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Alessandra L. Moore, M.D.

Alessandra L. Moore, M.D.

Surgical Oncology , Surgery

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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About Me

Dr. Moore received her undergraduate degree from Hobart and William Smith Colleges, earning a Bachelors in Science (B.S.) and graduating with academic honors. After college, she trained for two years at the Massachusetts General Hospital BioMEMS Resource Center under Mehmet Toner, PhD and Sunitha Na...
Dr. Moore received her undergraduate degree from Hobart and William Smith Colleges, earning a Bachelors in Science (B.S.) and graduating with academic honors. After college, she trained for two years at the Massachusetts General Hospital BioMEMS Resource Center under Mehmet Toner, PhD and Sunitha Nagrath, PhD. There, she studied circulating tumor cells in whole blood and developed microfluidic devices. She next attended the University of Massachusetts Medical School where she was selected for the Clinical and Translational Research Pathway. After medical school, she completed internship and residency in General Surgery at Brigham and Women's Hospital, a Harvard teaching hospital. During her residency training, she completed a postdoctoral fellowship at Stanford University under Dr. Michael T. Longaker where she studied scarless wound healing. She also attended the Stanford Graduate School of Business "Ignite" Program, an executive education series focused on the translation of discoveries to business entities. After residency, she completed fellowship training in Endocrine Surgery at the Harvard Combined Endocrine Surgery Fellowship, where she trained with faculty from both Brigham and Women's Hospital as well as Massachusetts General Hospital.

Now recruited as faculty to the University of Rochester, Dr. Moore will provide cutting edge surgical care while also studying endocrine organ regeneration.

Area of Expertise
• Endocrine Surgery
• Tissue Engineering
• Thyroidectomy & Neck Dissection
• Open, Laparoscopic & Retroperitoneoscopic Adrenalectomy
• Minimally Invasive Parathyroidectomy

Area of Special Interest
• Thyroid Cancer & Disease
• Parathyroid Disease
• Adrenal Cancer & Disease
• Pheochromocytoma and Paraganglioma

"Endocrine Surgery was an easy choice for me. I value being a highly technical surgeon, an astute clinician, and investigating the cutting edge of surgical technology. Endocrine surgery is a unique field that combines fine technical skill in the operating room with sound clinical judgement. It’s also a field where technology advances can readily improve patient care and outcomes. With my background as a surgeon- scientist, I was drawn to the complex clinical and surgical dilemmas that occur in endocrine surgery patients every day. With my research, I aspire to make discoveries that will improve care for tomorrow’s patients.

I believe that patient care should be both evidence-based and individualized. It is important to understand the science behind each disease, behind each person’s biology, and then apply the two to arrive at the best treatment recommendations. Together with my patients, we will choose the best treatment options based on the current evidence, their biology, as well as their personal preference."

Faculty Appointments

Assistant Professor - Department of Surgery, Oncology (SMD)

Assistant Professor - Department of Medicine, Endocrine/Metabolism (SMD) - Joint


Residency & Fellowship

Fellowship, Endocrine Surgery, Brigham & Womens Hospital. 2021 - 2022

Fellowship, Stanford University Medical Center. 2016 - 2018

Residency, Surgery (General Surgery), Brigham & Womens Hospital. 2015 - 2021

Internship, Surgery (General Surgery), Brigham & Womens Hospital. 2014 - 2015


MD | University of Massachusetts Medical School. 2014


Journal Articles

More Than a Pause-Reply.

Moore AL, Smink DS, Rangel EL

JAMA surgery.. 2022 December 7 Epub 12/07/2022.

Higher SUV on FDG-PET is associated with shorter survival in adrenocortical carcinoma.

Wrenn SM, Moore AL, Shah HJ, Barletta JA, Vaidya A, Kilbridge KL, Doherty GM, Jacene HA, Nehs MA

American journal of surgery.. 2022 September 8 Epub 09/08/2022.

A Pregnant Pause-Time to Address Mentorship for Expectant Residents.

Moore AL, Smink DS, Rangel EL

JAMA surgery.. 2022 July 27 Epub 07/27/2022.

