infectious diseases at the University of Rochester. After completing medical school at the University of Miami, she came to the University of Rochester for a combined internal medicine and pediatrics residency followed by...
Brenda L. Tesini, M.D. is an assistant professor of medicine and pediatrics in infectious diseases at the University of Rochester. After completing medical school at the University of Miami, she came to the University of Rochester for a combined internal medicine and pediatrics residency followed by fellowships in both pediatric and adult infectious diseases. She now serves as the associate hospital epidemiologist for the University of Rochester Medical Center and is an actively practicing adult and pediatric infectious diseases clinician. She is the Rochester site PI for several projects in the CDC’s Emerging Infections Program and participates in other CDC and NIH funded population-based infectious disease surveillance and prevention research activities. She has also been an instructor with New York State Department of Health AIDS Institute’s Clinical Education Initiative since 2017 and engages in community level infection prevention and awareness education. Her current research and clinical interests include the surveillance and prevention of multidrug-resistant organism spread within healthcare and community environments.

Faculty Appointments

Associate Professor - Department of Medicine, Infectious Diseases (SMD)

Associate Professor - Center for Community Health and Prevention - Joint

Associate Professor - Department of Pediatrics, Infectious Diseases (SMD) - Joint

Credentials

Post-doctoral Training & Residency

Fellowship, Infectious Disease, University of Rochester Medical Center. 2016 - 2017

Fellowship, Pediatric Infectious Diseases, University of Rochester Medical Center. 2012 - 2015

Residency, Pediatrics, Internal Medicine, University of Rochester Medical Center. 2009 - 2012

Internship, Pediatrics, Internal Medicine, University of Rochester Medical Center. 2008 - 2009

Education

MD | University of Miami School of Medicine. 2008

Awards

ID Week Trainee Travel Grant. 2016

Caroline Breese Hall Award. 2015 - 2016

Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Infectious Diseases Fellows Program Award. 2014

NIAID/IDSA Infectious Diseases Research Careers Meeting Award. 2014

PIDS/St. Jude Children's Research Hospital Conference Travel Award. 2013

Strong Star Award of Appreciation. 2012

University of Miami Trustee Scholar. 2004 - 2008

Presidential Scolar. 1998 - 2000

Dean's Scholar. 1996 - 2000

Research

I am interested in studying the immune response to respiratory infections in both immunocompromised and immunocompetent hosts. This includes projects related to the prevention of Pneumocystis pneumonia and evaluation of the host response to acute lower respiratory viral infections.

Publications

Journal Articles

Characteristics and Outcomes Among Adults Aged ?60 Years Hospitalized with Laboratory-Confirmed Respiratory Syncytial Virus - RSV-NET, 12 States, July 2022-June 2023.

Havers FP, Whitaker M, Melgar M, Chatwani B, Chai SJ, Alden NB, Meek J, Openo KP, Ryan PA, Kim S, Lynfield R, Shaw YP, Barney G, Tesini BL, Sutton M, Talbot HK, Olsen KP, Patton ME, ,

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.. 2023 October 18 Epub 10/18/2023.

High Influenza Incidence and Disease Severity Among Children and Adolescents Aged <18 Years - United States, 2022-23 Season.

White EB, O'Halloran A, Sundaresan D, Gilmer M, Threlkel R, Colón A, Tastad K, Chai SJ, Alden NB, Yousey-Hindes K, Openo KP, Ryan PA, Kim S, Lynfield R, Spina N, Tesini BL, Martinez M, Schmidt Z, Sutton M, Talbot HK, Hill M, Biggerstaff M, Budd A, Garg S, Reed C, Iuliano AD, Bozio CH

MMWR. Morbidity and mortality weekly report.. 2023 October 1372 (41):1108-1114. Epub 10/13/2023.

Characteristics and Outcomes Among Adults Aged ?60 Years Hospitalized with Laboratory-Confirmed Respiratory Syncytial Virus - RSV-NET, 12 States, July 2022-June 2023.

