Research Bio
~Genomics
~Epigenetics
~Hematology
The Steiner laboratory utilizes genomics techniques to study the molecular mechanisms underlying erythroid maturation and development. The laboratory is particularly interested in studying how specific DNA sequences, DNA binding proteins, and chromatin structure interact during normal erythropoiesis. The laboratory is also interested in studying how those interactions are perturbed in disease states.
2016 Sep 6
Li Y, Schulz VP, Deng C, Li G, Shen Y, Tusi BK, Ma G, Stees J, Qiu Y, Steiner LA, Zhou L, Zhao K, Bungert J, Gallagher PG, Huang S. "Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation." Nucleic acids research. 2016 Sep 6; 44(15):7173-88. Epub 2016 May 03. |
2015 Jun
Malik J, Getman M, Steiner LA. "Histone methyltransferase Setd8 represses Gata2 expression and regulates erythroid maturation." Molecular and cellular biology. 2015 Jun; 35(12):2059-72. Epub 2015 Apr 06. |
2014 Jul
Getman M, England SJ, Malik J, Peterson K, Palis J, Steiner LA. "Extensively self-renewing erythroblasts derived from transgenic ?-yac mice is a novel model system for studying globin switching and erythroid maturation." Experimental hematology. 2014 Jul; 42(7):536-46.e8. Epub 2014 Apr 02. |
2013 Mar 22
Su MY, Steiner LA, Bogardus H, Mishra T, Schulz VP, Hardison RC, Gallagher PG. "Identification of biologically relevant enhancers in human erythroid cells." The Journal of biological chemistry. 2013 Mar 22; 288(12):8433-44. Epub 2013 Jan 22. |
2012 Oct 25
Yocum AO, Steiner LA, Seidel NE, Cline AP, Rout ED, Lin JY, Wong C, Garrett LJ, Gallagher PG, Bodine DM. "A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter." Blood. 2012 Oct 25; 120(17):3586-93. Epub 2012 Sep 11. |
