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Xiaoyan Liao, M.D., Ph.D.

Xiaoyan Liao, M.D., Ph.D.

About Me

Faculty Appointments

Associate Professor - Department of Pathology and Laboratory Medicine (SMD)


Post-doctoral Training & Residency

Fellowship, Gastrointestinal and Liver Pathology, Mount Sinai Medical Center. 2017 - 2018

Residency, Pathology, Anatomic Pathology & Clinical Pathology, University of California Medical Center San Diego. 2013 - 2017


PHD | UCLA-University of California Los Angeles. 2007

MSMD | Peking University (China). 2002

MD | Peking University Health Science Center. 1999


Best Abstract Award, CAPA/USCAP 2023.

Epstein Award for Excellence in Research, UCSD Pathology Residency Program, 2017.

Best Abstract Award, CAPA/USCAP 2018.


Journal Articles

High risk features in colorectal adenomatous polyps: A multi-institutional study.

Lee M, Ko HM, Kudose S, Remotti H, Choi WT, Salomao MA, Zhao L, Isidro RA, Liao X, Ettel MG, Chen IY, Liu X, Pai R, Alpert L, Setia N, Wu E, Henn P, Westbrook L, Lagana SM

Annals of diagnostic pathology.. 2024 May 872 :152323. Epub 05/08/2024.

Nonconventional Dysplasia is Frequently Associated With Goblet Cell Deficient and Serrated Variants of Colonic Adenocarcinoma in Inflammatory Bowel Disease.

Xiao A, Yozu M, K?vári BP, Yassan L, Liao X, Salomao M, Westerhoff M, Sejben A, Lauwers GY, Choi WT

The American journal of surgical pathology.. 2024 March 27 Epub 03/27/2024.

Prognostic implications of tumor histology and microenvironment in surgically resected intrahepatic cholangiocarcinoma: a single institutional experience.

Chen IY, Dunne RF, Liao X

Virchows Archiv : an international journal of pathology.. 2024 March 19 Epub 03/19/2024.

Histology Shift in Esophageal Cancer Between Biopsies and Resections After Neoadjuvant Therapy: A Pilot Study.

Hou T, Yang Z, Zhang Q, Zhang X, Liao X, Lin J

International journal of surgical pathology.. 2023 October 30 :10668969231208029. Epub 10/30/2023.

Post-Infantile Giant Cell Hepatitis in Native and Allograft Livers: A Multi-Institutional Clinicopathologic Study of 70 Cases.

Jiao J, Chezar K, Zhang X, Wang D, Cao W, Bindu C, Chen W, Neto AG, Henn P, Riahi I, Wang HL, Papke DJ, Zhao L, Xue Y, Liao X, Zhang X

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2023 August 4 :100298. Epub 08/04/2023.

Clinicopathologic and Molecular Characterization of Anorectal Neuroendocrine Carcinomas Reveals Human Papillomavirus, p53 and c-Myc as Alternative Mechanisms of Carcinogenesis.

Cox AJ, Crowe WE, Yang Q, Zhang B, Oltvai ZN, Liao X

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 2023 July 28 :100295. Epub 07/28/2023.

Non-conventional dysplasia is frequently associated with low-grade tubuloglandular and mucinous adenocarcinomas in inflammatory bowel disease.

Akarca FG, Yozu M, Alpert L, K?vári BP, Zhao L, Salomao M, Liao X, Westerhoff M, Lauwers GY, Choi WT

Histopathology.. 2023 April 13 Epub 04/13/2023.

Primary and Secondary Angiosarcomas of the Liver: A Multi-institutional Study of 32 Cases.

Liao X, Lai J, Lin J, Zhang D

Human pathology.. 2023 April 11 Epub 04/11/2023.

Paget cells of the esophagus: A clinicopathologic and immunohistochemical study of 10 cases.

Liu X, Zhang D, Liao X

Pathology, research and practice.. 2023 January 24242 :154345. Epub 01/24/2023.

