Chin-To Fong, M.D.

Contact Information

Phone Numbers

Appointment: (585) 275-5857

Office: (585) 275-5857

Fax: (585) 273-1018

A member of the University of Rochester Medical Faculty Group

An Accountable Health Partner

Accepting New Patients

Locations

125 Red Creek Dr
Rochester, NY 14623

Faculty Appointments

Professor - Department of Pediatrics , Genetics (SMD)
Professor - Department of Health Humanities and Bioethics (SMD) - Joint
Professor - Department of Medicine , Genetics (SMD) - Joint
Professor - Department of Biochemistry and Biophysics (SMD) - Joint

Patient Care Settings

Cancer, Genetics, Medicine, Pediatrics

Biography

Dr, Fong provide care for newborns, children, teens, and adults who have genetic and metabolic disorders. He treats a variety of conditions, including birth defects, chromosome abnormalities, cystic fibrosis, developmental disabilities, Fragile X syndrome, Neurofibromatosis, Marfan syndrome, Prader-Willi and Angelman syndrome, Skeletal dysplasias and inborn errors of metabolism, including Medium-Chain Acyl-CoA Dehydrogenase deficiency (MCADD) and Phenylketonuria (PKU).

Dr. Fong has extensive experience working in his field and the Chief of Pediatric Genetics.

Research

Dr. Fong's primary research interest is Genetics of orofacial clefts. Cleft lip and palate is a common birth defect that affects one in 700 children in the U. S. and around the world. Children with this birth defect face multiple challenges, such as feeding difficulty, hearing impairment, speech defects and many dental abnormalities. These problems, along with the cosmetic changes associated with the clefts, often result in life-long physical, educational and psychological handicaps. Caring of these children thus requires a team approach over long periods of time.

Cleft lip and palate is a familial trait, but the genetic factors that result in this abnormality have not been clearly identified. Recent calculations have led to the belief that as many as a couple dozen genetic factors may act together to cause cleft lip and palate, with a few of the factors being more important than the rest. Moreover, there is convincing evidence that environment factors, such as cigarette smoking by the pregnant mother, play a role in the development of cleft lip and palate in the fetus.

In these situations, the environmental and genetic factors act together to cause the birth defect. Therefore, cleft lip and palate is considered a multifactorial genetic disorder. The work in our laboratory is focused on finding the genetic factors for cleft lip and palate through linkage disequilibrium analyses. We believe that better treatment and prevention of cleft lip and palate will come from a better understanding of these genetic and environmental factors.

Credentials

Education

1981
MD | Harvard Medical School

Post-doctoral Training & Residency

07/01/1984 - 06/30/1987
Fellowship at St. Louis University Nephrology Fellowship Program

07/01/1982 - 06/30/1984
Residency in Pediatrics at Washington University School Of Medicine

07/01/1981 - 06/30/1982
Internship in Pediatrics at Washington University School Of Medicine

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Awards

2014
Arnold P. Gold Humanism Honor Society Inductee
Sponsor: Arnold P. Gold Foundation

2012
The Association of American Medical Colleges Arnold P. Gold Foundation Humanism in Medicine Award
Sponsor: Arnold P. Gold Foundation

2009
Elected Student Marshall for Commencement Exercise
Sponsor: URSMD

2008
Elected Alpha Omega Alpha Zeta Chapter Annual Lecturer
Sponsor: Class of 2008 AOA inductees, URSMD

2007 - 2013
Leonard Tow Humanism in Medicine Award
Sponsor: Arnold P. Gold Foundation

2007
Gold Medal Award for Excellence in Teaching
Sponsor: Alumni Association, URSMD

2004 - 2005
Manuel D. Goldman Prize for Excellence in First Year Teaching
Sponsor: University of Rochester School of Med. and Dent.
Location: Rochester, NY