Havers FP, Whitaker M, Melgar M, Chatwani B, Chai SJ, Alden NB, Meek J, Openo KP, Ryan PA, Kim S, Lynfield R, Shaw YP, Barney G, Tesini BL, Sutton M, Talbot HK, Olsen KP, Patton ME,

MMWR. Morbidity and mortality weekly report.. 2023 October 672 (40):1075-1082. Epub 10/06/2023.

COVID-19-Associated Hospitalizations Among U.S. Adults Aged ?65 Years - COVID-NET, 13 States, January-August 2023.

Taylor CA, Patel K, Patton ME, Reingold A, Kawasaki B, Meek J, Openo K, Ryan PA, Falkowski A, Bye E, Plymesser K, Spina N, Tesini BL, Moran NE, Sutton M, Talbot HK, George A, Havers FP,

MMWR. Morbidity and mortality weekly report.. 2023 October 672 (40):1089-1094. Epub 10/06/2023.

Low Sensitivity of Coding for Culture-Confirmed Candidemia Cases in an Active Surveillance System: United States, 2019-2020.

Benedict K, Gold JAW, Jenkins EN, Roland J, Barter D, Czaja CA, Johnston H, Clogher P, Farley MM, Revis A, Harrison LH, Tourdot L, Davis SS, Phipps EC, Felsen CB, Tesini BL, Escutia G, Pierce R, Zhang A, Schaffner W, Lyman M

Open forum infectious diseases.. 2022 September 9 (9):ofac461. Epub 09/07/2022.

Reduction of surgical site infections in pediatric patients with complicated appendicitis: Utilization of antibiotic stewardship principles and quality improvement methodology.

Wakeman D, Livingston MH, Levatino E, Juviler P, Gleason C, Tesini B, Wilson NA, Pegoli W, Arca MJ

Journal of pediatric surgery.. 2021 September 21 Epub 09/21/2021.

The landscape of candidemia during the COVID-19 pandemic.

Seagle EE, Jackson BR, Lockhart SR, Georgacopoulos O, Nunnally NS, Roland J, Barter DM, Johnston HL, Czaja CA, Kayalioglu H, Clogher P, Revis A, Farley MM, Harrison LH, Davis SS, Phipps EC, Tesini BL, Schaffner W, Markus TM, Lyman MM

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2021 June 18 Epub 06/18/2021.

Treatment Practices for Adults with Candidemia at Nine Active Surveillance Sites - United States, 2017-2018.

Gold JAW, Seagle EE, Nadle J, Barter DM, Czaja CA, Johnston H, Farley MM, Thomas S, Harrison LH, Fischer J, Pattee B, Mody RK, Phipps EC, Shrum Davis S, Tesini BL, Zhang AY, Markus TM, Schaffner W, Lockhart SR, Vallabhaneni S, Jackson BR, Lyman M

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2021 June 3 Epub 06/03/2021.

Burden of Candidemia in the United States, 2017.

Tsay SV, Mu Y, Williams S, Epson E, Nadle J, Bamberg WM, Barter DM, Johnston HL, Farley MM, Harb S, Thomas S, Bonner LA, Harrison LH, Hollick R, Marceaux K, Mody RK, Pattee B, Shrum Davis S, Phipps EC, Tesini BL, Gellert AB, Zhang AY, Schaffner W, Hillis S, Ndi D, Graber CR, Jackson BR, Chiller T, Magill S, Vallabhaneni S

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2020 February 28 Epub 02/28/2020.

The Changing Epidemiology of Candidemia in the United States: Injection Drug Use as an Increasingly Common Risk Factor - Active Surveillance in Selected Sites, United States, 2014-17.

Zhang AY, Shrum S, Williams S, Petnic S, Nadle J, Johnston H, Barter D, VonBank B, Bonner L, Hollick R, Marceaux K, Harrison L, Schaffner W, Tesini BL, Farley MM, Pierce RA, Phipps E, Mody RK, Chiller TM, Jackson BR, Vallabhaneni S

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2019 November 2 Epub 11/02/2019.