Synchronous triple thyroid neoplasms with unique molecular alterations: A rare case report

Xiaoyan Liao, Zoltán N. Oltvai, Dongwei Zhang,.

Human Pathology Reports. 2023; 33(300709).

Clinicopathologic characterization and assessment of prognostic factors for intraabdominal solitary fibrous tumors involving the gastrointestinal tract and liver.

Liu X, Beltejar MJ, Liao X

Virchows Archiv : an international journal of pathology.. 2022 August 17 Epub 08/17/2022.

Pan-TRK Immunohistochemistry and NTRK Gene Fusions in Primary Carcinomas of the Liver.

Zhang D, Liao X

Applied immunohistochemistry & molecular morphology : AIMM. 2022 May 10 Epub 05/10/2022.

Tumor Size, Not Small Vessel Invasion, Predicts Survival in Patients With Hepatocellular Carcinoma.

Zhang D, Love T, Hao Y, Liu BL, Thung S, Fiel MI, Whitney-Miller CL, Liao X

American journal of clinical pathology.. 2022 February 10 Epub 02/10/2022.

HHLA2 Immune Checkpoint Is a Novel Prognostic Predictor in Hepatocellular Carcinoma.

Liao X, Zhang D

American journal of clinical pathology.. 2022 January 27 Epub 01/27/2022.

Inflammatory pseudotumor mimicking chronic pulmonary embolism or pulmonary artery sarcoma: Report of five cases.

Liao X, Bojanowski CM, Yen A, Kerr KM, Dumouchel J, Auger WR, Madani MM, Pretorius V, Wang HY, Yi ES, Lin GY

Pulmonary circulation.. 2022 January 12 (1):e12004. Epub 12/29/2021.

Development of a Scoring System to Differentiate Amiodarone-Induced Liver Injury From Alcoholic Steatohepatitis.

González IA, Fuller LD, Zhang X, Papke DJ, Zhao L, Zhang D, Liao X, Liu X, Fiel MI, Zhang X

American journal of clinical pathology.. 2021 October 1 Epub 10/01/2021.

Poorly differentiated neuroendocrine carcinomas of the gastrointestinal tract: A single-institute study of 43 cases.

Chen I, Zhang D, Velez M, Kovar S, Liao X

Pathology, research and practice.. 2021 September 11226 :153614. Epub 09/11/2021.

Congenital hepatic fibrosis and its mimics: a clinicopathologic study of 19 cases at a single institution.

Chen IY, Whitney-Miller CL, Liao X

Diagnostic pathology.. 2021 August 3016 (1):81. Epub 08/30/2021.

Hypermucinous, Goblet Cell Deficient, and Crypt Cell Dysplasias in Inflammatory Bowel Disease are Often Associated with Flat/Invisible Endoscopic Appearance and Advanced Neoplasia on Follow-Up.

Choi WT, Salomao M, Zhao L, Alpert L, Setia N, Liao X, Drage MG, Westerhoff M, Cheng J, Lauwers GY, Ko HM

Journal of Crohn's & colitis.. 2021 July 7 Epub 07/07/2021.

Primary Colonic Medullary Carcinoma With Exclusive Squamous Differentiation.

Chen IY, Findeis-Hosey JJ, Cannon L, Liao X

Anticancer research.. 2021 July 41 (7):3567-3572. Epub 1900 01 01.

Small Intestinal Adenocarcinomas Arising in Enteritis Cystica Profunda With Metaplasia: A Report of 2 Cases.

Zhang D, Chen I, Liao X

Applied immunohistochemistry & molecular morphology : AIMM. 2021 June 16 Epub 06/16/2021.

Interobserver agreement and the impact of mentorship on the diagnosis of inflammatory bowel disease-associated dysplasia among subspecialist gastrointestinal pathologists.