2004
Elected member of Alpha Omega Alpha Zeta Chapter
Sponsor: Class of 2005, URSMD

2004
First Annual Loss Science Lecturer
Sponsor: St. John Fisher College
Location: Rochester, NY

2004
Elected Faculty Commencement Speaker
Sponsor: the URSMD Class of 2004

2004
Outstanding Faculty Teaching Award
Sponsor: Medical Students Class of 2005

2003
Commendation for First Year Teaching
Sponsor: URSMD

2003
URSMD Nominee of the American Association of Medical Colleges Award for Humanism in Medicine
Sponsor: Received commendation from the American Assoc. Medical Colleges

2002 - 2003
DeWitt Brower Dean's Teaching Fellowship
Sponsor: URSMD

2002
Manuel D. Goldman Prize for Excellence in First Year Teaching
Sponsor: URSMD

2001
Ruth A. Lawrence Academic Faculty Service Award, Department of Pediatrics,
Sponsor: URSMD

1993 - 1994
Outstanding Faculty Teaching Award given by the Pediatrics Housestaff
Sponsor: Strong Memorial Hospital

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Publications

Journal Articles

3/2019
Yuan B, Neira J, Pehlivan D, Santiago-Sim T, Song X, Rosenfeld J, Posey JE, Patel V, Jin W, Adam MP, Baple EL, Dean J, Fong CT, Hickey SE, Hudgins L, Leon E, Madan-Khetarpal S, Rawlins L, Rustad CF, Stray-Pedersen A, Tveten K, Wenger O, Diaz J, Jenkins L, Martin L, McGuire M, Pietryga M, Ramsdell L, Slattery L, , Abid F, Bertuch AA, Grange D, Immken L, Schaaf CP, Van Esch H, Bi W, Cheung SW, Breman AM, Smith JL, Shaw C, Crosby AH, Eng C, Yang Y, Lupski JR, Xiao R, Liu P. "Clinical exome sequencing reveals locus heterogeneity and phenotypic variability of cohesinopathies." Genetics in medicine : official journal of the American College of Medical Genetics.. 2019 Mar; 21(3):663-675. Epub 2018 Aug 30.

1/2018
Lee BH, Reijnders MRF, Abubakare O, Tuttle E, Lape B, Minks KQ, Stodgell C, Bennetto L, Kwon J, Fong CT, Gripp KW, Marsh ED, Smith WE, Huq AM, Coury SA, Tan WH, Solis O, Mehta RI, Leventer RJ, Baralle D, Hunt D, Paciorkowski AR. "Expanding the neurodevelopmental phenotype of PURA syndrome." American journal of medical genetics. Part A.. 2018 Jan; 176(1):56-67. Epub 2017 Nov 17.

10/6/2016
Weiss K, Terhal PA, Cohen L, Bruccoleri M, Irving M, Martinez AF, Rosenfeld JA, Machol K, Yang Y, Liu P, Walkiewicz M, Beuten J, Gomez-Ospina N, Haude K, Fong CT, Enns GM, Bernstein JA, Fan J, Gotway G, Ghorbani M, , van Gassen K, Monroe GR, van Haaften G, Basel-Vanagaite L, Yang XJ, Campeau PM, Muenke M. "De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms." American journal of human genetics.. 2016 Oct 6; 99(4):934-941. Epub 2016 Sep 08.

Books & Chapters

2005
Chapter Title: Osteogenesis Imperfecta
Book Title: The Pediatric Clinical Advisor
Author List: Fong C-T
Edited By: Garfunkel L, Kaczorowsky J, Christy C
Published By: Mosby 2005 in St. Louis, MO

2005
Chapter Title: Inherited Disorders of Metabolism
Book Title: The Merck Manual
Author List: Fong C-T
Edited By: Beers MH
Published By: Merck Research Laboratories 2005 in Whitehouse Station, NJ

2005
Chapter Title: Turner syndrome
Book Title: The Pediatric Clinical Advisor
Author List: Fong C-T, Artman H
Edited By: Garfunkel L, Kaczorowsky J, Christy C
Published By: Mosby 2005 in St. Louis, MO

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