CONTACT INFORMATIONCREDENTIALSPUBLICATIONSDouglas Stuart Portman, Ph.D.Contact InformationPhone NumbersAdministrative: (585) 273-1749Office: (585) 275-7414Fax: (585) 276-1947LocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 645Rochester, NY 14642Additional LinksPortman Lab WebsiteFaculty AppointmentsProfessor - Department of Biomedical Genetics (SMD) Professor - Department of Biology RC (RC) - JointProfessor - Department of Neuroscience (SMD) - JointBiographyResearchGenetic Control of Sex Differences in Neurobiology and Disease Though the existence of two sexes is a fundamental characteristic of nearly all animal species, the way biological sex brings about sex differences in the brain and behavior is poorly understood. Moreover, susceptibility to a host of human neurological and mental health disorders is strongly influenced by gender, but in most cases the biological bases for these differences remain opaque. Our research uses a simple, experimentally tractable model system--the small soil nematode C. elegans--to shed light on the genetic underpinnings of sex differences in neural development, behavior, and disease susceptibility. For more information, please visit the lab website at: http://wormweb.urmc.rochester.edu/CredentialsEducation1988BA with Honors, | Univ of PennsylvaniaBiochemistry1995PhD | Univ of PennsylvaniaMolecular Biology and GeneticsPublicationsJournal Articles1/19/2023Burkhardt RN, Artyukhin AB, Aprison EZ, Curtis BJ, Fox BW, Ludewig AH, Palomino DF, Luo J, Chaturbedi A, Panda O, Wrobel CJJ, Baumann V, Portman DS, Lee SS, Ruvinsky I, Schroeder FC. "Sex-specificity of the C. elegans metabolome." Nature communications.. 2023 Jan 19; 14(1):320. Epub 2023 Jan 19. 9/1/2022Pechuk V, Goldman G, Salzberg Y, Chaubey AH, Bola RA, Hoffman JR, Endreson ML, Miller RM, Reger NJ, Portman DS, Ferkey DM, Schneidman E, Oren-Suissa M. "Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior." Current biology : CB.. 2022 Sep 1; Epub 2022 Sep 01. 8/19/2021Luo J, Portman DS. "Sex-specific, pdfr-1-dependent modulation of pheromone avoidance by food abundance enables flexibility in C. elegans foraging behavior." Current biology : CB.. 2021 Aug 19; Epub 2021 Aug 19. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Douglas Stuart Portman, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Douglas Stuart Portman, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.