Alpert L, Setia N, Ko HM, Lagana SM, Pittman ME, Johncilla M, Drage MG, Zhao L, Salomao MA, Liao X, Choi WT, Jenkins SM, Hart J, Harpaz N, Voltaggio L, Lauwers GY, Odze R, Remotti H, Smyrk TC, Graham RP

Virchows Archiv : an international journal of pathology.. 2021 January 3 Epub 01/03/2021.

Well-differentiated Spindle Cell Liposarcoma of the Larynx: A Rare Case Report and Review of Literature.

Liao X, Fulmer S, Zhang D

In vivo.. 2021 35 (5):2779-2783. Epub 1900 01 01.

Squamous Cell Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: Unusual Entity and Diagnostic Pitfalls.

Liu X, Liao X, Zhang D

Cancer diagnosis & prognosis.. 2021 1 (4):279-283. Epub 07/03/2021.

An Unusual Case of Human Papillomavirus-Related Anorectal Adenocarcinoma With Progression to Perianal Paget's Disease.

Katerji R, Liao X, Huber A, Zhang D

International journal of surgical pathology.. 2020 December 24 :1066896920982367. Epub 12/24/2020.

Hepatic involvement by T-cell neoplasms: a clinicopathologic study of 40 cases.

Li P, Zhang D, Zhou J, Li P, Shen Y, Pan Z, Evans AG, Liao X

Human pathology.. 2020 September 30 Epub 09/30/2020.

Malignant tumors in hernia sac: Clinicopathological and immunohistochemical studies of 21 cases at a single institution.

Zhang D, Yang Q, Katerji R, Drage MG, Huber A, Liao X

Pathology international.. 2020 September 17 Epub 09/17/2020.

Mixed adenoneuroendocrine carcinoma of the gallbladder, amphicrine type: Case report and review of literature.

Zhang D, Li P, Szankasi P, Liao X

Pathology, research and practice.. 2020 July 216 (7):152997. Epub 05/04/2020.

The 8th Edition American Joint Committee on Cancer Staging for Hepato-pancreato-biliary Cancer: A Review and Update.

Liao X, Zhang D

Archives of pathology & laboratory medicine.. 2020 March 30 Epub 03/30/2020.

Perianal Paget's disease: a clinicopathological and immunohistochemical study of 13 cases.

Liao X, Liu X, Fan X, Lai J, Zhang D

Diagnostic pathology.. 2020 March 2415 (1):29. Epub 03/24/2020.

Glomus Tumor of the Colon: A Rare Case Report and Review of Literature.

Chen IY, Fazili BG, Liao X

International journal of surgical pathology.. 2020 March 18 :1066896920912826. Epub 03/18/2020.

Collision Tumor of a Squamous Cell Carcinoma and Adenoid Cystic Carcinoma in Mobile Tongue

Liao X, Fontanarosa JB, Zhang D.

Journal of Clinical Research and Medicine. 2020; 3(1).

Impact of EUS-guided microforceps biopsy and needle-based confocal laser endomicroscopy on the diagnostic yield and clinical management of pancreatic cystic lesions.

DiMaio CJ, Nagula S, Kumta NA, Szporn AH, Liao X, Zhu H, Cheesman AR

Gastrointestinal endoscopy.. 2019 December 24 Epub 12/24/2019.

Primary Dedifferentiated Amelanotic Anorectal Melanoma: Report of a Rare Case.

Liao X, Dunn AL, Israel AK, Bell PD

International journal of surgical pathology.. 2019 December 27 (8):923-928. Epub 06/24/2019.

Inflammatory bowel disease- and Barrett's esophagus-associated neoplasia: the old, the new, and the persistent struggles.

Liu XL, Xu JH, Liao XY, Zhang Q, Karamchandani DM

Gastroenterology report.. 2019 December 7 (6):379-395. Epub 08/13/2019.

Hepatocellular adenoma(s) arising in nodular regenerative hyperplasia in a patient with systemic lupus erythematosus.

Liao X, Liu X, Zhang D, Levstik M, Weiss S, Thung S, Bell PD

Pathology, research and practice.. 2019 November 28 :152770. Epub 11/28/2019.