Trends in Diagnosis of Noninvasive Follicular Thyroid Neoplasm With Papillarylike Nuclear Features and Total Thyroidectomies for Patients With Papillary Thyroid Neoplasms.

Caulley L, Eskander A, Yang W, Auh E, Cairncross L, Cho NL, Golbon B, Iyer S, Liu JC, Lee PJ, Lindeman B, Meltzer C, Molin N, Moore A, Noel J, Nozolino H, Pasternak J, Price B, Ramsay T, Rolighed L, Sajisevi M, Sharma A, Sinclair C, Sorensen M, Tae K, Tang AL, Tsao G, Williams M, Wrenn S, Xing MH, Zafereo M, Stack BC, Randolph G, Davies L

JAMA otolaryngology-- head & neck surgery.. 2022 February 1148 (2):99-106. Epub 1900 01 01.

JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models.

Griffin MF, Borrelli MR, Garcia JT, Januszyk M, King M, Lerbs T, Cui L, Moore AL, Shen AH, Mascharak S, Diaz Deleon NM, Adem S, Taylor WL, desJardins-Park HE, Gastou M, Patel RA, Duoto BA, Sokol J, Wei Y, Foster D, Chen K, Wan DC, Gurtner GC, Lorenz HP, Chang HY, Wernig G, Longaker MT

Science translational medicine.. 2021 September 13 (609):eabb3312. Epub 09/01/2021.

Preventing activation in fibroblasts yields wound regeneration without scarring.

Mascharak S, desJardins-Park HE, Davitt MF, Griffin M, Borrelli MR, Moore AL, Chen K, Duoto B, Chinta M, Foster DS, Shen AH, Januszyk M, Kwon SH, Wernig G, Wan DC, Lorenz HP, Gurtner GC, Longaker MT

Science.. 2021 April 23372 (6540)Epub 1900 01 01.

Completion Thyroidectomy is Less Common Following Updated 2015 American Thyroid Association Guidelines.

Kuo LE, Angell TE, Pandian TK, Moore AL, Alexander EK, Barletta JA, Gawande AA, Lorch JH, Marqusee E, Moore FD, Nehs MA, Doherty GM, Cho NL

Annals of surgical oncology.. 2021 January 28 (1):484-491. Epub 06/24/2020.

Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis.

Leavitt T, Hu MS, Borrelli MR, Januszyk M, Garcia JT, Ransom RC, Mascharak S, desJardins-Park HE, Litzenburger UM, Walmsley GG, Marshall CD, Moore AL, Duoto B, Adem S, Foster DS, Salhotra A, Shen AH, Griffin M, Shen EZ, Barnes LA, Zielins ER, Maan ZN, Wei Y, Chan CKF, Wan DC, Lorenz HP, Chang HY, Gurtner GC, Longaker MT

Cell reports.. 2020 November 1033 (6):108356. Epub 1900 01 01.

Elucidating the fundamental fibrotic processes driving abdominal adhesion formation.

Foster DS, Marshall CD, Gulati GS, Chinta MS, Nguyen A, Salhotra A, Jones RE, Burcham A, Lerbs T, Cui L, King ME, Titan AL, Ransom RC, Manjunath A, Hu MS, Blackshear CP, Mascharak S, Moore AL, Norton JA, Kin CJ, Shelton AA, Januszyk M, Gurtner GC, Wernig G, Longaker MT

Nature communications.. 2020 August 1311 (1):4061. Epub 08/13/2020.

Doxycycline Reduces Scar Thickness and Improves Collagen Architecture.

Moore AL, desJardins-Park HE, Duoto BA, Mascharak S, Murphy MP, Irizarry DM, Foster DS, Jones RE, Barnes LA, Marshall CD, Ransom RC, Wernig G, Longaker MT

Annals of surgery.. 2020 July 272 (1):183-193. Epub 1900 01 01.

Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing.

Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prélot L, Ang CE, Shibuya Y, Benayoun BA, Chang ALS, Wernig M, Wysocka J, Longaker MT, Snyder MP, Brunet A

Nature.. 2019 October 574 (7779):553-558. Epub 10/23/2019.

In Vitro and In Vivo Osteogenic Differentiation of Human Adipose-Derived Stromal Cells.

