Jason H. Mendler, M.D., Ph.D.

Jason H. Mendler, M.D., Ph.D.

Contact Information

Box 704

Administrative: (585) 275-4099
Fax: (585) 273-1051

Journal Articles

Showing all 19 journal articles available.

2015 Oct
Khalife J, Radomska HS, Santhanam R, Huang X, Neviani P, Saultz J, Wang H, Wu YZ, Alachkar H, Anghelina M, Dorrance A, Curfman J, Bloomfield CD, Medeiros BC, Perrotti D, Lee LJ, Lee RJ, Caligiuri MA, Pichiorri F, Croce CM, Garzon R, Guzman ML, Mendler JH, Marcucci G. "Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia." Leukemia. 2015 Oct; 29(10):1981-92. Epub 2015 May 14.
2015 Mar
Niederwieser C, Kohlschmidt J, Volinia S, Whitman SP, Metzeler KH, Eisfeld AK, Maharry K, Yan P, Frankhouser D, Becker H, Schwind S, Carroll AJ, Nicolet D, Mendler JH, Curfman JP, Wu YZ, Baer MR, Powell BL, Kolitz JE, Moore JO, Carter TH, Bundschuh R, Larson RA, Stone RM, Mrózek K, Marcucci G, Bloomfield CD. "Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia." Leukemia. 2015 Mar; 29(3):567-75. Epub 2014 Sep 10.
Sivagnanalingam U, Balys M, Eberhardt A, Wang N, Myers JR, Ashton JM, Becker MW, Calvi LM, Mendler JH. "Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia." PloS one. 2015 10(7):e0132375. Epub 2015 Jul 15.
2014 Aug
Becker H, Maharry K, Mrózek K, Volinia S, Eisfeld AK, Radmacher MD, Kohlschmidt J, Metzeler KH, Schwind S, Whitman SP, Mendler JH, Wu YZ, Nicolet D, Paschka P, Powell BL, Carter TH, Wetzler M, Kolitz JE, Carroll AJ, Baer MR, Caligiuri MA, Stone RM, Marcucci G, Bloomfield CD. "Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8." Leukemia. 2014 Aug; 28(8):1754-8. Epub 2014 Mar 21.
2014 Jun
Whitman SP, Kohlschmidt J, Maharry K, Volinia S, Mrózek K, Nicolet D, Schwind S, Becker H, Metzeler KH, Mendler JH, Eisfeld AK, Carroll AJ, Powell BL, Carter TH, Baer MR, Kolitz JE, Park IK, Stone RM, Caligiuri MA, Marcucci G, Bloomfield CD. "GAS6 expression identifies high-risk adult AML patients: potential implications for therapy." Leukemia. 2014 Jun; 28(6):1252-8. Epub 2013 Dec 11.
2014 Apr
Alachkar H, Santhanam R, Maharry K, Metzeler KH, Huang X, Kohlschmidt J, Mendler JH, Benito JM, Hickey C, Neviani P, Dorrance AM, Anghelina M, Khalife J, Tarighat SS, Volinia S, Whitman SP, Paschka P, Hoellerbauer P, Wu YZ, Han L, Bolon BN, Blum W, Mrózek K, Carroll AJ, Perrotti D, Andreeff M, Caligiuri MA, Konopleva M, Garzon R, Bloomfield CD, Marcucci G. "SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome." The Journal of clinical investigation. 2014 Apr; 124(4):1512-24. Epub 2014 Mar 03.
2014 Feb 20
Marcucci G, Yan P, Maharry K, Frankhouser D, Nicolet D, Metzeler KH, Kohlschmidt J, Mrózek K, Wu YZ, Bucci D, Curfman JP, Whitman SP, Eisfeld AK, Mendler JH, Schwind S, Becker H, Bär C, Carroll AJ, Baer MR, Wetzler M, Carter TH, Powell BL, Kolitz JE, Byrd JC, Plass C, Garzon R, Caligiuri MA, Stone RM, Volinia S, Bundschuh R, Bloomfield CD. "Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score." Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2014 Feb 20; 32(6):548-56. Epub 2013 Dec 30.
2014 Feb
Mendler JH, Marcucci G, Bloomfield CD. "Reply to "rare coincident NPM1 and RUNX1 mutations in intermediate risk acute myeloid leukemia display similar patterns to single mutated cases". Haematologica 2014;99(2):e20-21." Haematologica. 2014 Feb; 99(2):e22.