Clinicopathologic features of Buschke-Löwenstein tumor: a multi-institutional analysis of 38 cases.

Liu X, Lai J, Liao X, Alpert L, Zhang X, Westerhoff M, Lin J, Zaleski M, Karamchandani DM, Allende DS, Lee H, Umrau K, Feely M, Gonzalez RS, Zhang D

Virchows Archiv : an international journal of pathology.. 2019 November 15 Epub 11/15/2019.

Mutation Profile of High-Grade Appendiceal Mucinous Neoplasm.

Liao X, Vavinskaya V, Sun K, Hao Y, Li X, Valasek M, Xu R, Polydorides AD, Houldsworth J, Harpaz N

Histopathology.. 2019 September 6 Epub 09/06/2019.

Clinicopathological and Molecular Characterization of Crohn's Disease-Associated Small Bowel Adenocarcinomas.

Polydorides AD, Harpaz N, Houldsworth J, McBride R, Li G, Liao X

Journal of Crohn's & colitis.. 2019 August 7 Epub 08/07/2019.

Warthin-like Mucoepidermoid Carcinoma of the Parotid Gland: Unusual Morphology and Diagnostic Pitfalls.

Lai J, Islam MN, Liu X, VAN Dyke DL, Meyer RG, Tang Y, Liao X, Zhang D

Anticancer research.. 2019 June 39 (6):3213-3217. Epub 1900 01 01.

Polypoid Undifferentiated Carcinoma With Osteoclast-like Giant Cells Arising in the Distal Common Bile Duct: A Rare Case Report.

Zhu H, Harpaz N, Luo J, Houldsworth J, Liao X

Anticancer research.. 2019 January 39 (1):437-441. Epub 1900 01 01.

Clinicopathological characterization of SMAD4-mutated intestinal adenocarcinomas: A case-control study.

Liao X, Hao Y, Zhang X, Ward S, Houldsworth J, Polydorides AD, Harpaz N

PloS one.. 2019 14 (2):e0212142. Epub 02/07/2019.

Sarcomatoid Renal Cell Carcinoma With Unusual Metastasis to the Small Intestine Manifesting as Perforated Appendicitis.

Zhang D, Abu-Farsakh SH, Liao X

In vivo.. 2019 33 (6):2225-2228. Epub 1900 01 01.

Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1.

Zolekar A, Lin VJT, Mishra NM, Ho YY, Hayatshahi HS, Parab A, Sampat R, Liao X, Hoffmann P, Liu J, Emmitte KA, Wang YC

British journal of cancer.. 2018 December 119 (12):1538-1551. Epub 11/02/2018.

A Single Institutional Experience With the Paris System for Reporting Urinary Cytology: Correlation of Cytology and Histology in 194 Cases.

Zare S, Mirsadraei L, Reisian N, Liao X, Roma A, Shabaik A, Hasteh F

American journal of clinical pathology.. 2018 July 3150 (2):162-167. Epub 1900 01 01.

Immunostaining Detection of Cytomegalovirus in Gastrointestinal Biopsies: Clinicopathological Correlation at a Large Academic Health System.

Liao X, Reed SL, Lin GY

Gastroenterology research.. 2016 December 9 (6):92-98. Epub 12/23/2016.

Thoracic Extramedullary Hematopoiesis Mimicking Metastatic Cancer.

Ha D, Liao X, Wang HY, Jamieson C, Magaña M, Makani S

Journal of bronchology & interventional pulmonology.. 2016 October 23 (4):343-346. Epub 1900 01 01.

Erdheim-Chester disease with novel gene mutations discovered as an incidental finding in explanted liver of a patient with hepatitis C cirrhosis: A case report and literature review.

Liao X, Thorson JA, Hughes T, Nguyen JC, Wang HY, Lin GY

Pathology, research and practice.. 2016 September 212 (9):849-54. Epub 07/05/2016.

