Brea C. Lipe, M.D.
I believe that it's important to know my patients as individuals to understand the situational circumstance and personality that drives their treatment goals. Multiple myeloma is a lifelong journey and a strong partnership with my patients is essential to achieving the best quality of care. I have a strong interest in clinical research and like to offer my patients a variety of clinical trial options and treatments based on the most recent data. I have a dedicated support team, so that we can offer patients a team with real myeloma-specific expertise.
In my research laboratory, I am particularly interested in understanding the mechanisms that allow multiple myeloma to develop. I have created a system that lets us mimic in a laboratory, the growth of cancer cells that become multiple myeloma. By studying disease progression, my ultimate goal is to develop therapies to prevent multiple myeloma.
Outside of work, I love to grow things -- flowers, vegetables, orchids, animals, children. I have gotten some of my best gardening tips from my patients.
Conditions I treat:
- Multiple myeloma
- Other plasma cell disorders
Professor - Department of Medicine, Hematology/Oncology (SMD)
Residency & Fellowship
Fellowship, Hematology & Oncology, Dartmouth-Hitchcock Medical Center. 2008 - 2011
Residency, Internal Medicine, Dartmouth-Hitchcock Medical Center. 2006 - 2008
Internship, Internal Medicine, Dartmouth-Hitchcock Medical Center. 2005 - 2006
MD | Albany Medical College. 2005
Leadership Academy. 2017
Department of Internal Medicine OSARM Faculty Incubator Scholar. 2011
Clinical Research Training Institute Clinical Scholar for ASH. 2011
Award for Excellence in Teaching. 2009
Award for Excellence in Teaching. 2007
Frank C. Knievel Scholarship Award. 2001 - 2005
First Generation Diversity Scholarship. 1996 - 2001
Lead Researcher: Brea C Lipe
This phase III trial compares three-drug induction regimens followed by double-or single-drug maintenance therapy for the treatment of newly diagnosed multiple myeloma in patients who are not receiving a stem cell transplant and are considered frail ...
Lead Researcher: Brea C Lipe
The purpose of this study is to evaluate the efficacy and safety of talquetamab in participants with relapsed or refractory multiple myeloma at the recommended Phase 2 dose(s) (RP2Ds) (Part 3).
Lead Researcher: Brea C Lipe
The purpose of this study is to collect clinical data along with bone marrow aspirate samples to see if there is a way to determine which patients are more or less likely to experience disease progression. This study will involve identifying differe...
Keren DF, Bocsi G, Billman BL, Etzell J, Faix JD, Kumar S, Lipe B, McCudden C, Montgomery R, Murray DL, Rai AJ, Redondo TC, Souter L, Ventura CB, Ansari MQ
Archives of pathology & laboratory medicine.. 2021 August 4 Epub 08/04/2021.
Sun S, Tao J, Sedghizadeh PP, Cherian P, Junka AF, Sodagar E, Xing L, Boeckman RK, Srinivasan V, Yao Z, Boyce BF, Lipe B, Neighbors JD, Russell G, McKenna CE, Ebetino FH
British journal of pharmacology.. 2020 September 2 Epub 09/02/2020.
Grant SJ, Lipe B
Clinical lymphoma, myeloma & leukemia.. 2020 September 20 Suppl 1 :S76-S80. Epub 1900 01 01.
Medpage Today. 2020; .
Gasparetto, C; Lentzsch, S; Schiller, G; Callander, N; Tuchman, S; Chen, C; White, D; Kotb, R; Sutherland, H; Sebag, M; Baljevic, M; Bensinger, W; LeBlanc, R; Venner, C; Bahlis, N; Rossi, A; Biran, N; Sheehan, H; Saint-Martin, J; Van Domelen, D; Kai, K; Shah, J; Shacham, S; Kauffman, M; Lipe, B.
eJHaem. 2020; .
Nathwani N, Kurtin SE, Lipe B, Mohile SG, Catamero DD, Wujcik D, Birchard K, Davis A, Dudley W, Stricker CT, Wildes TM
Journal of oncology practice. 2019 November 25 :JOP1900208. Epub 11/25/2019.
Lipe B, Divine C, Abhyankar S, Singh AK, Ganguly S, Lin TL, Baran A, Cantilena AR, Bhatti S, Shune L, Abdelhakim H, McGuirk J, Allin D, Aljitawi OS
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.. 2019 September 25 (9):1713-1719. Epub 06/03/2019.
Lipe B, Passero FC, Gleber C, Portuguese AJ
Leukemia research.. 2019 July 2985 :106195. Epub 07/29/2019.
Hillengass J, Usmani S, Rajkumar SV, Durie BGM, Mateos MV, Lonial S, Joao C, Anderson KC, García-Sanz R, Riva E, Du J, van de Donk N, Berdeja JG, Terpos E, Zamagni E, Kyle RA, San Miguel J, Goldschmidt H, Giralt S, Kumar S, Raje N, Ludwig H, Ocio E, Schots R, Einsele H, Schjesvold F, Chen WM, Abildgaard N, Lipe BC, Dytfeld D, Wirk BM, Drake M, Cavo M, Lahuerta JJ, Lentzsch S
The Lancet. Oncology.. 2019 June 20 (6):e302-e312. Epub 1900 01 01.