Brown JT, Burack WR, Becker MW, Vlad-Vonica R, Nadasdy T, Bennett JM, Mendler JH. "Extracellular crystals in plasma cell myeloma." Leukemia research reports. 2014 3(2):49-50. Epub 2014 Jun 18.
2013 Oct
Metzeler KH, Maharry K, Kohlschmidt J, Volinia S, Mrózek K, Becker H, Nicolet D, Whitman SP, Mendler JH, Schwind S, Eisfeld AK, Wu YZ, Powell BL, Carter TH, Wetzler M, Kolitz JE, Baer MR, Carroll AJ, Stone RM, Caligiuri MA, Marcucci G, Bloomfield CD. "A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia." Leukemia. 2013 Oct; 27(10):2023-31. Epub 2013 Jun 14.
2013 Aug
Mendler JH, Maharry K, Becker H, Eisfeld AK, Senter L, Mrózek K, Kohlschmidt J, Metzeler KH, Schwind S, Whitman SP, Khalife J, Caligiuri MA, Klisovic RB, Moore JO, Carter TH, Marcucci G, Bloomfield CD. "In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline." Haematologica. 2013 Aug; 98(8):e92-4. Epub 2013 Jun 10.
2013 May
Marcucci, G; Maharry, KS; Metzeler, KH; Volinia, S; Wu, YZ; Mrózek, K; Nicolet, D; Kohlschmidt, J; Whitman, SP; Mendler, JH; Schwind, S; Becker, H; Eisfeld, AK; Carroll, AJ; Powell, BL; Kolitz, JE; Garzon, R; Caligiuri, MA; Stone, RM; Bloomfield CD. "Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients". J Clin Oncol. 2013; .
2012 Jul 12
Eisfeld AK, Marcucci G, Maharry K, Schwind S, Radmacher MD, Nicolet D, Becker H, Mrózek K, Whitman SP, Metzeler KH, Mendler JH, Wu YZ, Liyanarachchi S, Patel R, Baer MR, Powell BL, Carter TH, Moore JO, Kolitz JE, Wetzler M, Caligiuri MA, Larson RA, Tanner SM, de la Chapelle A, Bloomfield CD. "miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia." Blood. 2012 Jul 12; 120(2):249-58. Epub 2012 Apr 23.
2012 Jul
Whitman SP, Caligiuri MA, Maharry K, Radmacher MD, Kohlschmidt J, Becker H, Mrózek K, Wu YZ, Schwind S, Metzeler KH, Mendler JH, Wen J, Baer MR, Powell BL, Carter TH, Kolitz JE, Wetzler M, Carroll AJ, Larson RA, Marcucci G, Bloomfield CD. "The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia." Leukemia. 2012 Jul; 26(7):1713-7. Epub 2012 Feb 07.
Mendler, JH; Maharry, K; Radmacher, MD, Mrozek, K; Becker, H; Metzeler, KH; Schwind, S; Whitman, SP;Khalife, J; Kohlschmidt, J; Nicolet, D; Powell, BL; Carter, TH; Wetzler, M; Moore, JO; Kolitz, JE; Baer, MR; Carroll, AJ; Larson, RA; Caligiuri, MA; Marcucci, G; Bloomfield, CD. "RUNX 1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures." J Clin Oncol. 2012; .
2009 Apr
Mendler JH, Friedberg JW. "Salvage therapy in Hodgkin's lymphoma." The oncologist. 2009 Apr; 14(4):425-32. Epub 2009 Apr 02.
2008 Oct
Mendler JH, Kelly J, Voci S, Marquis D, Rich L, Rossi RM, Bernstein SH, Jordan CT, Liesveld J, Fisher RI, Friedberg JW. "Bortezomib and gemcitabine in relapsed or refractory Hodgkin's lymphoma." Annals of oncology : official journal of the European Society for Medical Oncology. 2008 Oct; 19(10):1759-64. Epub 2008 May 25.
2005 Nov
Mendler J. "A medical experience that taught me about humanism in medicine." Academic medicine : journal of the Association of American Medical Colleges. 2005 Nov; 80(11):1066.
1998 Jan
Lissy NA, Van Dyk LF, Becker-Hapak M, Vocero-Akbani A, Mendler JH, Dowdy SF. "TCR antigen-induced cell death occurs from a late G1 phase cell cycle check point." Immunity. 1998 Jan; 8(1):57-65.