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Jill Marie Cholette, M.D.

Contact Information

Phone Numbers

Office: (585) 275-8138

Fax: (585) 276-2627

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentNot Accepting New Patients

Faculty Appointments

Patient Care Settings

Hospital Medicine, Pediatrics



Professional Background

Jill Cholette received her Undergraduate Degree from Mount Holyoke College and completed Medical School and Internal Medicine/Pediatric Residency at the University of Rochester. She is a double-boarded Pediatric Cardiac Intensivist who completed her Pediatric Cardiology and Pediatric Critical Care Fellowships at the University of Rochester. Her primary clinical research interests are in patient blood management, blood conservation and modification, and coagulation and hemostasis. She is on the executive committee of the PALISI BloodNet subgroup and on the Society for the Advancement of Blood Management (SABM) research committee. She is the Medical Director for the Pediatric Cardiac Care Center and Pediatric Intensive Care Unit at the University of Rochester, and is the Chief of the Division of Pediatric Critical Care.


Dr. Jill Cholette has research interests in thrombosis and use of blood products in critically ill pediatric patients, particularly those undergoing cardiac surgery. Dr. Cholette is working to clarify the role of inflammation in the development of thrombosis, and to determine the optimal anticoagulation regimen for the pediatric post-op cardiac surgery patient.

Her other work involves blood utilization in the pediatric ICU patient, and she is developing a transfusion strategy for the pediatric post-op cardiac surgery patients.

Dr. Cholette's clinical interests are: thrombosis, hemostasis, and inflammation.

Scientific Reviewer for Pediatric Clinical Research Organization (PCRO) at URMC 2009-present

Scientific Reviewer for Strong Children's Research Center Small Grant Program URMC June 2013

Journal Reviewer:
The Annals of Thoracic Surgery 2007-present
Thrombosis Research 2008-present
Postgraduate Medicine 2009-present

Pediatric Acute Lung Injury and Sepsis (PALISI) Member
March 2010-present

Pediatric Blood Research Network (BLOOD NET) Member
September 2011-present

Prevalence of Acute critical Neurologic disease in children: a Global Epidemiological Assessment (PANGEA). November 2011-present; PI: Erika Fink; University of Pittsburgh
Site PI: Jill M. Cholette

Prophylaxis against thrombosis practice (PROTRACT) Study February 2012-present
PI: Vince Faustino MD; Yale University Site PI: Jill M. Cholette

Ongoing studies:
Prospective randomized controlled clinical trial comparing a restrictive v. liberal transfusion strategy in neonates and infants undergoing surgery for congenital heart disease. Principle Investigator: Cholette JM

Impact of washed blood on outcomes in adults with acute leukemia.
Co-principle investigator: Cholette JM

Comparing Ultrasound Dilution with Fick Principle in Assessing Cardiac Output and Shunt Fraction in Patients with Congenital Heart Disease.
Co-investigator Cholette JM.

Identification and significance of biologic mediators in red cell concentrates.
Co-investigator: Cholette JM

An investigation of the adverse effects of the storage age of RBC transfusions to critically ill medical patients.
Co-investigator: Cholette JM



MD | University of Rochester School of Medicine/Dentistry

Post-doctoral Training & Residency

01/01/2011 - 01/31/2014
Fellowship in Pediatric Cardiology at University of Rochester Medical Center

08/10/2003 - 07/31/2006
Fellowship in Pediatric Critical Care Medicine at University of Rochester Medical Center

07/01/2000 - 08/09/2003
Residency in Pediatrics, Internal Medicine at University of Rochester Medical Center

07/01/1999 - 06/30/2000
Internship in Pediatrics, Internal Medicine at University of Rochester Medical Center

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Therapeutics Specialty Award
Sponsor: Society of Critical Care Medicine
Location: Houston, TX

Research Citation Finalist
Sponsor: Society of Critical Care Medicine
Location: Houston, TX

2007 - 2010
Strong Children's Research Center New Investigator
Sponsor: URMC
Location: Rochester, NY

Clausen-Bradford Fellowship Training Award

2000 - 2000
David A. Haller Award - outstanding devotion and contribution to patient care

Alpha Omega Alpha Honors Medical Society
Location: South Hadley, MA

The Bryce Collier Prize (student whose performance demonstrates exceptional qualities of responsibility

The Benjamin Rush Prize (4th yr med student who gave unusual promise of creative scholars

The Glasgow Citation (awarded by the American Medical Women's Assoc to those whose academic work is high quality

American Medical Women's Association Award

Sigma Xi, The Scientific Research Society

Psi Chi, The National Honor Society in Psychology

1993 - 1994
Who's Who Among Students in American Universities & Colleges

Sarah Williston Scholar for academic excellence

Abbey Howe Turner Award excellence in biological sciences

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Journal Articles

Abadeer M, Swartz MF, Martin SD, Groves AM, Kent AL, Schwartz GJ, Brophy P, Alfieris GM, Cholette JM. "Using Serum Cystatin C to Predict Acute Kidney Injury Following Infant Cardiac Surgery." Pediatric cardiology.. 2023 Jan 13; Epub 2023 Jan 13.

Benamar M, Chen Q, Chou J, Julé AM, Boudra R, Contini P, Crestani E, Lai PS, Wang M, Fong J, Rockwitz S, Lee P, Chan TMF, Altun EZ, Kepenekli E, Karakoc-Aydiner E, Ozen A, Boran P, Aygun F, Onal P, Sakalli AAK, Cokugras H, Gelmez MY, Oktelik FB, Cetin EA, Zhong Y, Taylor ML, Irby K, Halasa NB, Mack EH, , Signa S, Prigione I, Gattorno M, Cotugno N, Amodio D, Geha RS, Son MB, Newburger J, Agrawal PB, Volpi S, Palma P, Kiykim A, Randolph AG, Deniz G, Baris S, De Palma R, Schmitz-Abe K, Charbonnier LM, Henderson LA, Chatila TA. "The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children." The Journal of clinical investigation.. 2023 Jan 3; 133(1)Epub 2023 Jan 03.

Swartz MF, Yoshitake S, Cholette JM, Atallah-Yunes N, Wang H, Alfieris GM. "A modified approach in the repair of type I and II truncus arteriosus to promote branch pulmonary arterial growth and limit early reoperation." JTCVS techniques.. 2022 Dec; 16:196-211. Epub 2022 Sep 29.

Books & Chapters

Chapter Title: Use of blood products
Book Title: Pediatric Critical Care Study Guide
Author List: Cholette, JM; Lerner, NB
Published By: Springer-Verlag 2012 in London

Chapter Title: Esophageal Caustic Injury
Book Title: Textbook of Pediatric Care
Author List: J Cholette; G Drugas.
Edited By: McInerny TK; Adam HM; Campbell DE; Kamat DK; Kelleher KJ
Published By: American Academy of Pediatrics 2008 in Elk Grove Village, IL

Chapter Title: Toxic Exposures: Diagnosis and Management
Book Title: Pediatric Critical Care Medicine: Basic Science & Clinical Evidence
Author List: J Cholette; KS Powers; P. Abboud
Edited By: Wheeler DS; Wong, HR; Shanley, TP.
Published By: Springer-Verlag 2007