Discontinuous unilateral involvement of 12 part core biopsies by adenocarcinoma predicts bilateral involvement of subsequent radical prostatectomy.

Lowenthal BM, Liao X, Wen F, Bagherzadeh N, Mahooti S

Pathology international.. 2016 August 66 (8):438-43. Epub 07/20/2016.

A Rare Case of Exclusively Oncocytic Mucoepidermoid Carcinoma with MAML2 Translocation.

Liao X, Haghighi P, Coffey CS, Xu X

Rare tumors.. 2016 June 288 (2):6166. Epub 06/28/2016.

Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate.

Lou CH, Dumdie J, Goetz A, Shum EY, Brafman D, Liao X, Mora-Castilla S, Ramaiah M, Cook-Andersen H, Laurent L, Wilkinson MF

Stem cell reports.. 2016 June 146 (6):844-857. Epub 1900 01 01.

Maternal obesity and sex-specific differences in placental pathology.

Leon-Garcia SM, Roeder HA, Nelson KK, Liao X, Pizzo DP, Laurent LC, Parast MM, LaCoursiere DY

Placenta.. 2016 February 38 :33-40. Epub 12/15/2015.

p16INK4A expression is frequently increased in periorbital and ocular squamous lesions.

Kobalka PJ, Abboud JP, Liao X, Jones K, Lee BW, Korn BS, Kikkawa DO, Lin JH

Diagnostic pathology.. 2015 September 2410 :175. Epub 09/24/2015.

Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions.

Liao X, Xue H, Wang YC, Nazor KL, Guo S, Trivedi N, Peterson SE, Liu Y, Loring JF, Laurent LC

Journal of cell science.. 2013 September 1126 (Pt 17):3848-61. Epub 06/26/2013.

Melanocytes derived from transgene-free human induced pluripotent stem cells.

Jones JC, Sabatini K, Liao X, Tran HT, Lynch CL, Morey RE, Glenn-Pratola V, Boscolo FS, Yang Q, Parast MM, Liu Y, Peterson SE, Laurent LC, Loring JF, Wang YC

The Journal of investigative dermatology.. 2013 August 133 (8):2104-8. Epub 03/20/2013.

Genetic and pathologic aspects of retinoic acid-induced limb malformations in the mouse.

Lee GS, Liao X, Shimizu H, Collins MD

Birth defects research. Part A, Clinical and molecular teratology.. 2010 October 88 (10):863-82. Epub 1900 01 01.

All-trans retinoic acid-induced ectopic limb and caudal structures: murine strain sensitivities and pathogenesis.

Liao X, Collins MD

Developmental dynamics : an official publication of the American Association of Anatomists.. 2008 June 237 (6):1553-64. Epub 1900 01 01.

FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice.

Martin LJ, Chen H, Liao X, Allayee H, Shih DM, Lee GS, Hovland DN, Robbins WA, Carnes K, Hess RA, Lusis AJ, Collins MD

Toxicological sciences : an official journal of the Society of Toxicology.. 2007 December 100 (2):474-85. Epub 09/04/2007.

Comparative molecular pathology of cadmium- and all-trans-retinoic acid-induced postaxial forelimb ectrodactyly.

Liao X, Lee GS, Shimizu H, Collins MD

Toxicology and applied pharmacology.. 2007 November 15225 (1):47-60. Epub 06/21/2007.

Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 mice.

Lee GS, Liao X, Cantor RM, Collins MD

Birth defects research. Part A, Clinical and molecular teratology.. 2006 January 76 (1):19-28. Epub 1900 01 01.

Application of Meta analysis in Occupational Health.

Liao X, Wang S.

Chinese Journal of Industrial Hygiene and Occupational Diseases. 2002; 20(3): 231-233.

The Implication of Environmental Temperature and Cold Air on the Mortality of Cardiovascular Disease in Beijing City

Liao X, Zongqun Zhao, Zongci Zhao.

Chinese General Medicine. 1999; : 56-57.