Li D, Chiu G, Lipe B, Hopkins RA, Lillis J, Ashton JM, Paul S, Aljitawi OS
Blood advances.. 2019 April 93 (7):1011-1026. Epub 1900 01 01.
Mikhael J, Ismaila N, Cheung MC, Costello C, Dhodapkar MV, Kumar S, Lacy M, Lipe B, Little RF, Nikonova A, Omel J, Peswani N, Prica A, Raje N, Seth R, Vesole DH, Walker I, Whitley A, Wildes TM, Wong SW, Martin T
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2019 April 1 :JCO1802096. Epub 04/01/2019.
Hsu CM, Bennett JM, Lipe B
Clinical lymphoma, myeloma & leukemia.. 2019 January 19 (1):e29-e32. Epub 09/05/2018.
Baker HA, Brown AR, Mahnken JD, Shireman TI, Webb CE, Lipe BC
Cancer medicine. 2019 January 8 (1):455-462. Epub 12/25/2018.
Paul B, Lipe B, Ocio EM, Usmani SZ
American Society of Clinical Oncology educational book. 2019 January 39 :e176-e186. Epub 05/17/2019.
Induction Therapy for Newly Diagnosed Multiple Myeloma.
Paul, B; Lipe, B; Ocio, EM; Usmani, SZ.
Am Soc Clin Oncol Educ Book. 2019; 39: e176-e186.
Portuguese AJ, Lipe B
Blood advances.. 2018 December 112 (23):3443-3446. Epub 1900 01 01.
Li D, Lin TL, Lipe B, Hopkins RA, Shinogle H, Aljitawi OS
Leukemia research.. 2018 September 72 :105-112. Epub 08/16/2018.
Lipe B, Kambhampati S, Veldhuizen PV, Yacoub A, Aljitawi O, Mikhael J
Blood cancer journal.. 2017 December 147 (12):646. Epub 12/14/2017.
Howard C, Lipe B
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.. 2017 April 28 (3):267-268. Epub 1900 01 01.
Aljitawi OS, Paul S, Ganguly A, Lin TL, Ganguly S, Vielhauer G, Capitano ML, Cantilena A, Lipe B, Mahnken JD, Wise A, Berry A, Singh AK, Shune L, Lominska C, Abhyankar S, Allin D, Laughlin M, McGuirk JP, Broxmeyer HE
Blood.. 2016 December 22128 (25):3000-3010. Epub 10/19/2016.
Lipe B, Vukas R, Mikhael J
Blood cancer journal.. 2016 October 216 (10):e485. Epub 10/21/2016.
Gupta N, Hanley MJ, Harvey RD, Badros A, Lipe B, Kukreti V, Berdeja J, Yang H, Hui AM, Qian M, Zhang X, Venkatakrishnan K, Chari A
British journal of haematology.. 2016 September 174 (5):748-59. Epub 05/16/2016.
Palumbo A, Chanan-Khan A, Weisel K, Nooka AK, Masszi T, Beksac M, Spicka I, Hungria V, Munder M, Mateos MV, Mark TM, Qi M, Schecter J, Amin H, Qin X, Deraedt W, Ahmadi T, Spencer A, Sonneveld P,
The New England journal of medicine.. 2016 August 25375 (8):754-66. Epub 1900 01 01.
Lipe, B; Drurie, B.
Pocket Guide for American Society of Hematology. 2016; .
Usmani SZ, Sexton R, Ailawadhi S, Shah JJ, Valent J, Rosenzweig M, Lipe B, Zonder JA, Fredette S, Durie B, Hoering A, Bartlett B, Orlowski RZ
Blood cancer journal.. 2015 August 75 :e334. Epub 08/07/2015.
Howard CR, Lin TL, Cunningham MT, Lipe BC
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.. 2014 September 25 (6):631-3. Epub 1900 01 01.
Toward personalized medicine in acute myelogenous leukemia.
Lin, TL; Lipe, BC.
Personalized Medicine. 2013; 10(6): 427-430.
Lipe BC, Lansigan F, Gui J, Meehan K
Clinical advances in hematology & oncology : H&O.. 2012 January 10 (1):28-32. Epub 1900 01 01.
Lipe BC, Cogbill E, Hill J, Meehan K
Clinical advances in hematology & oncology : H&O.. 2011 December 9 (12):948-51. Epub 1900 01 01.
Lipe B, Ornstein DL
Circulation.. 2011 October 4124 (14):e365-8. Epub 1900 01 01.
Lipe BC, Dumas MA, Ornstein DL
Hematology/oncology clinics of North America.. 2011 April 25 (2):335-58, viii. Epub 1900 01 01.
Kuemmerle NB, Rysman E, Lombardo PS, Flanagan AJ, Lipe BC, Wells WA, Pettus JR, Froehlich HM, Memoli VA, Morganelli PM, Swinnen JV, Timmerman LA, Chaychi L, Fricano CJ, Eisenberg BL, Coleman WB, Kinlaw WB
Molecular cancer therapeutics.. 2011 March 10 (3):427-36. Epub 01/31/2011.
The Journal of the American Osteopathic Association.. 1987 February 87 (2 Suppl):175-80. Epub 1900 01 01.