Next-Generation-Sequencing-Based Hospital Outbreak Investigation Yields Insight into Klebsiella aerogenes Population Structure and Determinants of Carbapenem Resistance and Pathogenicity.

Malek A, McGlynn K, Taffner S, Fine L, Tesini B, Wang J, Mostafa H, Petry S, Perkins A, Graman P, Hardy D, Pecora N

Antimicrobial agents and chemotherapy.. 2019 June 63 (6)Epub 05/24/2019.

Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus.

Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, Ahmed R, Treanor JJ, Martinez-Sobrido L, Golding H, Khurana S, Zand MS, Topham DJ, Sangster MY

Journal of virology.. 2019 April 1593 (8)Epub 04/03/2019.

Immunization with Pneumocystis Cross-Reactive Antigen 1 (Pca1) Protects Mice against Pneumocystis Pneumonia and Generates Antibody to Pneumocystis jirovecii.

Tesini BL, Wright TW, Malone JE, Haidaris CG, Harber M, Sant AJ, Nayak JL, Gigliotti F

Infection and immunity.. 2017 April 85 (4)Epub 03/23/2017.

Development of a Global Respiratory Severity Score for Respiratory Syncytial Virus Infection in Infants.

Caserta MT, Qiu X, Tesini B, Wang L, Murphy A, Corbett A, Falsey AR, Holden-Wiltse J, Walsh EE

The Journal of infectious diseases.. 2017 March 1215 (5):750-756. Epub 1900 01 01.

The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ

Scientific reports.. 2016 September 236 :33994. Epub 09/23/2016.

Clinical impact of primary infection with roseoloviruses.

Tesini BL, Epstein LG, Caserta MT

Current opinion in virology.. 2014 December 9 :91-6. Epub 10/14/2014.

Resilience to bacterial infection: difference between species could be due to proteins in serum.

Warren HS, Fitting C, Hoff E, Adib-Conquy M, Beasley-Topliffe L, Tesini B, Liang X, Valentine C, Hellman J, Hayden D, Cavaillon JM

The Journal of infectious diseases.. 2010 January 15201 (2):223-32. Epub 1900 01 01.

Bacterial peptidoglycan-associated lipoprotein: a naturally occurring toll-like receptor 2 agonist that is shed into serum and has synergy with lipopolysaccharide.

Liang MD, Bagchi A, Warren HS, Tehan MM, Trigilio JA, Beasley-Topliffe LK, Tesini BL, Lazzaroni JC, Fenton MJ, Hellman J

The Journal of infectious diseases.. 2005 March 15191 (6):939-48. Epub 02/08/2005.

Books

Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases (2020)

Chapter: Acute Laryngitis

Authors: Caserta MT and Tesini BL

Publisher: Elsevier 2020

Nelson Textbook of Pediatrics (2020)

Chapter: Roseola (Human Herpesvirus 6 and 7)

Authors: Tesini BL and Caserta MT

Publisher: Elsevier 2020

Nelson Textbook of Pediatrics (2020)

Chapter: Human Herpesvirus 8

Authors: Tesini BL and Caserta MT

Publisher: Elsevier 2020

Merck Manual Professional Edition (2019)

Chapter: Pox Viruses

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2019

Merck Manual Professional Edition (2018)

Chapter: Enteroviruses

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2018

Merck Manual Professional Edition (2018)

Chapter: Miscellaneous Viral Infections in Infants and Children

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2018

Merck Manual Professional Edition (2018)

Chapter: Respiratory Viruses

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2018

Merck Manual Consumer Edition (2018)

Chapter: Viral Infections in Infants and Children

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2018

Merck Manual Consumer Edition (2018)

Chapter: Infections in Newborns

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2018

Merck Manual Consumer Edition (2018)

Chapter: Enteroviruses

Authors: Tesini BL

Publisher: Merck, Sharp & Dohme 2018

). Infectious Diseases of Concern to Captive and Free Ranging Animals in North America (2013)

Chapter: Pneumocystosis

Authors: Hoy Z and Tesini B

Publisher: American Association of Zoo Veterinarians 2013

Locations