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URMC Response to CrowdStrike Software Issue

Saturday, July 20: All UR Medicine facilities are open as scheduled and providing safe patient care, with a goal to return all clinical services to full efficiency by early next week.

Patients: click here for more information. Faculty/Staff: click here for information.

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Andrew T. Nelson, M.D., Ph.D.

UR Medicine Labs

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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About Me

Faculty Appointments

Assistant Professor - Department of Pathology and Laboratory Medicine (SMD)

Credentials

Residency & Fellowship

Residency, Pathology, Anatomic Pathology & Clinical Pathology, University of Texas Southwestern Medical Center. 2021 - 2024

Education

MD | The University of Texas Medical Branch at Galveston. 2021

Awards

Chateaubriand Fellowship Laureate. 2018 - 2019

Dean's Prestigious Fellowship Supplement. 2017 - 2018

James R Domengeaux Scholarship. 2009 - 2010

The Honor Society of Phi Kappa Phi. 2008

Blue Key National Honor Society. 2007

Publications

Journal Articles

Successful use of lenalidomide to treat refractory acquired von Willebrand disease associated with monoclonal gammopathy.

Green A, Shen YP, Nelson AT, Sarode R, Ibrahim IF, Cao J, Afraz S, Yates SG

Annals of hematology.. 2022 December 101 (12):2627-2631. Epub 10/04/2022.

ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids.

Patel R, Santoro A, Hofer P, Tan D, Oberer M, Nelson AT, Konduri S, Siegel D, Zechner R, Saghatelian A, Kahn BB

Nature.. 2022 June 606 (7916):968-975. Epub 06/08/2022.

Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line.

Weisz HA, Boone DR, Coggins WS, Edwards GA, Willey HE, Widen SG, Siegel D, Nelson AT, Prough DS, Hellmich HL

PloS one.. 2022 17 (6):e0267682. Epub 06/03/2022.

Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs).

Aryal P, Syed I, Lee J, Patel R, Nelson AT, Siegel D, Saghatelian A, Kahn BB

Journal of lipid research.. 2021 62 :100108. Epub 08/18/2021.

Total Synthesis of Micrococcin P1 through Scalable Thiazole Forming Reactions of Cysteine Derivatives and Nitriles.

Christy MP, Johnson T, McNerlin CD, Woodard J, Nelson AT, Lim B, Hamilton TL, Freiberg KM, Siegel D

Organic letters.. 2020 March 2022 (6):2365-2370. Epub 03/05/2020.

Global chemical effects of the microbiome include new bile-acid conjugations.

Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC

Nature.. 2020 March 579 (7797):123-129. Epub 02/26/2020.

PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms.

Zhou P, Santoro A, Peroni OD, Nelson AT, Saghatelian A, Siegel D, Kahn BB

The Journal of clinical investigation.. 2019 October 1129 (10):4138-4150. Epub 1900 01 01.

PAHSAs attenuate immune responses and promote ? cell survival in autoimmune diabetic mice.

Syed I, Rubin de Celis MF, Mohan JF, Moraes-Vieira PM, Vijayakumar A, Nelson AT, Siegel D, Saghatelian A, Mathis D, Kahn BB

The Journal of clinical investigation.. 2019 August 5129 (9):3717-3731. Epub 08/05/2019.

Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases

Burke, J. R.; La Clair, J. J.; Philippe, R. N.; Pabis, A.; Corbella, M.; Jez, J. M.; Cortina, G. A.; Kaltenbach, M.; Bowman, M. E.; Louie, G. V.; Woods, K. B.; Nelson, A. T.; Tawfik, D. S.; Kamerlin, S. C. L.; Noel, J. P.

ACS Catalysis. 2019; 9(9): 8388–8396.

Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements.

Kolar MJ, Nelson AT, Chang T, Ertunc ME, Christy MP, Ohlsson L, Härröd M, Kahn BB, Siegel D, Saghatelian A

Analytical chemistry.. 2018 April 1790 (8):5358-5365. Epub 03/26/2018.

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

Syed I, Lee J, Moraes-Vieira PM, Donaldson CJ, Sontheimer A, Aryal P, Wellenstein K, Kolar MJ, Nelson AT, Siegel D, Mokrosinski J, Farooqi IS, Zhao JJ, Yore MM, Peroni OD, Saghatelian A, Kahn BB

Cell metabolism.. 2018 February 627 (2):419-427.e4. Epub 1900 01 01.

Efficacy of Ebselen and BAY 11-7082 Against .

Debnath A, Nelson AT, Silva-Olivares A, Shibayama M, Siegel D, McKerrow JH

Frontiers in microbiology.. 2018 9 :414. Epub 03/06/2018.

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation.

Nelson AT, Kolar MJ, Chu Q, Syed I, Kahn BB, Saghatelian A, Siegel D

Journal of the American Chemical Society.. 2017 April 5139 (13):4943-4947. Epub 03/28/2017.

Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties.

Nelson AT, Camelio AM, Claussen KR, Cho J, Tremmel L, DiGiovanni J, Siegel D

Bioorganic & medicinal chemistry letters.. 2015 October 125 (19):4342-6. Epub 07/22/2015.

The diversity and molecular modelling analysis of B?? and B??-independent glycerol dehydratases.

Liu Y, Gallo AA, Bajpai RK, Chistoserdov A, Nelson A, Segura L, Xu W

International journal of bioinformatics research and applications.. 2010 6 (5):484-507. Epub 1900 01 01.