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Saturday, July 20: All UR Medicine facilities are open as scheduled and providing safe patient care, with a goal to return all clinical services to full efficiency by early next week.

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Jamie K. Capal, M.D.

Jamie K. Capal, M.D.

she/her/hers

Pediatrics , Child Neurology

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
Accepting New Patients

Contact

Call Center (585) 276-3000

About Me

Certified Specialties

Child Neurology - American Board of Psychiatry & Neurology

Neurodevelopmental Disabilities - American Board of Psychiatry & Neurology

Faculty Appointments

Interim Professor - Department of Neurology, Child Neurology (SMD)

Interim Professor - Department of Neurology, Center for Health and Technology (SMD) - Joint

Interim Professor - Department of Neuroscience (SMD) - Joint

Interim Professor - Department of Pediatrics (SMD) - Joint

Credentials

Residency & Fellowship

Residency, Pediatric Neurology, Cincinnati Children's Hospital Medical Center. 2008 - 2012

Residency, Pediatrics, Cincinnati Children's Hospital Medical Center. 2006 - 2008

Education

MD | Albany Medical College. 2006

Publications

Journal Articles

Abnormality of Early White Matter Development in Tuberous Sclerosis Complex and Autism Spectrum Disorder: Longitudinal Analysis of Diffusion Tensor Imaging Measures.

Srivastava S, Yang F, Prohl AK, Davis PE, Capal JK, Filip-Dhima R, Bebin EM, Krueger DA, Northrup H, Wu JY, Warfield SK, Sahin M, Zhang B,

Journal of child neurology.. 2024 May 39 (5-6):178-189. Epub 05/15/2024.

Autism and Epilepsy.

Capal JK, Jeste SS

Pediatric clinics of North America.. 2024 April 71 (2):241-252. Epub 02/02/2024.

Correction: Understanding the impact of tuberous sclerosis complex: development and validation of the TSC-PROM.

Müller AR, Luijten MAJ, Haverman L, de Ranitz-Greven WL, Janssens P, Rietman AB, Hoopen LWT, de Graaff LCG, de Wit MC, Jansen AC, Gipson T, Capal JK, de Vries PJ, van Eeghen AM

BMC medicine.. 2023 October 2321 (1):401. Epub 10/23/2023.

Development and Feasibility of the Self-Report Quantified Tuberous Sclerosis Complex-Associated Neuropsychiatric Disorders Checklist (TAND-SQ).

Heunis TM, Chambers N, Vanclooster S, Bissell S, Byars AW, Capal JK, Cukier S, Davis PE, de Vries MC, De Waele L, Flinn J, Gardner-Lubbe S, Gipson T, Kingswood JC, Krueger DA, Kumm AJ, Sahin M, Schoeters E, Smith C, Srivastava S, Takei M, van Eeghen AM, Waltereit R, Jansen AC, de Vries PJ

Pediatric neurology.. 2023 October 147 :101-123. Epub 07/07/2023.

International consensus recommendations for the identification and treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND).

de Vries PJ, Heunis TM, Vanclooster S, Chambers N, Bissell S, Byars AW, Flinn J, Gipson TT, van Eeghen AM, Waltereit R, Capal JK, Cukier S, Davis PE, Smith C, Kingswood JC, Schoeters E, Srivastava S, Takei M, Gardner-Lubbe S, Kumm AJ, Krueger DA, Sahin M, De Waele L, Jansen AC

Journal of neurodevelopmental disorders.. 2023 September 1415 (1):32. Epub 09/14/2023.

Understanding the impact of tuberous sclerosis complex: development and validation of the TSC-PROM.

Müller AR, Luijten MAJ, Haverman L, de Ranitz-Greven WL, Janssens P, Rietman AB, Ten Hoopen LW, de Graaff LCG, de Wit MC, Jansen AC, Gipson T, Capal JK, de Vries PJ, van Eeghen AM

BMC medicine.. 2023 August 821 (1):298. Epub 08/08/2023.

Describing autism spectrum disorder in tuberous sclerosis complex: Challenges and future opportunities.

