CONTACT INFORMATIONCREDENTIALSAWARDSPUBLICATIONSXinping Zhang, B.Med., Ph.D.Contact InformationPhone NumbersOffice: (585) 275-7928Research LabsThe Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.Visit The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006. Lab WebsiteLocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box 665Rochester, NY 14642Faculty AppointmentsAssociate Professor - Department of Orthopaedics , Center for Musculoskeletal Research (SMD) BiographyResearchDr. Zhang's research centers on finding ways to "revitalize, " or reactivate the healing processes of bone. When people suffer massive bone loss due to traumatic injury or a tumor, bone grafts are used to restore the shape and strength of the bone. Even when a bone graft from the patient's own body is used, healing and strengthening are sometimes never complete. By studying how our body's cells mature to become bone-forming cells, Dr. Zhang hopes to find ways to turn the process of healing on so that the entire bone graft will heal after surgery. Adult mesenchymal stem cells (MSCs) have enormous potential for bone tissue repair and regeneration. Our research has been focused on understanding the molecular and cellular mechanisms that control the activation, proliferation and differentiation of mesenchymal stem cells during skeletal repair. We are particularly interested in the periosteal stem cells that play key roles in repair and regeneration. Our current program has integrated the following topics: 1) Molecular signals that control mesenchymal stem cell differentiation. 2) Mechanism of skeletal repair and regeneration 3) Stem cell therapy and bone tissue engineering for repair and reconstruction of large segmental defects.CredentialsEducation1990MD | China-Shanghai Medical UniversityMedicine1993MS, | China-Shanghai Medical UniversityBiochemistry1999PhD, | University of Rochester School of Medicine & DentistryBiochemistryAwards2008MTF J.R. Neff Award2005Orthopaedic Research Society New Investigator Recognition AwardLocation: Chicago, IL2002Orthopaedic Research Society Travel Fellowship AwardLocation: Chicago, ILVIEW ALL expand_morePublicationsJournal Articles7/26/2021Zhai Y, Schilling K, Wang T, El Khatib M, Vinogradov S, Brown EB, Zhang X. "Spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of biomimetic nanofiber-enabled bone tissue engineering." Biomaterials.. 2021 Jul 26; 276:121041. Epub 2021 Jul 26. 6/12/2021Lam LRW, Schilling K, Romas S, Misra R, Zhou Z, Caton JG, Zhang X. "Electrospun core-shell nanofibers with encapsulated enamel matrix derivative for guided periodontal tissue regeneration." Dental materials journal.. 2021 Jun 12; Epub 2021 Jun 12. 11/9/2020Zhuang Z, John JV, Liao H, Luo J, Rubery P, Mesfin A, Boda SK, Xie J, Zhang X. "Periosteum Mimetic Coating on Structural Bone Allografts Electrospray Deposition Enhances Repair and Reconstruction of Segmental Defects." . 2020 Nov 9; 6(11):6241-6252. Epub 2020 Oct 22. VIEW ALL PUBLICATIONSClose WindowSchedule an appointment with Xinping Zhang, B.Med., Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Xinping Zhang, B.Med., Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.