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Chin-To Fong, M.D.

Contact Information

Phone Numbers

Appointment: (585) 275-5857

Office: (585) 275-5857

Fax: (585) 273-1018

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Faculty Appointments

Patient Care Settings

Cancer, Genetics, Medicine, Pediatrics


Dr, Fong provide care for newborns, children, teens, and adults who have genetic and metabolic disorders. He treats a variety of conditions, including birth defects, chromosome abnormalities, cystic fibrosis, developmental disabilities, Fragile X syndrome, Neurofibromatosis, Marfan syndrome, Prader-Willi and Angelman syndrome, Skeletal dysplasias and inborn errors of metabolism, including Medium-Chain Acyl-CoA Dehydrogenase deficiency (MCADD) and Phenylketonuria (PKU).

Dr. Fong has extensive experience working in his field and the Chief of Pediatric Genetics.


Dr. Fong's primary research interest is Genetics of orofacial clefts. Cleft lip and palate is a common birth defect that affects one in 700 children in the U. S. and around the world. Children with this birth defect face multiple challenges, such as feeding difficulty, hearing impairment, speech defects and many dental abnormalities. These problems, along with the cosmetic changes associated with the clefts, often result in life-long physical, educational and psychological handicaps. Caring of these children thus requires a team approach over long periods of time.

Cleft lip and palate is a familial trait, but the genetic factors that result in this abnormality have not been clearly identified. Recent calculations have led to the belief that as many as a couple dozen genetic factors may act together to cause cleft lip and palate, with a few of the factors being more important than the rest. Moreover, there is convincing evidence that environment factors, such as cigarette smoking by the pregnant mother, play a role in the development of cleft lip and palate in the fetus.

In these situations, the environmental and genetic factors act together to cause the birth defect. Therefore, cleft lip and palate is considered a multifactorial genetic disorder. The work in our laboratory is focused on finding the genetic factors for cleft lip and palate through linkage disequilibrium analyses. We believe that better treatment and prevention of cleft lip and palate will come from a better understanding of these genetic and environmental factors.



MD | Harvard Medical School

Post-doctoral Training & Residency

07/01/1984 - 06/30/1987
Fellowship at St. Louis University Nephrology Fellowship Program

07/01/1982 - 06/30/1984
Residency in Pediatrics at Washington University School Of Medicine

07/01/1981 - 06/30/1982
Internship in Pediatrics at Washington University School Of Medicine

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Arnold P. Gold Humanism Honor Society Inductee
Sponsor: Arnold P. Gold Foundation

The Association of American Medical Colleges Arnold P. Gold Foundation Humanism in Medicine Award
Sponsor: Arnold P. Gold Foundation

Elected Student Marshall for Commencement Exercise
Sponsor: URSMD

Elected Alpha Omega Alpha Zeta Chapter Annual Lecturer
Sponsor: Class of 2008 AOA inductees, URSMD

2007 - 2013
Leonard Tow Humanism in Medicine Award
Sponsor: Arnold P. Gold Foundation

Gold Medal Award for Excellence in Teaching
Sponsor: Alumni Association, URSMD

2004 - 2005
Manuel D. Goldman Prize for Excellence in First Year Teaching
Sponsor: University of Rochester School of Med. and Dent.
Location: Rochester, NY

Elected member of Alpha Omega Alpha Zeta Chapter
Sponsor: Class of 2005, URSMD

First Annual Loss Science Lecturer
Sponsor: St. John Fisher College
Location: Rochester, NY

Elected Faculty Commencement Speaker
Sponsor: the URSMD Class of 2004

Outstanding Faculty Teaching Award
Sponsor: Medical Students Class of 2005

Commendation for First Year Teaching
Sponsor: URSMD

URSMD Nominee of the American Association of Medical Colleges Award for Humanism in Medicine
Sponsor: Received commendation from the American Assoc. Medical Colleges

2002 - 2003
DeWitt Brower Dean's Teaching Fellowship
Sponsor: URSMD

Manuel D. Goldman Prize for Excellence in First Year Teaching
Sponsor: URSMD

Ruth A. Lawrence Academic Faculty Service Award, Department of Pediatrics,
Sponsor: URSMD

1993 - 1994
Outstanding Faculty Teaching Award given by the Pediatrics Housestaff
Sponsor: Strong Memorial Hospital

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Journal Articles

Yuan B, Neira J, Pehlivan D, Santiago-Sim T, Song X, Rosenfeld J, Posey JE, Patel V, Jin W, Adam MP, Baple EL, Dean J, Fong CT, Hickey SE, Hudgins L, Leon E, Madan-Khetarpal S, Rawlins L, Rustad CF, Stray-Pedersen A, Tveten K, Wenger O, Diaz J, Jenkins L, Martin L, McGuire M, Pietryga M, Ramsdell L, Slattery L, , Abid F, Bertuch AA, Grange D, Immken L, Schaaf CP, Van Esch H, Bi W, Cheung SW, Breman AM, Smith JL, Shaw C, Crosby AH, Eng C, Yang Y, Lupski JR, Xiao R, Liu P. "Clinical exome sequencing reveals locus heterogeneity and phenotypic variability of cohesinopathies." Genetics in medicine : official journal of the American College of Medical Genetics.. 2019 Mar; 21(3):663-675. Epub 2018 Aug 30.

Lee BH, Reijnders MRF, Abubakare O, Tuttle E, Lape B, Minks KQ, Stodgell C, Bennetto L, Kwon J, Fong CT, Gripp KW, Marsh ED, Smith WE, Huq AM, Coury SA, Tan WH, Solis O, Mehta RI, Leventer RJ, Baralle D, Hunt D, Paciorkowski AR. "Expanding the neurodevelopmental phenotype of PURA syndrome." American journal of medical genetics. Part A.. 2018 Jan; 176(1):56-67. Epub 2017 Nov 17.

Weiss K, Terhal PA, Cohen L, Bruccoleri M, Irving M, Martinez AF, Rosenfeld JA, Machol K, Yang Y, Liu P, Walkiewicz M, Beuten J, Gomez-Ospina N, Haude K, Fong CT, Enns GM, Bernstein JA, Fan J, Gotway G, Ghorbani M, , van Gassen K, Monroe GR, van Haaften G, Basel-Vanagaite L, Yang XJ, Campeau PM, Muenke M. "De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms." American journal of human genetics.. 2016 Oct 6; 99(4):934-941. Epub 2016 Sep 08.

Books & Chapters

Chapter Title: Osteogenesis Imperfecta
Book Title: The Pediatric Clinical Advisor
Author List: Fong C-T
Edited By: Garfunkel L, Kaczorowsky J, Christy C
Published By: Mosby 2005 in St. Louis, MO

Chapter Title: Inherited Disorders of Metabolism
Book Title: The Merck Manual
Author List: Fong C-T
Edited By: Beers MH
Published By: Merck Research Laboratories 2005 in Whitehouse Station, NJ

Chapter Title: Turner syndrome
Book Title: The Pediatric Clinical Advisor
Author List: Fong C-T, Artman H
Edited By: Garfunkel L, Kaczorowsky J, Christy C
Published By: Mosby 2005 in St. Louis, MO




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