Capal JK

Developmental medicine and child neurology.. 2022 October 64 (10):1183. Epub 05/28/2022.

The research landscape of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND)-a comprehensive scoping review.

Vanclooster S, Bissell S, van Eeghen AM, Chambers N, De Waele L, Byars AW, Capal JK, Cukier S, Davis P, Flinn J, Gardner-Lubbe S, Gipson T, Heunis TM, Hook D, Kingswood JC, Krueger DA, Kumm AJ, Sahin M, Schoeters E, Smith C, Srivastava S, Takei M, Waltereit R, Jansen AC, de Vries PJ

Journal of neurodevelopmental disorders.. 2022 February 1314 (1):13. Epub 02/13/2022.

Empowering Families Through Technology: A Mobile-Health Project to Reduce the TAND Identification and Treatment Gap (TANDem).

Heunis TM, Bissell S, Byars AW, Capal JK, Chambers N, Cukier S, Davis PE, De Waele L, Flinn J, Gardner-Lubbe S, Gipson T, Kingswood JC, Krueger DA, Kumm AJ, Sahin M, Schoeters E, Smith C, Srivastava S, Takei M, Vanclooster S, van Eeghen AM, Waltereit R, Jansen AC, de Vries PJ

Frontiers in psychiatry.. 2022 13 :834628. Epub 02/28/2022.

Symptom rates and profile clustering in tuberous sclerosis complex-associated neuropsychiatric disorders (TAND).

Alperin S, Krueger DA, Franz DN, Agricola KD, Stires G, Horn PS, Capal JK

Journal of neurodevelopmental disorders.. 2021 December 1313 (1):60. Epub 12/13/2021.

Profile of Autism Spectrum Disorder in Tuberous Sclerosis Complex: Results from a Longitudinal, Prospective, Multisite Study.

Capal JK, Williams ME, Pearson DA, Kissinger R, Horn PS, Murray D, Currans K, Kent B, Bebin M, Northrup H, Wu JY, Sahin M, Krueger DA,

Annals of neurology.. 2021 December 90 (6):874-886. Epub 10/29/2021.

Epilepsy Is Heterogeneous in Early-Life Tuberous Sclerosis Complex.

Ihnen SKZ, Capal JK, Horn PS, Griffith M, Sahin M, Bebin EM, Wu JY, Northrup H, Krueger DA,

Pediatric neurology.. 2021 October 123 :1-9. Epub 07/06/2021.

Clinical trial strategies for rare neurodevelopmental disorders: challenges and opportunities.

Krishnan ML, Berry-Kravis E, Capal JK, Carpenter R, Gringras P, Hipp JF, Miller MT, Mingorance A, Philpot BD, Pletcher MT, Rotenberg A, Tjeertes J, Wang PP, Willgoss T, de Wit MC, Jeste SS

Nature reviews. Drug discovery.. 2021 September 20 (9):653-654. Epub 1900 01 01.

Leukodystrophies in Children: Diagnosis, Care, and Treatment.

Bonkowsky JL, Keller S,

Pediatrics.. 2021 September 148 (3)Epub 1900 01 01.

Diabetes in Individuals With Tuberous Sclerosis Complex Treated With mTOR Inhibitors.

Agricola K, Stires G, Krueger DA, Capal JK, Franz DN, Ritter DM

Pediatric neurology.. 2021 July 120 :7-10. Epub 04/02/2021.

Frequency, Progression, and Current Management: Report of 16 New Cases of Nonfunctional Pancreatic Neuroendocrine Tumors in Tuberous Sclerosis Complex and Comparison With Previous Reports.

Mowrey K, Northrup H, Rougeau P, Hashmi SS, Krueger DA, Ebrahimi-Fakhari D, Towbin AJ, Trout AT, Capal JK, Franz DN, Rodriguez-Buritica D

Frontiers in neurology. 2021 12 :627672. Epub 04/09/2021.

Epilepsy and TSC-Associated Neuropsychiatric Disorders.

Capal JK

Pediatric neurology briefs.. 2020 December 234 :11. Epub 12/02/2020.

Routine Neuroimaging of the Preterm Brain.