Marshall CD, Brett EA, Moore AL, Wan DC, Longaker MT

Methods in molecular biology.. 2019 1891 :9-18. Epub 1900 01 01.

Author Correction: Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes.

Ransom RC, Foster DS, Salhotra A, Jones RE, Marshall CD, Leavitt T, Murphy MP, Moore AL, Blackshear CP, Brett EA, Wan DC, Longaker MT

Nature communications.. 2018 October 199 (1):4411. Epub 10/19/2018.

Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes.

Ransom RC, Foster DS, Salhotra A, Jones RE, Marshall CD, Leavitt T, Murphy MP, Moore AL, Blackshear CP, Brett EA, Wan DC, Longaker MT

Nature communications.. 2018 July 309 (1):2971. Epub 07/30/2018.

A Fibroblast Is Not a Fibroblast Is Not a Fibroblast.

Hu MS, Moore AL, Longaker MT

The Journal of investigative dermatology.. 2018 April 138 (4):729-730. Epub 1900 01 01.

Scarless wound healing: Transitioning from fetal research to regenerative healing.

Moore AL, Marshall CD, Barnes LA, Murphy MP, Ransom RC, Longaker MT

Wiley interdisciplinary reviews. Developmental biology.. 2018 March 7 (2)Epub 01/09/2018.

Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation.

Barnes LA, Marshall CD, Leavitt T, Hu MS, Moore AL, Gonzalez JG, Longaker MT, Gurtner GC

Advances in wound care.. 2018 February 17 (2):47-56. Epub 1900 01 01.

Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair.

Hu MS, Walmsley GG, Barnes LA, Weiskopf K, Rennert RC, Duscher D, Januszyk M, Maan ZN, Hong WX, Cheung AT, Leavitt T, Marshall CD, Ransom RC, Malhotra S, Moore AL, Rajadas J, Lorenz HP, Weissman IL, Gurtner GC, Longaker MT

JCI insight.. 2017 October 52 (19)Epub 10/05/2017.

Surgical Treatment of Extraesophageal Manifestations of Gastroesophageal Reflux Disease.

Sidwa F, Moore AL, Alligood E, Fisichella PM

World journal of surgery.. 2017 October 41 (10):2566-2571. Epub 1900 01 01.

The Role of Skeletal Stem Cells in the Reconstruction of Bone Defects.

Murphy MP, Irizarry D, Lopez M, Moore AL, Ransom RC, Longaker MT, Wan DC, Chan CKF

The Journal of craniofacial surgery.. 2017 July 28 (5):1136-1141. Epub 1900 01 01.

Minimizing Skin Scarring through Biomaterial Design.

Moore AL, Marshall CD, Longaker MT

Journal of functional biomaterials.. 2017 January 218 (1)Epub 01/21/2017.

Diagnosis and Treatment of the Extraesophageal Manifestations of Gastroesophageal Reflux Disease.

Sidhwa F, Moore A, Alligood E, Fisichella PM

Annals of surgery.. 2017 January 265 (1):63-67. Epub 1900 01 01.

"Universal" vitrification of cells by ultra-fast cooling.

Heo YS, Nagrath S, Moore AL, Zeinali M, Irimia D, Stott SL, Toth TL, Toner M

Technology.. 2015 March 3 (1):64-71. Epub 1900 01 01.

Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer.

Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, Dahl DM, Wu CL, Iafrate AJ, Smith MR, Tompkins RG, Sequist LV, Toner M, Haber DA, Maheswaran S

Science translational medicine.. 2010 March 312 (25):25ra23. Epub 1900 01 01.


GMKA: Global Medical Knowledge Alliance (2022)

Chapter: Adrenocortical Carcinoma

Authors: Alessandra L. Moore, Matthew A. Nehs

Publisher: GMKA: Global Medical Knowledge Alliance 2022

Principles of Regenerative Medicine (2019)

Chapter: Scarless Wound Healing: From Experimental Target to Clinical Reality

Authors: Alessandra L. Moore, Clement D. Marshall, Allison Nauta, Hermann P. Lorenz, Michael T. Longaker

Publisher: Elsevier, Inc. 2019

Ratings & Reviews

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