Hand IL, Shellhaas RA, Milla SS,

Pediatrics.. 2020 November 146 (5)Epub 1900 01 01.

Factors Associated With Seizure Onset in Children With Autism Spectrum Disorder.

Capal JK, Macklin EA, Lu F, Barnes G

Pediatrics.. 2020 April 145 (Suppl 1):S117-S125. Epub 1900 01 01.

Language predictors of autism spectrum disorder in young children with tuberous sclerosis complex.

Schoenberger A, Capal JK, Ondracek A, Horn PS, Murray D, Byars AW, Pearson DA, Williams ME, Bebin M, Northrup H, Wu JY, Sahin M, Krueger DA

Epilepsy & behavior : E&B.. 2020 February 103 (Pt A):106844. Epub 12/18/2019.

Impacting development in infants with tuberous sclerosis complex: Multidisciplinary research collaboration.

Williams ME, Pearson DA, Capal JK, Byars AW, Murray DS, Kissinger R, O'Kelley SE, Hanson E, Bing NM, Kent B, Wu JY, Northrup H, Bebin EM, Sahin M, Krueger D,

The American psychologist.. 2019 April 74 (3):356-367. Epub 1900 01 01.

Short-term safety of mTOR inhibitors in infants and very young children with tuberous sclerosis complex (TSC): Multicentre clinical experience.

Krueger DA, Capal JK, Curatolo P, Devinsky O, Ess K, Tzadok M, Koenig MK, Narayanan V, Ramos F, Jozwiak S, de Vries P, Jansen AC, Wong M, Mowat D, Lawson J, Bruns S, Franz DN,

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.. 2018 November 22 (6):1066-1073. Epub 07/04/2018.

EEG endophenotypes in autism spectrum disorder.

Capal JK, Carosella C, Corbin E, Horn PS, Caine R, Manning-Courtney P

Epilepsy & behavior : E&B.. 2018 November 88 :341-348. Epub 10/17/2018.

Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells.

Li C, Liu X, Liu Y, Zhang E, Medepalli K, Masuda K, Li N, Wikenheiser-Brokamp KA, Osterburg A, Borchers MT, Kopras EJ, Plas DR, Sun J, Franz DN, Capal JK, Mays M, Sun Y, Kwiatkowski DJ, Alayev A, Holz MK, Krueger DA, Siroky BJ, Yu JJ

Molecular cancer research : MCR.. 2017 October 15 (10):1318-1330. Epub 07/14/2017.

Utility of the Autism Observation Scale for Infants in Early Identification of Autism in Tuberous Sclerosis Complex.

Capal JK, Horn PS, Murray DS, Byars AW, Bing NM, Kent B, Bucher LA, Williams ME, O'Kelley S, Pearson DA, Sahin M, Krueger DA,

Pediatric neurology.. 2017 October 75 :80-86. Epub 06/27/2017.

Influence of seizures on early development in tuberous sclerosis complex.

Capal JK, Bernardino-Cuesta B, Horn PS, Murray D, Byars AW, Bing NM, Kent B, Pearson DA, Sahin M, Krueger DA,

Epilepsy & behavior : E&B.. 2017 May 70 (Pt A):245-252. Epub 04/28/2017.

Profile of everolimus in the treatment of tuberous sclerosis complex: an evidence-based review of its place in therapy.

Capal JK, Franz DN

Neuropsychiatric disease and treatment.. 2016 12 :2165-72. Epub 08/25/2016.

Books

Epilepsy: A Comprehensive Textbook, 3rd Edition (2023)

Chapter: Autism and Epilepsy

Authors: Jamie K. Capal, Karen Ballaban-Gil, Sarah Spence

Publisher: Wolters Kluwer Health 2023

Differential Diagnosis of Autism Spectrum Disorder (2022)

Chapter: Autism Spectrum Disorders versus Genetic Syndromes

Authors: Jamie Capal, Shafali Jeste

Publisher: Oxford University Press 2022

Neurobiology of Disease, Second Edition (2016)

Chapter: Familial CNS Tumor Syndromes: Tuberous Sclerosis

Authors: Darcy Krueger, Jamie Capal

Publisher: Oxford University Press 2016